Abnormalities in the zinc-metalloprotease-BDNF axis may contribute to megalencephaly and cortical hyperconnectivity in young autism spectrum disorder patients

Molecular Brain

Volumn 7, Issue 1, 2014, Pages

  Koh, Jae Young ^a   Lim, Joon Seo ^a   Byun, Hyae Ran ^a   Yoo, Min Heui ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Autism spectrum disorder (ASD); Brain derived neurotrophic factor (BDNF); Metalloprotease; Zinc

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LIPOPOLYSACCHARIDE; METALLOPROTEINASE; PROTEIN TYROSINE KINASE; TOPICAL ANTIINFECTIVE AGENT; ZINC;

ALEXANDER DISEASE; ANALYTICAL PARAMETERS; ARTICLE; AUTISM; BRAIN SIZE; CONNECTOME; CORTICAL HYPERCONNECTIVITY; DOWN REGULATION; EXTRACELLULAR ZINC; FLUORESCENCE; FOREBRAIN; FRAGILE X SYNDROME; GENE MUTATION; GENE PRODUCT; HUMAN; MESENCEPHALON; NONHUMAN; SECOND CERVICAL VERTEBRA; SIGNAL TRANSDUCTION; SYNAPSE VESICLE; UPREGULATION; WESTERN BLOTTING; ZINC METALLOPROTEASE BRAIN DERIVED NEUROTROPHIC FACTOR AXIS; ZYMOGRAPHY; BRAIN CORTEX; ENZYMOLOGY; METABOLISM; NERVE CELL NETWORK; PATHOLOGY; PATHOPHYSIOLOGY;

BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; CHILD DEVELOPMENT DISORDERS, PERVASIVE; HUMANS; MEGALENCEPHALY; METALLOPROTEASES; NERVE NET; ZINC;

EID: 84907585603     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/s13041-014-0064-z     Document Type: Article

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