Interplay between amino acid residues at positions 192 and 115 in modulating hydrolytic activities of human paraoxonase 1

Biochimie

Volumn 105, Issue , 2014, Pages 202-210

  Bajaj, Priyanka ^a   Aggarwal, Geetika ^a   Tripathy, Rajan K ^a   Pande, Abhay H ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Acyl homoserine lactone; LDL oxidation; Organophosphate; Recombinant human PON1

Indexed keywords

AMINO ACID; ARYLDIALKYLPHOSPHATASE 1; ARYLESTERASE; COPPER SULFATE; GLUCONOLACTONASE; HUMAN PARAOXONASE 1; HYDROLASE; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN; N ACYLHOMOSERINE LACTONE; PARAOXON; RECOMBINANT ENZYME; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ARYLDIALKYLPHOSPHATASE; PON1 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL CELL; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYMATIC ASSAY; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; HUMAN; HYDROLYSIS; LIPID PEROXIDATION; NONHUMAN; NORMAL HUMAN; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; SITE DIRECTED MUTAGENESIS; WILD TYPE; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; GENETICS; KINETICS; MOLECULAR GENETICS; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACIDS; ARYLDIALKYLPHOSPHATASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HUMANS; HYDROLYSIS; KINETICS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84907857537     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.07.024     Document Type: Article

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