메뉴 건너뛰기




Volumn 146, Issue 4, 2014, Pages 1123-1130

Anthracycline-dependent cardiotoxicity and extracellular matrix remodeling

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DAUNORUBICIN; DOXORUBICIN; REACTIVE OXYGEN METABOLITE; ANTHRACYCLINE; ANTINEOPLASTIC ANTIBIOTIC;

EID: 84907924789     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.14-0460     Document Type: Article
Times cited : (31)

References (71)
  • 1
    • 74049097142 scopus 로고    scopus 로고
    • Cardiotoxicity of anticancer drugs: The need for cardio-oncology and cardio-oncological prevention
    • Albini A, Pennesi G, Donatelli F, Cammarota R, De Flora S, Noonan DM. Cardiotoxicity of anticancer drugs: The need for cardio-oncology and cardio-oncological prevention. J Natl Cancer Inst. 2010; 102 ( 1 ): 14 - 25.
    • (2010) J Natl Cancer Inst , vol.102 , Issue.1 , pp. 14-25
    • Albini, A.1    Pennesi, G.2    Donatelli, F.3    Cammarota, R.4    De Flora, S.5    Noonan, D.M.6
  • 2
    • 0000097143 scopus 로고
    • Anthracyclinones and anthracyclines (rhodomycinone, pyrromycinone and their glycosides)
    • [in German]
    • Brockmann H. Anthracyclinones and anthracyclines. (Rhodomycinone, pyrromycinone and their glycosides) [in German]. Fortschr Chem Org Naturst. 1963; 21 : 121 - 182.
    • (1963) Fortschr Chem Org Naturst. , vol.21 , pp. 121-182
    • Brockmann, H.1
  • 3
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev. 2004; 56 ( 2 ): 185 - 229.
    • (2004) Pharmacol Rev , vol.56 , Issue.2 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 4
    • 33644685056 scopus 로고    scopus 로고
    • Correlation of plasma N-terminal pro-brain natriuretic peptide levels with left ventricle mass in children treated with anthracyclines
    • Germanakis I, Kalmanti M, Parthenakis F, et al. Correlation of plasma N-terminal pro-brain natriuretic peptide levels with left ventricle mass in children treated with anthracyclines. Int J Cardiol. 2006; 108 ( 2 ): 212 - 215.
    • (2006) Int J Cardiol , vol.108 , Issue.2 , pp. 212-215
    • Germanakis, I.1    Kalmanti, M.2    Parthenakis, F.3
  • 5
    • 0020356720 scopus 로고
    • Membrane transport of anthracyclines
    • Skovsgaard T, Nissen NI. Membrane transport of anthracyclines. Pharmacol Ther. 1982; 18 ( 3 ): 293 - 311.
    • (1982) Pharmacol Ther , vol.18 , Issue.3 , pp. 293-311
    • Skovsgaard, T.1    Nissen, N.I.2
  • 6
    • 0035866817 scopus 로고    scopus 로고
    • Mechanism of specific nuclear transport of adriamycin: The mode of nuclear translocation of adriamycin- proteasome complex
    • Kiyomiya K, Matsuo S, Kurebe M. Mechanism of specifi c nuclear transport of adriamycin: The mode of nuclear translocation of adriamycin- proteasome complex. Cancer Res. 2001; 61 ( 6 ): 2467 - 2471.
    • (2001) Cancer Res , vol.61 , Issue.6 , pp. 2467-2471
    • Kiyomiya, K.1    Matsuo, S.2    Kurebe, M.3
  • 7
    • 0025115736 scopus 로고
    • Abnormally high expression of proteasomes in human leukemic cells
    • Kumatori A, Tanaka K, Inamura N, et al. Abnormally high expression of proteasomes in human leukemic cells. Proc Natl Acad Sci U S A. 1990; 87 ( 18 ): 7071 - 7075.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.18 , pp. 7071-7075
    • Kumatori, A.1    Tanaka, K.2    Inamura, N.3
  • 8
    • 0027518334 scopus 로고
    • Changes in intracellular localization of proteasomes in immortalized ovarian granulosa cells during mitosis associated with a role in cell cycle control
    • Amsterdam A, Pitzer F, Baumeister W. Changes in intracellular localization of proteasomes in immortalized ovarian granulosa cells during mitosis associated with a role in cell cycle control. Proc Natl Acad Sci U S A. 1993; 90 ( 1 ): 99 - 103.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.1 , pp. 99-103
    • Amsterdam, A.1    Pitzer, F.2    Baumeister, W.3
  • 9
    • 0016640250 scopus 로고
    • DNA complexing antibiotics: Daunomycin, adriamycin and their derivatives
    • Marco A, Arcamone F. DNA complexing antibiotics: daunomycin, adriamycin and their derivatives. Arzneimittelforschung. 1975; 25 ( 3 ): 368 - 374.
    • (1975) Arzneimittelforschung , vol.25 , Issue.3 , pp. 368-374
    • Marco, A.1    Arcamone, F.2
  • 10
    • 0038640518 scopus 로고
    • Selective displacement of nuclear proteins by antitumor drugs having affinity for nucleic acids
    • Bartkowiak J, Kapuscinski J, Melamed MR, Darzynkiewicz Z. Selective displacement of nuclear proteins by antitumor drugs having affi nity for nucleic acids. Proc Natl Acad Sci U S A. 1989; 86 ( 13 ): 5151 - 5154.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , Issue.13 , pp. 5151-5154
    • Bartkowiak, J.1    Kapuscinski, J.2    Melamed, M.R.3    Darzynkiewicz, Z.4
  • 11
    • 0033603302 scopus 로고    scopus 로고
    • Daunomycin-induced unfolding and aggregation of chromatin
    • Rabbani A, Iskandar M, Ausio J. Daunomycin-induced unfolding and aggregation of chromatin. J Biol Chem. 1999; 274( 26): 18401- 18406.
    • (1999) J Biol Chem. , vol.274 , Issue.26 , pp. 18401-18406
    • Rabbani, A.1    Iskandar, M.2    Ausio, J.3
  • 12
    • 0028236628 scopus 로고
    • Effects of anthracycline antibiotic, daunomycin on thymus chromatin: The role of chromosomal proteins
    • Rabbani A, Davoodi J. Effects of anthracycline antibiotic, daunomycin on thymus chromatin: The role of chromosomal proteins. Gen Pharmacol. 1994; 25 ( 4 ): 787 - 793.
    • (1994) Gen Pharmacol , vol.25 , Issue.4 , pp. 787-793
    • Rabbani, A.1    Davoodi, J.2
  • 13
    • 45849085448 scopus 로고    scopus 로고
    • Sp1 transcription factor as a target for anthracyclines: Effects on gene transcription
    • Mansilla S, Portugal J. Sp1 transcription factor as a target for anthracyclines: effects on gene transcription. Biochimie. 2008; 90 ( 7 ): 976 - 987.
    • (2008) Biochimie , vol.90 , Issue.7 , pp. 976-987
    • Mansilla, S.1    Portugal, J.2
  • 14
    • 0035210230 scopus 로고    scopus 로고
    • Inhibition of RNA synthesis in vitro and cell growth by anthracycline antibiotics
    • Studzian K, Wasowska M, Piestrzeniewicz MK, et al. Inhibition of RNA synthesis in vitro and cell growth by anthracycline antibiotics. Neoplasma. 2001; 48 ( 5 ): 412 - 418.
    • (2001) Neoplasma , vol.48 , Issue.5 , pp. 412-418
    • Studzian, K.1    Wasowska, M.2    Piestrzeniewicz, M.K.3
  • 15
    • 0035041124 scopus 로고    scopus 로고
    • Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines
    • Perego P, Corna E, De Cesare M, et al. Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines. Curr Med Chem. 2001; 8 ( 1 ): 31 - 37.
    • (2001) Curr Med Chem. , vol.8 , Issue.1 , pp. 31-37
    • Perego, P.1    Corna, E.2    De Cesare, M.3
  • 16
    • 0037048710 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis
    • Green PS, Leeuwenburgh C. Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis. Biochim Biophys Acta. 2002; 1588 ( 1 ): 94 - 101.
    • (2002) Biochim Biophys Acta , vol.1588 , Issue.1 , pp. 94-101
    • Green, P.S.1    Leeuwenburgh, C.2
  • 17
    • 0032737882 scopus 로고    scopus 로고
    • MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes
    • Zhu W, Zou Y, Aikawa R, et al. MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes. Circulation. 1999; 100 ( 20 ): 2100 - 2107.
    • (1999) Circulation , vol.100 , Issue.20 , pp. 2100-2107
    • Zhu, W.1    Zou, Y.2    Aikawa, R.3
  • 18
    • 0030804864 scopus 로고    scopus 로고
    • Analyses of the molecular mechanism of adriamycin- induced cardiotoxicity
    • Gille L, Nohl H. Analyses of the molecular mechanism of adriamycin- induced cardiotoxicity. Free Radic Biol Med. 1997; 23 ( 5 ): 775 - 782.
    • (1997) Free Radic Biol Med. , vol.23 , Issue.5 , pp. 775-782
    • Gille, L.1    Nohl, H.2
  • 19
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med. 1998; 339 ( 13 ): 900 - 905.
    • (1998) N Engl J Med. , vol.339 , Issue.13 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 20
    • 84883592712 scopus 로고    scopus 로고
    • Emerging paradigms in cardiomyopathies associated with cancer therapies
    • Ky B, Vejpongsa P, Yeh ET, Force T, Moslehi JJ. Emerging paradigms in cardiomyopathies associated with cancer therapies. Circ Res. 2013; 113 ( 6 ): 754 - 764.
    • (2013) Circ Res. , vol.113 , Issue.6 , pp. 754-764
    • Ky, B.1    Vejpongsa, P.2    Yeh, E.T.3    Force, T.4    Moslehi, J.J.5
  • 21
    • 6044274062 scopus 로고    scopus 로고
    • Cardiovascular complications of cancer therapy: Diagnosis, pathogenesis, and management
    • Yeh ET, Tong AT, Lenihan DJ, et al. Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation. 2004; 109 ( 25 ): 3122 - 3131.
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3122-3131
    • Yeh, E.T.1    Tong, A.T.2    Lenihan, D.J.3
  • 22
    • 33746840071 scopus 로고    scopus 로고
    • Heart failure induced by non-cardiac drugs
    • Slordal L, Spigset O. Heart failure induced by non-cardiac drugs. Drug Saf. 2006; 29 ( 7 ): 567 - 586.
    • (2006) Drug Saf , vol.29 , Issue.7 , pp. 567-586
    • Slordal, L.1    Spigset, O.2
  • 23
    • 0017656527 scopus 로고
    • Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response
    • Myers CE, McGuire WP, Liss RH, Ifrim I, Grotzinger K, Young RC. Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response. Science. 1977; 197 ( 4299 ): 165 - 167.
    • (1977) Science , vol.197 , Issue.4299 , pp. 165-167
    • Myers, C.E.1    McGuire, W.P.2    Liss, R.H.3    Ifrim, I.4    Grotzinger, K.5    Young, R.C.6
  • 24
    • 33947128057 scopus 로고    scopus 로고
    • Adriamycin-induced myocardial toxicity: New solutions for an old problem?
    • Outomuro D, Grana DR, Azzato F, Milei J. Adriamycin-induced myocardial toxicity: New solutions for an old problem? Int J Cardiol. 2007; 117 ( 1 ): 6 - 15.
    • (2007) Int J Cardiol. , vol.117 , Issue.1 , pp. 6-15
    • Outomuro, D.1    Grana, D.R.2    Azzato, F.3    Milei, J.4
  • 25
    • 84888843756 scopus 로고    scopus 로고
    • Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants
    • Juranek I, Nikitovic D, Kouretas D, Hayes AW, Tsatsakis AM. Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants. Food Chem Toxicol. 2013; 61 : 240 - 247.
    • (2013) Food Chem Toxicol. , vol.61 , pp. 240-247
    • Juranek, I.1    Nikitovic, D.2    Kouretas, D.3    Hayes, A.W.4    Tsatsakis, A.M.5
  • 27
    • 84888820105 scopus 로고    scopus 로고
    • Role of oxidative stress in chemical allergens induced skin cells activation
    • Corsini E, Galbiati V, Nikitovic D, Tsatsakis AM. Role of oxidative stress in chemical allergens induced skin cells activation. Food Chem Toxicol. 2013; 61 : 74 - 81.
    • (2013) Food Chem Toxicol. , vol.61 , pp. 74-81
    • Corsini, E.1    Galbiati, V.2    Nikitovic, D.3    Tsatsakis, A.M.4
  • 28
    • 33646519886 scopus 로고    scopus 로고
    • Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity
    • Dong F, Fang CX, Yang X, Zhang X, Lopez FL, Ren J. Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: role of oxidative stress, protein carbonyl formation and insulin sensitivity. Diabetologia. 2006; 49 ( 6 ): 1421 - 1433.
    • (2006) Diabetologia , vol.49 , Issue.6 , pp. 1421-1433
    • Dong, F.1    Fang, C.X.2    Yang, X.3    Zhang, X.4    Lopez, F.L.5    Ren, J.6
  • 29
    • 0036285309 scopus 로고    scopus 로고
    • Predicting cancer therapyinduced cardiotoxicity: The role of troponins and other markers
    • Sparano JA, Brown DL, Wolff AC. Predicting cancer therapyinduced cardiotoxicity: The role of troponins and other markers. Drug Saf. 2002; 25 ( 5 ): 301 - 311.
    • (2002) Drug Saf. , vol.25 , Issue.5 , pp. 301-311
    • Sparano, J.A.1    Brown, D.L.2    Wolff, A.C.3
  • 30
    • 0026337024 scopus 로고
    • Binding of doxorubicin to cardiolipin as compared to other anionic phospholipids-an evaluation of electrostatic effects
    • de Wolf, FA. Binding of doxorubicin to cardiolipin as compared to other anionic phospholipids-an evaluation of electrostatic effects. Biosci Rep. 1991; 11 ( 5 ): 275 - 284.
    • (1991) Biosci Rep. , vol.11 , Issue.5 , pp. 275-284
    • De Wolf, F.A.1
  • 31
    • 0242442100 scopus 로고    scopus 로고
    • Time-dependent and tissue-specific accumulation of MT DNA and respiratory chain defects in chronic doxorubicin cardiomyopathy
    • Lebrecht D, Setzer B, Ketelsen UP, Haberstroh J, Walker UA. Time-dependent and tissue-specific accumulation of mt DNA and respiratory chain defects in chronic doxorubicin cardiomyopathy. Circulation. 2003; 108 ( 19 ): 2423 - 2429.
    • (2003) Circulation , vol.108 , Issue.19 , pp. 2423-2429
    • Lebrecht, D.1    Setzer, B.2    Ketelsen, U.P.3    Haberstroh, J.4    Walker, U.A.5
  • 32
    • 0041304980 scopus 로고    scopus 로고
    • Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria
    • Clementi ME, Giardina B, Di Stasio E, Mordente A, Misiti F. Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria. Anticancer Res. 2003; 23 ( 3B ): 2445 - 2450.
    • (2003) Anticancer Res. , vol.23 , Issue.3 B , pp. 2445-2450
    • Clementi, M.E.1    Giardina, B.2    Di Stasio, E.3    Mordente, A.4    Misiti, F.5
  • 33
    • 0031845978 scopus 로고    scopus 로고
    • Doxorubicin cardiotoxicity: Diastolic cardiac myocyte dysfunction as a result of impaired calcium handling in isolated cardiac myocytes
    • Maeda A, Honda M, Kuramochi T, Takabatake T. Doxorubicin cardiotoxicity: diastolic cardiac myocyte dysfunction as a result of impaired calcium handling in isolated cardiac myocytes. Jpn Circ J. 1998; 62 ( 7 ): 505 - 511.
    • (1998) Jpn Circ J , vol.62 , Issue.7 , pp. 505-511
    • Maeda, A.1    Honda, M.2    Kuramochi, T.3    Takabatake, T.4
  • 34
    • 34548324275 scopus 로고    scopus 로고
    • Anthracycline-induced phospholipase A2 inhibition
    • Swift L, McHowat J, Sarvazyan N. Anthracycline-induced phospholipase A2 inhibition. Cardiovasc Toxicol. 2007; 7 ( 2 ): 86 - 91.
    • (2007) Cardiovasc Toxicol. , vol.7 , Issue.2 , pp. 86-91
    • Swift, L.1    McHowat, J.2    Sarvazyan, N.3
  • 37
    • 84872558572 scopus 로고    scopus 로고
    • The dual-targeted HER1/HER2 tyrosine kinase inhibitor lapatinib strongly potentiates the cardiac myocyte-damaging effects of doxorubicin
    • Hasinoff BB, Patel D, Wu X. The dual-targeted HER1/HER2 tyrosine kinase inhibitor lapatinib strongly potentiates the cardiac myocyte-damaging effects of doxorubicin. Cardiovasc Toxicol. 2013; 13 ( 1 ): 33 - 47.
    • (2013) Cardiovasc Toxicol. , vol.13 , Issue.1 , pp. 33-47
    • Hasinoff, B.B.1    Patel, D.2    Wu, X.3
  • 38
    • 0023092732 scopus 로고
    • Dynamic state of collagen: Pathways of collagen degradation in vivo and their possible role in regulation of collagen mass
    • Laurent GJ. Dynamic state of collagen: Pathways of collagen degradation in vivo and their possible role in regulation of collagen mass. Am J Physiol. 1987; 252 ( 1 Pt 1 ): C1 - C9.
    • (1987) Am J Physiol. , vol.252 , Issue.1 , pp. C1-C9
    • Laurent, G.J.1
  • 39
    • 0024319420 scopus 로고
    • Cardiac interstitium in health and disease: The fibrillar collagen network
    • Weber KT. Cardiac interstitium in health and disease: The fibrillar collagen network. J Am Coll Cardiol. 1989; 13 ( 7 ): 1637 - 1652.
    • (1989) J Am Coll Cardiol , vol.13 , Issue.7 , pp. 1637-1652
    • Weber, K.T.1
  • 40
    • 84871796377 scopus 로고    scopus 로고
    • Myofi broblast-mediated mechanisms of pathological remodelling of the heart
    • Weber KT, Sun Y, Bhattacharya SK, Ahokas RA, Gerling IC. Myofi broblast-mediated mechanisms of pathological remodelling of the heart. Nat Rev Cardiol. 2013; 10 ( 1 ): 15 - 26.
    • (2013) Nat Rev Cardiol , vol.10 , Issue.1 , pp. 15-26
    • Weber, K.T.1    Sun, Y.2    Bhattacharya, S.K.3    Ahokas, R.A.4    Gerling, I.C.5
  • 41
    • 0023739984 scopus 로고
    • Coiled perimysial fi bers of papillary muscle in rat heart: Morphology, distribution, and changes in configuration
    • Robinson TF, Geraci MA, Sonnenblick EH, Factor SM. Coiled perimysial fi bers of papillary muscle in rat heart: Morphology, distribution, and changes in configuration. Circ Res. 1988; 63 ( 3 ): 577 - 592.
    • (1988) Circ Res. , vol.63 , Issue.3 , pp. 577-592
    • Robinson, T.F.1    Geraci, M.A.2    Sonnenblick, E.H.3    Factor, S.M.4
  • 42
    • 0000730512 scopus 로고
    • The mechanics of ventricular contraction; a cinefluorographic study
    • Rushmer RF, Thal N. The mechanics of ventricular contraction; a cinefluorographic study. Circulation. 1951; 4 ( 2 ): 219 - 228.
    • (1951) Circulation , vol.4 , Issue.2 , pp. 219-228
    • Rushmer, R.F.1    Thal, N.2
  • 43
    • 79953145585 scopus 로고    scopus 로고
    • Thrombopoietin protects against doxorubicin-induced cardiomyopathy, improves cardiac function, and reversely alters specific signalling networks
    • Chan KY, Xiang P, Zhou L, et al. Thrombopoietin protects against doxorubicin-induced cardiomyopathy, improves cardiac function, and reversely alters specific signalling networks. Eur J Heart Fail. 2011; 13 ( 4 ): 366 - 376.
    • (2011) Eur J Heart Fail , vol.13 , Issue.4 , pp. 366-376
    • Chan, K.Y.1    Xiang, P.2    Zhou, L.3
  • 44
    • 33645979697 scopus 로고    scopus 로고
    • Enhanced gene expression of myocardial matrix metalloproteinases 2 and 9 after acute treatment with doxorubicin in mice
    • Kizaki K, Ito R, Okada M, et al. Enhanced gene expression of myocardial matrix metalloproteinases 2 and 9 after acute treatment with doxorubicin in mice. Pharmacol Res. 2006; 53 ( 4 ): 341 - 346.
    • (2006) Pharmacol Res. , vol.53 , Issue.4 , pp. 341-346
    • Kizaki, K.1    Ito, R.2    Okada, M.3
  • 45
    • 31344453935 scopus 로고    scopus 로고
    • Matrix metalloproteinase- 2 and -9 are induced diff erently by doxorubicin in H9C2 cells: Th e role of MAP kinases and NAD(P)H oxidase
    • Spallarossa P, Altieri P, Garibaldi S, et al. Matrix metalloproteinase- 2 and -9 are induced diff erently by doxorubicin in H9c2 cells: Th e role of MAP kinases and NAD(P)H oxidase. Cardiovasc Res. 2006; 69 ( 3 ): 736 - 745.
    • (2006) Cardiovasc Res. , vol.69 , Issue.3 , pp. 736-745
    • Spallarossa, P.1    Altieri, P.2    Garibaldi, S.3
  • 46
    • 0029764601 scopus 로고    scopus 로고
    • S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide
    • Nikitovic D, Holmgren A. S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide. J Biol Chem. 1996; 271 ( 32 ): 19180 - 19185.
    • (1996) J Biol Chem. , vol.271 , Issue.32 , pp. 19180-19185
    • Nikitovic, D.1    Holmgren, A.2
  • 47
    • 0036816939 scopus 로고    scopus 로고
    • Plasma levels of nitrites/nitrates in patients with chronic atrial fi brillation are increased after electrical restoration of sinus rhythm
    • Nikitovic D, Zacharis EA, Manios EG, et al. Plasma levels of nitrites/nitrates in patients with chronic atrial fi brillation are increased after electrical restoration of sinus rhythm. J Interv Card Electrophysiol. 2002; 7 ( 2 ): 171 - 176.
    • (2002) J Interv Card Electrophysiol. , vol.7 , Issue.2 , pp. 171-176
    • Nikitovic, D.1    Zacharis, E.A.2    Manios, E.G.3
  • 48
    • 66149110905 scopus 로고    scopus 로고
    • Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro
    • Mukhopadhyay P, Rajesh M, Batkai S, et al. Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro. Am J Physiol Heart Circ Physiol. 2009; 296 ( 5 ): H1466 - H1483.
    • (2009) Am J Physiol Heart Circ Physiol. , vol.296 , Issue.5 , pp. H1466-H1483
    • Mukhopadhyay, P.1    Rajesh, M.2    Batkai, S.3
  • 49
    • 70349237288 scopus 로고    scopus 로고
    • Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig
    • Goetzenich A, Hatam N, Zernecke A, et al. Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig. J Heart Lung Transplant. 2009; 28 ( 10 ): 1087 - 1093.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.10 , pp. 1087-1093
    • Goetzenich, A.1    Hatam, N.2    Zernecke, A.3
  • 51
    • 84875994759 scopus 로고    scopus 로고
    • Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment
    • Shi J, Wu X, Surma M, et al. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death Dis. 2013;4:e483.
    • (2013) Cell Death Dis. , vol.4 , pp. e483
    • Shi, J.1    Wu, X.2    Surma, M.3
  • 52
    • 84875833199 scopus 로고    scopus 로고
    • Redox-proteomic analysis of doxorubicin-induced altered thiol activity in cardiomyocytes
    • Lin ST, Chou HC, Chen YW, Chan HL. Redox-proteomic analysis of doxorubicin-induced altered thiol activity in cardiomyocytes. Mol Biosyst. 2013; 9 ( 3 ): 447 - 456.
    • (2013) Mol Biosyst. , vol.9 , Issue.3 , pp. 447-456
    • Lin, S.T.1    Chou, H.C.2    Chen, Y.W.3    Chan, H.L.4
  • 53
    • 70349730231 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase regulates cardiac function and fibrosis
    • Kliment CR, Suliman HB, Tobolewski JM, et al. Extracellular superoxide dismutase regulates cardiac function and fibrosis. J Mol Cell Cardiol. 2009; 47 ( 5 ): 730 - 742.
    • (2009) J Mol Cell Cardiol. , vol.47 , Issue.5 , pp. 730-742
    • Kliment, C.R.1    Suliman, H.B.2    Tobolewski, J.M.3
  • 55
    • 0032142834 scopus 로고    scopus 로고
    • Angiotensin II, transforming growth factor- b 1 and repair in the infarcted heart
    • Sun Y, Zhang JQ, Zhang J, Ramires FJA. Angiotensin II, transforming growth factor- b 1 and repair in the infarcted heart. J Mol Cell Cardiol. 1998; 30 ( 8 ): 1559 - 1569.
    • (1998) J Mol Cell Cardiol. , vol.30 , Issue.8 , pp. 1559-1569
    • Sun, Y.1    Zhang, J.Q.2    Zhang, J.3    Ramires, F.J.A.4
  • 56
    • 84866900231 scopus 로고    scopus 로고
    • Matrix control of transforming growth factor-b function
    • Horiguchi M, Ota M, Rifkin DB. Matrix control of transforming growth factor-b function. J Biochem. 2012; 152 ( 4 ): 321 - 329.
    • (2012) J Biochem. , vol.152 , Issue.4 , pp. 321-329
    • Horiguchi, M.1    Ota, M.2    Rifkin, D.B.3
  • 57
    • 79953704166 scopus 로고    scopus 로고
    • Proteomic insights into chronic anthracycline cardiotoxicity
    • Sterba M, Popelova O, Lenco J, et al. Proteomic insights into chronic anthracycline cardiotoxicity. J Mol Cell Cardiol. 2011; 50 ( 5 ): 849 - 862.
    • (2011) J Mol Cell Cardiol , vol.50 , Issue.5 , pp. 849-862
    • Sterba, M.1    Popelova, O.2    Lenco, J.3
  • 58
    • 84863268717 scopus 로고    scopus 로고
    • Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis
    • Sopel M, Falkenham A, Oxner A, Ma I, Lee TD, Legare JF. Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis. Int J Exp Pathol. 2012; 93 ( 2 ): 115 - 124.
    • (2012) Int J Exp Pathol. , vol.93 , Issue.2 , pp. 115-124
    • Sopel, M.1    Falkenham, A.2    Oxner, A.3    Ma, I.4    Lee, T.D.5    Legare, J.F.6
  • 59
    • 84859652373 scopus 로고    scopus 로고
    • Regional mechanics determine collagen fiber structure in healing myocardial infarcts
    • Fomovsky GM, Rouillard AD, Holmes JW. Regional mechanics determine collagen fiber structure in healing myocardial infarcts. J Mol Cell Cardiol. 2012; 52 ( 5 ): 1083 - 1090.
    • (2012) J Mol Cell Cardiol , vol.52 , Issue.5 , pp. 1083-1090
    • Fomovsky, G.M.1    Rouillard, A.D.2    Holmes, J.W.3
  • 60
    • 84859585326 scopus 로고    scopus 로고
    • Chronic cardiotoxicity of doxorubicin involves activation of myocardial and circulating matrix metalloproteinases in rats
    • Ivanova M, Dovinova I, Okruhlicova L, et al. Chronic cardiotoxicity of doxorubicin involves activation of myocardial and circulating matrix metalloproteinases in rats. Acta Pharmacol Sin. 2012; 33 ( 4 ): 459 - 469.
    • (2012) Acta Pharmacol Sin. , vol.33 , Issue.4 , pp. 459-469
    • Ivanova, M.1    Dovinova, I.2    Okruhlicova, L.3
  • 61
    • 34447120773 scopus 로고    scopus 로고
    • Effects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in doxorubicin cardiomyopathy in a rabbit model
    • Aupperle H, Garbade J, Schubert A, et al. Eff ects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in doxorubicin cardiomyopathy in a rabbit model. Vet Pathol. 2007; 44 ( 4 ): 494 - 503.
    • (2007) Vet Pathol , vol.44 , Issue.4 , pp. 494-503
    • Aupperle, H.1    Garbade, J.2    Schubert, A.3
  • 62
    • 77957191657 scopus 로고    scopus 로고
    • Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits
    • Adamcova M, Potacova A, Popelova O, et al. Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits. Physiol Res. 2010; 59 ( 5 ): 831 - 836.
    • (2010) Physiol Res. , vol.59 , Issue.5 , pp. 831-836
    • Adamcova, M.1    Potacova, A.2    Popelova, O.3
  • 63
    • 79960905670 scopus 로고    scopus 로고
    • Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy
    • van Almen GC, Swinnen M, Carai P, et al. Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. J Mol Cell Cardiol. 2011; 51 ( 3 ): 318 - 328.
    • (2011) J Mol Cell Cardiol , vol.51 , Issue.3 , pp. 318-328
    • Van Almen, G.C.1    Swinnen, M.2    Carai, P.3
  • 64
    • 77955907280 scopus 로고    scopus 로고
    • Cystatin c increases in cardiac injury: A role in extracellular matrix protein modulation
    • Xie L, Terrand J, Xu B, Tsaprailis G, Boyer J, Chen QM. Cystatin C increases in cardiac injury: A role in extracellular matrix protein modulation. Cardiovasc Res. 2010; 87 ( 4 ): 628 - 635.
    • (2010) Cardiovasc Res. , vol.87 , Issue.4 , pp. 628-635
    • Xie, L.1    Terrand, J.2    Xu, B.3    Tsaprailis, G.4    Boyer, J.5    Chen, Q.M.6
  • 65
    • 78549271520 scopus 로고    scopus 로고
    • Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with doxorubicin chemotherapy
    • Zhao Y, McLaughlin D, Robinson E, et al. Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy. Cancer Res. 2010; 70 ( 22 ): 9287 - 9297.
    • (2010) Cancer Res. , vol.70 , Issue.22 , pp. 9287-9297
    • Zhao, Y.1    McLaughlin, D.2    Robinson, E.3
  • 66
    • 84867608210 scopus 로고    scopus 로고
    • Chronic anthracycline cardiotoxicity: Molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways
    • Jirkovsky E, Popelova O, Krivakova-Stankova P, et al. Chronic anthracycline cardiotoxicity: Molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways. J Pharmacol Exp Th er. 2012; 343 ( 2 ): 468 - 478.
    • (2012) J Pharmacol Exp Th Er. , vol.343 , Issue.2 , pp. 468-478
    • Jirkovsky, E.1    Popelova, O.2    Krivakova-Stankova, P.3
  • 67
    • 73949090093 scopus 로고    scopus 로고
    • Cyclophosphamide, epirubicin, and fluorouracil versus dose-dense epirubicin and cyclophosphamide followed by paclitaxel versus doxorubicin and cyclophosphamide followed by paclitaxel in node-positive or highrisk node-negative breast cancer
    • Burnell M, Levine MN, Chapman JA, et al. Cyclophosphamide, epirubicin, and Fluorouracil versus dose-dense epirubicin and cyclophosphamide followed by Paclitaxel versus Doxorubicin and cyclophosphamide followed by Paclitaxel in node-positive or highrisk node-negative breast cancer. J Clin Oncol. 2010; 28 ( 1 ): 77 - 82.
    • (2010) J Clin Oncol. , vol.28 , Issue.1 , pp. 77-82
    • Burnell, M.1    Levine, M.N.2    Chapman, J.A.3
  • 68
    • 84868712269 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer
    • Lin J, Yu Y, Shigdar S, et al. Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer. PLoS ONE. 2012; 7 ( 11 ): e49277.
    • (2012) PLoS ONE , vol.7 , Issue.11 , pp. e49277
    • Lin, J.1    Yu, Y.2    Shigdar, S.3
  • 69
    • 33845467937 scopus 로고    scopus 로고
    • Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27
    • Venkatakrishnan CD, Tewari AK, Moldovan L, et al. Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27. Am J Physiol Heart Circ Physiol. 2006; 291 ( 6 ): H2680 - H2691.
    • (2006) Am J Physiol Heart Circ Physiol. , vol.291 , Issue.6 , pp. H2680-H2691
    • Venkatakrishnan, C.D.1    Tewari, A.K.2    Moldovan, L.3
  • 70
    • 78149394964 scopus 로고    scopus 로고
    • Effect of telmisartan in limiting the cardiotoxic effect of daunorubicin in rats
    • Arozal W, Watanabe K, Veeraveedu PT, et al. Effect of telmisartan in limiting the cardiotoxic effect of daunorubicin in rats. J Pharm Pharmacol. 2010; 62 ( 12 ): 1776 - 1783.
    • (2010) J Pharm Pharmacol , vol.62 , Issue.12 , pp. 1776-1783
    • Arozal, W.1    Watanabe, K.2    Veeraveedu, P.T.3
  • 71
    • 84856918850 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats
    • Gu R, Bai J, Ling L, et al. Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats. PLoS ONE. 2012; 7 ( 2 ): e31279.
    • (2012) PLoS ONE , vol.7 , Issue.2 , pp. e31279
    • Gu, R.1    Bai, J.2    Ling, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.