Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of parkinson's disease

FASEB Journal

Volumn 25, Issue 4, 2011, Pages 1333-1344

  Good, Cameron H ^a,b   Hoffman, Alexander F ^a,b   Hoffer, Barry J ^a   Chefer, Vladimir I ^a   Shippenberg, Toni S ^a   Bäckman, Cristina M ^a   Larsson, Nils Göran ^c   Olson, Lars ^d   Gellhaar, Sandra ^d   Galter, Dagmar ^d   Lupica, Carl R ^a,b  

^a U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dopamine; Patch clamp; Striatum; Substantia nigra pars compacta

Indexed keywords

CYCLIC NUCLEOTIDE GATED CHANNEL; DOPAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BRAIN SLICE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; FEMALE; GENETIC TRANSCRIPTION; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; MOUSE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROBIOLOGY; NEUROCHEMISTRY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA PARS COMPACTA;

ANIMALS; CORPUS STRIATUM; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOPAMINE; FEMALE; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; NEURONS; PARKINSON DISEASE; SUBSTANTIA NIGRA; TRANSCRIPTION FACTORS;

MUS; PARKINSONIA;

EID: 79954599799     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-173625     Document Type: Article

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