Short amino acid stretches can mediate amyloid formation in globular proteins: The Src homology 3 (SH3) case

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 19, 2004, Pages 7258-7263

  Ventura, Salvador ^a   Zurdo, Jesús ^a,b   Narayanan, Saravanakumar ^c   Parreño, Matilde ^d   Mangues, Ramón ^d   Reif, Bernd ^c   Chiti, Fabrizio ^e   Giannoni, Elisa ^e   Dobson, Christopher M ^b   Aviles, Francesc X ^a   Serrano, Luis ^f  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e UNIVERSITY OF FLORENCE   (Italy)

^f EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Protein aggregation; Protein evolution; Protein misfolding

Indexed keywords

AMINO ACID; AMYLOID; AMYLOID PROTEIN; FODRIN; GLOBULAR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P58ALPHA; PROTEIN SH3; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; CATTLE; CYTOTOXICITY; HUMAN; IN VITRO STUDY; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN STRUCTURE; SRC HOMOLOGY DOMAIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; AMYLOID; ANIMALS; CATTLE; CIRCULAR DICHROISM; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTRIN; SRC HOMOLOGY DOMAINS;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 2442553006     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308249101     Document Type: Article

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