A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils

Journal of Immunological Methods

Volumn 352, Issue 1-2, 2010, Pages 45-53

  Karlsson, Jennie ^a   Bylund, Johan ^a   Movitz, Charlotta ^a   Björkman, Lena ^a   Forsman, Huamei ^a   Dahlgren, Claes ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Calcium influx; Desensitization; Formyl peptide receptors; Human; NADPH oxidase; Neutrophil

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; FORMYLPEPTIDE RECEPTOR; HYDROGEN PEROXIDE; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CALCIUM CELL LEVEL; CATALYSIS; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; DESENSITIZATION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL;

CALCIUM; CELL LINE, TUMOR; CELL SEPARATION; FLOW CYTOMETRY; GRANULOCYTES; HUMANS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHIL ACTIVATION; PEROXIDASE; RECEPTORS, FORMYL PEPTIDE; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 71749102179     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2009.10.011     Document Type: Article

References (31)

1. 2+ influx across the plasma membrane of human neutrophils. Mol. Pharmacol. 30 (1986) 437
2. Bagorda A., Mihaylov V.A., and Parent C.A. Chemotaxis: moving forward and holding on to the past. Thromb. Haemost. 95 (2006) 12
3. Bellner L., Thoren F., Nygren E., Liljeqvist J.A., Karlsson A., and Eriksson K. A proinflammatory peptide from herpes simplex virus type 2 glycoprotein G affects neutrophil, monocyte, and NK cell functions. J. Immunol. 174 (2005) 2235
4. Berg M., and James S.P. Human neutrophils release the Leu-8 lymph node homing receptor during cell activation. Blood 76 (1990) 2381
5. Bjorkman L., Karlsson J., Karlsson A., Rabiet M.J., Boulay F., Fu H., Bylund J., and Dahlgren C. Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1. J. Leukoc. Biol. 83 (2008) 245
6. Briheim G., Stendahl O., and Dahlgren C. Factor-specific deactivation of leukocyte chemotaxis in vivo. Scand. J. Haematol. 37 (1986) 253
7. Bylund J., Christophe T., Boulay F., Nystrom T., Karlsson A., and Dahlgren C. Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori. Antimicrob. Agents Chemother. 45 (2001) 1700
8. 2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J. Biol. Chem. 276 (2001) 21585
9. Clark R.A. Chemotactic factors trigger their own oxidative inactivation by human neutrophils. J. Immunol. 129 (1982) 2725
10. Dahlgren C., and Karlsson A. Respiratory burst in human neutrophils. J. Immunol. Methods 232 (1999) 3
11. Ferguson S.S. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53 (2001) 1
12. Follin P. Skin chamber technique for study of in vivo exudated human neutrophils. J. Immunol. Methods 232 (1999) 55
13. Follin P., and Dahlgren C. A skin chamber technique as a human model for studies of aseptic inflammatory reactions. Methods Mol. Biol. 412 (2007) 333
14. Forsman H., Salomonsson E., Onnheim K., Karlsson J., Bjorstad A., Leffler H., Bylund J., Karlsson A., and Dahlgren C. The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. Glycobiology 18 (2008) 905
15. Fu H., Bylund J., Karlsson A., Pellme S., and Dahlgren C. The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8. Immunology 112 (2004) 201
16. Heit B., Tavener S., Raharjo E., and Kubes P. An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J. Cell Biol. 159 (2002) 91
17. Hu J.Y., Le Y., Gong W., Dunlop N.M., Gao J.L., Murphy P.M., and Wang J.M. Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1. J. Leukoc. Biol. 70 (2001) 155
18. Huber A.R., Kunkel S.L., Todd III R.F., and Weiss S.J. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 254 (1991) 99
19. Huet E., Boulay F., Barral S., and Rabiet M.J. The role of beta-arrestins in the formyl peptide receptor-like 1 internalization and signaling. Cell. Signal. 19 (2007) 1939
20. Johansson A., and Dahlgren C. Characterization of the luminol-amplified light-generating reaction induced in human monocytes. J. Leukoc. Biol. 45 (1989) 444
21. Karlsson J., Fu H., Boulay F., Dahlgren C., Hellstrand K., and Movitz C. Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors. J. Leukoc. Biol. 78 (2005) 762
22. Klotz K.N., Krotec K.L., Gripentrog J., and Jesaitis A.J. Regulatory interaction of N-formyl peptide chemoattractant receptors with the membrane skeleton in human neutrophils. J. Immunol. 152 (1994) 801
23. Le Y., Gong W., Tiffany H.L., Tumanov A., Nedospasov S., Shen W., Dunlop N.M., Gao J.L., Murphy P.M., Oppenheim J.J., and Wang J.M. Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J. Neurosci. 21 (2001) RC123
24. Le Y., Yazawa H., Gong W., Yu Z., Ferrans V.J., Murphy P.M., and Wang J.M. The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1. J. Immunol. 166 (2001) 1448
25. Lim L.H., and Pervaiz S. Annexin 1: the new face of an old molecule. Faseb J. 21 (2007) 968
26. Lundqvist H., and Dahlgren C. Isoluminol-enhanced chemiluminescence: a sensitive method to study the release of superoxide anion from human neutrophils. Free Radic. Biol. Med. 20 (1996) 785
27. Nauseef W.M., Metcalf J.A., and Root R.K. Role of myeloperoxidase in the respiratory burst of human neutrophils. Blood 61 (1983) 483
28. Novak E.J., and Rabinovitch P.S. Improved sensitivity in flow cytometric intracellular ionized calcium measurement using fluo-3/Fura Red fluorescence ratios. Cytometry 17 (1994) 135
29. Prossnitz E.R. Desensitization of N-formylpeptide receptor-mediated activation is dependent upon receptor phosphorylation. J. Biol. Chem. 272 (1997) 15213
30. Tucker K.A., Lilly M.B., Heck Jr. L., and Rado T.A. Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood 70 (1987) 372
31. Zhen L., King A.A., Xiao Y., Chanock S.J., Orkin S.H., and Dinauer M.C. Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 9832