Inhibiting transthyretin conformational changes that lead to amyloid fibril formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 22, 1998, Pages 12956-12960

  Peterson, Scott A ^a   Klabunde, Thomas ^b   Lashuel, Hilal A ^a   Purkey, Hans ^a   Sacchettini, James C ^b   Kelly, Jeffrey W ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; FLUFENAMIC ACID; PREALBUMIN; PROTEIN INHIBITOR;

ALZHEIMER DISEASE; AMYLOID NEUROPATHY; AMYLOIDOSIS; ARTICLE; CALORIMETRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; ULTRACENTRIFUGATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYLOID; AMYLOIDOSIS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; FLUFENAMIC ACID; HUMANS; LYSOSOMES; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PREALBUMIN; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS;

EID: 0032573082     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.22.12956     Document Type: Article

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