LC-ESI-MS/MS method for oxidative stress multimarker screening in the exhaled breath condensate of asbestosis/silicosis patients

Journal of Breath Research

Volumn 4, Issue 1, 2010, Pages

  Syslova K ^a,b   Kacer P ^a   Kuzma, M ^b   Pankracova A ^a   Fenclova Z ^c   Vlckova S ^c   Lebedova J ^c   Pelclova D ^c  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 HYDROXYPHENYL)ALANINE; 8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTAGLANDIN F2 ALPHA; AMINO ACID; BIOLOGICAL MARKER; NUCLEIC ACID;

ACCURACY; ADULT; AGED; ANALYTIC METHOD; ANALYTICAL EQUIPMENT; ARTICLE; ASBESTOSIS; BREATH ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DEVICE; DNA DAMAGE; ELECTROSPRAY MASS SPECTROMETRY; EXHALED BREATH CONDENSATE; EXPIRED AIR; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIPID OXIDATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; OCCUPATIONAL LUNG DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; SCREENING; SILICOSIS; STATISTICAL SIGNIFICANCE; VALIDATION STUDY; FREEZE DRYING; METABOLISM; METHODOLOGY;

ADULT; ASBESTOSIS; BIOLOGICAL MARKERS; BREATH TESTS; CHROMATOGRAPHY, LIQUID; FEMALE; FREEZE DRYING; HUMANS; MALE; OXIDATIVE STRESS; SILICOSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; YOUNG ADULT;

EID: 76249091883     PISSN: 17527155     EISSN: 17527163     Source Type: Journal    
DOI: 10.1088/1752-7155/4/1/017104     Document Type: Article

References (14)

1. Stadelmann-Ingrand S, Favreliere S, Fauconneau B, Mauco G and Tallineau C 2001 Plasmalogen degradation by oxidative stress: production and disappearance of specific fatty aldehydes and fatty α-hydroxyaldehydes Free Radic. Biol. Med. 31 1263-71
2. Morrow J D and Roberts L J II 1996 The isoprostanes: current knowledge and directions for future research Biochem. Pharmacol. 51 1-9
3. Khatib S, Musa R and Vaya J 2007 An exogenous marker: a novel approach for the characterization of oxidative stress Bioorg. Med. Chem. 15 3661-6
4. Holmerg I, Stal P and Hamberg M 1999 Quantitative determination of 8-hydroxy-2′-deoxyguanosine in human urine by isotope dilution mass spectrometry: normal levels in hemochromatosis Free Radic. Biol. Med. 26 129-35
5. Kim K A et al 2002 Mechanism of silica-induced ROS generation in Rat2 fibroblast cells Toxicol. Lett. 5 185-91
6. Pelclov D, Fenclov Z, Kaer P, Kuzma M, Navrtil T and Lebedov J 2008 Increased 8-isoprostane, a marker of oxidative stress in exhaled breath condensate in subjects with asbestos exposure Ind. Health 46 484-9
7. 4 and 8-isoprostane in exhaled breath condensate in patients with asbestosis Thorax 62 602-7
8. Pelclov D, Fenclov Z, Kaer P, Navrtil T, Kuzma M, Lebedov J and Kluskov J 2007 8-isoprostane and leukotrienes in exhaled breath condensate in Czech subjects with silicosis Ind. Health 45 766-74
9. Milne G L, Musiek E S and Morrow J D 2005 F2-isoprostanes as markers of oxidative stress in vivo: an overview Biomarkers 10 S10-23
10. Kurimoto C et al 2007 Thioredoxin may exert a protective effect against tissue damage caused by oxidative stress in salivary glands of patients with Sjögren's syndrome J. Rheumatol. 34 2035-43
11. Montuschi P 2005 New Perspective in Monitoring Lung Inflammation-Analysis of Exhaled Breath Condensate ed P Montuschi (Boca Rotan, FL: CRC Press) pp 53-66
12. Syslov K, Kaer P, Kuzma M, Kluskov P, Fenclov Z, Lebedov J and Pelclov D 2009 Rapid and easy method for monitoring oxidative stress markers in body fluids of patients with asbestos or silica-induced lung diseases J. Chromatogr. B 877 2477-86
13. 2α in exhaled breath condensate using combination of immunoseparation and LC-ESI-MS/MS J. Chromatogr. B 867 8-14
14. Hua Y, Wainhaus S B, Yang Y, Shen L, Xiong Y, Xu X, Zhagn F, Bolton J L and van Breemen R B 2000 Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides J. Am. Soc. Mass Spectrom. 12 80-7