메뉴 건너뛰기




Volumn 7, Issue 310, 2014, Pages

Biasing GPCR signaling from inside

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; HUMANS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84894505902     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005021     Document Type: Short Survey
Times cited : (41)

References (14)
  • 3
    • 80052359992 scopus 로고    scopus 로고
    • Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
    • A. K. Shukla, K. Xiao, R. J. Lefkowitz, Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem. Sci. 36, 457-469 (2011).
    • (2011) Trends Biochem. Sci. , vol.36 , pp. 457-469
    • Shukla, A.K.1    Xiao, K.2    Lefkowitz, R.J.3
  • 4
    • 84875227396 scopus 로고    scopus 로고
    • Signalling bias in new drug discovery: Detection, quantification and therapeutic impact
    • T. Kenakin, A. Christopoulos, Signalling bias in new drug discovery: Detection, quantification and therapeutic impact. Nat. Rev. Drug Discov. 12, 205-216 (2013).
    • (2013) Nat. Rev. Drug Discov. , vol.12 , pp. 205-216
    • Kenakin, T.1    Christopoulos, A.2
  • 7
    • 0036797590 scopus 로고    scopus 로고
    • Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
    • L. Covic, M. Misra, J. Badar, C. Singh, A. Kuliopulos, Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation. Nat. Med. 8, 1161-1165 (2002).
    • (2002) Nat. Med. , vol.8 , pp. 1161-1165
    • Covic, L.1    Misra, M.2    Badar, J.3    Singh, C.4    Kuliopulos, A.5
  • 8
    • 80052083563 scopus 로고    scopus 로고
    • Nanobody stabilization of G protein-coupled receptor conformational states
    • J. Steyaert, B. K. Kobilka, Nanobody stabilization of G protein-coupled receptor conformational states. Curr. Opin. Struct. Biol. 21, 567-572 (2011).
    • (2011) Curr. Opin. Struct. Biol. , vol.21 , pp. 567-572
    • Steyaert, J.1    Kobilka, B.K.2
  • 9
    • 0025352299 scopus 로고
    • β-Arrestin: A protein that regulates β-adrenergic receptor function
    • M. J. Lohse, J. L. Benovic, J. Codina, M. G. Caron, R. J. Lefkowitz, β-Arrestin: A protein that regulates β-adrenergic receptor function. Science 248, 1547-1550 (1990).
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 10
    • 79959851876 scopus 로고    scopus 로고
    • A roadmap to generate renewable protein binders to the human proteome
    • Renewable Protein Binder Working Group
    • K. Colwill, S. Gräslund: Renewable Protein Binder Working Group, A roadmap to generate renewable protein binders to the human proteome. Nat. Methods 8, 551-558 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 551-558
    • Colwill, K.1    Gräslund, S.2
  • 12
    • 84891839423 scopus 로고    scopus 로고
    • Structural and functional analysis of G protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog
    • K. T. Homan, E. Wu, M. W. Wilson, P. Singh, S. D. Larsen, J. J. Tesmer, Structural and functional analysis of G protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. Mol. Pharmacol. 85, 237-248 (2014).
    • (2014) Mol. Pharmacol. , vol.85 , pp. 237-248
    • Homan, K.T.1    Wu, E.2    Wilson, M.W.3    Singh, P.4    Larsen, S.D.5    Tesmer, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.