Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria

Anticancer Research

Volumn 23, Issue 3 B, 2003, Pages 2445-2450

  Clementi, Maria Elisabetta ^a   Giardina, Bruno ^a   Di Stasio, Enrico ^a   Mordente, Alvaro ^a   Misiti, Francesco ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Adriamycin aglycones; Cytochrome c; Doxorubicin; Doxorubicinol; Mitochondria

Indexed keywords

ADRIAMYCINONE; ANTINEOPLASTIC AGENT; CASPASE; CYTOCHROME C; DOXORUBICIN; DOXORUBICIN DERIVATIVE; DOXORUBICINOL; DOXORUBICINOL AGLYCONE; DRUG METABOLITE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CARDIOTOXICITY; DRUG METABOLISM; ENZYME RELEASE; HEART MITOCHONDRION; HEART MUSCLE OXYGEN CONSUMPTION; MEMBRANE POTENTIAL; METABOLITE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ALDOSTERONE SYNTHASE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOTTING, WESTERN; DOXORUBICIN; FLUOROMETRY; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA, HEART; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0041304980     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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