Caenorhabditis elegans: A model system for anti-cancer drug discovery and therapeutic target identification

Biomolecules and Therapeutics

Volumn 22, Issue 5, 2014, Pages 371-383

  Kobet, Robert A ^a   Pan, Xiaoping ^b   Zhang, Baohong ^b   Pak, Stephen C ^c   Asch, Adam S ^a,d,e   Lee, Myon Hee ^a,d  

^a EAST CAROLINA UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Caenorhabditis elegans; Cancer stem cells; Drug screening; Notch; Ras; Wnt

Indexed keywords

CATENIN; NOTCH RECEPTOR; RAS PROTEIN; WNT PROTEIN;

CAENORHABDITIS ELEGANS; CANCER STEM CELL; CELL FATE; CELL PROLIFERATION; DRUG AFFINITY RESPONSIVE TARGET STABILITY; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; GERMLINE STEM CELL; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL NICHE; WNT SIGNALING PATHWAY;

CAENORHABDITIS ELEGANS;

EID: 84908021063     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2014.084     Document Type: Review

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