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Volumn 86, Issue , 2014, Pages 562-569

Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2 H -chromene derivatives as potent anti-breast cancer agents

(10) Rahmani Nezhad, Samira a Safavi, Maliheh b Pordeli, Mahboobeh c Ardestani, Sussan Kabudanian c Khosravani, Leila a Pourshojaei, Yaghoub a Mahdavi, Mohammad a Emami, Saeed d Foroumadi, Alireza a Shafiee, Abbas a

a TEHRAN UNIVERSITY OF MEDICAL SCIENCES (Iran)

b IRANIAN RESEARCH ORGANIZATION FOR SCIENCE AND TECHNOLOGY IROST (Iran)

c UNIVERSITY OF TEHRAN (Iran)

d MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES (Iran)

Author keywords

2H chromene; Anti cancer agents; Apoptosis; Caspase 3; Nitrostyrene

Indexed keywords

2 ARYL 3 NITRO 2H CHROMENE DERIVATIVE; 3 NITRO 2 (3,4 DIMETHOXYPHENYL) 2H CHROMENE; 3 NITRO 2 (3,4 METHYLENEDIOXYPHENYL) 2H CHROMENE; 3 NITRO 2 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMENE; 3 NITRO 2 (4 CHLOROPHENYL) 2H CHROMENE; 3 NITRO 2 (4 METHOXYPHENYL) 2H CHROMENE; 3 NITRO 2 (4 METHYLPHENYL) 2H CHROMENE; 3 NITRO 2 (4 NITROPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (3,4 DIMETHOXYPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (3,4 METHYLENEDIOXYPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (4 CHLOROPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (4 METHOXYPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (4 METHYLPHENYL) 2H CHROMENE; 6,7,8 TRIMETHOXY 3 NITRO 2 (4 NITROPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (3,4 DIMETHOXYPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (3,4 METHYLENEDIOXYPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (4 CHLOROPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (4 METHOXYPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (4 METHYLPHENYL) 2H CHROMENE; 8 METHOXY 3 NITRO 2 (4 NITROPHENYL) 2H CHROMENE; ANTINEOPLASTIC AGENT; CHROMENE DERIVATIVE; UNCLASSIFIED DRUG; CHROMAN DERIVATIVE;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MCF 7 CELL LINE; MDA MB 231 CELL LINE; T 47D CELL LINE; BREAST NEOPLASMS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; FEMALE; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMANS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84907814906 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2014.09.017 Document Type: Article

Times cited : (100)

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