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Volumn 117, Issue 1, 2007, Pages 6-15

Adriamycin-induced myocardial toxicity: New solutions for an old problem?

Author keywords

Adriamycin; Cardiomyopathy; Myocardial toxicity

Indexed keywords

ALPHA TOCOPHEROL; ANTHRACYCLINE DERIVATIVE; ANTIOXIDANT; BUTYLATED HYDROXYANISOLE; CAPTOPRIL; CENTELLA ASIATICA EXTRACT; CYCLOPHOSPHAMIDE; DOXORUBICIN; ENALAPRIL; EPIRUBICIN; FREE RADICAL; IRON; LIPOSOME; MACROGOL; MELATONIN; MITOXANTRONE; PLACEBO; PREDNISOLONE; RAZOXANE; RETINOL; SODIUM TANSHINONE 2A; TEMOCAPRIL; UNCLASSIFIED DRUG; VALSARTAN; VINCRISTINE;

EID: 33947128057     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2006.05.005     Document Type: Review
Times cited : (124)

References (99)
  • 2
    • 0014473575 scopus 로고
    • Adriamycin (NSC-123127): a new antibiotic with antitumor activity
    • Di Marco A., Gaetani M., and Scarpinato B. Adriamycin (NSC-123127): a new antibiotic with antitumor activity. Cancer Chemother Rep 53 (1969) 33-37
    • (1969) Cancer Chemother Rep , vol.53 , pp. 33-37
    • Di Marco, A.1    Gaetani, M.2    Scarpinato, B.3
  • 3
    • 10044264624 scopus 로고    scopus 로고
    • Anthracycline-induced cardiotoxicity
    • Petit T. Anthracycline-induced cardiotoxicity. Bull Cancer 91 (2004) 159-165
    • (2004) Bull Cancer , vol.91 , pp. 159-165
    • Petit, T.1
  • 4
    • 0141786833 scopus 로고    scopus 로고
    • Cardiac safety of liposomal anthracyclines
    • Safra T. Cardiac safety of liposomal anthracyclines. Oncologist 8 (2003) 17-24
    • (2003) Oncologist , vol.8 , pp. 17-24
    • Safra, T.1
  • 5
    • 0043237846 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiac mitochondrionopathy
    • Wallace K.B. Doxorubicin-induced cardiac mitochondrionopathy. Pharmacol Toxicol 93 (2003) 105-115
    • (2003) Pharmacol Toxicol , vol.93 , pp. 105-115
    • Wallace, K.B.1
  • 6
    • 0018716636 scopus 로고
    • Risk factors for doxorubicin-induced congestive heart failure
    • Von Hoff D.D., Layard M.W., and Basa P. Risk factors for doxorubicin-induced congestive heart failure. Ann Intern Med 91 (1979) 710-717
    • (1979) Ann Intern Med , vol.91 , pp. 710-717
    • Von Hoff, D.D.1    Layard, M.W.2    Basa, P.3
  • 7
    • 0017335116 scopus 로고
    • Adriamycin cardiotoxicity in children: case reports
    • Prout N.M., Richards M.J.S., and Chung J.K. Adriamycin cardiotoxicity in children: case reports. Cancer 39 (1977) 62-65
    • (1977) Cancer , vol.39 , pp. 62-65
    • Prout, N.M.1    Richards, M.J.S.2    Chung, J.K.3
  • 8
    • 0016892443 scopus 로고
    • Acute lethal carditis caused by high-dose combination chemotherapy. A unique clinical and pathological entity
    • Appelbaum F.R., Strauchen J.A., Uraw Jr. R.U., et al. Acute lethal carditis caused by high-dose combination chemotherapy. A unique clinical and pathological entity. Lancet 1 (1976) 58
    • (1976) Lancet , vol.1 , pp. 58
    • Appelbaum, F.R.1    Strauchen, J.A.2    Uraw Jr., R.U.3
  • 9
    • 0017755691 scopus 로고
    • Adriamycin cardiomyopathy: risk factors
    • Minow R.A., Benjamin R.S., and Lee E.I. Adriamycin cardiomyopathy: risk factors. Cancer 39 (1977) 1397-1402
    • (1977) Cancer , vol.39 , pp. 1397-1402
    • Minow, R.A.1    Benjamin, R.S.2    Lee, E.I.3
  • 10
    • 22544447641 scopus 로고    scopus 로고
    • Left ventricular assist device as destination therapy in doxorubicin-induced cardiomyophaty
    • Simsis S.A., Lin S.S., Blue L.J., Gockerman J.P., Russell S.D., and Milano C.A. Left ventricular assist device as destination therapy in doxorubicin-induced cardiomyophaty. Ann Thorac Surg 80 (2005) 717-719
    • (2005) Ann Thorac Surg , vol.80 , pp. 717-719
    • Simsis, S.A.1    Lin, S.S.2    Blue, L.J.3    Gockerman, J.P.4    Russell, S.D.5    Milano, C.A.6
  • 11
    • 0017253191 scopus 로고
    • Adriamycin: energy metabolism and mitochondrial oxidations in the heart of treated rabbits
    • Ferrero M.E., Ferrero E., and Gaja U. Adriamycin: energy metabolism and mitochondrial oxidations in the heart of treated rabbits. Biochem Pharmacol 25 (1976) 125-130
    • (1976) Biochem Pharmacol , vol.25 , pp. 125-130
    • Ferrero, M.E.1    Ferrero, E.2    Gaja, U.3
  • 13
    • 0016718750 scopus 로고
    • Adriamycin (NSC-123 127): mode and mechanism of action
    • Di Marco A. Adriamycin (NSC-123 127): mode and mechanism of action. Cancer Chemother Rep 6 (1975) 91-106
    • (1975) Cancer Chemother Rep , vol.6 , pp. 91-106
    • Di Marco, A.1
  • 14
    • 0017073572 scopus 로고
    • Prevention by coenzyme Q10 of the inhibition of adriamycin of coenzyme Q10 enzymes
    • Kishi T., and Folkers K. Prevention by coenzyme Q10 of the inhibition of adriamycin of coenzyme Q10 enzymes. Cancer Treat Rep 60 (1976) 223-228
    • (1976) Cancer Treat Rep , vol.60 , pp. 223-228
    • Kishi, T.1    Folkers, K.2
  • 15
    • 0017108045 scopus 로고
    • Cardiotoxicity of adriamycin and related anthracyclines
    • Lenaz L., and Page J.A. Cardiotoxicity of adriamycin and related anthracyclines. Cancer Treat Rev 3 (1976) 111-120
    • (1976) Cancer Treat Rev , vol.3 , pp. 111-120
    • Lenaz, L.1    Page, J.A.2
  • 16
    • 2342478428 scopus 로고    scopus 로고
    • Cytokines are not upregulated in adriamycin-induced cardiomyopathy and heart failure
    • Lou H., Danelisen I., and Singal P.K. Cytokines are not upregulated in adriamycin-induced cardiomyopathy and heart failure. J Mol Cell Cardiol 36 (2004) 683-690
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 683-690
    • Lou, H.1    Danelisen, I.2    Singal, P.K.3
  • 17
    • 0028295452 scopus 로고
    • Effects of adriamycin on ionic currents in single cardiac myocytes of the rabbit
    • Earm Y.E., Ho W.K., and So I. Effects of adriamycin on ionic currents in single cardiac myocytes of the rabbit. J Mol Cell Cardiol 26 (1994) 163-172
    • (1994) J Mol Cell Cardiol , vol.26 , pp. 163-172
    • Earm, Y.E.1    Ho, W.K.2    So, I.3
  • 18
    • 0032538809 scopus 로고    scopus 로고
    • In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506
    • Al-Nasser I.A. In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506. Toxicology 131 (1998) 175-181
    • (1998) Toxicology , vol.131 , pp. 175-181
    • Al-Nasser, I.A.1
  • 19
    • 0030899485 scopus 로고    scopus 로고
    • Abnormal beta-adrenergic transmembrane signaling in rabbits with adriamycin-induced cardiomyopathy
    • Nagami K., Yoshikawa T., Suzuki M., Wainai Y., Anzai T., and Handa S. Abnormal beta-adrenergic transmembrane signaling in rabbits with adriamycin-induced cardiomyopathy. Jpn Circ J 61 (1997) 249-255
    • (1997) Jpn Circ J , vol.61 , pp. 249-255
    • Nagami, K.1    Yoshikawa, T.2    Suzuki, M.3    Wainai, Y.4    Anzai, T.5    Handa, S.6
  • 20
    • 0022626649 scopus 로고
    • Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E
    • Milei J., Boveris A., Llesuy S., et al. Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E. Am Heart J 111 (1986) 95-102
    • (1986) Am Heart J , vol.111 , pp. 95-102
    • Milei, J.1    Boveris, A.2    Llesuy, S.3
  • 21
    • 33947173459 scopus 로고
    • Reduction in the toxicity of doxorubicin (adriamycin) in the heart by vitamin E
    • Packer L., and Fuchs J. (Eds), Marcel Dekker Inc, New York Chap 31
    • Milei J., and Llesuy S. Reduction in the toxicity of doxorubicin (adriamycin) in the heart by vitamin E. In: Packer L., and Fuchs J. (Eds). Vitamin E in health and disease (1993), Marcel Dekker Inc, New York 417-431 Chap 31
    • (1993) Vitamin E in health and disease , pp. 417-431
    • Milei, J.1    Llesuy, S.2
  • 22
    • 4544241331 scopus 로고    scopus 로고
    • Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury
    • Chaiswing L., Cole M.P., St Clair D.K., Ittarat W., Szweda L.I., and Oberley T.D. Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury. Toxicol Pathol 32 (2004) 536-547
    • (2004) Toxicol Pathol , vol.32 , pp. 536-547
    • Chaiswing, L.1    Cole, M.P.2    St Clair, D.K.3    Ittarat, W.4    Szweda, L.I.5    Oberley, T.D.6
  • 23
    • 5144227343 scopus 로고    scopus 로고
    • Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity
    • Oliveira P.J., Bjork J.A., Santos M.S., et al. Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity. Toxicol Appl Pharmacol 200 (2004) 159-168
    • (2004) Toxicol Appl Pharmacol , vol.200 , pp. 159-168
    • Oliveira, P.J.1    Bjork, J.A.2    Santos, M.S.3
  • 24
    • 0033091198 scopus 로고    scopus 로고
    • Structural and functional impairment of mitochondria in adriamycin-induced cardiomyopathy in mice: suppression of cytochrome c oxidase II gene expression
    • Papadopoulou L.C., Theophilidis G., Thomopoulos G.N., and Tsiftsoglou A.S. Structural and functional impairment of mitochondria in adriamycin-induced cardiomyopathy in mice: suppression of cytochrome c oxidase II gene expression. Biochem Pharmacol 57 (1999) 481-489
    • (1999) Biochem Pharmacol , vol.57 , pp. 481-489
    • Papadopoulou, L.C.1    Theophilidis, G.2    Thomopoulos, G.N.3    Tsiftsoglou, A.S.4
  • 25
    • 0033080175 scopus 로고    scopus 로고
    • Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice
    • Yen H.C., Oberley T.D., Gairola C.G., Szweda L.I., and St Clair D.K. Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice. Arch Biochem Biophys 362 (1999) 59-66
    • (1999) Arch Biochem Biophys , vol.362 , pp. 59-66
    • Yen, H.C.1    Oberley, T.D.2    Gairola, C.G.3    Szweda, L.I.4    St Clair, D.K.5
  • 26
    • 0028593485 scopus 로고
    • Antioxidative activity of benzylideneascorbate and its effect on adriamycin-induced cardiotoxicity
    • Kojima S., Iizuka H., Yamaguchi H., Tanuma S., Kochi M., and Ueno Y. Antioxidative activity of benzylideneascorbate and its effect on adriamycin-induced cardiotoxicity. AntiCancer Res 14 (1994) 1875-1880
    • (1994) AntiCancer Res , vol.14 , pp. 1875-1880
    • Kojima, S.1    Iizuka, H.2    Yamaguchi, H.3    Tanuma, S.4    Kochi, M.5    Ueno, Y.6
  • 27
    • 0028909048 scopus 로고
    • Adriamycin-induced hepatic and myocardial lipid peroxidation and DNA damage, and enhanced excretion of urinary lipid metabolites in rats
    • Bagchi D., Bagchi M., Hassoun E.A., Kelly J., and Stohs S.J. Adriamycin-induced hepatic and myocardial lipid peroxidation and DNA damage, and enhanced excretion of urinary lipid metabolites in rats. Toxicology 95 1-3 (1995) 1-9
    • (1995) Toxicology , vol.95 , Issue.1-3 , pp. 1-9
    • Bagchi, D.1    Bagchi, M.2    Hassoun, E.A.3    Kelly, J.4    Stohs, S.J.5
  • 28
    • 16244364647 scopus 로고    scopus 로고
    • Free radicals mediate cardiac toxicity induced by adriamycin
    • Muraoka S., and Miura T. Free radicals mediate cardiac toxicity induced by adriamycin. Yakugaku Zasshi 123 (2003) 855-866
    • (2003) Yakugaku Zasshi , vol.123 , pp. 855-866
    • Muraoka, S.1    Miura, T.2
  • 29
    • 0017746691 scopus 로고
    • Electron spin rcsonance study on the mode of generation of free radicals of daunomycin, adriamycin and carboquone in NAD(P) H-microsome system
    • Sato 5, Iwaizmi M., Hauda K., and Tamura J. Electron spin rcsonance study on the mode of generation of free radicals of daunomycin, adriamycin and carboquone in NAD(P) H-microsome system. Gann 68 (1977) 603-608
    • (1977) Gann , vol.68 , pp. 603-608
    • Sato 51    Iwaizmi, M.2    Hauda, K.3    Tamura, J.4
  • 30
    • 0021874569 scopus 로고
    • Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 4′epiadriarnycin in mice
    • Llesuy 5, Milei J., Molina H., Boveris A., and Milei S. Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 4′epiadriarnycin in mice. Tumori 71 (1985) 241-249
    • (1985) Tumori , vol.71 , pp. 241-249
    • Llesuy 51    Milei, J.2    Molina, H.3    Boveris, A.4    Milei, S.5
  • 32
    • 13844264114 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure
    • Szenczi O., Kemecsei P., Holthuijsen M.F., et al. Poly (ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure. Biochem Pharmacol 69 (2005) 725-732
    • (2005) Biochem Pharmacol , vol.69 , pp. 725-732
    • Szenczi, O.1    Kemecsei, P.2    Holthuijsen, M.F.3
  • 33
    • 21644455865 scopus 로고    scopus 로고
    • Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply
    • Tokarska-Schlattner M., Zaugg M., da Silva R., et al. Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply. Am J Physiol Heart Circ Physiol 289 (2005) 37-47
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. 37-47
    • Tokarska-Schlattner, M.1    Zaugg, M.2    da Silva, R.3
  • 35
    • 0018351656 scopus 로고
    • Adriamycin and the heart
    • Henderson I.C., and Frei E. Adriamycin and the heart. N Engl J Med 300 (1979) 310-311
    • (1979) N Engl J Med , vol.300 , pp. 310-311
    • Henderson, I.C.1    Frei, E.2
  • 36
    • 0018189958 scopus 로고
    • Overview of cardiac pathology in relation to anthracycline cardiotoxicity
    • Ferrans V. Overview of cardiac pathology in relation to anthracycline cardiotoxicity. Cancer Treat Rep 62 (1978) 955-961
    • (1978) Cancer Treat Rep , vol.62 , pp. 955-961
    • Ferrans, V.1
  • 37
    • 0017656527 scopus 로고
    • Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response
    • Myers C.E., McGuire W.P., and Liss R.H. Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. Science 197 (1977) 165-166
    • (1977) Science , vol.197 , pp. 165-166
    • Myers, C.E.1    McGuire, W.P.2    Liss, R.H.3
  • 38
    • 0018958414 scopus 로고
    • Adriamycin cardiotoxicity
    • Henderson I.C., and Frei E. Adriamycin cardiotoxicity. Am Heart J 99 (1980) 671
    • (1980) Am Heart J , vol.99 , pp. 671
    • Henderson, I.C.1    Frei, E.2
  • 40
    • 0034255404 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: In vivo study
    • Nakamura T., Ueda Y., Juan Y., Katsuda S., Takahashi H., and Koh E. Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: In vivo study. Circulation 102 (2000) 572-578
    • (2000) Circulation , vol.102 , pp. 572-578
    • Nakamura, T.1    Ueda, Y.2    Juan, Y.3    Katsuda, S.4    Takahashi, H.5    Koh, E.6
  • 41
    • 0036858041 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis in heart dysfunction
    • Kumar D., Lou H., and Singal P.K. Oxidative stress and apoptosis in heart dysfunction. Herz 27 (2002) 662-668
    • (2002) Herz , vol.27 , pp. 662-668
    • Kumar, D.1    Lou, H.2    Singal, P.K.3
  • 42
    • 0019993410 scopus 로고
    • Efficacy and cost of cardiac monitoring in patients receiving doxorubicin
    • Bristow M.R., Lopez M.B., and Mason J.W. Efficacy and cost of cardiac monitoring in patients receiving doxorubicin. Cancer 50 (1982) 32-41
    • (1982) Cancer , vol.50 , pp. 32-41
    • Bristow, M.R.1    Lopez, M.B.2    Mason, J.W.3
  • 43
    • 0019501881 scopus 로고
    • The anthracycline antineoplastic drugs
    • Young R.C., Ozols R.F., and Myers C.E. The anthracycline antineoplastic drugs. N Engl J Med 305 (1981) 139-153
    • (1981) N Engl J Med , vol.305 , pp. 139-153
    • Young, R.C.1    Ozols, R.F.2    Myers, C.E.3
  • 44
    • 0021063443 scopus 로고
    • Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule: assessment by endocardial biopsy
    • Torti F.M., Bristow M.R., and Howes A.E. Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule: assessment by endocardial biopsy. Ann Intern Med 99 (1983) 745-749
    • (1983) Ann Intern Med , vol.99 , pp. 745-749
    • Torti, F.M.1    Bristow, M.R.2    Howes, A.E.3
  • 45
    • 0027395931 scopus 로고
    • Oxidative stress in mouse heart by antitumoral drugs: a comparative study of doxorubicin and mitoxantrone
    • Lores Arnaiz S., and Llesuy S. Oxidative stress in mouse heart by antitumoral drugs: a comparative study of doxorubicin and mitoxantrone. Toxicology 77 (1993) 31-38
    • (1993) Toxicology , vol.77 , pp. 31-38
    • Lores Arnaiz, S.1    Llesuy, S.2
  • 46
    • 0016829549 scopus 로고
    • Some observations on the toxicity of adriamycin (NSC123127)
    • Philips E.S., Gilladoga A., and Marquardt H. Some observations on the toxicity of adriamycin (NSC123127). Cancer Chemother Rep 6 (1975) 177-181
    • (1975) Cancer Chemother Rep , vol.6 , pp. 177-181
    • Philips, E.S.1    Gilladoga, A.2    Marquardt, H.3
  • 47
    • 0020381274 scopus 로고
    • Prenylamine inhibition of adriamycin-induced cardiomyopathy in mice
    • Milei J., Bolomo N.J., and Marantz A. Prenylamine inhibition of adriamycin-induced cardiomyopathy in mice. Medicina (B Aires) 42 (1982) 409-414
    • (1982) Medicina (B Aires) , vol.42 , pp. 409-414
    • Milei, J.1    Bolomo, N.J.2    Marantz, A.3
  • 49
    • 0033997829 scopus 로고    scopus 로고
    • Effect of PSC 833, verapamil and amiodarone on adriamycin toxicity in cultured rat cardiomyocytes
    • Estevez M.D., Wolf A., and Schramm U. Effect of PSC 833, verapamil and amiodarone on adriamycin toxicity in cultured rat cardiomyocytes. Toxicol In Vitro 14 (2000) 17-23
    • (2000) Toxicol In Vitro , vol.14 , pp. 17-23
    • Estevez, M.D.1    Wolf, A.2    Schramm, U.3
  • 50
    • 0033841967 scopus 로고    scopus 로고
    • The protective effect of glutathione administration on adriamycin-induced acute cardiac toxicity in rats
    • Mohamed H.E., El-Sw Estevez efy S.E., and Hagar H.H. The protective effect of glutathione administration on adriamycin-induced acute cardiac toxicity in rats. Pharmacol Res 42 (2000) 115-121
    • (2000) Pharmacol Res , vol.42 , pp. 115-121
    • Mohamed, H.E.1    El-Sw Estevez efy, S.E.2    Hagar, H.H.3
  • 51
    • 0035213759 scopus 로고    scopus 로고
    • Attenuation of the acute adriamycin-induced cardiac and hepatic oxidative toxicity by N-(2-mercaptopropionyl) glycine in rats
    • el-Missiry M.A., Othman A.I., Amer M.A., and Abd el-Aziz M.A. Attenuation of the acute adriamycin-induced cardiac and hepatic oxidative toxicity by N-(2-mercaptopropionyl) glycine in rats. Free Radic Res 35 (2001) 575-581
    • (2001) Free Radic Res , vol.35 , pp. 575-581
    • el-Missiry, M.A.1    Othman, A.I.2    Amer, M.A.3    Abd el-Aziz, M.A.4
  • 52
    • 0038476528 scopus 로고    scopus 로고
    • Protective role of dl-alpha-lipoic acid against adriamycin-induced cardiac lipid peroxidation
    • Balachandar A.V., Malarkodi K.P., and Varalakshmi P. Protective role of dl-alpha-lipoic acid against adriamycin-induced cardiac lipid peroxidation. Hum Exp Toxicol 22 (2003) 249-254
    • (2003) Hum Exp Toxicol , vol.22 , pp. 249-254
    • Balachandar, A.V.1    Malarkodi, K.P.2    Varalakshmi, P.3
  • 53
    • 16644399080 scopus 로고    scopus 로고
    • Effect of soybean isoflavones on heart function of rats with adriamycin-induced heart failure
    • Ma S.F., Guan S.D., and Zhu Y. Effect of soybean isoflavones on heart function of rats with adriamycin-induced heart failure. Zhong Xi Yi Jie He Xue Bao 2 (2004) 278-280
    • (2004) Zhong Xi Yi Jie He Xue Bao , vol.2 , pp. 278-280
    • Ma, S.F.1    Guan, S.D.2    Zhu, Y.3
  • 54
  • 55
    • 0033844470 scopus 로고    scopus 로고
    • Propionyl-l-carnitine as potential protective agent against adriamycin-induced impairment of fatty acid beta-oxidation in isolated heart mitochondria
    • Sayed-Ahmed M.M., Shouman S.A., Rezk B.M., Khalifa M.H., Osman A.M., and El-Merzabani M.M. Propionyl-l-carnitine as potential protective agent against adriamycin-induced impairment of fatty acid beta-oxidation in isolated heart mitochondria. Pharmacol Res 41 (2000) 143-150
    • (2000) Pharmacol Res , vol.41 , pp. 143-150
    • Sayed-Ahmed, M.M.1    Shouman, S.A.2    Rezk, B.M.3    Khalifa, M.H.4    Osman, A.M.5    El-Merzabani, M.M.6
  • 56
    • 0037056109 scopus 로고    scopus 로고
    • Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity
    • Shioji K., Kishimoto C., Nakamura H., et al. Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation 106 (2002) 1403-1409
    • (2002) Circulation , vol.106 , pp. 1403-1409
    • Shioji, K.1    Kishimoto, C.2    Nakamura, H.3
  • 58
    • 0016761202 scopus 로고
    • Synthesis and antitumor properties of new glycosides of daumonycine and adriamycine
    • Arcomone F., Penco S., Vigevani A., et al. Synthesis and antitumor properties of new glycosides of daumonycine and adriamycine. J Med Chem 18 (1975) 703-707
    • (1975) J Med Chem , vol.18 , pp. 703-707
    • Arcomone, F.1    Penco, S.2    Vigevani, A.3
  • 59
    • 0344497544 scopus 로고
    • Antitumor activity, toxicity and pharmacological properties of 4′-epi-adriamycin
    • Siegenthaler A., and Luthy R. (Eds), American Society for Microbiology, Washington, DC
    • Casazza A.M., Di Marco A., and Bertazzoli C. Antitumor activity, toxicity and pharmacological properties of 4′-epi-adriamycin. In: Siegenthaler A., and Luthy R. (Eds). Current chemotherapy (1988), American Society for Microbiology, Washington, DC 1257-1260
    • (1988) Current chemotherapy , pp. 1257-1260
    • Casazza, A.M.1    Di Marco, A.2    Bertazzoli, C.3
  • 60
    • 0007490094 scopus 로고
    • Epirubicin, a therapeutically active doxorubicin analogue with reduced cardiotoxicity
    • Bonadonna U. (Ed), Masson, Milan
    • Young C.W. Epirubicin, a therapeutically active doxorubicin analogue with reduced cardiotoxicity. In: Bonadonna U. (Ed). Advances in anthracycline chemotherapy: epirubicin (1984), Masson, Milan 183-188
    • (1984) Advances in anthracycline chemotherapy: epirubicin , pp. 183-188
    • Young, C.W.1
  • 61
    • 0027207013 scopus 로고
    • In-vivo and in-vitro mitochondrial membrane damages induced in mice by adriamycin and derivatives
    • Praet M., and Ruysschaert J.M. In-vivo and in-vitro mitochondrial membrane damages induced in mice by adriamycin and derivatives. Biochim Biophys Acta 1149 (1993) 79-85
    • (1993) Biochim Biophys Acta , vol.1149 , pp. 79-85
    • Praet, M.1    Ruysschaert, J.M.2
  • 62
    • 0025691471 scopus 로고
    • Hemodynamic effects of chronic 4′epi-adriamycin administration
    • Milei J., Ale J.J., Garay G., et al. Hemodynamic effects of chronic 4′epi-adriamycin administration. Cardiovasc Drugs Ther 4 (1990) 1519-1523
    • (1990) Cardiovasc Drugs Ther , vol.4 , pp. 1519-1523
    • Milei, J.1    Ale, J.J.2    Garay, G.3
  • 63
    • 0025216534 scopus 로고
    • Myocardial damage induced by doxorubicins: hydroperoxide-initiated chemiluminescence and morphology
    • Llesuy S.F., Milei J., Gonzalez Flecha B.S., and Boveris A. Myocardial damage induced by doxorubicins: hydroperoxide-initiated chemiluminescence and morphology. Free Radic Biol Med 8 (1990) 259-264
    • (1990) Free Radic Biol Med , vol.8 , pp. 259-264
    • Llesuy, S.F.1    Milei, J.2    Gonzalez Flecha, B.S.3    Boveris, A.4
  • 64
    • 23044442984 scopus 로고    scopus 로고
    • Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin
    • Kim C., Kim N., Joo H., et al. Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin. J Cardiovasc Pharmacol 46 (2005) 200-210
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 200-210
    • Kim, C.1    Kim, N.2    Joo, H.3
  • 65
    • 0029859768 scopus 로고    scopus 로고
    • Protective effect of butylated hydroxyanisole on adriamycin-induced cardiotoxicity
    • Vora J., Khaw B.A., Narula J., and Boroujerdi M. Protective effect of butylated hydroxyanisole on adriamycin-induced cardiotoxicity. J Pharm Pharmacol 48 (1996) 940-944
    • (1996) J Pharm Pharmacol , vol.48 , pp. 940-944
    • Vora, J.1    Khaw, B.A.2    Narula, J.3    Boroujerdi, M.4
  • 66
    • 0032935672 scopus 로고    scopus 로고
    • Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant
    • Morishima I., Okumura K., Matsui H., et al. Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant. J Pineal Res 26 (1999) 204-210
    • (1999) J Pineal Res , vol.26 , pp. 204-210
    • Morishima, I.1    Okumura, K.2    Matsui, H.3
  • 68
    • 0141786834 scopus 로고    scopus 로고
    • Liposomal anthracyclines: adjuvant and neoadjuvant therapy for breast cancer
    • Campos S. Liposomal anthracyclines: adjuvant and neoadjuvant therapy for breast cancer. Oncologist 8 (2003) 10-16
    • (2003) Oncologist , vol.8 , pp. 10-16
    • Campos, S.1
  • 70
    • 0021029382 scopus 로고
    • Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation
    • Herman E.H., Rahman A., Ferrans V.J., Vick J.A., and Schein P.S. Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res 43 (1983) 5427-5432
    • (1983) Cancer Res , vol.43 , pp. 5427-5432
    • Herman, E.H.1    Rahman, A.2    Ferrans, V.J.3    Vick, J.A.4    Schein, P.S.5
  • 71
    • 0035164058 scopus 로고    scopus 로고
    • A comparison of liposomal formulations of doxorubicin with drug administered in free form: changing toxicity profiles
    • Waterhouse D.N., Tardi P.G., Mayer L.D., and Bally M.B. A comparison of liposomal formulations of doxorubicin with drug administered in free form: changing toxicity profiles. Drug Saf 24 (2001) 903-920
    • (2001) Drug Saf , vol.24 , pp. 903-920
    • Waterhouse, D.N.1    Tardi, P.G.2    Mayer, L.D.3    Bally, M.B.4
  • 72
    • 27144447790 scopus 로고    scopus 로고
    • Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin
    • Veldman R.J., Koning G.A., van Hell A., et al. Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin. J Pharmacol Exp Ther 315 (2005) 704-710
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 704-710
    • Veldman, R.J.1    Koning, G.A.2    van Hell, A.3
  • 74
    • 85026134689 scopus 로고    scopus 로고
    • Coenzyme Q10 and cardiovascular disease: a review
    • Sarter B. Coenzyme Q10 and cardiovascular disease: a review. J Cardiovasc Nurs 16 (2002) 9-20
    • (2002) J Cardiovasc Nurs , vol.16 , pp. 9-20
    • Sarter, B.1
  • 75
    • 0032763156 scopus 로고    scopus 로고
    • Protective effects of sodium tanshinone IIA sulphonate against adriamycin-induced lipid peroxidation in mice hearts in vivo and in vitro
    • Zhou G.Y., Zhao B.L., Hou J.W., Ma G.E., and Xin W.J. Protective effects of sodium tanshinone IIA sulphonate against adriamycin-induced lipid peroxidation in mice hearts in vivo and in vitro. Pharmacol Res 40 6 (Dec 1999) 487-491
    • (1999) Pharmacol Res , vol.40 , Issue.6 , pp. 487-491
    • Zhou, G.Y.1    Zhao, B.L.2    Hou, J.W.3    Ma, G.E.4    Xin, W.J.5
  • 76
    • 8844245648 scopus 로고    scopus 로고
    • Protective effect of centella asiatica on antioxidant tissue defense system against adriamycin induced cardiomyopathy in rats
    • Gnanapragasam A., Ebenezar K.K., Sathish V., Govindaraju P., and Devaki T. Protective effect of centella asiatica on antioxidant tissue defense system against adriamycin induced cardiomyopathy in rats. Life Sci 76 (2004) 585-597
    • (2004) Life Sci , vol.76 , pp. 585-597
    • Gnanapragasam, A.1    Ebenezar, K.K.2    Sathish, V.3    Govindaraju, P.4    Devaki, T.5
  • 77
    • 0028275840 scopus 로고
    • Probucol promotes endogenous antioxidants and provides protection against adriamycin-induced cardiomyopathy in rats
    • Siveski-Iliskovic N., Kaul N., and Singal P.K. Probucol promotes endogenous antioxidants and provides protection against adriamycin-induced cardiomyopathy in rats. Circulation 89 (1994) 2829-2835
    • (1994) Circulation , vol.89 , pp. 2829-2835
    • Siveski-Iliskovic, N.1    Kaul, N.2    Singal, P.K.3
  • 78
    • 0030855953 scopus 로고    scopus 로고
    • Adriamycin cardiomyopathy: pathophysiology and prevention
    • Singal P.K., Iliskovic N., Li T., and Kumar D. Adriamycin cardiomyopathy: pathophysiology and prevention. FASEB J 11 (1997) 931-936
    • (1997) FASEB J , vol.11 , pp. 931-936
    • Singal, P.K.1    Iliskovic, N.2    Li, T.3    Kumar, D.4
  • 79
    • 0017075224 scopus 로고
    • Adriamycin: amelioration of toxicity by tocopherol
    • Myers C.E., McGuire W.P., and Young R. Adriamycin: amelioration of toxicity by tocopherol. Cancer Treat Rep 60 (1976) 961-962
    • (1976) Cancer Treat Rep , vol.60 , pp. 961-962
    • Myers, C.E.1    McGuire, W.P.2    Young, R.3
  • 80
    • 0024261046 scopus 로고
    • Vitamin E deficiency accentuates adriamycin-induced cardiomyopathy and cell surface changes
    • Singal P.K., and Tong J.U. Vitamin E deficiency accentuates adriamycin-induced cardiomyopathy and cell surface changes. Mol Cell Biochem 84 (1988) 163-171
    • (1988) Mol Cell Biochem , vol.84 , pp. 163-171
    • Singal, P.K.1    Tong, J.U.2
  • 81
    • 0018897888 scopus 로고
    • Failure of the antioxidant vitamin E to protect against adriamycin-induced cardiotoxicity in the rabbit
    • Breed J.G.S., Zimmerman A.N.B., Dormans J.A.M.A., and Pinedo H.M. Failure of the antioxidant vitamin E to protect against adriamycin-induced cardiotoxicity in the rabbit. Cancer Res 40 (1980) 2033-2038
    • (1980) Cancer Res , vol.40 , pp. 2033-2038
    • Breed, J.G.S.1    Zimmerman, A.N.B.2    Dormans, J.A.M.A.3    Pinedo, H.M.4
  • 82
    • 0020568774 scopus 로고
    • Influence of vitamin E and ICRF-187 on chronic doxorubicin cardiotoxicity in miniature swine
    • Herman E.H., and Ferrans V.J. Influence of vitamin E and ICRF-187 on chronic doxorubicin cardiotoxicity in miniature swine. Lab Invest 49 (1983) 69-77
    • (1983) Lab Invest , vol.49 , pp. 69-77
    • Herman, E.H.1    Ferrans, V.J.2
  • 83
    • 0018882193 scopus 로고
    • Effect of vitamin E against adriamycin induced toxicity in rabbits
    • Wang Y.M., Madanat F.E., Kimball J.C., et al. Effect of vitamin E against adriamycin induced toxicity in rabbits. Cancer Res 40 (1980) 1022-1026
    • (1980) Cancer Res , vol.40 , pp. 1022-1026
    • Wang, Y.M.1    Madanat, F.E.2    Kimball, J.C.3
  • 84
    • 0020334080 scopus 로고
    • Clinical and pharmacologic investigation of the effects of alfa-tocopherol on adriamycin cardiotoxicity
    • Vitamin E: biochemical, hematological and clinical aspects. Lubin B., and Machlin L. (Eds)
    • Legha S., Wang Y., Mackay B., et al. Clinical and pharmacologic investigation of the effects of alfa-tocopherol on adriamycin cardiotoxicity. In: Lubin B., and Machlin L. (Eds). Vitamin E: biochemical, hematological and clinical aspects. Ann N Y Acad Sci vol. 393 (1982) 411-417
    • (1982) Ann N Y Acad Sci , vol.393 , pp. 411-417
    • Legha, S.1    Wang, Y.2    Mackay, B.3
  • 85
    • 0022399664 scopus 로고
    • Cardiac lesions of selenium-vitamin E deficiency in animals
    • Ferrans V.J., and Van Vleet J.F. Cardiac lesions of selenium-vitamin E deficiency in animals. Heart Vessels 1 (1985) 294-297
    • (1985) Heart Vessels , vol.1 , pp. 294-297
    • Ferrans, V.J.1    Van Vleet, J.F.2
  • 86
    • 0020388922 scopus 로고
    • Myocardial mitochondrial functions in alfa-tocopherol deficient and refed rabbits
    • Chazov E., Smirnov V., and Dhalla N.S. (Eds), Plenum Publishing, New York
    • Guarnieri C., Flamigni E., and Rossoni-Caldarera C. Myocardial mitochondrial functions in alfa-tocopherol deficient and refed rabbits. In: Chazov E., Smirnov V., and Dhalla N.S. (Eds). Advances in myocardiology vol. 3 (1982), Plenum Publishing, New York 621-627
    • (1982) Advances in myocardiology , vol.3 , pp. 621-627
    • Guarnieri, C.1    Flamigni, E.2    Rossoni-Caldarera, C.3
  • 87
    • 0020400199 scopus 로고
    • Effect of oxygen radicals on heart mitochondrial function in alfa-tocopherol deficient rabbits
    • Fiamigni E., Guarnieri C., Toni C., and Caldarera C.M. Effect of oxygen radicals on heart mitochondrial function in alfa-tocopherol deficient rabbits. Int J Vitam Nutr Res 52 (1982) 402-406
    • (1982) Int J Vitam Nutr Res , vol.52 , pp. 402-406
    • Fiamigni, E.1    Guarnieri, C.2    Toni, C.3    Caldarera, C.M.4
  • 88
    • 0018052898 scopus 로고
    • Effect of selenium and vitamin E on adriamycin-induced cardiomyopathy in rabbits
    • Van Vleet J.F., Greenwood L., Ferrans V.J., and Rebar A.H. Effect of selenium and vitamin E on adriamycin-induced cardiomyopathy in rabbits. Ann J Vet Rev 39 (1978) 997-1010
    • (1978) Ann J Vet Rev , vol.39 , pp. 997-1010
    • Van Vleet, J.F.1    Greenwood, L.2    Ferrans, V.J.3    Rebar, A.H.4
  • 89
    • 0016695310 scopus 로고
    • Experimental adriamycin cardiotoxicity prevented by ubiquinone "in vivo" rabbits
    • Bertazzoli C., Sala L., and Solcia E. Experimental adriamycin cardiotoxicity prevented by ubiquinone "in vivo" rabbits. Int Res Commun Syst Med Sci 3 (1975) 468
    • (1975) Int Res Commun Syst Med Sci , vol.3 , pp. 468
    • Bertazzoli, C.1    Sala, L.2    Solcia, E.3
  • 91
    • 0015715739 scopus 로고
    • Drug profile: synadrin (prenylamine)
    • Murphy J.E. Drug profile: synadrin (prenylamine). J Int Med Res 1 (1973) 204-208
    • (1973) J Int Med Res , vol.1 , pp. 204-208
    • Murphy, J.E.1
  • 92
    • 0023855207 scopus 로고
    • The role of prenylamine in the prevention of adriamycin-induced cardiotoxicity. A review of experimental and clinical findings
    • Milei J., Vazquez A., Boveris A., et al. The role of prenylamine in the prevention of adriamycin-induced cardiotoxicity. A review of experimental and clinical findings. J Int Med Res 16 (1988) 19-30
    • (1988) J Int Med Res , vol.16 , pp. 19-30
    • Milei, J.1    Vazquez, A.2    Boveris, A.3
  • 93
    • 0023578882 scopus 로고
    • Prevention of adriamycin-induced cardiotoxicity by prenylamine: a pilot double blind study
    • Milei J., Marantz A., Ale J., Vazquez A., and Buceta J.E. Prevention of adriamycin-induced cardiotoxicity by prenylamine: a pilot double blind study. Cancer Drug Deliv 4 (1987) 129-136
    • (1987) Cancer Drug Deliv , vol.4 , pp. 129-136
    • Milei, J.1    Marantz, A.2    Ale, J.3    Vazquez, A.4    Buceta, J.E.5
  • 94
    • 28044442932 scopus 로고    scopus 로고
    • Notable effects of angiotensin II receptor blocker, valsartan, on acute cardiotoxic changes after standard chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisolone
    • [ahead of print]
    • Nakamae H., Tsumura K., Terada Y., et al. Notable effects of angiotensin II receptor blocker, valsartan, on acute cardiotoxic changes after standard chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisolone. Cancer (Oct 24 2005) [ahead of print]
    • (2005) Cancer
    • Nakamae, H.1    Tsumura, K.2    Terada, Y.3
  • 95
    • 0033840876 scopus 로고    scopus 로고
    • Prevention of doxorubicin (adriamycin)-induced cardiomyopathy by simultaneous administration of angiotensin-converting enzyme inhibitor assessed by acoustic densitometry
    • Tokudome T., Mizushige K., Noma T., et al. Prevention of doxorubicin (adriamycin)-induced cardiomyopathy by simultaneous administration of angiotensin-converting enzyme inhibitor assessed by acoustic densitometry. J Cardiovasc Pharmacol 36 (2000) 361-368
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 361-368
    • Tokudome, T.1    Mizushige, K.2    Noma, T.3
  • 96
    • 16244402976 scopus 로고    scopus 로고
    • Superoxide dismutase activity in adriamycin-induced cardiotoxicity in humans: a potential novel tool for risk stratification
    • Rohde L.E., Bello-Klein A., Pereira R.P., et al. Superoxide dismutase activity in adriamycin-induced cardiotoxicity in humans: a potential novel tool for risk stratification. J Card Fail 11 (2005) 220-226
    • (2005) J Card Fail , vol.11 , pp. 220-226
    • Rohde, L.E.1    Bello-Klein, A.2    Pereira, R.P.3
  • 97
    • 13644261776 scopus 로고    scopus 로고
    • Change and significance of nuclear factor-kappaB in adriamycin induced cardiomyopathy in rats
    • Li H.L., Liu B., Zhou L.W., and Yu W.H. Change and significance of nuclear factor-kappaB in adriamycin induced cardiomyopathy in rats. Chin Med J 118 (2005) 111-115
    • (2005) Chin Med J , vol.118 , pp. 111-115
    • Li, H.L.1    Liu, B.2    Zhou, L.W.3    Yu, W.H.4
  • 98
    • 0036628953 scopus 로고    scopus 로고
    • Correlation of simultaneous differential gene expression in the blood and heart with known mechanisms of adriamycin-induced cardiomyopathy in the rat
    • Brown H.R., Ni H., Benavides G., et al. Correlation of simultaneous differential gene expression in the blood and heart with known mechanisms of adriamycin-induced cardiomyopathy in the rat. Toxicol Pathol 30 (2002) 452-469
    • (2002) Toxicol Pathol , vol.30 , pp. 452-469
    • Brown, H.R.1    Ni, H.2    Benavides, G.3
  • 99
    • 23744457621 scopus 로고    scopus 로고
    • Monitoring cardiac function in patients receiving doxorubicin
    • Lu P. Monitoring cardiac function in patients receiving doxorubicin. Semin Nucl Med 35 (2005) 197-201
    • (2005) Semin Nucl Med , vol.35 , pp. 197-201
    • Lu, P.1


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