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Volumn 2, Issue , 2012, Pages

Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin

Author keywords

aggression; anxiety; depression; serotonin; tryptophan hydroxylase

Indexed keywords

SEROTONIN; TRYPTOPHAN HYDROXYLASE 2; TPH2 PROTEIN, MOUSE; TRYPTOPHAN HYDROXYLASE;

EID: 84861653106     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2012.44     Document Type: Article
Times cited : (200)

References (84)
  • 1
    • 0141922899 scopus 로고    scopus 로고
    • A unique central tryptophan hydroxylase isoform
    • DOI 10.1016/S0006-2952(03)00556-2
    • Walther DJ, Bader M. A unique central tryptophan hydroxylase isoform. Biochem Pharmacol 2003; 66: 1673-1680. (Pubitemid 37249312)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.9 , pp. 1673-1680
    • Walther, D.J.1    Bader, M.2
  • 3
    • 49749117799 scopus 로고    scopus 로고
    • Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice
    • Gutknecht L,Waider J, Kraft S, Kriegebaum C, Holtmann B, Reif A et al. Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice. J Neural Transm 2008; 115: 1127-1132.
    • (2008) J. Neural. Transm. , vol.115 , pp. 1127-1132
    • Gutknecht, L.1    Waider, J.2    Kraft, S.3    Kriegebaum, C.4    Holtmann, B.5    Reif, A.6
  • 4
    • 1042277736 scopus 로고    scopus 로고
    • Robust and tissue-specific expression of TPH2 versus TPH1 in rat raphe and pineal gland
    • DOI 10.1016/j.biopsych.2003.09.002
    • Patel PD, Pontrello C, Burke S. Robust and tissue-specific expression of TPH2 versus TPH1 in rat raphe and pineal gland. Biol Psychiatry 2004; 55: 428-433. (Pubitemid 38199994)
    • (2004) Biological Psychiatry , vol.55 , Issue.4 , pp. 428-433
    • Patel, P.D.1    Pontrello, C.2    Burke, S.3
  • 5
    • 59649097035 scopus 로고    scopus 로고
    • Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice
    • Neal KB, Parry LJ, Bornstein JC. Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice. J Physiol 2009; 587: 567-586.
    • (2009) J. Physiol. , vol.587 , pp. 567-586
    • Neal, K.B.1    Parry, L.J.2    Bornstein, J.C.3
  • 6
    • 2442542996 scopus 로고    scopus 로고
    • Regional mRNA expression of a second tryptophan hydroxylase isoform in postmortem tissue samples of two human brains
    • DOI 10.1016/j.euroneuro.2003.10.002, PII S0924977X03002086
    • Zill P, Buttner A, Eisenmenger W, Bondy B, Ackenheil M. Regional mRNA expression of a second tryptophan hydroxylase isoform in postmortem tissue samples of two human brains. Eur Neuropsychopharmacol 2004; 14: 282-284. (Pubitemid 38649084)
    • (2004) European Neuropsychopharmacology , vol.14 , Issue.4 , pp. 282-284
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3    Bondy, B.4    Ackenheil, M.5
  • 7
    • 33646542677 scopus 로고    scopus 로고
    • Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies
    • DOI 10.1016/j.brainres.2006.02.047, PII S0006899306004550
    • Sakowski SA, Geddes TJ, Thomas DM, Levi E, Hatfield JS, Kuhn DM. Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies. Brain Res 2006; 1085: 11-18. (Pubitemid 43728204)
    • (2006) Brain Research , vol.1085 , Issue.1 , pp. 11-18
    • Sakowski, S.A.1    Geddes, T.J.2    Thomas, D.M.3    Levi, E.4    Hatfield, J.S.5    Kuhn, D.M.6
  • 9
    • 79953733493 scopus 로고    scopus 로고
    • Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice
    • Liu Y, Jiang Y, Si Y, Kim JY, Chen ZF, Rao Y. Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice. Nature 2011; 472: 95-99.
    • (2011) Nature , vol.472 , pp. 95-99
    • Liu, Y.1    Jiang, Y.2    Si, Y.3    Kim, J.Y.4    Chen, Z.F.5    Rao, Y.6
  • 10
    • 54849404294 scopus 로고    scopus 로고
    • Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    • Savelieva KV, Zhao S, Pogorelov VM, Rajan I, Yang Q, Cullinan E et al. Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants. PLoS One 2008; 3: e3301.
    • (2008) PLoS One , vol.3
    • Savelieva, K.V.1    Zhao, S.2    Pogorelov, V.M.3    Rajan, I.4    Yang, Q.5    Cullinan, E.6
  • 11
    • 78651289938 scopus 로고    scopus 로고
    • The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum
    • Thomas DM, Angoa Perez M, Francescutti-Verbeem DM, Shah MM, Kuhn DM. The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum. J Neurochem 2010; 115: 595-605.
    • (2010) J. Neurochem. , vol.115 , pp. 595-605
    • Thomas, D.M.1    Angoa Perez, M.2    Francescutti-Verbeem, D.M.3    Shah, M.M.4    Kuhn, D.M.5
  • 12
    • 69449083603 scopus 로고    scopus 로고
    • A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
    • Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C et al. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009; 138: 976-989.
    • (2009) Cell , vol.138 , pp. 976-989
    • Yadav, V.K.1    Oury, F.2    Suda, N.3    Liu, Z.W.4    Gao, X.B.5    Confavreux, C.6
  • 13
    • 33745726353 scopus 로고    scopus 로고
    • The genetics of depression: A review
    • Levinson DF. The genetics of depression: a review. Biol Psychiatry 2006; 60: 84-92.
    • (2006) Biol Psychiatry , vol.60 , pp. 84-92
    • Levinson, D.F.1
  • 14
    • 78649906500 scopus 로고    scopus 로고
    • Overview of the genetics of major depressive disorder
    • Lohoff FW. Overview of the genetics of major depressive disorder. Curr Psychiatry Rep 2010; 12: 539-546.
    • (2010) Curr. Psychiatry Rep. , vol.12 , pp. 539-546
    • Lohoff, F.W.1
  • 15
    • 75549091083 scopus 로고    scopus 로고
    • Tryptophan hydroxylase as novel target for the treatment of depressive disorders
    • Matthes S, Mosienko V, Bashammakh S, Alenina N, Bader M. Tryptophan hydroxylase as novel target for the treatment of depressive disorders. Pharmacology 2010; 85: 95-109.
    • (2010) Pharmacology , vol.85 , pp. 95-109
    • Matthes, S.1    Mosienko, V.2    Bashammakh, S.3    Alenina, N.4    Bader, M.5
  • 17
    • 5044238471 scopus 로고    scopus 로고
    • SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression
    • DOI 10.1038/sj.mp.4001525
    • Zill P, Baghai TC, Zwanzger P, Schule C, Eser D, Rupprecht R et al. SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression. Mol Psychiatry 2004; 9: 1030-1036. (Pubitemid 39524291)
    • (2004) Molecular Psychiatry , vol.9 , Issue.11 , pp. 1030-1036
    • Zill, P.1    Baghai, T.C.2    Zwanzger, P.3    Schule, C.4    Eser, D.5    Rupprecht, R.6    Moller, H.-J.7    Bondy, B.8    Ackenheil, M.9
  • 18
    • 43149099436 scopus 로고    scopus 로고
    • Molecular genetics of anxiety in mice and men
    • DOI 10.1080/07853890701747096, PII 786930413
    • Hovatta I, Barlow C. Molecular genetics of anxiety in mice and men. Ann Med 2008; 40: 92-109. (Pubitemid 351640644)
    • (2008) Annals of Medicine , vol.40 , Issue.2 , pp. 92-109
    • Hovatta, I.1    Barlow, C.2
  • 19
    • 67651095787 scopus 로고    scopus 로고
    • Genetics of human aggressive behaviour
    • Craig IW, Halton KE. Genetics of human aggressive behaviour. Hum Genet 2009; 126: 101-113.
    • (2009) Hum. Genet. , vol.126 , pp. 101-113
    • Craig, I.W.1    Halton, K.E.2
  • 20
    • 79551574747 scopus 로고    scopus 로고
    • Association of polymorphisms of the serotonergic pathways with clinical traits of impulsive-aggression and suicidality in adolescents: A multi-center study
    • Zalsman G, Patya M, Frisch A, Ofek H, Schapir L, Blum I et al. Association of polymorphisms of the serotonergic pathways with clinical traits of impulsive-aggression and suicidality in adolescents: a multi-center study. World J Biol Psychiatry 2011; 12: 33-41.
    • (2011) World J. Biol. Psychiatry , vol.12 , pp. 33-41
    • Zalsman, G.1    Patya, M.2    Frisch, A.3    Ofek, H.4    Schapir, L.5    Blum, I.6
  • 21
    • 0022528874 scopus 로고
    • Consistent evidence for a biological subtype of depression characterized by low CSF monoamine levels
    • Gibbons RD, Davis JM. Consistent evidence for a biological subtype of depression characterized by low CSF monoamine levels. Acta Psychiatr Scand 1986; 74: 8-12. (Pubitemid 16061280)
    • (1986) Acta Psychiatrica Scandinavica , vol.74 , Issue.1 , pp. 8-12
    • Gibbons, R.D.1    Davis, J.M.2
  • 22
    • 0035890923 scopus 로고    scopus 로고
    • Aggressivity, suicide attempts, and depression: Relationship to cerebrospinal fluid monoamine metabolite levels
    • DOI 10.1016/S0006-3223(01)01170-2, PII S0006322301011702
    • Placidi GP, Oquendo MA, Malone KM, Huang YY, Ellis SP, Mann JJ. Aggressivity, suicide attempts, and depression: relationship to cerebrospinal fluid monoamine metabolite levels. Biol Psychiatry 2001; 50: 783-791. (Pubitemid 33086766)
    • (2001) Biological Psychiatry , vol.50 , Issue.10 , pp. 783-791
    • Placidi, G.P.A.1    Oquendo, M.A.2    Malone, K.M.3    Huang, Y.-Y.4    Ellis, S.P.5    Mann, J.J.6
  • 23
    • 0021889401 scopus 로고
    • Correlations between aminergic metabolites simultaneously obtained from human CSF and brain
    • DOI 10.1016/0024-3205(85)90242-5
    • Stanley M, Traskman-Bendz L, Dorovini-Zis K. Correlations between aminergic metabolites simultaneously obtained from human CSF and brain. Life Sci 1985; 37: 1279-1286. (Pubitemid 15013197)
    • (1985) Life Sciences , vol.37 , Issue.14 , pp. 1279-1286
    • Stanley, M.1    Traskman-Bendz, L.2    Dorovini-Zis, K.3
  • 25
    • 0025230323 scopus 로고
    • CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence
    • Brown GL, Linnoila MI. CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence. J Clin Psychiatry 1990; 51Suppl: 31-41, discussion 42-33. (Pubitemid 20134805)
    • (1990) Journal of Clinical Psychiatry , vol.51 , Issue.4 SUPPL. , pp. 31-41
    • Brown, G.L.1    Linnoila, M.I.2
  • 27
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • DOI 10.1016/0165-0270(85)90031-7
    • Pellow S, Chopin P, File SE, Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 1985; 14: 149-167. (Pubitemid 16239568)
    • (1985) Journal of Neuroscience Methods , vol.14 , Issue.3 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 28
    • 0025961370 scopus 로고
    • Evaluation of marble-Burying behavior as a model of anxiety
    • Njung'e K, Handley SL. Evaluation of marble-burying behavior as a model of anxiety. Pharmacol Biochem Behav 1991; 38: 63-67.
    • (1991) Pharmacol. Biochem. Behav. , vol.38 , pp. 63-67
    • Njung'e, K.1    Handley, S.L.2
  • 32
    • 28044463376 scopus 로고    scopus 로고
    • Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains
    • DOI 10.1111/j.1601-183X.2005.00145.x
    • Kulikov AV, Osipova DV, Naumenko VS, Popova NK. Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains. Genes Brain Behav 2005; 4: 482-485. (Pubitemid 41689393)
    • (2005) Genes, Brain and Behavior , vol.4 , Issue.8 , pp. 482-485
    • Kulikov, A.V.1    Osipova, D.V.2    Naumenko, V.S.3    Popova, N.K.4
  • 33
    • 0019434649 scopus 로고
    • Demonstration of tryptophan 5-monooxygenase activity in human brain by highly sensitive high-performance liquid chromatography with fluorometric detection
    • Yamaguchi T, Sawada M, Kato T, Nagatsu T. Demonstration of tryptophan 5- monooxygenase activity in human brain by high sensitive high-performance liquid chromatography with fluorometric detection. Biochem Int 1981; 2: 295-303. (Pubitemid 11121503)
    • (1981) Biochemistry International , vol.2 , Issue.3 , pp. 295-303
    • Yamaguchi, T.1    Sawada, M.2    Kato, T.3    Nagatsu, T.4
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 0001538535 scopus 로고
    • Evidence that serotonin has a role in brain function
    • Brodie BB, Pletscher A, Shore PA. Evidence that serotonin has a role in brain function. Science 1955; 122: 968.
    • (1955) Science , vol.122 , pp. 968
    • Brodie, B.B.1    Pletscher, A.2    Shore, P.A.3
  • 36
    • 67650591254 scopus 로고    scopus 로고
    • Monoaminergic neurotransmission: The history of the discovery of antidepressants from 1950s until today
    • Lopez-Munoz F, Alamo C. Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today. Curr Pharm Des 2009; 15: 1563-1586.
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 1563-1586
    • Lopez-Munoz, F.1    Alamo, C.2
  • 37
    • 0032031291 scopus 로고    scopus 로고
    • The neurobiology of tryptophan depletion in depression: Effects of intravenous tryptophan infusion
    • DOI 10.1016/S0006-3223(97)00284-9, PII S0006322397002849
    • Price LH, Malison RT, McDougle CJ, Pelton GH, Heninger GR. The neurobiology of tryptophan depletion in depression: effects of intravenous tryptophan infusion. Biol Psychiatry 1998; 43: 339-347. (Pubitemid 28137626)
    • (1998) Biological Psychiatry , vol.43 , Issue.5 , pp. 339-347
    • Price, L.H.1    Malison, R.T.2    McDougle, C.J.3    Pelton, G.H.4    Heninger, G.R.5
  • 38
    • 0020664741 scopus 로고
    • In search of the mode of action of antidepressants. 5-HTP/tyrosine mixtures in depressions
    • DOI 10.1016/0028-3908(83)90193-4
    • van Praag HM. In search of the mode of action of antidepressants. 5-HTP/tyrosine mixtures in depressions. Neuropharmacology 1983; 22: 433-440. (Pubitemid 13152055)
    • (1983) Neuropharmacology , vol.22 , Issue.3 B , pp. 433-440
    • Van Praag, H.M.1
  • 40
    • 0037389795 scopus 로고    scopus 로고
    • The effects of tryptophan depletion on mood and psychiatric symptoms
    • Schruers K, Griez E. The effects of tryptophan depletion on mood and psychiatric symptoms. J Affect Disord 2003; 74: 305.
    • (2003) J. Affect. Disord. , vol.74 , pp. 305
    • Schruers, K.1    Griez, E.2
  • 41
    • 79960063073 scopus 로고    scopus 로고
    • Animal models: Inside the minds of mice and men
    • Baker M. Animal models: inside the minds of mice and men. Nature 2011; 475: 123-128.
    • (2011) Nature , Issue.475 , pp. 123-128
    • Baker, M.1
  • 42
    • 2042546746 scopus 로고    scopus 로고
    • In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice
    • DOI 10.1038/sj.mp.4001457
    • Cryan JF, Mombereau C. In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice. Mol Psychiatry 2004; 9: 326-357. (Pubitemid 38534696)
    • (2004) Molecular Psychiatry , vol.9 , Issue.4 , pp. 326-357
    • Cryan, J.F.1    Mombereau, C.2
  • 43
    • 0024336510 scopus 로고
    • Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy
    • DOI 10.1016/0006-8993(89)90938-4
    • Drugan RC, Morrow AL, Weizman R, Weizman A, Deutsch SI, Crawley JN et al. Stressinduced behavioral depression in the rat is associated with a decrease in GABA receptormediated chloride ion flux and brain benzodiazepine receptor occupancy. Brain Res 1989; 87: 45-51. (Pubitemid 19135164)
    • (1989) Brain Research , vol.487 , Issue.1 , pp. 45-51
    • Drugan, R.C.1    Morrow, A.L.2    Weizman, R.3    Weizman, A.4    Deutsch, S.I.5    Crawley, J.N.6    Paul, S.M.7
  • 44
    • 33751188517 scopus 로고    scopus 로고
    • The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs
    • DOI 10.1016/j.euroneuro.2006.06.012, PII S0924977X06001258
    • O'Leary OF, Bechtholt AJ, Crowley JJ, Valentino RJ, Lucki I. The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs. Eur Neuropsychopharmacol 2007; 17: 215-226. (Pubitemid 44779196)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.3 , pp. 215-226
    • O'Leary, O.F.1    Bechtholt, A.J.2    Crowley, J.J.3    Valentino, R.J.4    Lucki, I.5
  • 46
    • 80054737715 scopus 로고    scopus 로고
    • Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: Neural and behavioral consequences
    • Narboux-Neme N, Sagne C, Doly S, Diaz SL, Martin CB, Angenard G et al. Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences. Neuropsychopharmacology 2011.
    • (2011) Neuropsychopharmacology
    • Narboux-Neme, N.1    Sagne, C.2    Doly, S.3    Diaz, S.L.4    Martin, C.B.5    Angenard, G.6
  • 47
    • 26044460006 scopus 로고    scopus 로고
    • Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety
    • DOI 10.1038/nrd1825, PII N1825
    • Cryan JF, Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 2005; 4: 775-790. (Pubitemid 43090498)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.9 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 48
    • 0035171425 scopus 로고    scopus 로고
    • Intra- and interstrain differences in models of "behavioral despair"
    • DOI 10.1016/S0091-3057(01)00599-8, PII S0091305701005998
    • Bai F, Li X, Clay M, Lindstrom T, Skolnick P. Intra- and interstrain differences in models of "behavioral despair". Pharmacol Biochem Behav 2001; 70: 187-192. (Pubitemid 33049928)
    • (2001) Pharmacology Biochemistry and Behavior , vol.70 , Issue.2-3 , pp. 187-192
    • Bai, F.1    Li, X.2    Clay, M.3    Lindstrom, T.4    Skolnick, P.5
  • 51
    • 34247872922 scopus 로고    scopus 로고
    • Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test
    • DOI 10.1007/s00213-007-0728-9
    • O'Leary OF, Bechtholt AJ, Crowley JJ, Hill TE, Page ME, Lucki I. Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test. Psychopharmacology 2007; 192: 357-371. (Pubitemid 46701581)
    • (2007) Psychopharmacology , vol.192 , Issue.3 , pp. 357-371
    • O'Leary, O.F.1    Bechtholt, A.J.2    Crowley, J.J.3    Hill, T.E.4    Page, M.E.5    Lucki, I.6
  • 52
    • 0031872388 scopus 로고    scopus 로고
    • Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test
    • DOI 10.1007/s002130050663
    • Redrobe JP, Bourin M. Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test. Psychopharmacology 1998; 138: 198-206. (Pubitemid 28330838)
    • (1998) Psychopharmacology , vol.138 , Issue.2 , pp. 198-206
    • Redrobe, J.P.1    Bourin, M.2
  • 53
    • 34548526653 scopus 로고    scopus 로고
    • Behavioral alteration in the adult rats prenatally exposed to para-chlorophenylalanine
    • DOI 10.1016/j.brainres.2007.06.056, PII S0006899307015454
    • Vataeva LA, Kudrin VS, Vershinina EA, Mosin VM, Tiul'kova EI, Otellin VA. Behavioral alteration in the adult rats prenatally exposed to para-chlorophenylalanine. Brain Res 2007; 1169: 9-16. (Pubitemid 47381353)
    • (2007) Brain Research , vol.1169 , Issue.1 , pp. 9-16
    • Vataeva, L.A.1    Kudrin, V.S.2    Vershinina, E.A.3    Mosin, V.M.4    Tiul'kova, E.I.5    Otellin, V.A.6
  • 54
    • 52249115611 scopus 로고    scopus 로고
    • Maternal parachlorophenylalanine exposure modifies central monoamines and behaviors in the adult offspring
    • Vataeva LA, Kudrin VS, Vershinina EA, Mosin VM, Tiul'kova EI, Otellin VA. Maternal parachlorophenylalanine exposure modifies central monoamines and behaviors in the adult offspring. Brain Res 2008; 1234: 1-7.
    • (2008) Brain Res. , vol.1234 , pp. 1-7
    • Vataeva, L.A.1    Kudrin, V.S.2    Vershinina, E.A.3    Mosin, V.M.4    Tiul'kova, E.I.5    Otellin, V.A.6
  • 55
    • 85046178415 scopus 로고
    • Neurochemical differences between two strains of mice
    • Maas JW. Neurochemical differences between two strains of mice. Science 1962; 137: 621-622.
    • (1962) Science , vol.137 , pp. 621-622
    • Maas, J.W.1
  • 56
  • 57
    • 0026760351 scopus 로고
    • Impulsive aggression and central serotonergic system function in humans: An example of a dimensional brain-behavior relationship
    • Coccaro EF. Impulsive aggression and central serotonergic system function in humans: an example of a dimensional brain-behavior relationship. Int Clin Psychopharmacol 1992; 7: 3-12.
    • (1992) Int. Clin. Psychopharmacol. , vol.7 , pp. 3-12
    • Coccaro, E.F.1
  • 58
    • 0030823201 scopus 로고    scopus 로고
    • Serotonin function and antiaggressive response to fluoxetine: A pilot study
    • DOI 10.1016/S0006-3223(97)00309-0, PII S0006322397003090
    • Coccaro EF, Kavoussi RJ, Hauger RL. Serotonin function and antiaggressive response to fluoxetine: a pilot study. Biol Psychiatry 1997; 42: 546-552. (Pubitemid 27425472)
    • (1997) Biological Psychiatry , vol.42 , Issue.7 , pp. 546-552
    • Coccaro, E.F.1    Kavoussi, R.J.2    Hauger, R.L.3
  • 60
    • 38649125257 scopus 로고    scopus 로고
    • Serotonergic functioning and trait-impulsivity in attention-deficit/ hyperactivity-disordered boys (ADHD): Influence of rapid tryptophan depletion
    • DOI 10.1002/hup.896
    • Zepf FD, Stadler C, Demisch L, Schmitt M, Landgraf M, Poustka F. Serotonergic functioning and trait-impulsivity in attention-deficit/ hyperactivity-disordered boys (ADHD): influence of rapid tryptophan depletion. Hum Psychopharmacol 2008; 23: 43-51. (Pubitemid 351166067)
    • (2008) Human Psychopharmacology , vol.23 , Issue.1 , pp. 43-51
    • Zepf, F.D.1    Stadler, C.2    Demisch, L.3    Schmitt, M.4    Landgraf, M.5    Poustka, F.6
  • 62
    • 70449533864 scopus 로고    scopus 로고
    • Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness
    • Schaefer TL, Vorhees CV, Williams MT. Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness. Neuroscience 2009; 164: 1431-1443.
    • (2009) Neuroscience , vol.164 , pp. 1431-1443
    • Schaefer, T.L.1    Vorhees, C.V.2    Williams, M.T.3
  • 64
    • 0037263673 scopus 로고    scopus 로고
    • Accumbal dopamine and serotonin in anticipation of the next aggressive episode in rats
    • DOI 10.1046/j.1460-9568.2003.02447.x
    • Ferrari PF, van Erp AM, Tornatzky W, Miczek KA. Accumbal dopamine and serotonin in anticipation of the next aggressive episode in rats. Eur J Neurosci 2003; 17: 371-378. (Pubitemid 36459517)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.2 , pp. 371-378
    • Ferrari, P.F.1    Van Erp, A.M.M.2    Tornatzky, W.3    Miczek, K.A.4
  • 65
    • 0034671196 scopus 로고    scopus 로고
    • Aggressive behavior, increased accumbal dopamine, and decreased cortical serotonin in rats
    • van Erp AM, Miczek KA. Aggressive behavior, increased accumbal dopamine, and decreased cortical serotonin in rats. J Neurosci 2000; 20: 9320-9325. (Pubitemid 32042936)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9320-9325
    • Van Erp, A.M.M.1    Miczek, K.A.2
  • 66
    • 0032145210 scopus 로고    scopus 로고
    • The spectrum of behaviors influenced by serotonin
    • DOI 10.1016/S0006-3223(98)00139-5, PII S0006322398001395
    • Lucki I. The spectrum of behaviors influenced by serotonin. Biol Psychiatry 1998; 44: 151-162. (Pubitemid 28378297)
    • (1998) Biological Psychiatry , vol.44 , Issue.3 , pp. 151-162
    • Lucki, I.1
  • 68
    • 0015505990 scopus 로고
    • Benzodiazepines: Anxiety-Reducing activity by reduction of serotonin turnover in the brain
    • Wise CD, Berger BD, Stein L. Benzodiazepines: anxiety-reducing activity by reduction of serotonin turnover in the brain. Science 1972; 177: 180-183.
    • (1972) Science , vol.177 , pp. 180-183
    • Wise, C.D.1    Berger, B.D.2    Stein, L.3
  • 69
    • 3042640899 scopus 로고    scopus 로고
    • Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze
    • DOI 10.1016/j.bbr.2003.10.036, PII S0166432803004194
    • Andrade TG, Macedo CE, Zangrossi Jr H, Graeff FG. Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze. Behav Brain Res 2004; 153: 55-60. (Pubitemid 38829288)
    • (2004) Behavioural Brain Research , vol.153 , Issue.1 , pp. 55-60
    • Andrade, T.G.C.S.1    Macedo, C.E.A.2    Zangrossi Jr., H.3    Graeff, F.G.4
  • 70
    • 0025267002 scopus 로고
    • Effect of serotonergic lesion on 'anxious' behaviour measured in the elevated plus-maze test in the rat
    • Briley M, Chopin P, Moret C. Effect of serotonergic lesion on "anxious" behaviour measured in the elevated plus-maze test in the rat. Psychopharmacology 1990; 101: 187-189. (Pubitemid 20140216)
    • (1990) Psychopharmacology , vol.101 , Issue.2 , pp. 187-189
    • Briley, M.1    Chopin, P.2    Moret, C.3
  • 71
    • 0026500998 scopus 로고
    • Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions
    • Critchley MA, Njung'e K, Handley SL. Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions. Psychopharmacology 1992; 106: 484-490.
    • (1992) Psychopharmacology , vol.106 , pp. 484-490
    • Critchley, M.A.1    Njung'e, K.2    Handley, S.L.3
  • 73
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
    • DOI 10.1126/science.1101678
    • Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 2004; 306: 879-881. (Pubitemid 39446998)
    • (2004) Science , vol.306 , Issue.5697 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3    Hen, R.4    Gingrich, J.A.5
  • 74
    • 0345305849 scopus 로고    scopus 로고
    • Abnormal anxiety-related behavior in serotonin transporter null mutant mice: The influence of genetic background
    • DOI 10.1046/j.1601-1848.2003.00050.x
    • Holmes A, Lit Q, Murphy DL, Gold E, Crawley JN. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes Brain Behav 2003; 2: 365-380. (Pubitemid 37463201)
    • (2003) Genes, Brain and Behavior , vol.2 , Issue.6 , pp. 365-380
    • Holmes, A.1    Li, Q.2    Murphy, D.L.3    Gold, E.4    Crawley, J.N.5
  • 76
    • 0037187193 scopus 로고    scopus 로고
    • 1A receptor acts during development to establish normal anxiety-like behaviour in the adult
    • DOI 10.1038/416396a
    • Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L et al. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 2002; 416: 396-400. (Pubitemid 34272867)
    • (2002) Nature , vol.416 , Issue.6879 , pp. 396-400
    • Gross, C.1    Zhuang, X.2    Stark, K.3    Ramboz, S.4    Oosting, R.5    Kirby, L.6    Santarelli, L.7    Beck, S.8    Hen, R.9
  • 78
    • 79951993063 scopus 로고    scopus 로고
    • A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei
    • Kiyasova V, Fernandez SP, Laine J, Stankovski L, Muzerelle A, Doly S et al. A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei. J Neurosci 2011; 31: 2756-2768.
    • (2011) J. Neurosci. , vol.31 , pp. 2756-2768
    • Kiyasova, V.1    Fernandez, S.P.2    Laine, J.3    Stankovski, L.4    Muzerelle, A.5    Doly, S.6
  • 79
    • 33646379343 scopus 로고    scopus 로고
    • Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice
    • DOI 10.1016/j.neuroscience.2006.01.049, PII S0306452206001424
    • Zhao S, Edwards J, Carroll J, Wiedholz L, Millstein RA, Jaing C et al. Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotionrelated behaviors in mice. Neuroscience 2006; 140: 321-334. (Pubitemid 43668455)
    • (2006) Neuroscience , vol.140 , Issue.1 , pp. 321-334
    • Zhao, S.1    Edwards, J.2    Carroll, J.3    Wiedholz, L.4    Millstein, R.A.5    Jaing, C.6    Murphy, D.L.7    Lanthorn, T.H.8    Holmes, A.9
  • 81
    • 0015216394 scopus 로고
    • Brain serotonin content: Physiological dependence on plasma tryptophan levels
    • Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological dependence on plasma tryptophan levels. Science 1971; 173: 149-152.
    • (1971) Science , vol.173 , pp. 149-152
    • Fernstrom, J.D.1    Wurtman, R.J.2
  • 82
    • 54049124260 scopus 로고    scopus 로고
    • Dietary amino acids and brain serotonin function; implications for stressrelated affective changes
    • Markus CR. Dietary amino acids and brain serotonin function; implications for stressrelated affective changes. Neuromolecular Med 2008; 10: 247-258.
    • (2008) Neuromolecular. Med. , vol.10 , pp. 247-258
    • Markus, C.R.1
  • 83
    • 77955090863 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice
    • Siesser WB, Zhang X, Jacobsen JP, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. Neurosci Lett 2010; 481: 6-11.
    • (2010) Neurosci. Lett. , vol.481 , pp. 6-11
    • Siesser, W.B.1    Zhang, X.2    Jacobsen, J.P.3    Sotnikova, T.D.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 84
    • 38049004434 scopus 로고    scopus 로고
    • The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains
    • Tenner K, Qadri F, Bert B, Voigt JP, Bader M. The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains. Neurosci Lett 2008; 431: 21-25.
    • (2008) Neurosci. Lett. , vol.431 , pp. 21-25
    • Tenner, K.1    Qadri, F.2    Bert, B.3    Voigt, J.P.4    Bader, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.