Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors

Clinical Hemorheology and Microcirculation

Volumn 58, Issue 1, 2014, Pages 281-295

  Ullm, Sandra ^a,b   Laube, Markus ^a,b   Bechmann, Nicole ^a,b   Kniess, Torsten ^a   Pietzsch, Jens ^a,b  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

adjuvant radioprotective therapy; Aortic ring model; cardiovascular disease; coxibs; normal tissue damage; prostanoids; radiation therapy

Indexed keywords

2 [4 (AMINOSULFONYL)PHENYL] 3 (4 METHOXYPHENYL) 1H INDOLE; ANTIOXIDANT; ARACHIDONIC ACID; CARBON 11; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; F2ALPHA ISOPROSTANE; FLUORODEOXYGLUCOSE F 18; INDOLE DERIVATIVE; ISOPROSTANE DERIVATIVE; PROSTAGLANDIN E2; RADIOPROTECTIVE AGENT; UNCLASSIFIED DRUG; OXIDIZING AGENT; PROSTAGLANDIN; PTGS2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; RADIATION DOSE DISTRIBUTION; RADIATION PROTECTION; RAT; VASCULAR RING; X IRRADIATION; ANIMAL; AORTA; BIOLOGICAL MODEL; CARDIOVASCULAR DISEASES; CHEMISTRY; DRUG EFFECTS; METABOLISM; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; AORTA; ARACHIDONIC ACID; CARDIOVASCULAR DISEASES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; IMMUNOHISTOCHEMISTRY; INDOLES; ISOPROSTANES; MALE; MODELS, CARDIOVASCULAR; OXIDANTS; PROSTAGLANDINS; RADIATION-PROTECTIVE AGENTS; RATS; RATS, WISTAR;

EID: 84908234279     PISSN: 13860291     EISSN: 18758622     Source Type: Journal    
DOI: 10.3233/CH-141902     Document Type: Article

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