Formaldehyde exposure impairs the function and differentiation of NK cells

Toxicology Letters

Volumn 223, Issue 2, 2013, Pages 154-161

  Kim, Eun Mi ^a,e   Lee, Hwa Youn ^a   Lee, Eun Hee ^a   Lee, Ki Mo ^b   Park, Min ^a   Ji, Kon Young ^a   Jang, Ji Hun ^a   Jeong, Yun Hwa ^a   Lee, Kwang Ho ^a   Yoon, Il Joo ^a   Kim, Su Man ^a   Jeong, Moon Jin ^c   Kim, Kwang Dong ^d   Kang, Hyung Sik ^a  

^a Chonnam National University   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^c Chosun University   (South Korea)

^d Gyeongsang National University   (South Korea)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

Differentiation; Formaldehyde; Natural killer cell

Indexed keywords

CD22 ANTIGEN; FORMALDEHYDE; GAMMA INTERFERON; PERFORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CARCINOGENICITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXPOSURE; FEMALE; GENE EXPRESSION; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MELANOMA CELL; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE; TUMOR GROWTH; TUMOR VOLUME;

BALF; BM; BONE MARROW; BRONCHOALVEOLAR LAVAGE FLUID; DIFFERENTIATION; FA; FORMALDEHYDE; HEMATOPOIETIC STEM CELLS; HSCS; IFN-Γ; INTERFERON-Γ; LIPOPOLYSACCHARIDE; LPS; MATURE NK; MNK; NATURAL KILLER CELL; NK CELL; NK PRECURSOR; PNK;

ANIMALS; B-LYMPHOCYTES; BRONCHOALVEOLAR LAVAGE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL SURVIVAL; FEMALE; FORMALDEHYDE; KILLER CELLS, NATURAL; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; T-LYMPHOCYTES;

EID: 84886234093     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.09.008     Document Type: Article

References (23)

1. Andersen M.E., Clewell H.J., Bermudez E., Willson G.A., Thomas R.S. Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat. Toxicol. Sci. 2008, 105:368-383.
2. Beane Freeman L.E., Blair A., Lubin J.H., Stewart P.A., Hayes R.B., Hoover R.N., Hauptmann M. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort. J. Natl. Cancer Inst. 2009, 101:751-761.
3. Bendelac A., Rivera M.N., Park S.H., Roark J.H. Mouse CD1-specific NK1T cells: development, specificity, and function. J. Natl. Cancer Inst. 1997, 15:535-562.
4. Cheng M., Zhang J., Jiang W., Chen Y., Tian Z. Natural killer cell lines in tumor immunotherapy. Front. Med. 2012, 6:56-66.
5. + T cell immunity to reject established tumors. Blood 2006, 107:1342-1351.
6. Fujimaki H., Imai T., Befus D. Mast cell response to formaldehyde. Int. Arch. Allergy Immunol. 1992, 98:332-338.
7. Fujimaki H., Kurokawa Y., Kunugita N., Kikuchi M., Sato F., Arashidani K. Differential immunogenic and neurogenic inflammatory responses in an allergic mouse model exposed to low levels of formaldehyde. Toxicology 2004, 197:1-13.
8. Hosgood H.D., Zhang L., Tang X., Vermeulen R., Hao Z., Shen M., Qiu C., Ge Y., Hua M., Ji Z., Li S., Xiong J., Reiss B., Liu S., Xin K.X., Azuma M., Xie Y., Freeman L.B., Ruan X., Guo W., Galvan N., Blair A., Li L., Huang H., Smith M.T., Rothman N., Lan Q. Occupational exposure to formaldehyde and alterations in lymphocyte subsets. Am. J. Ind. Med. 2012, 10.1002/ajim.22088.
9. International Agency for Research on Cancer (IARC) Formaldehyde, 2-Butoxyethanol and 1-Tert-Butoxypropanol-2-ol. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 88 2006, 39-325. World Health Organization, Lyon.
10. Intlekofer A.M., Takemoto N., Wherry E.J., Longworth S.A., Northrup J.T., Palanivel V.R., Mullen A.C., Gasink C.R., Kaech S.M., Miller J.D., Gapin L., Ryan K., Russ A.P., Lindsten T., Orange J.S., Goldrath A.W., Ahmed R., Reiner S.L. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 2005, 6:1236-1244.
11. Jung W.W., Kim E.M., Lee E.H., Yoon H.J., Ju H.R., Jeong M.J., Hwang K.W., Sul D., Kang H.S. Formaldehyde exposure induces airway inflammation by increasing eosinophil infiltrations through the regulation of reactive oxygen species production. Environ. Toxicol. Pharmacol. 2007, 24:174-182.
12. Karre K., Ljunggren H.G., Piontek G., Kiessling R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 1986, 319:675-678.
13. Kerns W.D., Pavkov K.L., Donofrio D.J., Gralla E.J., Swenberg J.A. Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure. Cancer Res. 1983, 43:4382-4392.
14. Kim S., Iizuka K., Kang H.S., Dokun A., French A.R., Greco S., Yokoyama W.M. In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 2002, 3:523-528.
15. Kulle T.J., Sauder L.R., Hebel J.R., Hebal J.R., Green D.J., Chatham M.D. Formaldehyde dose-response in healthy nonsmokers. JAPCA 1987, 37:919-924.
16. Lee K.N., Kang H.S., Jeon J.H., Kim E.M., Yoon S.R., Song H., Lyu C.Y., Piao Z.H., Kim S.U., Han Y.H., Song S.S., Lee Y.H., Song K.S., Kim Y.M., Yu D.Y., Choi I. VDUP1 is required for the development of natural killer cells. Immunity 2005, 22:195-208.
17. Liteplo R.G., Meek M.E. Inhaled formaldehyde: exposure estimation, hazard characterization, and exposure-response analysis. J. Toxicol. Environ. Health B Crit. Rev. 2003, 6:85-114.
18. Michel T., Poli A., Domingues O., Mauffray M., Thérésine M., Brons N.H., Hentges F., Zimmer J. Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages. PLoS ONE 2012, 7:e51230.
19. Pinkerton L.E., Hein M.J., Stayner L.T. Mortality among a cohort of garment workers exposed to formaldehyde: an update. Occup. Environ. Med. 2004, 61:193-200.
20. Raulet D.H., Guerra N. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat. Rev. Immunol. 2009, 9:568-580.
21. Stinchcombe J.C., Griffiths G.M. Secretory mechanisms in cell-mediated cytotoxicity. Annu. Rev. Cell Dev. Biol. 2007, 23:495-517.
22. Tajima K., Matsumoto N., Ohmori K., Wada H., Ito M., Suzuki K., Yamamoto K. Augmentation of NK cell-mediated cytotoxicity to tumor cells by inhibitory NK cell receptor blockers. Int. Immunol. 2004, 16:385-393.
23. Trapani J.A., Davis J., Sutton V.R., Smyth M.J. Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo. Curr. Opin. Immunol. 2000, 12:323-329.