Prolonged exposure to glucose degradation products impairs viability and function of human peritoneal mesothelial cells

Journal of the American Society of Nephrology

Volumn 12, Issue 11, 2001, Pages 2434-2441

  Witowski, J ^a   Wisniewska, J ^a   Korybalska, K ^a   Bender, T O ^a   Breborowicz, A ^a   Gahl, G M ^a   Frei, U ^a   Passlick Deetjen, J ^a   Jorres A ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; CYTOKINE; FIBRONECTIN; FORMALDEHYDE; FURFURAL; GLUCOSE DEGRADATION PRODUCT; GLUCOSE DERIVATIVE; GLYOXAL; INTERLEUKIN 6; METHYLGLYOXAL; PERITONEAL DIALYSIS FLUID; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; MESOTHELIUM CELL; PERITONEAL DIALYSIS; PRIORITY JOURNAL;

EID: 0034752646     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Heat sterilization of glucose-containing fluids for peritoneal dialysis: Biological consequences of chemical alterations
2. Impact of terminal heat sterilization on the quality of peritoneal dialysis solutions
3. Heat sterilization of fluids for peritoneal dialysis gives rise to aldehydes
4. Effect of two-chambered bicarbonate lactate-buffered peritoneal dialysis fluids on peripheral blood mononuclear cell and polymorphonuclear cell function in vitro
5. Effect of glucose degradation products on human peritoneal mesothelial cell function
6. Glucose degradation products: Relationship with cell damage
7. Are aldehydes in heat-sterilized peritoneal dialysis fluids toxic in vitro?
8. Isolation, culture and characterization of human peritoneal mesothelial cells
9. Effect of phosphatidylcholine on the function of human mesothelial cells in vitro
10. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
11. Effect of N(8)-acetylspermidine deacetylase inhibition on the growth of L 1210 cells
12. Reduced glucose degradation products in bicarbonate/lactate-buffered peritoneal dialysis solutions produced in two-chambered bags
13. Effect of icodextrin peritoneal dialysis solution on cell proliferation in vitro
14. Toxicity of peritoneal dialysis fluids on cultured fibroblasts, L-929
15. Heat sterilized PD-fluids impair growth and inflammatory responses of cultured cell lines and human leukocytes
16. In vitro biocompatibility of a heat-sterilized, low-toxic, and less acidic fluid for peritoneal dialysis
17. Effects of a pH 7.4, lactate-based and a pH 7.4, bicarbonatebased peritoneal dialysis solutions on neutrophil superoxide generation
18. Adherence of Staphylococci to plastic, mesothelial cells and mesothelial extracellular matrix
19. Epidermal growth factor modifies the expression and function of extracellular matrix adhesion receptors expressed by peritoneal mesothelial cells from patients on CAPD
20. Fibronectins-Adhesive glycoproteins of cell surface and blood
21. Cerebrospinal fluid concentration of fibronectin in patients with HIV-I infection and central nervous system disorders
22. Fibronectin and complement secretion by monocytes and peritoneal macrophages in vitro from patients undergoing continuous ambulatory peritoneal dialysis
23. Fibronectin during CAPD-related peritonitis: No indications for intraperitoneal production
24. Isolation and propagation in vitro of peritoneal mesothelial cells
25. Effects of osmotic solutes on fibronectin mRNA expression in rat peritoneal mesothelial cells
26. Extracellular matrix proteins modulate human peritoneal mesothelial cell behavior
27. Mesothelial cell adherence to vascular prostheses and their subsequent growth in vitro
28. Immuno-effector characteristics of peritoneal cells during CAPD treatment: A longitudinal study
29. The mesothelial cells in CAPD effluent and their relation to peritonitis incidence
30. Less infusion pain and elevated level of cancer antigen 125 by the use of a new and more biocompatible PD fluid
31. Clinical and physiological effects of a new, less toxic and less acidic fluid for peritoneal dialysis
32. Low concentrations of glucose degradation products in peritoneal dialysis fluids and their impact on biocompatibility parameters: Prospective cross-over study with a three-compartment bag
33. Long-term clinical effects of a peritoneal dialysis fluid with less glucose degradation products
34. 3-Deoxyglucosone, a promoter of advanced glycation end products in fluids for peritoneal dialysis
35. Does exposure to 3-deoxyglucosone affect cytokine production by human peritoneal mesothelial cells?
36. Glycerol toxicity for human peritoneal mesothelial cells in culture: Comparison with glucose
37. Toxicity of osmotic solutes on human mesothelial cells in vitro
38. Alterations in nonenzymatic biochemistry in uremia: Origin and significance of "carbonyl stress" in long-term uremic complications
39. In vitro AGE formation with methylglyoxal-a glucose breakdown product in diabetic sera and PD fluid