Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype

ACS Chemical Neuroscience

Volumn 5, Issue 10, 2014, Pages 908-919

  Angoa Pérez, Mariana ^a,b   Kane, Michael J ^a,b   Briggs, Denise I ^a,b   Herrera Mundo, Nieves ^a,b   Sykes, Catherine E ^a,b   Francescutti, Dina M ^a,b   Kuhn, Donald M ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

depression like behavior; Serotonin; SERT; SSRIs; TPH2; TPH2 knock out

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; FLUOXETINE; PAROXETINE; QUININE; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SUCROSE; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2; SLC6A4 PROTEIN, MOUSE; SUGAR INTAKE; TPH2 PROTEIN, MOUSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN LEVEL; CENTRAL NERVOUS SYSTEM; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; FOOD INTAKE; FORCED SWIM TEST; GENOTYPE; IMMOBILITY; LEARNED HELPLESSNESS; MOUSE; NONHUMAN; SEROTONINERGIC SYSTEM; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; WILD TYPE; ADMINISTRATION AND DOSAGE; ANHEDONIA; ANIMAL; BRAIN; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; DRUG THERAPY; FEMALE; GENETICS; KNOCKOUT MOUSE; MALE; MENTAL STRESS; METABOLISM; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; SUGAR INTAKE; SYNAPTOSOME; TASTE;

MUS;

ANHEDONIA; ANIMALS; BRAIN; DEPRESSION; DIETARY SUCROSE; FEMALE; HELPLESSNESS, LEARNED; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TESTS; PHENOTYPE; QUININE; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; STRESS, PSYCHOLOGICAL; SYNAPTOSOMES; TASTE PERCEPTION; TRYPTOPHAN HYDROXYLASE;

EID: 84907997029     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500096g     Document Type: Article

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