메뉴 건너뛰기




Volumn 10, Issue 11, 2014, Pages 659-672

Novel metabolic biomarkers of cardiovascular disease

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ADIPONECTIN; BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR 23; HAPTOGLOBIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE; LIPOPROTEIN A; VITAMIN D; 25-HYDROXYVITAMIN D; FIBROBLAST GROWTH FACTOR; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

EID: 84908141562     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2014.155     Document Type: Review
Times cited : (82)

References (197)
  • 1
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2012 update: A report from the American Heart Association
    • Roger V. L. et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 125, e2-e220(2012).
    • (2012) Circulation , vol.125 , pp. e2-e220
    • Roger, V.L.1
  • 2
    • 0034674047 scopus 로고    scopus 로고
    • Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics
    • Prosser L. A . et al. Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics. Ann. Intern. Med. 132, 769-779 (2000).
    • (2000) Ann. Intern. Med , vol.132 , pp. 769-779
    • Prosser, L.A.1
  • 3
    • 84903159932 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the assessment of cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • Goff D. C. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129, S49-S73 (2014).
    • (2014) Circulation , vol.129 , pp. S49-S73
    • Goff, D.C.1
  • 4
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14,719 initially healthy American women
    • Ridker P. M., Buring J. E., Cook N. R. & Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14,719 initially healthy American women. Circulatio n 107, 391-397 (2003).
    • (2003) Circulatio N , vol.107 , pp. 391-397
    • Ridker, P.M.1    Buring, J.E.2    Cook, N.R.3    Rifai, N.4
  • 5
    • 85028095410 scopus 로고    scopus 로고
    • NIH. Third report of the National Cholesterol Education Program (NECP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults adult treatment panel III) final report [online
    • NIH. Third report of the National Cholesterol Education Program (NECP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report [online], http://www.nhlbi.nih.gov/files/docs/resources/heart/atp3full.pdf (2004).
    • (2004)
  • 6
    • 0017384270 scopus 로고
    • High d ensity lipoprotein as a protective factor against coronary heart disease. The Framingham Study
    • Gordon T., Castelli W. P., Hjortland M. C., Kannel W. B. & Dawber T. R. High d ensity lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am. J. Med. 62, 707-714 (1977).
    • (1977) Am. J. Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 7
    • 47149103896 scopus 로고    scopus 로고
    • Lipids, lipoproteins, and apolipoproteins as ris k markers of myocardial infarction in 52 countries (the INTERHEART study): A case-control study
    • McQueen M. J. et al. Lipids, lipoproteins, and apolipoproteins as ris k markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study Lancet 372 224-233 2008).
    • (2008) Lancet , vol.372 , pp. 224-233
    • McQueen, M.J.1
  • 8
    • 70450081001 scopus 로고    scopus 로고
    • Major lipids, apolipoproteins, and risk of vascular disease
    • Di Angelantonio E. et al. Major lipids, apolipoproteins, and risk of vascular disease. JAMA 302, 1993-2000 (2009).
    • (2009) JAMA , vol.302 , pp. 1993-2000
    • Di Angelantonio, E.1
  • 9
    • 79959694696 scopus 로고    scopus 로고
    • A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk
    • Sniderman A. D. et al. A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk. Circ. Cardiovasc. Qual. Outcomes 4, 337-345 (2011).
    • (2011) Circ. Cardiovasc. Qual. Outcomes , vol.4 , Issue.337-345
    • Sniderman, A.D.1
  • 10
    • 0037016049 scopus 로고    scopus 로고
    • Lipid lowering by simvastatin induces regression of human atherosclerotic lesions: Two y ears' follow-up by high-resolution noninvasive magnetic resonance imaging
    • Corti R. et al. Lipid lowering by simvastatin induces regression of human atherosclerotic lesions: two y ears' follow-up by high-resolution noninvasive magnetic resonance imaging. Circulation 106, 2884-2887 (2002).
    • (2002) Circulation , vol.106 , pp. 2884-2887
    • Corti, R.1
  • 11
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • Grundy S. M. et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110, 227-239 (2004).
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1
  • 12
    • 80052094401 scopus 로고    scopus 로고
    • The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline
    • West A. M. et al. The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline. Atherosclerosis 218, 156-162 (2011).
    • (2011) Atherosclerosis , vol.218 , Issue.156-162
    • West, A.M.1
  • 13
    • 50949102416 scopus 로고    scopus 로고
    • Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes
    • Cannon C. P. et al. Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. Am. Heart J. 156, 826-832 (2008).
    • (2008) Am. Heart J , vol.156 , pp. 826-832
    • Cannon, C.P.1
  • 14
    • 41049092691 scopus 로고    scopus 로고
    • Lipid management to reduce cardiovascular risk: A new strategy is required
    • Superko H. R. & King S. III. Lipid management to reduce cardiovascular risk: a new strategy is required. Circulation 117, 560-568 (2008).
    • (2008) Circulation , vol.117 , pp. 560-568
    • Superko, H.R.1    King, S.2
  • 15
    • 41049114551 scopus 로고    scopus 로고
    • Promise of low-density lipoprotein-lowering therapy for primary and secondary prevention
    • Grundy S. M. Promise of low-density lipoprotein-lowering therapy for primary and secondary prevention. Circulation 117, 569-573 (2008).
    • (2008) Circulation , vol.117 , pp. 569-573
    • Grundy, S.M.1
  • 16
    • 33750816249 scopus 로고    scopus 로고
    • Lipoprotein(a a unique risk factor for cardiovascular disease
    • Anuurad E., Boffa M. B., Koschinsky M. L. & Berglund L. Lipoprotein(a): a unique risk factor for cardiovascular disease. Clin. Lab. Med. 26, 751-772 (2006).
    • (2006) Clin. Lab. Med , vol.26 , pp. 751-772
    • Anuurad, E.1    Boffa, M.B.2    Koschinsky, M.L.3    Berglund, L.4
  • 17
    • 0032816711 scopus 로고    scopus 로고
    • Lipoprotein(a): Intrigues and insights
    • Hobbs H. H. & White A. L. Lipoprotein(a): intrigues and insights. Curr. Opin. Lipidol. 10, 225-236 (1999).
    • (1999) Curr. Opin. Lipidol , vol.10 , pp. 225-236
    • Hobbs, H.H.1    White, A.L.2
  • 18
    • 0032542389 scopus 로고    scopus 로고
    • Lipoprotein(a) as a risk factor for coronary artery disease
    • Marcovina S. M. & Koschinsky M. L. Lipoprotein(a) as a risk factor for coronary artery disease. Am. J. Cardiol. 82, 57U-66U (1998).
    • (1998) Am. J. Cardiol , vol.82 , pp. 57U-66U
    • Marcovina, S.M.1    Koschinsky, M.L.2
  • 19
    • 0030868773 scopus 로고    scopus 로고
    • Apolipoprotein(a) induces monocyte chemotactic activity in human vascu lar endothelial cells
    • Poon M., Zhang X., Dunsky K. G., Taubman M. B. & Harpel P. C. Apolipoprotein(a) induces monocyte chemotactic activity in human vascu lar endothelial cells. Circulation 96, 2514-2519 (1997).
    • (1997) Circulation , vol.96 , pp. 2514-2519
    • Poon, M.1    Zhang, X.2    Dunsky, K.G.3    Taubman, M.B.4    Harpel, P.C.5
  • 21
    • 84865125773 scopus 로고    scopus 로고
    • Apolipoprotein(a) genetic sequence variants associated with systemic at herosclerosis and coronary atherosclerotic burden but not with venous thromboembolism
    • Helgadottir A. et al. Apolipoprotein(a) genetic sequence variants associated with systemic at herosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. J. Am. Coll. Cardiol. 60, 722-729 (2012).
    • (2012) J. Am. Coll. Cardiol , vol.60 , Issue.722-729
    • Helgadottir, A.1
  • 22
    • 0031967430 scopus 로고    scopus 로고
    • Increa sed degradation of lipoprotein(a) in atherosclerotic compared with nonlesioned aortic intima-inner media of rabbits: In vivo evidence that lipoprotein(a) may contribute to foam cell formation
    • Nielsen L. B., Juul K. & Nordestgaard B. G. Increa sed degradation of lipoprotein(a) in atherosclerotic compared with nonlesioned aortic intima-inner media of rabbits: in vivo evidence that lipoprotein(a) may contribute to foam cell formation. Arterioscler. Thromb. Vasc. Biol. 18, 641-649 (1998).
    • (1998) Arterioscler. Thromb. Vasc. Biol , vol.18 , pp. 641-649
    • Nielsen, L.B.1    Juul, K.2    Nordestgaard, B.G.3
  • 23
    • 84873044293 scopus 로고    scopus 로고
    • Lipoprotein(a), polymorphisms in the LPA gene, and incident venous thromboembolism among 21,483 women
    • Danik J. S. et al. Lipoprotein(a), polymorphisms in the LPA gene, and incident venous thromboembolism among 21,483 women. J. Thromb. Haemost. 11, 205-208 (2013).
    • (2013) J. Thromb. Haemost , vol.11 , Issue.205-208
    • Danik, J.S.1
  • 24
    • 67651210632 scopus 로고    scopus 로고
    • Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality
    • Erqou S. et al. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA 302, 412-423 (2009).
    • (2009) JAMA , vol.302 , pp. 412-423
    • Erqou, S.1
  • 25
    • 84890461947 scopus 로고    scopus 로고
    • Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: Guidance for clinicians to prevent coronary heart disease: Consensus statement of the European Atherosclerosis Society
    • Nordestgaard B. G. et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur. Heart J. 34, 3478a-3490a (2013).
    • (2013) Eur. Heart J , vol.34 , pp. 3478a-3490a
    • Nordestgaard, B.G.1
  • 26
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E. et al. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J. Clin. Invest. 90, 52-60 (1992).
    • (1992) J. Clin. Invest , vol.90 , pp. 52-60
    • Boerwinkle, E.1
  • 27
    • 0030799057 scopus 로고    scopus 로고
    • The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans
    • Mooser V. et al. The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans. Am. J. Hum. Genet. 61, 402-417 (1997).
    • (1997) Am. J. Hum. Genet , vol.61 , pp. 402-417
    • Mooser, V.1
  • 28
    • 61349137526 scopus 로고    scopus 로고
    • Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
    • Tregouet D. A. et al Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat. Genet.41 283-285 2009).
    • (2009) Nat. Genet , vol.41 , pp. 283-285
    • Tregouet, D.A.1
  • 29
    • 67049167090 scopus 로고    scopus 로고
    • Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
    • Kamstrup P. R., Tybj aerg-Hansen A., Steffensen R. & Nordestgaard B. G. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA 301, 2331-2339 (2009).
    • (2009) JAMA , vol.301 , pp. 2331-2339
    • Kamstrup, P.R.1    Tybj Aerg-Hansen, A.2    Steffensen, R.3    Nordestgaard, B.G.4
  • 30
    • 0037432183 scopus 로고    scopus 로고
    • Association of polymorphisms of the apolipoprotein(a) gene with lipoprotein(a) levels and myocardial infarction
    • Holmer S. R. et al. Association of polymorphisms of the apolipoprotein(a) gene with lipoprotein(a) levels and myocardial infarction. Circulation 107, 696-701 (2003).
    • (2003) Circulation , vol.107 , pp. 696-701
    • Holmer, S.R.1
  • 31
    • 2442520797 scopus 로고    scopus 로고
    • Efficacy of exte nded-release niacin with lovastatin for hypercholesterolemia: Assessing all reasonable doses with innovative surface graph analysis
    • Insull W. Jr et al. Efficacy of exte nded-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis. Arch. Intern. Med. 164, 1121-1127 (2004).
    • (2004) Arch. Intern. Med , vol.164 , pp. 1121-1127
    • Insull, W.1
  • 32
    • 84886070404 scopus 로고    scopus 로고
    • R elationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: The AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes
    • Albers J. J. et al. R elationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglyceride and Impact on Global Health Outcomes). J. Am. Coll. Cardiol. 62, 1575-1579 (2013).
    • (2013) J. Am. Coll. Cardiol , vol.62 , pp. 1575-1579
    • Albers, J.J.1
  • 33
    • 84905167398 scopus 로고    scopus 로고
    • Extended-release niacin/laropiprant improves endothelial function in patients after myocardial inf arction
    • Bregar U., Jug B., Keber I., Cevc M. & Sebestjen M. Extended-release niacin/laropiprant improves endothelial function in patients after myocardial inf arction. Heart Vessels 29, 313-319 (2013).
    • (2013) Heart Vessels , vol.29 , pp. 313-319
    • Bregar, U.1    Jug, B.2    Keber, I.3    Cevc, M.4    Sebestjen, M.5
  • 34
    • 77952397461 scopus 로고    scopus 로고
    • Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis
    • Bruckert E., Labreuche J. & Amarenco P. Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis 210, 353-361 (2010).
    • (2010) Atherosclerosis , vol.210 , Issue.353-361
    • Bruckert, E.1    Labreuche, J.2    Amarenco, P.3
  • 35
    • 84877299845 scopus 로고    scopus 로고
    • HPS2-THRIVE randomized placebo-controlled trial in 25,673 high-risk patients of ER niacin/laro piprant: Trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
    • HSP2-THRIVE Collaborative Group
    • HSP2-THRIVE Collaborative Group. HPS2-THRIVE randomized placebo-controlled trial in 25,673 high-risk patients of ER niacin/laro piprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. Eur. Heart J. 34, 1279-1291 (2013).
    • (2013) Eur. Heart J , vol.34 , pp. 1279-1291
  • 36
    • 84855849500 scopus 로고    scopus 로고
    • Atorvastatin decreases lipoprotein(a): A meta-analysis of randomized trials
    • Takagi H. & Umemoto T. Atorvastatin decreases lipoprotein(a): a meta-analysis of randomized trials. Int. J. Cardiol. 154, 183-186 (2012).
    • (2012) Int. J. Cardiol , vol.154 , pp. 183-186
    • Takagi, H.1    Umemoto, T.2
  • 37
    • 0028877052 scopus 로고
    • Effects of lowering elevated LDL cholesterol on the cardiovascular risk of lipoprotein(a
    • Maher V. M. et al. Effects of lowering elevated LDL cholesterol on the cardiovascular risk of lipoprotein(a). JAMA 274, 1771-1774 (1995).
    • (1995) JAMA , vol.274 , pp. 1771-1774
    • Maher, V.M.1
  • 38
    • 0031409345 scopus 로고    scopus 로고
    • Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study
    • Berg K. et al. Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study. Clin. Genet. 52, 254-261 (1997).
    • (1997) Clin. Genet , vol.52 , pp. 254-261
    • Berg, K.1
  • 39
    • 79953699040 scopus 로고    scopus 로고
    • Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice
    • Merki E. et al. Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice. J. Am. Coll. Cardiol. 57, 1611-1621 (2011).
    • (2011) J. Am. Coll. Cardiol , vol.57 , pp. 1611-1621
    • Merki, E.1
  • 40
    • 50349084487 scopus 로고    scopus 로고
    • Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice
    • Merki E. et al. Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice . Circulation 118, 743-753 (2008).
    • (2008) Circulation , vol.118 , pp. 743-753
    • Merki, E.1
  • 41
    • 84870065743 scopus 로고    scopus 로고
    • Emerging therapeutic agents to lower lipoprotein (a) levels
    • Kolski B. & Tsimikas S. Emerging therapeutic agents to lower lipoprotein (a) levels. Curr. Opin. Lipidol. 23, 560-568 (2012).
    • (2012) Curr. Opin. Lipidol , vol.23 , Issue.560-568
    • Kolski, B.1    Tsimikas, S.2
  • 42
    • 80054814637 scopus 로고    scopus 로고
    • Oxidized phospholipids on apoB-100-containing lipoproteins: A biomarker predicting cardiovascular disease and cardiovascular events
    • Taleb A., Witztum J. L. & Tsimikas S. Oxidized phospholipids on apoB-100-containing lipoproteins: a biomarker predicting cardiovascular disease and cardiovascular events. Biomar k. Med. 5, 673-694 (2011).
    • (2011) Biomar K. Med , vol.5 , pp. 673-694
    • Taleb, A.1    Witztum, J.L.2    Tsimikas, S.3
  • 43
    • 84877987644 scopus 로고    scopus 로고
    • Oxidation-specific biomarkers and risk of peripheral artery disease
    • Bertoia M. L. et al. Oxidation-specific biomarkers and risk of peripheral artery disease. J. Am. Coll. Cardiol. 61, 2169-2179 (2013).
    • (2013) J. Am. Coll. Cardiol , vol.61 , pp. 2169-2179
    • Bertoia, M.L.1
  • 44
    • 84859178956 scopus 로고    scopus 로고
    • Antioxidant vitamins in atherosclerosis-animal experiments and clinical studies
    • Ozkanlar S. & Akcay, F. Antioxidant vitamins in atherosclerosis-animal experiments and clinical studies. Adv. Clin. Exp. Med. 21, 115-123 (2012).
    • (2012) Adv. Clin. Exp. Med , vol.21 , Issue.115-123
    • Ozkanlar, S.1    Akcay, F.2
  • 45
    • 33751028489 scopus 로고    scopus 로고
    • The phospholipase A2 superfamily and its group numbering system
    • Schaloske R. H. & Dennis E. A. The phospholipase A2 superfamily and its group numbering system. Biochim. Biophys. Acta 1761, 1246-1259 (2006).
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 1246-1259
    • Schaloske, R.H.1    Dennis, E.A.2
  • 46
    • 0033517041 scopus 로고    scopus 로고
    • Cellular source(s) of platelet-activating-factor acetylhydrolase activity in plasma
    • Asano K. et al. Cellular source(s) of platelet-activating-factor acetylhydrolase activity in plasma. Biochem. Biophys. Res. Commun. 261, 511-514 (1999).
    • (1999) Biochem. Biophys. Res. Commun , vol.261 , pp. 511-514
    • Asano, K.1
  • 47
    • 0036159510 scopus 로고    scopus 로고
    • Atorvastatin preferentially reduces LDL-associated platelet-activati ng factor acetylhydrolase activity in dyslipidemias of type IIA and type IIB
    • Tsimihodimos V. et al. Atorvastatin preferentially reduces LDL-associated platelet-activati ng factor acetylhydrolase activity in dyslipidemias of type IIA and type IIB. Arterioscler. Thromb. Vasc. Biol. 22, 306-311 (2002).
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 306-311
    • Tsimihodimos, V.1
  • 48
    • 0023180687 scopus 로고
    • Human plasma platelet-activating factor acetylhydrolase. Purification and properties
    • Stafforini D. M., Prescott S. M. & McIntyre T. M. Human plasma platelet-activating factor acetylhydrolase. Purification and properties. J. Biol. Chem. 262, 4223-4230 (1987).
    • (1987) J. Biol. Chem , vol.262 , pp. 4223-4230
    • Stafforini, D.M.1    Prescott, S.M.2    McIntyre, T.M.3
  • 49
    • 18244373708 scopus 로고    scopus 로고
    • Role of lipoprotein-associated phospholipase A 2 in atherosclerosis: Biology, epidemiology, and possible therapeutic target
    • Zalewski A. & Macphee C. Role of lipoprotein-associated phospholipase A 2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arterioscler. Thromb. Vasc. Biol. 25, 923-931 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 923-931
    • Zalewski, A.1    Macphee, C.2
  • 50
    • 84864829781 scopus 로고    scopus 로고
    • Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2
    • Rosenson R. S. Stafforini D. M.Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2 J. Lipid Res.53 1767-1782 2012).
    • (2012) J. Lipid Res , vol.53 , pp. 1767-1782
    • Rosenson, R.S.1    Stafforini, D.M.2
  • 51
    • 84861631409 scopus 로고    scopus 로고
    • L ipoprotein-associated phospholipase A2 (Lp-PLA2): A review of its role and significance as a cardiovascular biomarker
    • Vittos O., Toana B., Vittos A. & Moldoveanu E. L ipoprotein-associated phospholipase A2 (Lp-PLA2): a review of its role and significance as a cardiovascular biomarker. Biomarkers 17, 289-302 (2012).
    • (2012) Biomarkers , vol.17 , pp. 289-302
    • Vittos, O.1    Toana, B.2    Vittos, A.3    Moldoveanu, E.4
  • 52
    • 67049172713 scopus 로고    scopus 로고
    • Lipoprotei n-associated phospholipase A2: A cardiovascular risk predictor and a potential therapeutic target
    • Ali M. & Madjid M. Lipoprotei n-associated phospholipase A2: a cardiovascular risk predictor and a potential therapeutic target. Future Cardiol. 5, 159-173 (2009).
    • (2009) Future Cardiol , vol.5 , pp. 159-173
    • Ali, M.1    Madjid, M.2
  • 53
    • 33747860581 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2
    • McConnell J. P. & Hoefner D. M. Lipoprotein-associated phospholipase A2. Clin. Lab. Med. 26, 679-697 (2006).
    • (2006) Clin. Lab. Med , vol.26 , pp. 679-697
    • McConnell, J.P.1    Hoefner, D.M.2
  • 54
    • 78650161683 scopus 로고    scopus 로고
    • Lipoprotein-associated and secreted phospholipases A(2) in cardiovascular disease: Roles as bio logical effectors and biomarkers
    • Mallat Z., Lambeau G. & Tedgui A. Lipoprotein-associated and secreted phospholipases A(2) in cardiovascular disease: roles as bio logical effectors and biomarkers. Circulation 122, 2183-2200(2010).
    • (2010) Circulation , vol.122 , pp. 2183-2200
    • Mallat, Z.1    Lambeau, G.2    Tedgui, A.3
  • 55
    • 43049122963 scopus 로고    scopus 로고
    • The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: The res ults of a multicenter, randomized, double-blind, placebo-controlled study
    • Mohler E. R. III et al. The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the res ults of a multicenter, randomized, double-blind, placebo-controlled study. J. Am. Coll. Cardiol. 51, 1632-1641 (2008).
    • (2008) J. Am. Coll. Cardiol , vol.51 , pp. 1632-1641
    • Mohler, E.R.1
  • 56
    • 84899718423 scopus 로고    scopus 로고
    • Darapladib for preventing ischemic events in stable coronary heart disease
    • White H. D. et al. Darapladib for preventing ischemic events in stable coronary heart disease. N. Engl. J. Med. 370, 1702-1711 (2014).
    • (2014) N. Engl. J. Med , vol.370 , pp. 1702-1711
    • White, H.D.1
  • 57
    • 84884302135 scopus 로고    scopus 로고
    • Translation of high-density lipoprotein function into clinical practice: Current prospects and future challenges
    • Rosenson R. S. et al. Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges. Circulation 128, 1256-1267 (2013).
    • (2013) Circulation , vol.128 , pp. 1256-1267
    • Rosenson, R.S.1
  • 58
    • 43449085800 scopus 로고    scopus 로고
    • Laboratory assessment of HDL heterogeneity and function
    • Movva R. & Rader D. J. Laboratory assessment of HDL heterogeneity and function. Clin. Chem. 54, 788-800 (2008).
    • (2008) Clin. Chem , vol.54 , pp. 788-800
    • Movva, R.1    Rader, D.J.2
  • 59
    • 34047106220 scopus 로고    scopus 로고
    • Effect of torcetrapib on the progression of coronary atherosclerosis
    • Nissen S. E. et al. Effect of torcetrapib on the progression of coronary atherosclerosis. N. Engl. J. Med. 356, 1304-1316 (2007).
    • (2007) N. Engl. J. Med , vol.356 , pp. 1304-1316
    • Nissen, S.E.1
  • 60
    • 36348975228 scopus 로고    scopus 로고
    • Effects of to rcetrapib in patients at high risk for coronary events
    • Barter P. J. et al. Effects of to rcetrapib in patients at high risk for coronary events. N. Engl. J. Med. 357, 2109-2122 (2007).
    • (2007) N. Engl. J. Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1
  • 61
    • 79953867783 scopus 로고    scopus 로고
    • Association between change in high density lipoprotein cholesterol and cardiovascula r disease morbidity and mortality: Systematic review and meta-regression analysis
    • Briel M. et al. Association between change in high density lipoprotein cholesterol and cardiovascula r disease morbidity and mortality: systematic review and meta-regression analysis. BMJ 338, b92 (2009).
    • (2009) BMJ , vol.338 , pp. b92
    • Briel, M.1
  • 62
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R. et al. A common allele on chromosome 9 associated with coronary heart disease. Science 316, 1488-1491 (2007).
    • (2007) Science , vol.316 , pp. 1488-1491
    • McPherson, R.1
  • 63
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • Willer C. J. et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat. Genet. 40, 161-169 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 161-169
    • Willer, C.J.1
  • 64
    • 58149161560 scopus 로고    scopus 로고
    • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
    • Aulchenko Y. S. et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat. Genet. 41, 47-55 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 47-55
    • Aulchenko, Y.S.1
  • 65
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
    • Voight B. F. et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet 380, 572-580 (2012).
    • (2012) Lancet , vol.380 , pp. 572-580
    • Voight, B.F.1
  • 66
    • 39449100874 scopus 로고    scopus 로고
    • Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity
    • de Souza J. A. et al. Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity. Atherosclerosis 197, 84-94 (2008).
    • (2008) Atherosclerosis , vol.197 , pp. 84-94
    • De Souza, J.A.1
  • 67
    • 70249083443 scopus 로고    scopus 로고
    • Impaired protection against diabetes and coronary heart disease by high-density lipoproteins in Turks
    • Onat A., Can. G., Ayhan E., Kaya Z. & Hergenc G. Impaired protection against diabetes and coronary heart disease by high-density lipoproteins in Turks. Metabolism 58, 1393-1399 (2009).
    • (2009) Metabolism , vol.58 , pp. 1393-1399
    • Onat, A.1    Can, G.2    Ayhan, E.3    Kaya, Z.4    Hergenc, G.5
  • 68
    • 84904246685 scopus 로고    scopus 로고
    • Coronary heart disease risks associated with high levels of HDL cholesterol
    • Wilkins J. T. et al. Coronary heart disease risks associated with high levels of HDL cholesterol. J. Am. Heart Assoc. 3, e000519 (2014).
    • (2014) J. Am. Heart Assoc , vol.3 , pp. e000519
    • Wilkins, J.T.1
  • 69
    • 78651379500 scopus 로고    scopus 로고
    • Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
    • Khera A. V. et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N. Engl. J. Med. 364, 127-135 (2011).
    • (2011) N. Engl. J. Med , vol.364 , pp. 127-135
    • Khera, A.V.1
  • 70
    • 84879113852 scopus 로고    scopus 로고
    • Parado xical association of enhanced cholesterol efflux with increased incident cardiovascular risks
    • Li X. M. et al. Parado xical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler. Thromb. Vasc. Biol. 33, 1696-1705 (2013).
    • (2013) Arterioscler. Thromb. Vasc. Biol , vol.33 , pp. 1696-1705
    • Li, X.M.1
  • 71
    • 8344241096 scopus 로고    scopus 로고
    • High-density lip oprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study
    • Asztalos B. F. et al High-density lip oprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study. Arterioscler. Thromb. Vasc. Biol. 24 2181-2187 2004).
    • (2004) Arterioscler. Thromb. Vasc. Biol , vol.24 , pp. 2181-2187
    • Asztalos, B.F.1
  • 72
    • 61849110301 scopus 로고    scopus 로고
    • Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women
    • Mora S. et al. Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women. Circulation 119, 931-939 (2009).
    • (2009) Circulation , vol.119 , pp. 931-939
    • Mora, S.1
  • 73
    • 85027944383 scopus 로고    scopus 로고
    • Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study
    • Pa rish S. et al. Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study. Circulation 125, 2469-2478 (2012).
    • (2012) Circulation , vol.125 , pp. 2469-2478
    • Pa Rish, S.1
  • 74
    • 0026091744 scopus 로고
    • A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction
    • Stampfer M. J., Sacks, F. M. , Salvini S., Willett W. C. & Hennekens C. H. A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N. Engl. J. Med. 325, 373-381 (1991).
    • (1991) N. Engl. J. Med , vol.325 , pp. 373-381
    • Stampfer, M.J.1    Sacks, F.M.2    Salvini, S.3    Willett, W.C.4    Hennekens, C.H.5
  • 75
    • 78650851475 scopus 로고    scopus 로고
    • Prospective study of coronary heart disease vs. HDL2, HDL3, and other lipoproteins in Gofman's Livermore Cohort
    • Willia ms P. T. & Feldman D. E. Prospective study of coronary heart disease vs. HDL2, HDL3, and other lipoproteins in Gofman's Livermore Cohort. Atherosclerosis 214, 196-202 (2011).
    • (2011) Atherosclerosis , vol.214 , pp. 196-202
    • Willia Ms, P.T.1    Feldman, D.E.2
  • 76
    • 38749102779 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: Significance for cardiovascular risk: The IDEAL and EPIC-Norfolk studies
    • van der Steeg W. A. et al. High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies. J. Am. Coll.Cardiol. 51, 634-642 (2008).
    • (2008) J. Am. Coll.Cardiol , vol.51 , pp. 634-642
    • Van Der Steeg, W.A.1
  • 77
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • Schwartz G. G. et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N. Engl. J. Med. 367, 2089-2099 (2012).
    • (2012) N. Engl. J. Med , vol.367 , pp. 2089-2099
    • Schwartz, G.G.1
  • 78
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins H. B. e t al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N. Engl. J. Med. 341, 410-418 (1999).
    • (1999) N. Engl. J. Med , vol.341 , pp. 410-418
    • Rubins, H.B.1
  • 79
    • 26244436291 scopus 로고    scopus 로고
    • Value of high-density lipoprotein (HDL) subpopulations in predicting recurrent cardiovascular events in the Veterans Affairs HDL Intervention Trial
    • Asztalos B. F. et al. Value of high-density lipoprotein (HDL) subpopulations in predicting recurrent cardiovascular events in the Veterans Affairs HDL Intervention Trial. Arterioscler. T hromb. Vasc. Biol. 25, 2185-2191 (2005).
    • (2005) Arterioscler. T Hromb. Vasc. Biol , vol.25 , pp. 2185-2191
    • Asztalos, B.F.1
  • 80
    • 36849023953 scopus 로고    scopus 로고
    • Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affai rs High-Density Lipoprotein Intervention Trial
    • Asztalos B. F. et al. Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affai rs High-Density Lipoprotein Intervention Trial. Metabolism 57, 77-83 (2008).
    • (2008) Metabolism , vol.57 , pp. 77-83
    • Asztalos, B.F.1
  • 81
    • 0029589645 scopus 로고    scopus 로고
    • Significance of apolipoproteins for structure, function, and classification of plasma lipoproteins
    • Alaupovic P. Significance of apolipoproteins for structure, function, and classification of plasma lipoproteins. Methods Enzymol. 263, 32-60 (1996).
    • (1996) Methods Enzymol , vol.263 , pp. 32-60
    • Alaupovic, P.1
  • 82
    • 84884138140 scopus 로고    scopus 로고
    • Proteomic diversity of high density lipoproteins: Our emerging understanding of its importance in lipid transport and beyond
    • Shah A. S., Tan L., Long J. L. & Davidson W. S. Proteomic diversity of high density lipoproteins: our emerging understanding of its importance in lipid transport and beyond. J. Lipid Res. 54, 2575-2585 (2013).
    • (2013) J. Lipid Res , vol.54 , pp. 2575-2585
    • Shah, A.S.1    Tan, L.2    Long, J.L.3    Davidson, W.S.4
  • 83
    • 84893772037 scopus 로고    scopus 로고
    • An abundant dysfunctional apolipoprotein A1 in human atheroma
    • Huang Y. et al. An abundant dysfunctional apolipoprotein A1 in human atheroma. Nat. Med. 20, 193-203 (2014).
    • (2014) Nat. Med , vol.20 , pp. 193-203
    • Huang, Y.1
  • 84
    • 84870387945 scopus 로고    scopus 로고
    • Apolipoprotein C-III as a potential modulator of the association between HDL-cholesterol and incident coronary heart d isease
    • Jensen M. K., Rimm E. B., Furtado J. D. & Sacks, F. M. Apolipoprotein C-III as a potential modulator of the association between HDL-cholesterol and incident coronary heart d isease. J. Am. Heart Assoc. 1, jah3-e000232 (2012).
    • (2012) J. Am. Heart Assoc , vol.1 , pp. jah3-e000232
    • Jensen, M.K.1    Rimm, E.B.2    Furtado, J.D.3    Sacks, F.M.4
  • 85
    • 80855152977 scopus 로고    scopus 로고
    • Low-density lipoproteins containing apolipoprotein C-III and the risk of coronary heart disease
    • Mendivil C. O., Rimm E. B., Furtado J., Chiuve S. E. & Sacks, F. M. Low-density lipoproteins containing apolipoprotein C-III and the risk of coronary heart disease. Circulation 124, 2065-2072 (2011).
    • (2011) Circulation , vol.124 , pp. 2065-2072
    • Mendivil, C.O.1    Rimm, E.B.2    Furtado, J.3    Chiuve, S.E.4    Sacks, F.M.5
  • 86
    • 85028115787 scopus 로고    scopus 로고
    • Presence of apolipoprotein C-III defines a high density lipoprotein subtype that is not inversely associated with incident coronary events [abstract 023
    • Jensen M. K., Furtado J. D., Rimm E. B., Sacks, F. M. & Overvad K. Presence of apolipoprotein C-III defines a high density lipoprotein subtype that is not inversely associated with incident coronary events [abstract 023]. Circulation 127 (Suppl. 12), A023 (2013).
    • (2013) Circulation , vol.127 , pp. A023
    • Jensen, M.K.1    Furtado, J.D.2    Rimm, E.B.3    Sacks, F.M.4    Overvad, K.5
  • 87
    • 33644866843 scopus 로고    scopus 로고
    • Apolip oprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells
    • Kawakami A. et al. Apolip oprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells. Circulation 113, 691-700 (2006).
    • (2006) Circulation , vol.113 , pp. 691-700
    • Kawakami, A.1
  • 88
    • 84878637167 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans
    • Graham M. J. et al. Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans. Circ. Res. 112, 1479-1490 (2013).
    • (2013) Circ. Res , vol.112 , pp. 1479-1490
    • Graham, M.J.1
  • 89
    • 3142680190 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Biological mechanisms, observational epidemiology, and the need for randomized trials
    • Splaver A., Lamas G. A. & Henneken s C. H. Homocysteine and cardiovascular disease: biological mechanisms, observational epidemiology, and the need for randomized trials. Am. Heart J. 148, 34-40 (2004).
    • (2004) Am. Heart J , vol.148 , pp. 34-40
    • Splaver, A.1    Lamas, G.A.2    Henneken, S.C.H.3
  • 90
    • 0014545138 scopus 로고
    • Vascular patholog y of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
    • McCully K. S. Vascular patholog y of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am. J. Pathol. 56, 111-128 (1969).
    • (1969) Am. J. Pathol , vol.56 , pp. 111-128
    • McCully, K.S.1
  • 91
    • 0029066299 scopus 로고
    • A quanti tative assessment of plasma homocysteine as a risk factor for vascular disease Probable benefits of increasing folic acid intakes
    • Boushey C. J., Beresford S. A., Omenn G. S. & Motulsky A. G. A quanti tative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274, 1049-1057 (1995).
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 92
    • 33645743547 scopus 로고    scopus 로고
    • Improvement in stroke mortality in Canada and the United States 1990 to 2002
    • Yang Q. et al. Improvement in stroke mortality in Canada and the United States 1990 to 2002. Circulation 113 1335-1343 2006).
    • (2006) Circulation , vol.113 , pp. 1335-1343
    • Yang, Q.1
  • 94
    • 77957949167 scopus 로고    scopus 로고
    • Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mo rtality: Meta-analysis of 8 randomized trials involving 37,485 individuals
    • Clarke R. et al. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mo rtality: Meta-analysis of 8 randomized trials involving 37,485 individuals. Arch. Intern. Med. 170, 1622-1631 (2010).
    • (2010) Arch. Intern. Med , vol.170 , pp. 1622-1631
    • Clarke, R.1
  • 95
    • 34249730020 scopus 로고    scopus 로고
    • Eff icacy of folic acid supplementation in stroke prevention: A meta-analysis
    • Wang X. et al. Eff icacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet 369, 1876-1882 (2007).
    • (2007) Lancet , vol.369 , pp. 1876-1882
    • Wang, X.1
  • 96
    • 65249094749 scopus 로고    scopus 로고
    • Homocyst eine-lowering therapy and stroke risk, severity, and disability: Additional findings from the HOPE 2 trial
    • Saposnik G., Ray J. G., Sheridan P., McQueen M. & Lonn E. Homocyst eine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial. Stroke 40, 1365-1372 (2009).
    • (2009) Stroke , vol.40 , pp. 1365-1372
    • Saposnik, G.1    Ray, J.G.2    Sheridan, P.3    McQueen, M.4    Lonn, E.5
  • 97
    • 77950359814 scopus 로고    scopus 로고
    • Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events
    • Wang L., Manson J. E., Song Y. & Sesso H. D. Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann. Intern. Med. 152, 315-323 (2010).
    • (2010) Ann. Intern. Med , vol.152 , Issue.315-323
    • Wang, L.1    Manson, J.E.2    Song, Y.3    Sesso, H.D.4
  • 98
    • 1642281100 scopus 로고    scopus 로고
    • Vitamin D: Importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis
    • Holick M. F. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am. J. Clin. Nutr. 79, 362-371 (2004).
    • (2004) Am. J. Clin. Nutr , vol.79 , pp. 362-371
    • Holick, M.F.1
  • 99
    • 0022489985 scopus 로고
    • Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein
    • Bikle D. D. et al. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J. Clin. Endocrinol. Metab. 63, 954-959 (1986).
    • (1986) J. Clin. Endocrinol. Metab , vol.63 , pp. 954-959
    • Bikle, D.D.1
  • 100
    • 0022388403 scopus 로고
    • Serum protein binding of 1,25-dihydroxyvitamin D: A reevaluation by direct measurement of free metabolite levels
    • Bikle D. D., Siiteri P. K., Ryzen E. & Haddad J. G. Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J. Clin. Endocrinol. Metab. 61, 969-975 (1985).
    • (1985) J. Clin. Endocrinol. Metab , vol.61 , pp. 969-975
    • Bikle, D.D.1    Siiteri, P.K.2    Ryzen, E.3    Haddad, J.G.4
  • 101
    • 74449090261 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D3) is an agonistic vitamin D receptor ligand
    • Lou Y.R. et al. 25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand. J. Steroid Biochem. Mol. Biol. 118, 162-170 (2010).
    • (2010) J. Steroid Biochem. Mol. Biol , vol.118 , pp. 162-170
    • Lou, Y.R.1
  • 102
    • 46449131684 scopus 로고    scopus 로고
    • Independent associa tion of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all-cause and cardiovascular mortality
    • Dobnig H. et al. Independent associa tion of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all-cause and cardiovascular mortality. Arch. Intern. Med. 168, 1340-1349 (2008).
    • (2008) Arch. Intern. Med , vol.168 , pp. 1340-1349
    • Dobnig, H.1
  • 103
    • 33744820613 scopus 로고    scopus 로고
    • Vitamin D and disease prevention with special reference to cardiovascular disease
    • Zittermann A. Vitamin D and disease prevention with special reference to cardiovascular disease. Prog. Biophys. Mol. Biol. 92, 39-48 (2006).
    • (2006) Prog. Biophys. Mol. Biol , vol.92 , pp. 39-48
    • Zittermann, A.1
  • 104
    • 0036186116 scopus 로고    scopus 로고
    • Synthesis of 1,25-dihydroxyvitamin D3 by human endothelial cells is regulat ed by inflammatory cytokines: A novel autocrine determinant of vascular cell adhesion
    • Zehnder D. et al. Synthesis of 1,25-dihydroxyvitamin D3 by human endothelial cells is regulat ed by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. J. Am. Soc. Nephrol. 13, 621-629 (2002).
    • (2002) J. Am. Soc. Nephrol , vol.13 , pp. 621-629
    • Zehnder, D.1
  • 105
    • 84871877598 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D levels and risk of ischemic heart disease, myocardial infarction, and early death: Population-based study and meta-analyses of 18 and 17 studies
    • Brø ndum-Jacobsen P., Benn M., Jensen G. B. & Nordestgaard B. G. 25-hydroxyvitamin D levels and risk of ischemic heart disease, myocardial infarction, and early death: population-based study and meta-analyses of 18 and 17 studies. Arterioscler. Thromb. Vasc. Biol. 32, 2794-2802 (2012).
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 2794-2802
    • Brø Ndum-Jacobsen, P.1    Benn, M.2    Jensen, G.B.3    Nordestgaard, B.G.4
  • 106
    • 79959220177 scopus 로고    scopus 로고
    • Vitamin D status and risk of cardiovascular events: Lessons learned via systematic review and meta-analysis
    • Sokol S. I., Tsang P., Aggarwal V., Melamed M. L. & Srinivas V. S. Vitamin D status and risk of cardiovascular events: lessons learned via systematic review and meta-analysis. Cardiol. Rev. 19, 192-201 (2011).
    • (2011) Cardiol. Rev , vol.19 , Issue.192-201
    • Sokol, S.I.1    Tsang, P.2    Aggarwal, V.3    Melamed, M.L.4    Srinivas, V.S.5
  • 107
    • 84873643365 scopus 로고    scopus 로고
    • Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: A meta-analysis of prospective studies
    • Wang L. et al. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies. Circ. Cardiovasc. Qual. Outcomes 5, 819-829 (2012).
    • (2012) Circ. Cardiovasc. Qual. Outcomes , vol.5 , pp. 819-829
    • Wang, L.1
  • 108
    • 79955479060 scopus 로고    scopus 로고
    • Vitamin D and cardiovascular disease: Systematic review and meta-analysis of prospective studies
    • Grandi N. C., Breitling L. P. & Brenner H. Vitamin D and cardiovascular disease: systematic review and meta-analysis of prospective studies. Prev. Med. 51, 228-233 (2010).
    • (2010) Prev. Med , vol.51 , pp. 228-233
    • Grandi, N.C.1    Breitling, L.P.2    Brenner, H.3
  • 109
    • 34247893803 scopus 로고    scopus 로고
    • Plasma 25-hydroxyvitamin D levels and risk of incident hypertension
    • Forman J. P. et al. Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension 49, 1063-1069 (2007).
    • (2007) Hypertension , vol.49 , pp. 1063-1069
    • Forman, J.P.1
  • 110
    • 35148824474 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes
    • Mattil a C. et al. Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care 30, 2569-2570 (2007).
    • (2007) Diabetes Care , vol.30 , pp. 2569-2570
    • Mattil, A.C.1
  • 111
    • 38849189427 scopus 로고    scopus 로고
    • Vitamin K and vitamin D status: Associations with inflammatory markers in the Framingham Offspring Study
    • Shea M. K. et al. Vitamin K and vitamin D status: associations with inflammatory markers in the Framingham Offspring Study. Am. J. Epidemiol. 167, 313-320(2008).
    • (2008) Am. J. Epidemiol , vol.167 , pp. 313-320
    • Shea, M.K.1
  • 112
    • 84877711545 scopus 로고    scopus 로고
    • Vitamin D and risk of death from vascular and non-vascular causes in the Whitehall study and meta-analyses of 12,000 deaths
    • Tomson J. e t al. Vitamin D and risk of death from vascular and non-vascular causes in the Whitehall study and meta-analyses of 12,000 deaths. Eur. Heart J. 34, 1365-1374 (2013).
    • (2013) Eur. Heart J , vol.34 , pp. 1365-1374
    • Tomson, J.1
  • 113
    • 0037987940 scopus 로고    scopus 로고
    • Higher impact of mineral metabolism on cardiovascular mortality in a European hemodialysis population
    • Marco M. P. et al. Higher impact of mineral metabolism on cardiovascular mortality in a European hemodialysis population. Kidney Int. Suppl. 85, S111-S114 (2003).
    • (2003) Kidney Int. Suppl , vol.85 , pp. S111-S114
    • Marco, M.P.1
  • 114
    • 53049103995 scopus 로고    scopus 로고
    • Oral active vitamin D is associated with improved survival in hemodialysis patients
    • Naves-Diaz M. et al.i Oral active vitamin D is associated with improved survival in hemodialysis patients Kidney Int. 74 1070-1078 2008).
    • (2008) Kidney Int , vol.74 , pp. 1070-1078
    • Naves-Diaz, M.1
  • 115
    • 9144265456 scopus 로고    scopus 로고
    • Lower risk for cardiovascular mortality in oral 1'-hydroxy vitamin D3 users in a haemodialysis population
    • Shoji T. et al. Lower risk for cardiovascular mortality in oral 1'-hydroxy vitamin D3 users in a haemodialysis population. Nephrol. Dial. Transplant. 19, 179-184 (2004).
    • (2004) Nephrol. Dial. Transplant , vol.19 , pp. 179-184
    • Shoji, T.1
  • 116
    • 20844459261 scopus 로고    scopus 로고
    • Activated injectable vitamin D and hemodialysis survival: A historical cohort study
    • Teng M. et al. Activated injectable vitamin D and hemodialysis survival: a historical cohort study. J. Am. Soc. Nephrol. 16, 1115-1125 (2005).
    • (2005) J. Am. Soc. Nephrol , vol.16 , pp. 1115-1125
    • Teng, M.1
  • 117
    • 34948869354 scopus 로고    scopus 로고
    • Vitamin D levels and early mortality among incident hemodialysis patients
    • Wolf M. et al. Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int. 72, 1004-1013 (2007).
    • (2007) Kidney Int , vol.72 , pp. 1004-1013
    • Wolf, M.1
  • 118
    • 33847110738 scopus 로고    scopus 로고
    • Calcium/vitamin D supplementation and cardiovascular events
    • Hsia J. et al. Calcium/vitamin D supplementation and cardiovascular events. Circulation 115, 846-854 (2007).
    • (2007) Circulation , vol.115 , pp. 846-854
    • Hsia, J.1
  • 119
    • 84875171399 scopus 로고    scopus 로고
    • Effect of vitamin D supplementation on blood pressure in blacks
    • Forman J. P. et al. Effect of vitamin D supplementation on blood pressure in blacks. Hypertension. 61, 779-785 (2013).
    • (2013) Hypertension , vol.61 , pp. 779-785
    • Forman, J.P.1
  • 120
    • 2142746439 scopus 로고    scopus 로고
    • FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis
    • Shimada T. et al. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J. Bone. Miner. Res. 19, 429-435 (2004).
    • (2004) J. Bone. Miner. Res , vol.19 , pp. 429-435
    • Shimada, T.1
  • 121
    • 66349097180 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease
    • Gutierrez O. M. et al. Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. Circulation 119, 2545-2552 (2009).
    • (2009) Circulation , vol.119 , pp. 2545-2552
    • Gutierrez, O.M.1
  • 122
    • 49249104701 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
    • Gutierrez O. M. et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N. Engl. J. Med. 359, 584-592 (2008).
    • (2008) N. Engl. J. Med , vol.359 , pp. 584-592
    • Gutierrez, O.M.1
  • 123
    • 79958724181 scopus 로고    scopus 로고
    • Fibrobla st growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
    • Isakova T. et al. Fibrobla st growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA 305, 2432-2439 (2011).
    • (2011) JAMA , vol.305 , pp. 2432-2439
    • Isakova, T.1
  • 124
    • 70450230670 scopus 로고    scopus 로고
    • Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
    • Mirza M. A., Larsson A., Melhus H., Li nd L. & Larsson T. E. Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population. Atherosclerosis 207, 546-551 (2009).
    • (2009) Atherosclerosis , vol.207 , pp. 546-551
    • Mirza, M.A.1    Larsson, A.2    Melhus, H.3    Li Nd, L.4    Larsson, T.E.5
  • 125
    • 77952996999 scopus 로고    scopus 로고
    • The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: The Heart and Soul Study
    • Parker B. D. et al. The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study. Ann. Intern. Med. 152, 640-648 (2010).
    • (2010) Ann. Intern. Med , vol.152 , pp. 640-648
    • Parker, B.D.1
  • 126
    • 80755172594 scopus 로고    scopus 로고
    • The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation
    • Seiler S. et al. The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation. Eur. Heart J. 32, 2688-2696 (2011).
    • (2011) Eur. Heart J , vol.32 , pp. 2688-2696
    • Seiler, S.1
  • 127
    • 80555148939 scopus 로고    scopus 로고
    • FGF23 induces left ventricular hypertrophy
    • Faul C. et al. FGF23 induces left ventricular hypertrophy. J. Clin. Invest. 121, 4393-4408 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 4393-4408
    • Faul, C.1
  • 128
    • 84863550146 scopus 로고    scopus 로고
    • FGF23 neutrali zation improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
    • Shalhoub V. et al. FGF23 neutrali zation improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J. Clin. Invest. 122, 2543-2553 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 2543-2553
    • Shalhoub, V.1
  • 129
    • 84878487994 scopus 로고    scopus 로고
    • FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy
    • Touchberry C. D. et al. FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy. Am. J. Physiol. Endocrinol. Metab. 304, E863-E873 (2013).
    • (2013) Am. J. Physiol. Endocrinol. Metab , vol.304 , pp. E863-E873
    • Touchberry, C.D.1
  • 130
    • 84875729670 scopus 로고    scopus 로고
    • Fractional excretion of phosphorus modifies the association between fibroblast growth factor-23 and outcomes
    • Dominguez J. R., Shlipak M. G., Whooley M. A. & Ix J. H. Fractional excretion of phosphorus modifies the association between fibroblast growth factor-23 and outcomes. J. Am. Soc. Nephrol. 24, 647-654 (2013).
    • (2013) J. Am. Soc. Nephrol , vol.24 , pp. 647-654
    • Dominguez, J.R.1    Shlipak, M.G.2    Whooley, M.A.3    Ix, J.H.4
  • 132
    • 0036750241 scopus 로고    scopus 로고
    • Adiponectin-its role in metabolism and beyond
    • Stefan N. & Stumvoll M. Adiponectin-its role in metabolism and beyond. Horm. Metab. Res. 34, 469-474 (2002).
    • (2002) Horm. Metab. Res , vol.34 , pp. 469-474
    • Stefan, N.1    Stumvoll, M.2
  • 133
    • 67650169799 scopus 로고    scopus 로고
    • Adiponectin levels and risk of type 2 diabetes: A systematic review and meta-analysis
    • Li S., Shin H. J., Ding E. L. & van Dam R. M. Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. JAMA 302, 179-188 (2009).
    • (2009) JAMA , vol.302 , pp. 179-188
    • Li, S.1    Shin, H.J.2    Ding, E.L.3    Van Dam, R.M.4
  • 134
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K. et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50, 1126-1133 (2001).
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1
  • 135
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocy te-derived macrophages
    • Ouchi N. et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocy te-derived macrophages Circulation 103 1057-1063 2001).
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1
  • 136
    • 1842864234 scopus 로고    scopus 로고
    • Plasma adiponectin levels and risk of myocardial infarction in men
    • Pischon T. et al. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 291, 1730-1737 (2004).
    • (2004) JAMA , vol.291 , pp. 1730-1737
    • Pischon, T.1
  • 137
    • 33746745255 scopus 로고    scopus 로고
    • Adiponectin and coronary heart disease: A prospective study and meta-analysis
    • Sattar N. et al. Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation 114, 623-629 (2006).
    • (2006) Circulation , vol.114 , pp. 623-629
    • Sattar, N.1
  • 138
    • 26244462007 scopus 로고    scopus 로고
    • Adiponectin and coronary heart disease: The Strong Heart Study
    • Lindsay R. S. et al. Adiponectin and coronary heart disease: the Strong Heart Study. Arterioscler. Thromb. Vasc. Biol. 25, e15-e16 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. e15-e16
    • Lindsay, R.S.1
  • 139
    • 51049123168 scopus 로고    scopus 로고
    • Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women
    • Heidemann C. et al. Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann. Intern. Med. 149, 307-316 (2008).
    • (2008) Ann. Intern. Med , vol.149 , pp. 307-316
    • Heidemann, C.1
  • 140
    • 80055012490 scopus 로고    scopus 로고
    • Plasma total and high molecular weight adiponectin levels and risk of coronary heart disease in women
    • Pischon T. et al. Plasma total and high molecular weight adiponectin levels and risk of coronary heart disease in women. Atherosclerosis 219, 322-329 (2011).
    • (2011) Atherosclerosis , vol.219 , pp. 322-329
    • Pischon, T.1
  • 141
    • 84872060008 scopus 로고    scopus 로고
    • Total and high-molecular-weight adiponectin and risk of coronary heart disease and ischemic stroke in older adults
    • Kizer J. R. et al. Total and high-molecular-weight adiponectin and risk of coronary heart disease and ischemic stroke in older adults. J. Clin. Endocrinol. Metab. 98, 255-263 (2013).
    • (2013) J. Clin. Endocrinol. Metab , vol.98 , pp. 255-263
    • Kizer, J.R.1
  • 142
    • 33947588150 scopus 로고    scopus 로고
    • Adipo nectin and cardiovascular mortality: Evidence for " reverse epidemiology"
    • Rathmann W. & Herder C. Adipo nectin and cardiovascular mortality: evidence for " reverse epidemiology" . Horm. Metab. Res. 39, 1-2 (2007).
    • (2007) Horm. Metab. Res , vol.39 , pp. 1-2
    • Rathmann, W.1    Herder, C.2
  • 143
    • 79958111379 scopus 로고    scopus 로고
    • Assessment of adiponectin and the risk of recurrent cardi ovascular events in patients presenting with an acute coronary syndrome: Observations from the Pravastatin or atorVastatin Evaluation and Infection Trial-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22
    • Wilson S. R. et al. Assessment of adiponectin and the risk of recurrent cardi ovascular events in patients presenting with an acute coronary syndrome: observations from the Pravastatin Or atorVastatin Evaluation and Infection Trial-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22). Am. Heart J. 161, 1147-1155 (2011).
    • (2011) Am. Heart J , vol.161 , pp. 1147-1155
    • Wilson, S.R.1
  • 144
    • 60849138823 scopus 로고    scopus 로고
    • Serum adiponectin confers little protection against diabetes and hypertension in Turkish men
    • Onat A., Hergenc G., Can. G. & Kucukdurmaz Z. Serum adiponectin confers little protection against diabetes and hypertension in Turkish men. Obesity (Silver Spring) 17, 564-570 (2009).
    • (2009) Obesity (Silver Spring , vol.17 , pp. 564-570
    • Onat, A.1    Hergenc Can. G, G.2    Kucukdurmaz, Z.3
  • 145
    • 0036307162 scopus 로고    scopus 로고
    • A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome
    • Menzaghi C. et al. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 51, 2306-2312 (2002).
    • (2002) Diabetes , vol.51 , pp. 2306-2312
    • Menzaghi, C.1
  • 146
    • 85028128278 scopus 로고    scopus 로고
    • ADIPOGen Consortium [online
    • ADIPOGen Consortium [online], http://www.mcgill.ca/genepi/adipogen-consortium (2014).
    • (2014)
  • 147
    • 85028093572 scopus 로고    scopus 로고
    • CARDIoGRAMplusC4D Consortium [online
    • CARDIoGRAMplusC4D Consortium [online], http://www.cardiogramplusc4d.org (2013).
    • (2013)
  • 148
    • 84879415419 scopus 로고    scopus 로고
    • The shared allelic architecture of adiponectin levels and coronary artery disease
    • Dastani Z. et al. The shared allelic architecture of adiponectin levels and coronary artery disease. Atherosclerosis 229, 145-148 (2013).
    • (2013) Atherosclerosis , vol.229 , Issue.145-148
    • Dastani, Z.1
  • 149
    • 14344273991 scopus 로고    scopus 로고
    • Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome
    • Ki ssebah A. H. et al. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc. Natl Acad. Sci. USA 97, 14478-14483 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 14478-14483
    • Ki Ssebah, A.H.1
  • 150
    • 84859238629 scopus 로고    scopus 로고
    • N ovel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals
    • Dastani Z. et al. N ovel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 8, e1002607 (2012).
    • (2012) PLoS Genet , vol.8 , pp. e1002607
    • Dastani, Z.1
  • 151
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T. et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 1784-1792
    • Kadowaki, T.1
  • 152
    • 67349122316 scopus 로고    scopus 로고
    • Effect of weight loss on coronary circulation and adiponectin levels in obese women
    • Coppola A. et al. Effect of weight loss on coronary circulation and adiponectin levels in obese women. Int. J. Cardiol. 134, 414-416 (2009).
    • (2009) Int. J. Cardiol , vol.134 , pp. 414-416
    • Coppola, A.1
  • 153
    • 77952772989 scopus 로고    scopus 로고
    • Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults
    • Selvin E. et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N. Engl. J. Med. 362, 800-811 (2010).
    • (2010) N. Engl. J. Med , vol.362 , Issue.800-811
    • Selvin, E.1
  • 154
    • 25144514392 scopus 로고    scopus 로고
    • Glycemic control and coronary heart disease risk in persons with and without diabetes: The atherosclerosis risk in communities study
    • Selvin E. et al. Glycemic control and coronary heart disease risk in persons with and without diabetes: the atherosclerosis risk in communities study. Arch. Intern. Med. 165, 1910-1916 (2005).
    • (2005) Arch. Intern. Med , vol.165 , pp. 1910-1916
    • Selvin, E.1
  • 155
    • 34547446716 scopus 로고    scopus 로고
    • Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women
    • Pradhan A. D., Rifai N., Buring J. E. & Ridker P. M. Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women. Am. J. Med. 120, 720-727 (2007).
    • (2007) Am. J. Med , vol.120 , pp. 720-727
    • Pradhan, A.D.1    Rifai, N.2    Buring, J.E.3    Ridker, P.M.4
  • 156
    • 4644336398 scopus 로고    scopus 로고
    • Association of hemoglobin A1c with cardiovascular disease and mortality in adults: The European prospective investigation into cancer in Norfolk
    • Khaw K. T. et al Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk. Ann. Intern. Med.141 413-4202004).
    • (2004) Ann. Intern. Med , vol.141 , pp. 413-420
    • Khaw, K.T.1
  • 157
    • 60849120429 scopus 로고    scopus 로고
    • Independent association of HbA1c and incident cardiovascular disease in people without diabetes
    • Adams R. J. et al. Independent association of HbA1c and incident cardiovascular disease in people without diabetes. Obesity (Silver Spring) 17, 559-563 (2009).
    • (2009) Obesity (Silver Spring , vol.17 , pp. 559-563
    • Adams, R.J.1
  • 158
    • 34548459499 scopus 로고    scopus 로고
    • Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
    • Lawlor D. A., Fraser A., Ebrahim S. & Smith G. D. Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women. PLoS Med. 4, e263 (2007).
    • (2007) PLoS Med , vol.4 , pp. e263
    • Lawlor, D.A.1    Fraser, A.2    Ebrahim, S.3    Smith, G.D.4
  • 159
    • 84884370007 scopus 로고    scopus 로고
    • Hemoglobin a1c is associated with increased risk of incident coronary heart disease among apparently healthy, nondiabetic men and women
    • Pai J. K. et al. Hemoglobin a1c is associated with increased risk of incident coronary heart disease among apparently healthy, nondiabetic men and women. J. Am. Heart Assoc. 2, e000077 (2013).
    • (2013) J. Am. Heart Assoc , vol.2 , pp. e000077
    • Pai, J.K.1
  • 160
    • 1842681503 scopus 로고    scopus 로고
    • Hemoglobin A1c level and future cardiovascular events among women
    • Blake G. J. et al. Hemoglobin A1c level and future cardiovascular events among women. Arch. Intern. Med. 164, 757-761 (2004).
    • (2004) Arch. Intern. Med , vol.164 , pp. 757-761
    • Blake, G.J.1
  • 161
    • 77953281382 scopus 로고    scopus 로고
    • Markers of dysglycaemia and r isk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review
    • Sarwar N. et al. Markers of dysglycaemia and r isk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review. PLoS Med. 7, e1000278 (2010).
    • (2010) PLoS Med , vol.7 , pp. e1000278
    • Sarwar, N.1
  • 162
    • 77953821528 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies
    • Sarwar N. et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 375, 2215-2222 (2010).
    • (2010) Lancet , vol.375 , pp. 2215-2222
    • Sarwar, N.1
  • 163
    • 67650094848 scopus 로고    scopus 로고
    • International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes
    • International Expert Committee
    • International Expert Committee. International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 32, 1327-1334 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 1327-1334
  • 164
    • 4644230118 scopus 로고    scopus 로고
    • Glycosylated hemoglobin: Finally ready for prime time as a cardiovascular risk factor
    • Gerstein H. C. Glycosylated hemoglobin: finally ready for prime time as a cardiovascular risk factor. Ann. Intern. Med. 141, 475-476 (2004).
    • (2004) Ann. Intern. Med , vol.141 , pp. 475-476
    • Gerstein, H.C.1
  • 165
    • 0033622152 scopus 로고    scopus 로고
    • Standardization of HbA1c measurements-A consensus statement
    • Marshall S. M. & Barth J. H. Standardization of HbA1c measurements-A consensus statement. Diabet. Med. 17, 5-6 (2000).
    • (2000) Diabet. Med , vol.17 , pp. 5-6
    • Marshall, S.M.1    Barth, J.H.2
  • 166
    • 33644867084 scopus 로고    scopus 로고
    • Combined effects of hemoglobin A1c and C-reactive protein on the progression of subclinical carotid atherosclerosis: The INVADE study
    • Sander D. et al. Combined effects of hemoglobin A1c and C-reactive protein on the progression of subclinical carotid atherosclerosis: the INVADE study. Stroke 37, 351-357 (2006).
    • (2006) Stroke , vol.37 , pp. 351-357
    • Sander, D.1
  • 167
    • 0023940640 scopus 로고
    • Cachectin/TNF and IL-1 induced by glucose-modified proteins: Role in normal tissue remodeling
    • Vlassara H., Brownlee M., Manogue K. R., Dinarello C. A. & Pasagian A. Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science 240, 1546-1548 (1988).
    • (1988) Science , vol.240 , pp. 1546-1548
    • Vlassara, H.1    Brownlee, M.2    Manogue, K.R.3    Dinarello, C.A.4    Pasagian, A.5
  • 168
    • 0042594649 scopus 로고    scopus 로고
    • C-reactive protein and glycemic control in adults with diabetes
    • King D. E., Mainous A. G. III, Buchanan T. A. & Pearson W. S. C-reactive protein and glycemic control in adults with diabetes. Diabetes Care 26, 1535-1539 (2003).
    • (2003) Diabetes Care , vol.26 , pp. 1535-1539
    • King, D.E.1    Mainous, A.G.2    Buchanan, T.A.3    Pearson, W.S.4
  • 169
    • 0037143638 scopus 로고    scopus 로고
    • A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis
    • Verma S. et al. A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation 106, 913-919 (2002).
    • (2002) Circulation , vol.106 , pp. 913-919
    • Verma, S.1
  • 170
    • 0030942586 scopus 로고    scopus 로고
    • Vascular effects of acute hyperglycemia in humans are reversed by L-arginine Evidence for reduced availability of nitric oxide during hyperglycemia
    • Giugliano D. et al. Vascular effects of acute hyperglycemia in humans are reversed by L-arginine. Evidence for reduced availability of nitric oxide during hyperglycemia. Circulation 95, 1783-1790 (1997).
    • (1997) Circulation , vol.95 , pp. 1783-1790
    • Giugliano, D.1
  • 171
    • 77953868829 scopus 로고    scopus 로고
    • More insights on the dysglycaemia-cardiovascular connection
    • Gerstein H. C. More insights on the dysglycaemia-cardiovascular connection. Lancet 375, 2195-2196 (2010).
    • (2010) Lancet , vol.375 , pp. 2195-2196
    • Gerstein, H.C.1
  • 172
    • 0029930899 scopus 로고    scopus 로고
    • Dysglycaemia and risk of cardiovascular disease
    • Gerstei n H. C. & Yusuf S. Dysglycaemia and risk of cardiovascular disease. Lancet 347, 949-950 (1996).
    • (1996) Lancet , vol.347 , pp. 949-950
    • Gerstei, N.H.C.1    Yusuf, S.2
  • 173
    • 84896675182 scopus 로고    scopus 로고
    • Glycated hemoglobin measurement and prediction of cardiovascular disease
    • Emerging Risk Factors Collaboration. Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA 311, 1225-1233 (2014).
    • (2014) JAMA , vol.311 , pp. 1225-1233
  • 174
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler W. C. et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346, 393-403 (2002).
    • (2002) N. Engl. J. Med , vol.346 , pp. 393-403
    • Knowler, W.C.1
  • 175
    • 17144389303 scopus 로고    scopus 로고
    • The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: The Diabetes Prevention Program randomized trial
    • Orchard T. J. et al. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann. Intern. Med. 142, 611-619 (2005).
    • (2005) Ann. Intern. Med , vol.142 , pp. 611-619
    • Orchard, T.J.1
  • 176
    • 15944424370 scopus 로고    scopus 로고
    • Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program
    • Ratner R. et al. Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program. Diabetes Care 28, 888-894 (2005).
    • (2005) Diabetes Care , vol.28 , pp. 888-894
    • Ratner, R.1
  • 177
    • 84901590227 scopus 로고    scopus 로고
    • Cardiovascular mortality all-cause mortality and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the da Qing Diabetes Prevention Study: A 23-year follow-up study
    • Li G. et al. Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: a 23-year follow-up study. Lancet Diabetes Endocrinol. 2, 474-480 (2014).
    • (2014) Lancet Diabetes Endocrinol , vol.2 , Issue.474-480
    • Li, G.1
  • 178
    • 45149131667 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in type 2 diabetes
    • Gerstein H. C. et al Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J.Med. 358 2545-2559 2008).
    • (2008) N. Engl. J.Med , vol.358 , pp. 2545-2559
    • Gerstein, H.C.1
  • 179
    • 77957271422 scopus 로고    scopus 로고
    • In support of an early polypharmacy approach to the treatment of type 2 diabetes
    • Wright E. E. Jr., Stonehouse A. H. & Cuddihy R. M. In support of an early polypharmacy approach to the treatment of type 2 diabetes. Diabetes Obes. Metab. 12, 929-940 (2010).
    • (2010) Diabetes Obes. Metab , vol.12 , pp. 929-940
    • Wright, E.E.1    Stonehouse, A.H.2    Cuddihy, R.M.3
  • 180
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto J. et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 344, 1343-1350 (2001).
    • (2001) N. Engl. J. Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1
  • 181
    • 33751366229 scopus 로고    scopus 로고
    • Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: Follow-up of the Finnish Diabetes Prevention Study
    • Lindstrom J. et al. Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. Lancet 368, 1673-1679 (2006).
    • (2006) Lancet , vol.368 , pp. 1673-1679
    • Lindstrom, J.1
  • 182
    • 0032511583 scopus 로고    scopus 로고
    • [No authors listed Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
    • [No authors listed] Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 352, 837-853 (1998).
    • (1998) Lancet , vol.352 , pp. 837-853
  • 183
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • Patel A. et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N. Engl. J. Med. 358, 2560-2572 (2008).
    • (2008) N. Engl. J. Med , vol.358 , pp. 2560-2572
    • Patel, A.1
  • 184
    • 58149389215 scopus 로고    scopus 로고
    • Glucose control and vascular complications in veterans with type 2 diabetes
    • Duckworth W. et al. Glucose control and vascular complications in veterans with type 2 diabetes. N. Engl. J. Med. 360, 129-139 (2009).
    • (2009) N. Engl. J. Med , vol.360 , pp. 129-139
    • Duckworth, W.1
  • 185
    • 77949521505 scopus 로고    scopus 로고
    • Hapto globin: Basic and clinical aspects
    • Levy A. P. et al. Hapto globin: basic and clinical aspects. Antioxid. Redox Signal. 12, 293-304 (2010).
    • (2010) Antioxid. Redox Signal , vol.12 , pp. 293-304
    • Levy, A.P.1
  • 186
    • 84882790662 scopus 로고    scopus 로고
    • Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant
    • Cahill L. E. et al. Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant. J. Am. Coll. Cardiol. 62, 860-861 (2013).
    • (2013) J. Am. Coll. Cardiol , vol.62 , pp. 860-861
    • Cahill, L.E.1
  • 187
    • 0029854812 scopus 로고    scopus 로고
    • Biological and clinical significance of haptoglobin polymorphism in humans
    • Langlois M. R. & Delanghe J. R. Biological and clinical significance of haptoglobin polymorphism in humans. Clin. Chem. 42, 1589-1600 (1996).
    • (1996) Clin. Chem , vol.42 , pp. 1589-1600
    • Langlois, M.R.1    Delanghe, J.R.2
  • 188
    • 0842281418 scopus 로고    scopus 로고
    • Hap toglobin phenotype and prevalent coronary heart disease in the Framingham offspring cohort
    • Levy A. P. et al. Hap toglobin phenotype and prevalent coronary heart disease in the Framingham offspring cohort. Atherosclerosis 172, 361-365 (2004).
    • (2004) Atherosclerosis , vol.172 , pp. 361-365
    • Levy, A.P.1
  • 189
    • 0034970002 scopus 로고    scopus 로고
    • Haptoglobin polymorphism as a risk factor for coronary heart disease mortality
    • De Bacquer D. et al. Haptoglobin polymorphism as a risk factor for coronary heart disease mortality. Atherosclerosis 157, 161-166 (2001).
    • (2001) Atherosclerosis , vol.157 , pp. 161-166
    • De Bacquer, D.1
  • 190
    • 14844345323 scopus 로고    scopus 로고
    • Haptoglobin genotype-and d iabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo
    • Asleh R., Guetta J., Kalet-Litman S., Miller-Lotan R. & Levy A. P. Haptoglobin genotype-and d iabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo. Circ. Res. 96, 435-441 (2005).
    • (2005) Circ. Res , vol.96 , pp. 435-441
    • Asleh, R.1    Guetta, J.2    Kalet-Litman, S.3    Miller-Lotan, R.4    Levy, A.P.5
  • 191
    • 33845665664 scopus 로고    scopus 로고
    • Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo
    • Asleh R. et al. Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo. Circ. Res. 99, 1419-1425 (2006).
    • (2006) Circ. Res , vol.99 , pp. 1419-1425
    • Asleh, R.1
  • 192
    • 0038042030 scopus 로고    scopus 로고
    • Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease
    • Asleh R. et al. Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease. Circ. Res. 92, 1193-1200(2003).
    • (2003) Circ. Res , vol.92 , pp. 1193-1200
    • Asleh, R.1
  • 193
    • 84873731913 scopus 로고    scopus 로고
    • Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin
    • Cahill L. E. et al. Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin. J. Am. Coll. Cardiol. 61, 728-737 (2013).
    • (2013) J. Am. Coll. Cardiol , vol.61 , pp. 728-737
    • Cahill, L.E.1
  • 194
    • 0037021557 scopus 로고    scopus 로고
    • Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes: The Strong Heart Study
    • Levy A. P. et al. Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes: The Strong Heart Study. J. Am. Coll. Cardiol. 40, 1984-1990 (2002).
    • (2002) J. Am. Coll. Cardiol , vol.40 , pp. 1984-1990
    • Levy, A.P.1
  • 195
    • 79952273819 scopus 로고    scopus 로고
    • Long-term effects of intensive glucose lowering on cardiovascular outcomes
    • Gerstein H. C. et al. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N. Engl. J. Med. 364, 818-828 (2011).
    • (2011) N. Engl. J. Med , vol.364 , pp. 818-828
    • Gerstein, H.C.1
  • 196
    • 34249677215 scopus 로고    scopus 로고
    • Haptoglobin a review of the major allele frequencies worldwide and their association with diseases
    • Carter K. & Worwood M. Haptoglobin: a review of the major allele frequencies worldwide and their association with diseases. Int. J. Lab. Hematol. 29, 92-110 (2007).
    • (2007) Int. J. Lab. Hematol , vol.29 , pp. 92-110
    • Carter, K.1    Worwood, M.2
  • 197
    • 84893314692 scopus 로고    scopus 로고
    • Does the net reclassification improvement help us evaluate models and markers?
    • Vickers A. J. & Pepe M. Does the net reclassification improvement help us evaluate models and markers? Ann. Intern. Med. 160, 136-137 (2014).
    • (2014) Ann. Intern. Med , vol.160 , pp. 136-137
    • Vickers, A.J.1    Pepe, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.