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Volumn 11, Issue 4, 2011, Pages 533-540

Notch signaling in lung cancer

Author keywords

cancer progenitor cells; cancer stem cells; hypoxia; lung cancer; Notch signaling; Notch signaling inhibition

Indexed keywords

NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

EID: 79955120560     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.10.158     Document Type: Article
Times cited : (46)

References (57)
  • 2
    • 33750603100 scopus 로고    scopus 로고
    • Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
    • DOI 10.1200/JCO.2005.04.4859
    • Govindan R, Page N, Morgensztern D et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J. Clin. Oncol. 24(28), 4539-4544 (2006). (Pubitemid 46630948)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.28 , pp. 4539-4544
    • Govindan, R.1    Page, N.2    Morgensztern, D.3    Read, W.4    Tierney, R.5    Vlahiotis, A.6    Spitznagel, E.L.7    Piccirillo, J.8
  • 4
    • 77954982964 scopus 로고    scopus 로고
    • Non-small-cell lung cancer
    • 8th Edition De Vita VT Jr Lawrence TS Rosemberg SA Eds. Lippincot Williams & Wilkins PA USA
    • Schrump DS, Giaccone D, Kelsey CR, Marks LB. Non-small-cell lung cancer. In:Cancer, Principles & Practice of Oncology (8th Edition). De Vita VT Jr, Lawrence TS, Rosemberg SA (Eds).Lippincot Williams & Wilkins, PA, USA, 896-946 (2008).
    • (2008) Cancer Principles & Practice of Oncology , pp. 896-946
    • Schrump, D.S.1    Giaccone, D.2    Kelsey, C.R.3    Marks, L.B.4
  • 5
    • 72649087028 scopus 로고    scopus 로고
    • Small cell and other neuroendocrine tumors of the lung
    • 8th Edition De Vita VT Jr Lawrence TS Rosemberg SA Eds. Lippincot Williams & Wilkins PA USA
    • Krug LM, Kris MG, Rosenzweig K, Travis WD. Small cell and other neuroendocrine tumors of the lung. In:Cancer, Principles & Practice of Oncology (8th Edition). De Vita VT Jr, Lawrence TS, Rosemberg SA (Eds).Lippincot Williams & Wilkins, PA, USA, 946-971 (2008).
    • (2008) Cancer Principles & Practice of Oncology , pp. 946-971
    • Krug, L.M.1    Kris, M.G.2    Rosenzweig, K.3    Travis, W.D.4
  • 6
    • 0035182533 scopus 로고    scopus 로고
    • Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations
    • DOI 10.1146/annurev.cellbio.17.1.387
    • Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu. Rev. Cell Dev. Biol. 17, 387-403 (2001). (Pubitemid 33096181)
    • (2001) Annual Review of Cell and Developmental Biology , vol.17 , pp. 387-403
    • Weissman, I.L.1    Anderson, D.J.2    Gage, F.3
  • 9
    • 1542319868 scopus 로고    scopus 로고
    • Basal Cells Are a Multipotent Progenitor Capable of Renewing the Bronchial Epithelium
    • Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am. J. Pathol. 164(2), 577-588 (2004). (Pubitemid 38364673)
    • (2004) American Journal of Pathology , vol.164 , Issue.2 , pp. 577-588
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3    Fuchs, E.4    Stripp, B.R.5
  • 10
    • 0036314791 scopus 로고    scopus 로고
    • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
    • Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am. J. Pathol. 161(1), 173-182 (2002). (Pubitemid 34760783)
    • (2002) American Journal of Pathology , vol.161 , Issue.1 , pp. 173-182
    • Giangreco, A.1    Reynolds, S.D.2    Stripp, B.R.3
  • 12
    • 58349091690 scopus 로고    scopus 로고
    • G-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    • Meng RD, Shelton CC, Li YM et al. g-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Res. 69(2), 573-582 (2009).
    • (2009) CancerRes. , vol.69 , Issue.2 , pp. 573-582
    • Meng, R.D.1    Shelton, C.C.2    Li, Y.M.3
  • 13
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 6(5), 963-968 (1953).
    • (1953) Cancer , vol.6 , Issue.5 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 15
    • 0036163796 scopus 로고    scopus 로고
    • ABC transporters as phenotypic markers and functional regulators of stem cells
    • Bunting KD. ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cell 20(1), 11-20 (2002). (Pubitemid 34118906)
    • (2002) Stem Cells , vol.20 , Issue.1 , pp. 11-20
    • Bunting, K.D.1
  • 16
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • DOI 10.1158/0008-5472.CAN-06-3557
    • Ho MM, Ng AV, Lam S, Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 67(10), 4827-4833 (2007). (Pubitemid 46910191)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 17
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • DOI 10.1016/j.cell.2007.04.019, PII S0092867407005259
    • Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 129(3), 465-472 (2007). (Pubitemid 46660978)
    • (2007) Cell , vol.129 , Issue.3 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 18
    • 39749172398 scopus 로고    scopus 로고
    • Tumor hypoxia in cancer therapy
    • Brown JM. Tumor hypoxia in cancer therapy. Methods Enzymol. 435, 297-321 (2007).
    • (2007) Methods Enzymol. , vol.435 , pp. 297-321
    • Brown, J.M.1
  • 19
    • 60649100252 scopus 로고    scopus 로고
    • Cancer stem cells and tumor response to therapy: Current problems and future prospects
    • Milas L, Hittelman WN. Cancer stem cells and tumor response to therapy: current problems and future prospects. Semin. Radiat. Oncol. 19(2), 96-105 (2009).
    • (2009) Semin. Radiat. Oncol. , vol.19 , Issue.2 , pp. 96-105
    • Milas, L.1    Hittelman, W.N.2
  • 21
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15(6), 501-513 (2009).
    • (2009) CancerCell , vol.15 , Issue.6 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3
  • 22
    • 77951880179 scopus 로고    scopus 로고
    • Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
    • Eliasz S, Liang S, Chen Y et al. Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene 29(17), 2488-2498 (2010).
    • (2010) Oncogene , vol.29 , Issue.17 , pp. 2488-2498
    • Eliasz, S.1    Liang, S.2    Chen, Y.3
  • 25
    • 76549084826 scopus 로고    scopus 로고
    • Regulation of breast cancer stem cell activity by signaling through the notch4 receptor
    • Harrison H, Farnie G, Howell SJ et al. Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res. 70(2), 709-718 (2010).
    • (2010) CancerRes. , vol.70 , Issue.2 , pp. 709-718
    • Harrison, H.1    Farnie, G.2    Howell, S.J.3
  • 26
    • 78649960144 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling
    • Sullivan JP, Spinola M, Dodge M et al. Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Res. 70(23), 9937-9948 (2010).
    • (2010) CancerRes. , vol.70 , Issue.23 , pp. 9937-9948
    • Sullivan, J.P.1    Spinola, M.2    Dodge, M.3
  • 27
    • 33644752839 scopus 로고    scopus 로고
    • Notch signaling
    • DOI 10.1158/1078-0432.CCR-05-2570
    • Miele L. Notch signaling. Clin. Cancer Res. 12(4), 1074-1079 (2006). (Pubitemid 43342494)
    • (2006) Clinical Cancer Research , vol.12 , Issue.4 , pp. 1074-1079
    • Miele, L.1
  • 29
    • 34548599785 scopus 로고    scopus 로고
    • Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
    • DOI 10.1158/0008-5472.CAN-07-1229
    • Chen Y, De Marco MA, Graziani I et al. Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res. 67(17), 7954-7959 (2007). (Pubitemid 47395124)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 7954-7959
    • Chen, Y.1    De Marco, M.A.2    Graziani, I.3    Gazdar, A.F.4    Strack, P.R.5    Miele, L.6    Bocchetta, M.7
  • 30
    • 57149084692 scopus 로고    scopus 로고
    • Opposite effects of notch-1 and notch-2 on mesothelioma cell survival under hypoxia are exerted through the akt pathway
    • Graziani I, Eliasz S, De Marco MA et al. Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. Cancer Res. 68(23), 9678-9685 (2008).
    • (2008) CancerRes. , vol.68 , Issue.23 , pp. 9678-9685
    • Graziani, I.1    Eliasz, S.2    De Marco, M.A.3
  • 33
    • 0032868937 scopus 로고    scopus 로고
    • Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality
    • Hamada Y, Kadokawa Y, Okabe M, Ikawa M, Coleman JR, Tsujimoto Y. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126(15), 3415-3424 (1999). (Pubitemid 29396781)
    • (1999) Development , vol.126 , Issue.15 , pp. 3415-3424
    • Hamada, Y.1    Kadokawa, Y.2    Okabe, M.3    Ikawa, M.4    Coleman, J.R.5    Tsujimoto, Y.6
  • 35
    • 0033792527 scopus 로고    scopus 로고
    • Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium
    • Ito T, Udaka N, Yazawa T et al. Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 127(18), 3913-3921 (2000).
    • (2000) Development , vol.127 , Issue.18 , pp. 3913-3921
    • Ito, T.1    Udaka, N.2    Yazawa, T.3
  • 36
    • 78650082224 scopus 로고    scopus 로고
    • Prognostic impact of notch ligands and receptors in nonsmall cell lung cancer: Coexpression of notch-1 and vascular endothelial growth factor-A predicts poor survival
    • Donnem T, Andersen S, Al-Shibli K et al. Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer: coexpression of Notch-1 and vascular endothelial growth factor-A predicts poor survival. Cancer 116(24), 5676-5685 (2010).
    • (2010) Cancer , vol.116 , Issue.24 , pp. 5676-5685
    • Donnem, T.1    Andersen, S.2    Al-Shibli, K.3
  • 39
    • 29144499299 scopus 로고    scopus 로고
    • Hairy Enhancer of Split-1 (HES-1), a Notch1 effector, inhibits the growth of carcinoid tumor cells
    • DOI 10.1016/j.surg.2005.05.027, PII S0039606005005180
    • Kunnimalaiyaan M, Yan S, Wong F, Zhang YW, Chen H. Hairy enhancer of split-1 (HES-1), a Notch1 effector, inhibits the growth of carcinoid tumor cells. Surgery 138(6), 1137-1142 (2005). (Pubitemid 41797355)
    • (2005) Surgery , vol.138 , Issue.6 , pp. 1137-1142
    • Kunnimalaiyaan, M.1    Yan, S.2    Wong, F.3    Zhang, Y.-W.4    Chen, H.5    Skogseid, B.6    Dackiw, A.P.B.7    Kebebew, E.8
  • 40
    • 34249936877 scopus 로고    scopus 로고
    • Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549
    • Zheng Q, Qin H, Zhang H et al. Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549. Oncol. Rep. 17(4), 847-852 (2007).
    • (2007) Oncol. Rep. , vol.17 , Issue.4 , pp. 847-852
    • Zheng, Q.1    Qin, H.2    Zhang, H.3
  • 42
    • 76049110053 scopus 로고    scopus 로고
    • Alterations of the notch pathway in lung cancer
    • USA
    • Westhoff B, Colaluca IN, D'Ario G et al. Alterations of the Notch pathway in lung cancer. Proc. Natl Acad. Sci. USA 106(52), 22293-22298 (2009).
    • (2009) Proc. Natl Acad. Sci. , vol.106 , Issue.52 , pp. 22293-22298
    • Westhoff, B.1    Colaluca, I.N.2    D'Ario, G.3
  • 43
    • 78751503434 scopus 로고    scopus 로고
    • Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells
    • Chen Y, Li D, Liu H et al. Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells. Cancer Biol. Ther. 11(1), 14-21 (2011).
    • (2011) CancerBiol. Ther. , vol.11 , Issue.1 , pp. 14-21
    • Chen, Y.1    Li, D.2    Liu, H.3
  • 44
    • 77954350599 scopus 로고    scopus 로고
    • ADAM17 regulates epidermal growth factor receptor expression through the activation of notch1 in non-small cell lung cancer
    • Baumgart A, Seidl S, Vlachou P et al. ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer. Cancer Res. 70(13), 5368-5378 (2010).
    • (2010) CancerRes. , vol.70 , Issue.13 , pp. 5368-5378
    • Baumgart, A.1    Seidl, S.2    Vlachou, P.3
  • 46
    • 0025720075 scopus 로고
    • Intrathoracic carcinoma in an 11-year-old girl showing a translocation t 15;19
    • Kees UR, Mulcahy MT, Willoughby ML. Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19).Am. J. Pediatr. Hematol. Oncol. 13(4), 459-464 (1991).
    • (1991) Am. J. Pediatr. Hematol. Oncol. , vol.13 , Issue.4 , pp. 459-464
    • Kees, U.R.1    Mulcahy, M.T.2    Willoughby, M.L.3
  • 47
    • 0027275415 scopus 로고
    • Disseminated mediastinal carcinoma with chromosomal translocation (15;19): A distinctive clinicopathologic syndrome
    • Lee AC, Kwong YI, Fu KH, Chan GC, Ma L, Lau YL. Disseminated mediastinal carcinoma with chromosomal translocation (15;19).A distinctive clinicopathologic syndrome. Cancer 72(7), 2273-2276 (1993). (Pubitemid 23280160)
    • (1993) Cancer , vol.72 , Issue.7 , pp. 2273-2276
    • Lee, A.C.W.1    Kwong, Y.-L.2    Fu, K.H.3    Chan, G.C.F.4    Ma, L.5    Lau, Y.-L.6
  • 48
    • 0025742958 scopus 로고
    • Novel t 15;19 q15;p13 chromosome abnormality in a thymic carcinoma
    • Kubonishi I, Takehara N, Iwata J et al. Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma. Cancer Res. 51(12), 3327-3328 (1991).
    • (1991) CancerRes. , vol.51 , Issue.12 , pp. 3327-3328
    • Kubonishi, I.1    Takehara, N.2    Iwata, J.3
  • 50
    • 75749138443 scopus 로고    scopus 로고
    • Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim
    • Konishi J, Yi F, Chen X, Vo H, Carbone DP, Dang TP. Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim. Oncogene 29(4), 589-596 (2010).
    • (2010) Oncogene , vol.29 , Issue.4 , pp. 589-596
    • Konishi, J.1    Yi, F.2    Chen, X.3    Vo, H.4    Carbone, D.P.5    Dang, T.P.6
  • 51
    • 35648949422 scopus 로고    scopus 로고
    • BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
    • Costa DB, Halmos B, Kumar A et al. BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations. PLoS Med. 4(10), 1669-1679 (2007).
    • (2007) PLoS Med. , vol.4 , Issue.10 , pp. 1669-1679
    • Costa, D.B.1    Halmos, B.2    Kumar, A.3
  • 52
    • 34548572895 scopus 로고    scopus 로고
    • γ-Secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers
    • DOI 10.1158/0008-5472.CAN-07-1022
    • Konishi J, Kawaguchi KS, Vo H et al. g-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers. Cancer Res. 67(17), 8051-8057 (2007). (Pubitemid 47395139)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 8051-8057
    • Konishi, J.1    Kawaguchi, K.S.2    Vo, H.3    Haruki, N.4    Gonzalez, A.5    Carbone, D.P.6    Dang, T.P.7
  • 53
    • 76549124723 scopus 로고    scopus 로고
    • Targeting specific regions of the notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer
    • Lin L, Mernaugh R, Yi F, Blum D, Carbone DP, Dang TP. Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer. Cancer Res. 70(2), 632-638 (2010).
    • (2010) CancerRes. , vol.70 , Issue.2 , pp. 632-638
    • Lin, L.1    Mernaugh, R.2    Yi, F.3    Blum, D.4    Carbone, D.P.5    Dang, T.P.6
  • 54
    • 0037417132 scopus 로고    scopus 로고
    • Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice
    • DOI 10.1038/sj.onc.1206230
    • Dang TP, Eichenberger S, Gonzalez A, Olson S, Carbone DP. Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice. Oncogene 22(13), 1988-1997 (2003). (Pubitemid 36523636)
    • (2003) Oncogene , vol.22 , Issue.13 , pp. 1988-1997
    • Dang, T.P.1    Eichenberger, S.2    Gonzalez, A.3    Olson, S.4    Carbone, D.P.5
  • 55
    • 70449671729 scopus 로고    scopus 로고
    • Direct inhibition of the notch transcription factor complex
    • Moellering RE, Cornejo M, Davis TN et al. Direct inhibition of the NOTCH transcription factor complex. Nature 462(7270), 182-188 (2009).
    • (2009) Nature , vol.462 , Issue.7270 , pp. 182-188
    • Moellering, R.E.1    Cornejo, M.2    Davis, T.N.3
  • 56
    • 77951139188 scopus 로고    scopus 로고
    • Therapeutic antibody targeting of individual notch receptors
    • Wu Y, Cain-Hom C, Choy L et al. Therapeutic antibody targeting of individual Notch receptors. Nature 464(7291), 1052-1057 (2010).
    • (2010) Nature , vol.464 , Issue.7291 , pp. 1052-1057
    • Wu, Y.1    Cain-Hom, C.2    Choy, L.3
  • 57
    • 48749089743 scopus 로고    scopus 로고
    • Loss of intestinal crypt progenitor cells owing to inactivation of both notch1 and notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
    • Riccio O, van Gijn ME, Bezdek AC et al. Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep. 9(4), 377-383 (2008).
    • (2008) EMBO Rep. , vol.9 , Issue.4 , pp. 377-383
    • Riccio, O.1    Van Gijn, M.E.2    Bezdek, A.C.3


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