Differential effects of triclosan on the activation of mouse and human peroxisome proliferator-activated receptor alpha

Toxicology Letters

Volumn 231, Issue 1, 2014, Pages 17-28

  Wu, Yuanfeng ^a   Wu, Qiangen ^a,b   Beland, Frederick A ^a   Ge, Peter ^a   Manjanatha, Mugimane G ^a   Fang, Jia Long ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Apoptosis; DNA synthesis; PPAR ; Triclosan

Indexed keywords

ACYL COENZYME A OXIDASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TRICLOSAN; ANTIINFECTIVE AGENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; DRUG CYTOTOXICITY; HEPA1C1C7 CELL LINE; HEPATOCELLULAR CARCINOMA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN TARGETING; AGONISTS; ANIMAL; CELL PROLIFERATION; COMPARATIVE STUDY; DNA REPLICATION; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; IC50; LIVER; METABOLISM; MOUSE; PATHOLOGY; REPORTER GENE; SPECIES DIFFERENCE; TIME; TOXICITY;

ACYL-COA OXIDASE; ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CELL PROLIFERATION; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, REPORTER; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER; MICE; PPAR ALPHA; SPECIES SPECIFICITY; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRICLOSAN;

EID: 84908287538     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.09.001     Document Type: Article

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