Selective interception of gelsolin amyloidogenic stretch results in conformationally distinct aggregates with reduced toxicity

ACS Chemical Neuroscience

Volumn 5, Issue 10, 2014, Pages 982-992

  Arya, Prabha ^a   Srivastava, Ankit ^a   Vasaikar, Suhas V ^a   Mukherjee, Goutam ^a   Mishra, Prashant ^a   Kundu, Bishwajit ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

Amyloid; Curcumin; Cytotoxicity; Emetine; Gelsolin; Oligomer

Indexed keywords

AMYLOID PROTEIN; CURCUMIN; EMETINE; GELSOLIN; NATURAL PRODUCT; OLIGOMER; THIOFLAVINE; AMYLOID; PEPTIDE; THIAZOLE DERIVATIVE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL STRUCTURE; CYTOTOXICITY; FIBER; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; LIGHT SCATTERING; MOLECULAR DOCKING; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; SIMULATION; SPECIES; CHEMICAL PHENOMENA; CHEMISTRY; FLUORESCENCE; GENETICS; INFRARED SPECTROSCOPY; KINETICS; LIGHT; PARTICLE SIZE; RADIATION SCATTERING;

AMYLOID; CURCUMIN; EMETINE; FLUORESCENCE; GELSOLIN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; LIGHT; MICROSCOPY, ATOMIC FORCE; MOLECULAR DOCKING SIMULATION; PARTICLE SIZE; PEPTIDES; SCATTERING, RADIATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIAZOLES;

EID: 84907998419     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500002v     Document Type: Article

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