Effect of fluoxetine on a neuronal, voltage-dependent potassium channel (Kv1.1)

British Journal of Pharmacology

Volumn 122, Issue 7, 1997, Pages 1417-1424

  Tytgat, J ^a   Maertens, Ch ^a   Daenens, P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Fluoxetine; Oocytes; Potassium channels; Voltage clamp

Indexed keywords

FLUOXETINE; POTASSIUM CHANNEL; POTASSIUM ION; SEROTONIN UPTAKE INHIBITOR;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; EXPERIMENTAL MODEL; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; REPOLARIZATION; VOLTAGE CLAMP; XENOPUS LAEVIS;

EID: 0030819235     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701545     Document Type: Article

References (32)

1. ASBERG, M., ERIKSSON, B., MARTENSSON, B., TRASKMANBENDZ, L. & WAGNER, J. (1986). Therapeutic effects of serotonin uptake inhibitors in depression. J. Clin. Psychiatry, 47, 23-35.
2. BAUMANN, A., GRUPE, A., ACKERMANN, A. & PONGS, O. (1988). Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous system. EMBO J., 7, 2457-2463.
3. BEZANILLA, F. & ARMSTRONG, C.M. (1977). Inactivation of the sodium channel. I. Sodium current experiments. J. Gen. Physiol., 70, 549-566.
4. + current by almokalant in rabbit ventricular myocytes. Circ. Res., 73, 857-868.
5. CHOI, K., MOSSMAN, C., AUBE, J. & YELLEN, G. (1993). The internal quaternary ammonium receptor site of Shaker potassium channels. Neuron, 10, 533-541.
6. COLQUHOUN, D. & HAWKES, A.G. (1995). The principles of the stochastic interpretation of ion-channel mechanisms. In Single-Channel Recording. ed. Sakmann, B. & Neher, E. pp. 397-482. London: Plenum Press.
7. CUSACK, B., NELSON, A. & RICHELSON, E. (1994). Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology, 114, 559-565.
8. DEAL, K.K., ENGLAND, S.K. & TAMKUN, M.M. (1996). Molecular physiology of cardiac potassium channels. Physiol. Rev., 76, 49-67.
9. FOLLMER, C., CULLINAN, C. & COLATSKY, T. (1992). Differential block of cardiac delayed rectifier current by class Ic antiarrhythmic drugs: evidence for open channel block and unblock. Cardiovasc. Res., 26, 1121-1130.
10. FRANKENHAEUSER, B. & HODGKIN, A.L. (1957). The action of calcium on the electrical properties of squid axons. J. Physiol., 137, 218-244.
11. 3+ block of the currents expressed in Xenopus oocytes. Pflügers Arch., 426, 139-145.
12. HODGKIN, A.L. & HUXLEY, A.F. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol., 117, 500-544.
13. KOREN, G., LIMAN, E.R., LOGOTHETIS, D.E., NADAL-GINARD, B. & HESS, P. (1990). Gating mechanisms of a cloned potassium channel expressed in frog oocytes and mammalian cells. Neuron, 4, 39-51.
14. + channel determined by construction of multimeric cDNAs. Neuron, 9, 861-871.
15. MACKINNON, R. (1991). Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature, 350, 232-235.
16. PRESKORN, S.H., SILKEY, B. BEBER, J. & DOREY, C. (1991). Antidepressant response and plasma concentrations of fluoxetine. Ann. Clin. Psych., 3, 147-151.
17. RAE, J.L., RICH, A., ZAMUDIO, A.C. & CANDIA, O.A. (1995). Effect of Prozac on whole cell ionic currents in lens and corneal epithelia. Am. J. Physiol., 269, C250-C256.
18. RICHELSON, E. & NELSON, A. (1984). Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. J. Pharmacol. Exp. Ther., 230, 94-102.
19. RICHELSON, E. & PFENNING, M. (1984). Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: most antidepressants selectively block norepinephrine uptake. Eur. J. Pharmacol., 104, 277-286.
20. K and screens membrane surface in cardiac cells. Am. J. Physiol., 259, H1881-H1889.
21. SNYDERS, D.J., KNOTH, K., ROBERDS, S. & TAMKUN, M. (1992). Time-, state- and voltage-dependent block by quinidine of a cloned human cardiac channel. Mol. Pharmacol., 41, 332-339.
22. SPORER, K.A. (1995). The serotonin syndrome. Implicated drugs, pathophysiology and management. Drug Safety, 13, 94-104.
23. 2+-channel inhibition. Life Sci., 50, 2125-2138.
24. STERNBACH, H. (1991). The serotonin syndrome. Am. J. Psychiatry, 148, 705-713.
25. TYTGAT, J. & DAENENS, P. (1997). Effect of lanthanum on voltage-dependent gating of a cloned mammalian neuronal potassium channel. Brain Res., 749, 232-237.
26. VALENZUELA, C., DELPON, E., TAMKUN, M.M., TAMARGO, J. & SNYDERS, D.J. (1995). Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers. Biophys. J., 69, 418-427.
27. VEH, R.W., LICHTINGHAGEN, R., SEWING, S., WUNDER, F., GRUMBACH, I.M. & PONGS, O. (1995). Immunohistochemical localization of five members of the Kv1 channel subunits: contrasting subcellular locations and neuron-specific co-localizations in rat brain. Eur. J. Neurosci., 7, 2189-2205.
28. WANG, H., KUNDEL, D.D., SCHWARTZKROIN, P.A. & TEMPEL, B.L. (1994). Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain. J. Neurosci., 14, 4588-4599.
29. WONG, D.T., BYMASTER, F.P. & ENGLEMAN, E.A. (1995). Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. Life Sci., 57, 411-441.
30. WONG, D.T., BYMASTER, F.P., REID, L.R. & THRELKELD, P.G. (1983). Fluoxetine and two other serotonin uptake inhibitors without affinity for neuronal receptors. Biochem. Pharmacol., 32, 1287-1293.
31. WOODHULL, A. (1973). Ionic blockade of sodium channels in nerve. J. Gen. Physiol., 61, 687-708.
32. ZAMUDIO, A.C. & CANDIA, O.A. (1993). Antidepressants and an H1 blocker reduce CI transport in frog corneal epithelium by decreasing K permeability. Invest. Ophthalmol. Visual. Sci., 34, 1400.