Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants

Food and Chemical Toxicology

Volumn 61, Issue , 2013, Pages 240-247

  Juránek, Ivo ^a   Nikitovic, Dragana ^b   Kouretas, Dimitrios ^c   Hayes, A Wallace ^d   Tsatsakis, Aristidis M ^b  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^b UNIVERSITY OF CRETE   (Greece)

^c UNIVERSITY OF THESSALY   (Greece)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Biological importance of reactive oxygen species; Deleterious action; Exogenous antioxidants; Signaling role; Tissue injury

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CALCIUM; FLAVONOID; OXYGEN; PLACEBO; REACTIVE OXYGEN METABOLITE; XANTHINE OXIDASE;

ARTICLE; BIODIVERSITY; CANCER PREVENTION; CARDIOVASCULAR DISEASE; CELL MEMBRANE FLUIDITY; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; CYTOSOL; DEFENSE MECHANISM; EVOLUTION; HEAD AND NECK CANCER; HUMAN; HYPOXIA; LEUKOCYTE ACTIVATION; LIPID PEROXIDATION; LUNG CANCER; MITOCHONDRIAL RESPIRATION; MOLECULARLY TARGETED THERAPY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PHAGOCYTOSIS; RADIATION PROTECTION; REPERFUSION INJURY; SKIN CANCER; TISSUE INJURY;

BIOLOGICAL IMPORTANCE OF REACTIVE OXYGEN SPECIES; DELETERIOUS ACTION; EXOGENOUS ANTIOXIDANTS; SIGNALING ROLE; TISSUE INJURY;

ANIMALS; ANTIOXIDANTS; BIODIVERSITY; BIOLOGICAL EVOLUTION; CLINICAL TRIALS AS TOPIC; CYTOSOL; FREE RADICALS; GENOME; HUMANS; NEOPLASMS; OXIDATIVE STRESS; OXYGEN; REACTIVE OXYGEN SPECIES;

EID: 84888843756     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.08.074     Document Type: Article

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