Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance

Biochemical and Biophysical Research Communications

Volumn 452, Issue 3, 2014, Pages 669-675

  Han, Seong Su ^a   Han, Sangwoo ^a   Kamberos, Natalie L ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

B acute lymphoblastic leukemia; GC resistance; Piperlongumine; Transcription factors

Indexed keywords

ALKALOID DERIVATIVE; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PIPERLONGUMINE; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; STAT3 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; ANTINEOPLASTIC AGENT; AURKB PROTEIN, HUMAN; AURORA B KINASE; BIRC5 PROTEIN, HUMAN; DNA BINDING PROTEIN; E2F1 PROTEIN, HUMAN; GLUCOCORTICOID; INHIBITOR OF APOPTOSIS PROTEIN; PIPERLONGUMININE; PROTEIN C MYB; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SOX4 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR SOX; TUMOR PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; B CELL LEUKEMIA; CELL PROLIFERATION; CELL SURVIVAL; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; APOPTOSIS; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; PIPER (PLANT); SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AURORA KINASE B; CELL LINE, TUMOR; CELL PROLIFERATION; DEXAMETHASONE; DIOXOLANES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, LEUKEMIC; GLUCOCORTICOIDS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; NEOPLASM PROTEINS; PIPER; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-MYB; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SOXC TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS;

EID: 84907536932     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.131     Document Type: Article

References (33)

1. H. Inaba, M. Greaves, and C.G. Mullighan Acute lymphoblastic leukaemia Lancet 381 2013 1943 1955
2. C.G. Mullighan Genomic characterization of childhood acute lymphoblastic leukemia Semin. Hematol. 50 4 2013 314 324
3. G.J.L. Kaspers, R. Pieters, E. Klumper, F.C. De Waal, and A.J.P. Veerman Glucocorticoid resistance in childhood leukaemia Leuk. Lymphoma 13 1994 187 201
4. N.P. Gullett, A.R. Ruhul Amin, S. Bayraktar, J.M. Pezzuto, D.M. Shin, F.R. Khuri, B.B. Aggarwal, Y.J. Surh, and O. Kucuk Cancer prevention with natural compounds Semin. Oncol. 37 2010 258 281
5. K.W. Lee, A.M. Bode, and Z. Dong Molecular targets of phytochemicals for cancer prevention Nat. Rev. Cancer 11 2011 211 218
6. S. Kumar, J. Kamboj, Suman, and S. Sharma Overview for various aspects of the health benefits of Piper longum linn. fruit J. Acupunct. Meridian Stud. 4 2011 134 140
7. N. Singh, S. Kumar, P. Singh, H.G. Raj, A.K. Prasad, V.S. Parmar, and B. Ghosh Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation Phytomedicine 15 2008 284 291
8. L. Raj, T. Ide, A.U. Gurkar, M. Foley, M. Schenone, X. Li, N.J. Tolliday, T.R. Golub, S.A. Carr, A.F. Shamji, A.M. Stern, A. Mandinova, S.L. Schreiber, and S.W. Lee Selective killing of cancer cells by a small molecule targeting the stress response to ROS Nature 475 2011 231 234
9. S.S. Han, D.J. Son, H. Yun, N.L. Kamberos, and S. Janz Piperlongumine inhibits proliferation and survival of Burkitt lymphoma in vitro Leuk. Res. 37 2013 146 154
10. S.S. Han, V.S. Tompkins, D.J. Son, N.L. Kamberos, L.L. Stunz, A. Halwani, G.A. Bishop, and S. Janz Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells Biochem. Biophys. Res. Commun. 436 4 2013 660 665
11. J. O'Neil, and A.T. Look Mechanisms of transcription factor deregulation in lymphoid cell transformation Oncogene 26 47 2007 6838 6849
12. S. Bailey, A.G. Hall, A.D. Pearson, and C.P. Redfern The role of AP-1 in glucocorticoid resistance in leukaemia Leukemia 15 3 2001 391 397
13. H. Wang, Y. Yang, N. Sharma, N.I. Tarasova, O.A. Timofeeva, R.T. Winkler-Pickett, S. Tanigawa, and A.O. Perantoni STAT1 activation regulates proliferation and differentiation of renal progenitors Cell Signal 22 11 2010 1717 1726
14. A. Zaravinos, and D.A. Spandidos Yin yang 1 expression in human tumors Cell Cycle (Georgetown, Tex) 9 2010 512 522
15. S.S. Han, H. Yun, D.J. Son, V.S. Tompkins, L. Peng, S.T. Chung, J.S. Kim, E.S. Park, and S. Janz NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma Mol. Cancer 9 2010 97
16. V. Potluri, S.K. Noothi, S.D. Vallabhapurapu, S.O. Yoon, J.J. Driscoll, C.H. Lawrie, and S. Vallabhapurapu Transcriptional repression of Bim by a novel YY1-relA complex is essential for the survival and growth of multiple myeloma PLoS one 8 2013 e66121
17. S.J. Vervoort, R. van Boxtel, and P.J. Coffer The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe? Oncogene 32 29 2013 3397 3409
18. B. Goldenson, and J.D. Crispino The aurora kinases in cell cycle and leukemia Oncogene 2014 1 9
19. K.C.H. Athanasoula, H. Gogas, K. Polonifi, A.G. Vaiopoulos, A. Polyzos, and M. Mantzourani Survivin beyond physiology: orchestration of multistep carcinogenesis and therapeutic potentials Cancer Lett. 347 2 2014 175 182
20. A. Oke, D. Pearce, R.W. Wilkinson, C. Crafter, R. Odedra, J. Cavenagh, J. Fitzgibbon, A.T. Lister, S. Joel, and D. Bonnet AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo Cancer Res. 69 2009 4150 4158
21. C. Zheng, Z. Ren, H. Wang, W. Zhang, D.V. Kalvakolanu, Z. Tian, and W. Xiao E2F1 Induces tumor cell survival via nuclear factor-kappaB-dependent induction of EGR1 transcription in prostate cancer cells Cancer Res. 69 2009 2324 2331
22. C.R. Toth, R.F. Hostutler, A.S. Baldwin Jr., and T.P. Bender Members of the nuclear factor kappa B family transactivate the murine c-myb gene J. Biol. Chem. 270 1995 7661 7671
23. H. Zhou, M.Q. Du, and V.M. Dixit Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity Cancer Cell 7 2005 425 431
24. S.G. Ahn, H.S. Kim, S.W. Jeong, B.E. Kim, H. Rhim, J.Y. Shim, J.W. Kim, J.H. Lee, and I.K. Kim Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A(2) and delta(12)-PGJ(2) Exp. Mol. Med. 34 2002 243 249
25. S.M. Jafarnejad, A.A. Wani, M. Martinka, and G. Li Prognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion Am. J. Pathol. 177 2010 2741 2752
26. H. Ikushima, T. Todo, Y. Ino, M. Takahashi, N. Saito, K. Miyazawa, and K. Miyazono Glioma-initiating cells retain their tumorigenicity through integration of the Sox axis and Oct4 protein J. Biol. Chem. 286 2011 41434 41441
27. Q. Duan, X. Wang, W. Gong, L. Ni, C. Chen, X. He, F. Chen, L. Yang, P. Wang, and D.W. Wang ER stress negatively modulates the expression of the mir-199a/214 cluster to regulate tumor survival and progression in human hepatocellular cancer PLoS one 7 2012 e31518
28. L. Niederreiter, T.M. Fritz, T.E. Adolph, A.M. Krismer, F.A. Offner, M. Tschurtschenthaler, M.B. Flak, S. Hosomi, M.F. Tomczak, N.C. Kaneider, E. Sarcevic, S.L. Kempster, T. Raine, D. Esser, P. Rosenstiel, K. Kohno, T. Iwawaki, H. Tilg, R.S. Blumberg, and A. Kaser ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells J. Exp. Med. 210 10 2013 2041 2056
29. O. Krizanova, I. Steliarova, L. Csaderova, M. Pastorek, and S. Hudecova Capsaicin induces apoptosis in PC12 cells through ER stress Oncol. Rep. 31 2 2014 581 588
30. J.I. Yook, and J. Kim Expression of p21WAF1/CIP1 is unrelated to p53 tumour suppressor gene status in oral squamous cell carcinomas Oral Oncol. 34 1998 198 203
31. A. Viale, F. De Franco, A. Orleth, V. Cambiaghi, V. Giuliani, D. Bossi, C. Ronchini, S. Ronzoni, I. Muradore, and S. Monestiroli Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells Nature 457 2009 51 56
32. G.D. Bren, N.J. Solan, H. Miyoshi, K.N. Pennington, L.J. Pobst, and C.V. Paya Transcription of the RelB gene is regulated by NF-kappaB Oncogene 20 2001 7722 7733
33. T. Abbas, and A. Dutta P21 in cancer: intricate networks and multiple activities Nat. Rev. Cancer 9 2009 400 414