Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents

Journal of Medicinal Chemistry

Volumn 54, Issue 19, 2011, Pages 6751-6760

  Reddy, M Amarnath ^a   Jain, Nishant ^a   Yada, Deepthi ^a   Kishore, Chandan ^a   Vangala, Janakiram Reddy ^a   P Surendra, Reddy ^a   Addlagatta, Anthony ^a   Kalivendi, Shasi V ^a   Sreedhar, Bojja ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIMETHOXY 4 (4 METHOXYSTYRYL) 5 (2 NITROVINYL)BENZENE; 1,2,3 TRIMETHOXY 5 (2 NITROVINYL) 4 (3,4,5 TRIMETHOXYSTYRYL)BENZENE; 1,2,3 TRIMETHOXY 5 (2 NITROVINYL) 4 STYRYLBENZENE; 2 (3,5 DIMETHOXYSTYRYL) 3,4,5 TRIMETHOXY 1 (2 NITROVINYL)BENZENE; 2 (4 BROMOSTYRYL) 3,4,5 TRIMETHOXY 1 (2 NITROVINYL)BENZENE; 2 (4 CHLOROSTYRYL) 3,4,5 TRIMETHOXY 1 (2 NITROVINYL)BENZENE; 2 (4 FUOROSTYRYL) 3,4,5 TRIMETHOXY 1 (2 NITROVINYL)BENZENE; 2 [2,3,4 TRIMETHOXY 6 (2 NITROVINYL)STYRYL]NAPHTHALENE; 3,4,5 TRIMETHOXY 4 (4 METHYLSTYRYL) 5 (2 NITROVINYL)BENZENE; 4 [2,3,4 TRIMETHOXY 6 (2 NITROVINYL)STYRYL]BIPHENYL; 5 [2,3,4 TRIMETHOXY 6 (2 NITROVINYL)STYRYL]BENZO[D][1,3]DIOXOLE; ANTIMITOTIC AGENT; CASPASE 3; COLCHICINE; NITRO DERIVATIVE; RESVERATROL; STILBENE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CYTOTOXICITY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; HYDROGEN BOND; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MICROTUBULE; MOLECULAR DOCKING; PROTEIN ASSEMBLY; PROTEIN POLYMERIZATION;

ANTIMITOTIC AGENTS; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL NUCLEUS; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HUMANS; MICROTUBULES; MODELS, MOLECULAR; NITRO COMPOUNDS; STEREOISOMERISM; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN MODULATORS; VINYL COMPOUNDS;

EID: 80053896215     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200639r     Document Type: Article

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