A high-content assay for identifying small molecules that reprogram C. elegans germ cell fate

Methods

Volumn 68, Issue 3, 2014, Pages 529-535

  Benson, Joshua A ^a   Cummings, Erin E ^a   O'Reilly, Linda P ^a   Lee, Myon Hee ^b,c   Pak, Stephen C ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

C. elegans; Cell fate; Drug screening; High content screening; Reprogramming

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MOLECULAR LIBRARY;

ARTICLE; CAENORHABDITIS ELEGANS; CELL FATE; CHROMOSOME; CONTROLLED STUDY; GENOTYPE; GERM CELL; HETEROZYGOTE; HOMOZYGOTE; NONHUMAN; OOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROGENY; SPERM; WORKFLOW; ADMINISTRATION AND DOSAGE; ANIMAL; CELL LINEAGE; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HIGH THROUGHPUT SCREENING; MALE; MOLECULAR LIBRARY; NUCLEAR REPROGRAMMING; SIGNAL TRANSDUCTION;

ANIMALIA; CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CELL LINEAGE; CELLULAR REPROGRAMMING; GERM CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; MALE; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES;

EID: 84904624359     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2014.05.011     Document Type: Article

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