메뉴 건너뛰기




Volumn 178, Issue 4, 2007, Pages 2148-2154

Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-κB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; COLONY STIMULATING FACTOR 1; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN TRAM; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG;

EID: 33846932789     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.4.2148     Document Type: Article
Times cited : (34)

References (44)
  • 1
    • 0037427976 scopus 로고    scopus 로고
    • Toll-like receptors linking innate and adaptive immune response
    • Werling, D., and T. W. Jungi. 2003. Toll-like receptors linking innate and adaptive immune response. Vet. Immunol. Immunopathol. 91: 1-12.
    • (2003) Vet. Immunol. Immunopathol , vol.91 , pp. 1-12
    • Werling, D.1    Jungi, T.W.2
  • 2
    • 0038182550 scopus 로고    scopus 로고
    • Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide- binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved
    • Schroder, N. W., S. Morath, C. Alexander, L. Hamann, T. Hartung, U. Zahringer, U. B. Gobel, J. R. Weber, and R. R. Schumann. 2003. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide- binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved. J. Biol. Chem. 278: 15587-15594.
    • (2003) J. Biol. Chem , vol.278 , pp. 15587-15594
    • Schroder, N.W.1    Morath, S.2    Alexander, C.3    Hamann, L.4    Hartung, T.5    Zahringer, U.6    Gobel, U.B.7    Weber, J.R.8    Schumann, R.R.9
  • 3
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274: 10689-10692.
    • (1999) J. Biol. Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 4
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 8
    • 0031423761 scopus 로고    scopus 로고
    • MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., W. J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7: 837-847.
    • (1997) Immunity , vol.7 , pp. 837-847
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 9
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • Zhang, F. X., C. J. Kirschning, R. Mancinelli, X. P. Xu, Y. Jin, E. Faure, A. Mantovani, M. Rothe, M. Muzio, and M. Arditi. 1999. Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274: 7611-7614.
    • (1999) J. Biol. Chem , vol.274 , pp. 7611-7614
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3    Xu, X.P.4    Jin, Y.5    Faure, E.6    Mantovani, A.7    Rothe, M.8    Muzio, M.9    Arditi, M.10
  • 11
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng, T., G. M. Barton, and R. Medzhitov. 2001. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2: 835-841.
    • (2001) Nat. Immunol , vol.2 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 12
    • 0037114185 scopus 로고    scopus 로고
    • Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
    • Yamamoto, M., S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J. Immmol. 169: 6668-6672.
    • (2002) J. Immmol , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7
  • 13
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
    • Oshiumi, H., M. Matsumoto, K. Funami, T. Akazawa, and T. Seya. 2003. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction. Nat. Immunol. 4: 161-167.
    • (2003) Nat. Immunol , vol.4 , pp. 161-167
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 15
    • 0042591216 scopus 로고    scopus 로고
    • TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
    • Bin, L. H., L. G. Xu, and H. B. Shu. 2003. TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J. Biol. Chem. 278: 24526-24532.
    • (2003) J. Biol. Chem , vol.278 , pp. 24526-24532
    • Bin, L.H.1    Xu, L.G.2    Shu, H.B.3
  • 16
    • 0345991221 scopus 로고    scopus 로고
    • TICACM-2: A bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β
    • Oshiumi, H., M. Sasai, K. Shida, T. Fujita, M. Matsumoto, and T. Seya. 2003. TICACM-2: a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β. J. Biol. Chem. 278: 49751-49762.
    • (2003) J. Biol. Chem , vol.278 , pp. 49751-49762
    • Oshiumi, H.1    Sasai, M.2    Shida, K.3    Fujita, T.4    Matsumoto, M.5    Seya, T.6
  • 17
    • 0035367786 scopus 로고    scopus 로고
    • A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
    • Mink, M., B. Fogelgren, K. Olszewski, P. Maroy, and K. Csiszar. 2001. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74: 234-244.
    • (2001) Genomics , vol.74 , pp. 234-244
    • Mink, M.1    Fogelgren, B.2    Olszewski, K.3    Maroy, P.4    Csiszar, K.5
  • 18
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda, K., and S. Akira. 2005. Toll-like receptors in innate immunity. Int. Immunol. 17: 1-14.
    • (2005) Int. Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 23
    • 1542373649 scopus 로고    scopus 로고
    • Distinct pathways of LPS-induced NF-κB activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP
    • Andreakos, E., S. M. Sacre, C. Smith, A. Lundberg, S. Kiriakidis, T. Stonehouse, C. Monaco, M. Feldmann, and B. M. Foxwell. 2004. Distinct pathways of LPS-induced NF-κB activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Blood 103: 2229-2237.
    • (2004) Blood , vol.103 , pp. 2229-2237
    • Andreakos, E.1    Sacre, S.M.2    Smith, C.3    Lundberg, A.4    Kiriakidis, S.5    Stonehouse, T.6    Monaco, C.7    Feldmann, M.8    Foxwell, B.M.9
  • 24
    • 0345991221 scopus 로고    scopus 로고
    • TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β
    • Oshiumi, H., M. Sasai, K. Shida, T. Fujita, M. Matsumoto, and T. Seya. 2003. TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β. J. Biol. Chem. 278: 49751-49762.
    • (2003) J. Biol. Chem , vol.278 , pp. 49751-49762
    • Oshiumi, H.1    Sasai, M.2    Shida, K.3    Fujita, T.4    Matsumoto, M.5    Seya, T.6
  • 25
    • 14044251499 scopus 로고    scopus 로고
    • Transforming growth factor-β differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling
    • Naiki, Y., K. S. Michelsen, W. Zhang, S. Chen, T. M. Doherty, and M. Arditi. 2005. Transforming growth factor-β differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling. J. Biol. Chem. 280: 5491-5495.
    • (2005) J. Biol. Chem , vol.280 , pp. 5491-5495
    • Naiki, Y.1    Michelsen, K.S.2    Zhang, W.3    Chen, S.4    Doherty, T.M.5    Arditi, M.6
  • 26
    • 0028170653 scopus 로고
    • p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts
    • Butler, D. M., M. Feldmann, F. Di Padova, and F. M. Brennan. 1994. p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts. Eur. Cytokine Netw. 5: 441-448.
    • (1994) Eur. Cytokine Netw , vol.5 , pp. 441-448
    • Butler, D.M.1    Feldmann, M.2    Di Padova, F.3    Brennan, F.M.4
  • 27
    • 0032493278 scopus 로고    scopus 로고
    • Efficient adenoviral infection with IκB α reveals that macrophage tumor necrosis factor α production in rheumatoid arthritis is NF-κB dependent
    • Foxwell, B., K. Browne, J. Bondeson, C. Clarke, R. de Martin, F. Brennan, and M. Feldmann. 1998. Efficient adenoviral infection with IκB α reveals that macrophage tumor necrosis factor α production in rheumatoid arthritis is NF-κB dependent. Proc. Natl. Acad. Sci. USA 95: 8211-8215.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8211-8215
    • Foxwell, B.1    Browne, K.2    Bondeson, J.3    Clarke, C.4    de Martin, R.5    Brennan, F.6    Feldmann, M.7
  • 28
    • 0023773031 scopus 로고
    • Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-1α
    • Buchan, G., K. Barrett, M. Turner, D. Chantry, R. N. Maini, and M. Feldmann. 1988. Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1α. Clin. Exp. Immunol. 73: 449-455.
    • (1988) Clin. Exp. Immunol , vol.73 , pp. 449-455
    • Buchan, G.1    Barrett, K.2    Turner, M.3    Chantry, D.4    Maini, R.N.5    Feldmann, M.6
  • 29
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins: Identification by morphologic and immunologic criteria
    • Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1973. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest. 52: 2745-2756.
    • (1973) J. Clin. Invest , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 31
    • 0029315806 scopus 로고
    • Methods for construction of adenovirus vectors
    • Graham, F. L., and L. Prevec. 1995. Methods for construction of adenovirus vectors. Mol. Biotechnol. 3: 207-220.
    • (1995) Mol. Biotechnol , vol.3 , pp. 207-220
    • Graham, F.L.1    Prevec, L.2
  • 32
    • 0033041954 scopus 로고    scopus 로고
    • Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro
    • Aoki, K., C. Barker, X. Danthinne, M. J. Imperiale, and G. J. Nabel. 1999. Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro. Mol. Med. 5: 224-231,
    • (1999) Mol. Med , vol.5 , pp. 224-231
    • Aoki, K.1    Barker, C.2    Danthinne, X.3    Imperiale, M.J.4    Nabel, G.J.5
  • 34
    • 0026529289 scopus 로고
    • Identification of novel factors that bind to the PRD I region of the human β-interferon promoter
    • Whiteside, S. T., K. V. Visvanathan, and S. Goodbourn. 1992. Identification of novel factors that bind to the PRD I region of the human β-interferon promoter. Nucleic Acids Res. 20: 1531-1538.
    • (1992) Nucleic Acids Res , vol.20 , pp. 1531-1538
    • Whiteside, S.T.1    Visvanathan, K.V.2    Goodbourn, S.3
  • 35
    • 0028970549 scopus 로고
    • Interleukin-4 inhibits κ light chain expression and NF κB activation but not IκBα degradation in 70Z/3 murine pre-B cells
    • Clarke, C. J., D. A. Taylor-Fishwick, A. Hales, Y. Chernajovsky, K. Sugamura, M. Feldmann, and B. M. Foxwell. 1995. Interleukin-4 inhibits κ light chain expression and NF κB activation but not IκBα degradation in 70Z/3 murine pre-B cells. Eur. J. Immunol. 25: 2961-2966.
    • (1995) Eur. J. Immunol , vol.25 , pp. 2961-2966
    • Clarke, C.J.1    Taylor-Fishwick, D.A.2    Hales, A.3    Chernajovsky, Y.4    Sugamura, K.5    Feldmann, M.6    Foxwell, B.M.7
  • 36
    • 0000631035 scopus 로고
    • The Role of endotoxin in the extracellular coagulation of limulus blood
    • Levin, J., and F. B. Bang. 1964. The Role of endotoxin in the extracellular coagulation of limulus blood. Bull. Johns Hopkins Hosp. 115: 265-274.
    • (1964) Bull. Johns Hopkins Hosp , vol.115 , pp. 265-274
    • Levin, J.1    Bang, F.B.2
  • 37
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65: 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 39
    • 0242391978 scopus 로고    scopus 로고
    • Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-γ and provide a mechanism for enhanced synovial chemokine levels in septic arthritis
    • Proost, P., A. K. Vynckier, F. Mahieu, W. Put, B. Grillet, S. Struyf, A. Wuyts, G. Opdenakker, and J. Van Damme. 2003. Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-γ and provide a mechanism for enhanced synovial chemokine levels in septic arthritis. Eur. J. Immunol. 33: 3146-3153.
    • (2003) Eur. J. Immunol , vol.33 , pp. 3146-3153
    • Proost, P.1    Vynckier, A.K.2    Mahieu, F.3    Put, W.4    Grillet, B.5    Struyf, S.6    Wuyts, A.7    Opdenakker, G.8    Van Damme, J.9
  • 41
    • 0036202847 scopus 로고    scopus 로고
    • Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS
    • Vitravene Study Group
    • Vitravene Study Group. 2002. Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS. Am. J. Ophthalmol. 133: 484-498.
    • (2002) Am. J. Ophthalmol , vol.133 , pp. 484-498
  • 43
    • 27444431760 scopus 로고    scopus 로고
    • Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88
    • Ding, A., H. Yu, J. Yang, S. Shi, and S. Ehrt. 2005. Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88. Immunology 116: 381-389.
    • (2005) Immunology , vol.116 , pp. 381-389
    • Ding, A.1    Yu, H.2    Yang, J.3    Shi, S.4    Ehrt, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.