Influenza A virus polymerase is a site for adaptive changes during experimental evolution in bat cells

Journal of Virology

Volumn 88, Issue 21, 2014, Pages 12572-12585

  Poole, Daniel S ^a   Yú, Shuĭqìng ^b   Caì, Yíngyún ^b   Dinis, Jorge M ^c   Müller, Marcel A ^d   Jordan, Ingo ^e   Friedrich, Thomas C ^c,f   Kuhn, Jens H ^b   Mehle, Andrew ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF BONN   (Germany)

^e PROBIOGEN AG   (Germany)

^f UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR; RIBONUCLEOPROTEIN; SIALIC ACID RECEPTOR; UNCLASSIFIED DRUG; VIRUS HEMAGGLUTININ; PA PROTEIN, INFLUENZA VIRUSES; PB2 PROTEIN, INFLUENZAVIRUS A; RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BAT; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; E627K GENE; EMBRYO; GENE EXPRESSION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; INFECTION SENSITIVITY; INFLUENZA A; INFLUENZA VIRUS A; M285K GENE; NONHUMAN; PHYLOGENY; PROTEIN EXPRESSION; VIRAL TROPISM; VIRUS ENTRY; VIRUS GENE; VIRUS REPLICATION; VIRUS TITRATION; VIRUS TRANSMISSION; ADAPTATION; ANIMAL; CELL LINE; ENZYMOLOGY; GENETICS; HIGH THROUGHPUT SEQUENCING; INFLUENZA A VIRUS; METABOLISM; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ADAPTATION, BIOLOGICAL; ANIMALS; CELL LINE; CHIROPTERA; CYTOPATHOGENIC EFFECT, VIRAL; DNA MUTATIONAL ANALYSIS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; INFLUENZA A VIRUS; MUTATION, MISSENSE; RNA REPLICASE; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84907978081     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01857-14     Document Type: Article

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