A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Gabl, Michael ^a   Winther, Malene ^a   Skovbakke, Sarah Line ^a,b   Bylund, Johan ^a,c   Dahlgren, Claes ^a   Forsman, Huamei ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 2; PEPDUCIN; PEPTIDE; PROTEIN INHIBITOR; PURINERGIC P2Y2 RECEPTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG; CALCIUM; FPR2 PROTEIN, HUMAN; LIPOXIN RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR INTERACTION; NEUTROPHIL; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THIRD INTRACELLULAR LOOP; METABOLISM; PHYSIOLOGY;

CALCIUM; HUMANS; NADPH OXIDASE; NEUTROPHILS; RECEPTOR CROSS-TALK; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LIPOXIN; SIGNAL TRANSDUCTION;

EID: 84907828100     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109516     Document Type: Article

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