Alzheimer peptides aggregate into transient nanoglobules that nucleate fibrils

Biochemistry

Volumn 53, Issue 40, 2014, Pages 6302-6308

  Luo, Jinghui ^a   Wärmländer, Sebastian K T S ^b   Gräslund, Astrid ^b   Abrahams, Jan Pieter ^a,c  

^a LEIDEN UNIVERSITY   (Netherlands)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGOMERIZATION; OLIGOMERS; PEPTIDES;

AMYLOID DEPOSITION; BIOPHYSICAL CHARACTERIZATION; FIBRILLAR STRUCTURES; INTERMEDIATE STATE; MESOSCOPIC STATE; SHARP TRANSITION; SLOW AGGREGATIONS; STRAND CONFORMATION;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN[1-40]; NANOGLOBULE; NANOPARTICLE; UNCLASSIFIED DRUG; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); NANOMATERIAL; PEPTIDE FRAGMENT;

ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; PARTICLE SIZE; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE; ALZHEIMER DISEASE; ATOMIC FORCE MICROSCOPY; CELL SURVIVAL; CHEMISTRY; HUMAN; KINETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEINOSIS; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; KINETICS; MICROSCOPY, ATOMIC FORCE; NANOSTRUCTURES; PEPTIDE FRAGMENTS; PROTEIN AGGREGATION, PATHOLOGICAL;

EID: 84908029045     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi5003579     Document Type: Article

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