A secondary structural transition in the C-helix promotes gating of cyclic nucleotide-regulated ion channels

Journal of Biological Chemistry

Volumn 288, Issue 18, 2013, Pages 12944-12956

  Puljung, Michael C ^a   Zagotta, William N ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; FLUOROPHORES; METAL IONS; TRANSITION METAL COMPOUNDS; TRANSITION METALS;

C-TERMINAL DOMAINS; C-TERMINAL FRAGMENTS; CHANNEL OPENING; CONFORMATIONAL CHANGE; CYCLIC NUCLEOTIDE; METAL BINDING AFFINITY; SECOND MESSENGER; STRUCTURAL TRANSITIONS;

NUCLEOTIDES;

COBALT; CYCLIC AMP; CYCLIC NUCLEOTIDE REGULATED ION CHANNEL; HISTIDINE; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE MODULATED CHANNEL; ION CHANNEL; NICKEL; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; METAL BINDING; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

EID: 84877132586     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.464123     Document Type: Article

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