Time-Dependent and Tissue-Specific Accumulation of mtDNA and Respiratory Chain Defects in Chronic Doxorubicin Cardiomyopathy

Circulation

Volumn 108, Issue 19, 2003, Pages 2423-2429

  Lebrecht, Dirk ^a   Setzer, Bernhard ^a   Ketelsen, Uwe Peter ^a   Haberstroh, Jörg ^a   Walker, Ulrich A ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cardiomyopathy; Drugs; Genetics; Metabolism; Pathology

Indexed keywords

CITRATE SYNTHASE; CYCLOOXYGENASE 1; CYTOCHROME C OXIDASE; DOXORUBICIN; MITOCHONDRIAL DNA; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ENZYME ACTIVITY; EUTHANASIA; HEART MUSCLE; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SKELETAL MUSCLE; TIME; TISSUE SPECIFICITY;

AGE FACTORS; ANIMALS; CARDIOMYOPATHIES; DNA DAMAGE; DNA, MITOCHONDRIAL; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX IV; MALE; MITOCHONDRIA; MUSCLE, SKELETAL; MYOCARDIUM; ORGAN SPECIFICITY; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TIME FACTORS;

EID: 0242442100     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000093196.59829.DF     Document Type: Article

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