메뉴 건너뛰기




Volumn 347, Issue 2, 2014, Pages 175-182

Survivin beyond physiology: Orchestration of multistep carcinogenesis and therapeutic potentials

Author keywords

Anti apoptotic protein; Cancer; IAP family; Survivin; Targeted therapy

Indexed keywords

CARBOPLATIN; DOCETAXEL; GATAPARSEN; PACLITAXEL; PREDNISONE; SEPANTRONIUM BROMIDE; SMALL INTERFERING RNA; SURVIVIN; TERAMEPROCOL;

EID: 84898444850     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.02.014     Document Type: Review
Times cited : (57)

References (104)
  • 1
  • 3
    • 35948950248 scopus 로고    scopus 로고
    • The inhibitor of apoptosis proteins as therapeutic targets in cancer
    • Vucic D., Fairbrother W.J. The inhibitor of apoptosis proteins as therapeutic targets in cancer. Clin. Cancer Res. 2007, 13:5995-6000.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5995-6000
    • Vucic, D.1    Fairbrother, W.J.2
  • 5
    • 50149115578 scopus 로고    scopus 로고
    • Cancer cells survive with survivin
    • Yamamoto H., Ngan C.Y., Monden M. Cancer cells survive with survivin. Cancer Sci. 2008, 99:1709-1714.
    • (2008) Cancer Sci. , vol.99 , pp. 1709-1714
    • Yamamoto, H.1    Ngan, C.Y.2    Monden, M.3
  • 6
    • 79953655787 scopus 로고    scopus 로고
    • Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin
    • Kelly R.J., Lopez-Chavez A., Citrin D., Janik J.E., Morris J.C. Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin. Mol. Cancer 2011, 10:35.
    • (2011) Mol. Cancer , vol.10 , pp. 35
    • Kelly, R.J.1    Lopez-Chavez, A.2    Citrin, D.3    Janik, J.E.4    Morris, J.C.5
  • 9
    • 33846925495 scopus 로고    scopus 로고
    • Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis
    • Caldas H., Fangusaro J.R., Boue D.R., Holloway M.P., Altura R.A. Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis. Blood 2007, 109:1479-1489.
    • (2007) Blood , vol.109 , pp. 1479-1489
    • Caldas, H.1    Fangusaro, J.R.2    Boue, D.R.3    Holloway, M.P.4    Altura, R.A.5
  • 10
    • 33644854070 scopus 로고    scopus 로고
    • Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis
    • Noton E.A., Colnaghi R., Tate S., Starck C., Carvalho A., Ko Ferrigno P., Wheatley S.P. Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis. J. Biol. Chem. 2006, 281:1286-1295.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1286-1295
    • Noton, E.A.1    Colnaghi, R.2    Tate, S.3    Starck, C.4    Carvalho, A.5    Ko Ferrigno, P.6    Wheatley, S.P.7
  • 12
    • 22144438181 scopus 로고    scopus 로고
    • Survivin 2alpha: a novel survivin splice variant expressed in human malignancies
    • Caldas H., Honsey L.E., Altura R.A. Survivin 2alpha: a novel survivin splice variant expressed in human malignancies. Mol. Cancer 2005, 4:11.
    • (2005) Mol. Cancer , vol.4 , pp. 11
    • Caldas, H.1    Honsey, L.E.2    Altura, R.A.3
  • 15
    • 85050577976 scopus 로고    scopus 로고
    • Levels of effectiveness of gene therapies targeting survivin and its splice variants in human breast cancer cells
    • Zheng W.Y., Kang Y.Y., Li L.F., Xu Y.X., Ma X.Y. Levels of effectiveness of gene therapies targeting survivin and its splice variants in human breast cancer cells. Drug Discov. Ther. 2011, 5:293-298.
    • (2011) Drug Discov. Ther. , vol.5 , pp. 293-298
    • Zheng, W.Y.1    Kang, Y.Y.2    Li, L.F.3    Xu, Y.X.4    Ma, X.Y.5
  • 17
    • 33749256649 scopus 로고    scopus 로고
    • Structural, functional and therapeutic biology of survivin
    • Sah N.K., Khan Z., Khan G.J., Bisen P.S. Structural, functional and therapeutic biology of survivin. Cancer Lett. 2006, 244:164-171.
    • (2006) Cancer Lett. , vol.244 , pp. 164-171
    • Sah, N.K.1    Khan, Z.2    Khan, G.J.3    Bisen, P.S.4
  • 18
    • 54249129774 scopus 로고    scopus 로고
    • New wirings in the survivin networks
    • Altieri D.C. New wirings in the survivin networks. Oncogene 2008, 27:6276-6284.
    • (2008) Oncogene , vol.27 , pp. 6276-6284
    • Altieri, D.C.1
  • 19
    • 0031984247 scopus 로고    scopus 로고
    • Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation
    • Adida C., Crotty P.L., McGrath J., Berrebi D., Diebold J., Altieri D.C. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am. J. Pathol. 1998, 152:43-49.
    • (1998) Am. J. Pathol. , vol.152 , pp. 43-49
    • Adida, C.1    Crotty, P.L.2    McGrath, J.3    Berrebi, D.4    Diebold, J.5    Altieri, D.C.6
  • 20
    • 0034597594 scopus 로고    scopus 로고
    • Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
    • Uren A.G., Wong L., Pakusch M., Fowler K.J., Burrows F.J., Vaux D.L., Choo K.H. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 2000, 10:1319-1328.
    • (2000) Curr. Biol. , vol.10 , pp. 1319-1328
    • Uren, A.G.1    Wong, L.2    Pakusch, M.3    Fowler, K.J.4    Burrows, F.J.5    Vaux, D.L.6    Choo, K.H.7
  • 21
    • 71849093812 scopus 로고    scopus 로고
    • Survivin as an immunotherapeutic target for adult and pediatric malignant brain tumors
    • Liu R., Mitchell D.A. Survivin as an immunotherapeutic target for adult and pediatric malignant brain tumors. Cancer Immunol. Immunother. 2010, 59:183-193.
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 183-193
    • Liu, R.1    Mitchell, D.A.2
  • 22
    • 80052255348 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell death
    • Chowdhury S., Howell G.M., Teggart C.A., Chowdhury A., Person J.J., Bowers D.M., Brattain M.G. Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell death. J. Biol. Chem. 2011, 286:30937-30948.
    • (2011) J. Biol. Chem. , vol.286 , pp. 30937-30948
    • Chowdhury, S.1    Howell, G.M.2    Teggart, C.A.3    Chowdhury, A.4    Person, J.J.5    Bowers, D.M.6    Brattain, M.G.7
  • 24
    • 33745087154 scopus 로고    scopus 로고
    • Survivin, a cancer target with an emerging role in normal adult tissues
    • Fukuda S., Pelus L.M. Survivin, a cancer target with an emerging role in normal adult tissues. Mol. Cancer Ther. 2006, 5:1087-1098.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1087-1098
    • Fukuda, S.1    Pelus, L.M.2
  • 27
  • 28
    • 25444484909 scopus 로고    scopus 로고
    • Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis
    • Bokarewa M., Lindblad S., Bokarew D., Tarkowski A. Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis. Arthritis Res. Ther. 2005, 7:R349-R358.
    • (2005) Arthritis Res. Ther. , vol.7
    • Bokarewa, M.1    Lindblad, S.2    Bokarew, D.3    Tarkowski, A.4
  • 29
    • 84874816606 scopus 로고    scopus 로고
    • Expression of survivin and its four splice variants in colorectal cancer and its clinical significances
    • Ge Q.X., Li Y.Y., Nie Y.Q., Zuo W.G., Du Y.L. Expression of survivin and its four splice variants in colorectal cancer and its clinical significances. Med. Oncol. 2013, 30:535.
    • (2013) Med. Oncol. , vol.30 , pp. 535
    • Ge, Q.X.1    Li, Y.Y.2    Nie, Y.Q.3    Zuo, W.G.4    Du, Y.L.5
  • 30
    • 4544334875 scopus 로고    scopus 로고
    • Survivin regulates the p53 tumor suppressor gene family
    • Wang Z., Fukuda S., Pelus L.M. Survivin regulates the p53 tumor suppressor gene family. Oncogene 2004, 23:8146-8153.
    • (2004) Oncogene , vol.23 , pp. 8146-8153
    • Wang, Z.1    Fukuda, S.2    Pelus, L.M.3
  • 31
    • 12844286057 scopus 로고    scopus 로고
    • Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters
    • Esteve P.O., Chin H.G., Pradhan S. Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters. Proc. Natl. Acad. Sci. USA 2005, 102:1000-1005.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1000-1005
    • Esteve, P.O.1    Chin, H.G.2    Pradhan, S.3
  • 32
    • 84896547804 scopus 로고    scopus 로고
    • Targeting survivin in cancer: novel drug development approaches
    • Groner B., Weiss A. Targeting survivin in cancer: novel drug development approaches. BioDrugs 2013.
    • (2013) BioDrugs
    • Groner, B.1    Weiss, A.2
  • 33
    • 84874686245 scopus 로고    scopus 로고
    • MicroRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway
    • Ma Q., Wang X., Li Z., Li B., Ma F., Peng L., Zhang Y., Xu A., Jiang B. MicroRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway. Oncol. Rep. 2013, 29:1652-1658.
    • (2013) Oncol. Rep. , vol.29 , pp. 1652-1658
    • Ma, Q.1    Wang, X.2    Li, Z.3    Li, B.4    Ma, F.5    Peng, L.6    Zhang, Y.7    Xu, A.8    Jiang, B.9
  • 36
    • 52649172153 scopus 로고    scopus 로고
    • Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics
    • Mita A.C., Mita M.M., Nawrocki S.T., Giles F.J. Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics. Clin. Cancer Res. 2008, 14:5000-5005.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5000-5005
    • Mita, A.C.1    Mita, M.M.2    Nawrocki, S.T.3    Giles, F.J.4
  • 41
    • 35348862523 scopus 로고    scopus 로고
    • Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together
    • Jeyaprakash A.A., Klein U.R., Lindner D., Ebert J., Nigg E.A., Conti E. Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell 2007, 131:271-285.
    • (2007) Cell , vol.131 , pp. 271-285
    • Jeyaprakash, A.A.1    Klein, U.R.2    Lindner, D.3    Ebert, J.4    Nigg, E.A.5    Conti, E.6
  • 42
    • 77957725753 scopus 로고    scopus 로고
    • Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B
    • Kelly A.E., Ghenoiu C., Xue J.Z., Zierhut C., Kimura H., Funabiki H. Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science 2010, 330:235-239.
    • (2010) Science , vol.330 , pp. 235-239
    • Kelly, A.E.1    Ghenoiu, C.2    Xue, J.Z.3    Zierhut, C.4    Kimura, H.5    Funabiki, H.6
  • 44
    • 33750611276 scopus 로고    scopus 로고
    • The case for survivin as a regulator of microtubule dynamics and cell-death decisions
    • Altieri D.C. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr. Opin. Cell Biol. 2006, 18:609-615.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 609-615
    • Altieri, D.C.1
  • 46
    • 41249097491 scopus 로고    scopus 로고
    • Nuclear survivin has reduced stability and is not cytoprotective
    • Connell C.M., Colnaghi R., Wheatley S.P. Nuclear survivin has reduced stability and is not cytoprotective. J. Biol. Chem. 2008, 283:3289-3296.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3289-3296
    • Connell, C.M.1    Colnaghi, R.2    Wheatley, S.P.3
  • 47
    • 9644278114 scopus 로고    scopus 로고
    • Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis
    • Dohi T., Beltrami E., Wall N.R., Plescia J., Altieri D.C. Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis. J Clin. Invest. 2004, 114:1117-1127.
    • (2004) J Clin. Invest. , vol.114 , pp. 1117-1127
    • Dohi, T.1    Beltrami, E.2    Wall, N.R.3    Plescia, J.4    Altieri, D.C.5
  • 48
    • 13844280932 scopus 로고    scopus 로고
    • Apoptosis in the development and treatment of cancer
    • Gerl R., Vaux D.L. Apoptosis in the development and treatment of cancer. Carcinogenesis 2005, 26:263-270.
    • (2005) Carcinogenesis , vol.26 , pp. 263-270
    • Gerl, R.1    Vaux, D.L.2
  • 51
    • 0942290423 scopus 로고    scopus 로고
    • Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells
    • Liu T., Brouha B., Grossman D. Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells. Oncogene 2004, 23:39-48.
    • (2004) Oncogene , vol.23 , pp. 39-48
    • Liu, T.1    Brouha, B.2    Grossman, D.3
  • 52
    • 77956680686 scopus 로고    scopus 로고
    • Survivin and IAP proteins in cell-death mechanisms
    • Altieri D.C. Survivin and IAP proteins in cell-death mechanisms. Biochem. J. 2010, 430:199-205.
    • (2010) Biochem. J. , vol.430 , pp. 199-205
    • Altieri, D.C.1
  • 53
    • 80052158404 scopus 로고    scopus 로고
    • Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells
    • Knight B.B., Oprea-Ilies G.M., Nagalingam A., Yang L., Cohen C., Saxena N.K., Sharma D. Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells. Endocr. Relat. Cancer 2011, 18:413-428.
    • (2011) Endocr. Relat. Cancer , vol.18 , pp. 413-428
    • Knight, B.B.1    Oprea-Ilies, G.M.2    Nagalingam, A.3    Yang, L.4    Cohen, C.5    Saxena, N.K.6    Sharma, D.7
  • 55
    • 78049267203 scopus 로고    scopus 로고
    • Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation
    • McKenzie J.A., Liu T., Goodson A.G., Grossman D. Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation. Cancer Res. 2010, 70:7927-7937.
    • (2010) Cancer Res. , vol.70 , pp. 7927-7937
    • McKenzie, J.A.1    Liu, T.2    Goodson, A.G.3    Grossman, D.4
  • 58
    • 38149074799 scopus 로고    scopus 로고
    • Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern
    • Mera S., Magnusson M., Tarkowski A., Bokarewa M. Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern. J. Leukoc. Biol. 2008, 83:149-155.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 149-155
    • Mera, S.1    Magnusson, M.2    Tarkowski, A.3    Bokarewa, M.4
  • 62
    • 84880872866 scopus 로고    scopus 로고
    • Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-kappaB expression in MCF-7/5-FU cells
    • Wang Q.P., Wang Y., Wang X.D., Mo X.M., Gu J., Lu Z.Y., Pan Z.L., Zhu Y.X. Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-kappaB expression in MCF-7/5-FU cells. Int. J. Biochem. Cell Biol. 2013, 45:2036-2044.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 2036-2044
    • Wang, Q.P.1    Wang, Y.2    Wang, X.D.3    Mo, X.M.4    Gu, J.5    Lu, Z.Y.6    Pan, Z.L.7    Zhu, Y.X.8
  • 64
    • 80051590837 scopus 로고    scopus 로고
    • High survivin expression as a predictor of poor response to preoperative chemoradiotherapy in locally advanced rectal cancer
    • Kim K., Chie E.K., Wu H.G., Kim S.G., Lee S.H., Kang G.H., Hyun C.L., Ha S.W. High survivin expression as a predictor of poor response to preoperative chemoradiotherapy in locally advanced rectal cancer. Int. J. Colorectal Dis. 2011, 26:1019-1023.
    • (2011) Int. J. Colorectal Dis. , vol.26 , pp. 1019-1023
    • Kim, K.1    Chie, E.K.2    Wu, H.G.3    Kim, S.G.4    Lee, S.H.5    Kang, G.H.6    Hyun, C.L.7    Ha, S.W.8
  • 66
    • 84885694720 scopus 로고    scopus 로고
    • Prognostic role of survivin in bladder cancer: a systematic review and meta-analysis
    • Jeon C., Kim M., Kwak C., Kim H.H., Ku J.H. Prognostic role of survivin in bladder cancer: a systematic review and meta-analysis. PLoS ONE 2013, 8:e76719.
    • (2013) PLoS ONE , vol.8
    • Jeon, C.1    Kim, M.2    Kwak, C.3    Kim, H.H.4    Ku, J.H.5
  • 67
    • 84896542537 scopus 로고    scopus 로고
    • Prognostic and clinicopathological significance of survivin expression in bladder cancer patients: a meta-analysis
    • Lv S., Turlova E., Zhao S., Kang H., Han M., Sun H.S. Prognostic and clinicopathological significance of survivin expression in bladder cancer patients: a meta-analysis. Tumour Biol. 2013.
    • (2013) Tumour Biol.
    • Lv, S.1    Turlova, E.2    Zhao, S.3    Kang, H.4    Han, M.5    Sun, H.S.6
  • 68
    • 84881462903 scopus 로고    scopus 로고
    • Prognostic value of survivin expression in breast cancer patients: a meta-analysis
    • Song J., Su H., Zhou Y.Y., Guo L.L. Prognostic value of survivin expression in breast cancer patients: a meta-analysis. Tumour Biol. 2013, 34:2053-2062.
    • (2013) Tumour Biol. , vol.34 , pp. 2053-2062
    • Song, J.1    Su, H.2    Zhou, Y.Y.3    Guo, L.L.4
  • 69
    • 84884133225 scopus 로고    scopus 로고
    • Survivin expression is an independent poor prognostic marker in lung adenocarcinoma but not in squamous cell carcinoma
    • Sun P.L., Jin Y., Kim H., Seo A.N., Jheon S., Lee C.T., Chung J.H. Survivin expression is an independent poor prognostic marker in lung adenocarcinoma but not in squamous cell carcinoma. Virchows Arch. 2013, 463:427-436.
    • (2013) Virchows Arch. , vol.463 , pp. 427-436
    • Sun, P.L.1    Jin, Y.2    Kim, H.3    Seo, A.N.4    Jheon, S.5    Lee, C.T.6    Chung, J.H.7
  • 71
    • 84880990385 scopus 로고    scopus 로고
    • Prognostic value of survivin in patients with gastric cancer: a systematic review with meta-analysis
    • Liu J.L., Gao W., Kang Q.M., Zhang X.J., Yang S.G. Prognostic value of survivin in patients with gastric cancer: a systematic review with meta-analysis. PLoS ONE 2013, 8:e71930.
    • (2013) PLoS ONE , vol.8
    • Liu, J.L.1    Gao, W.2    Kang, Q.M.3    Zhang, X.J.4    Yang, S.G.5
  • 73
    • 67349218868 scopus 로고    scopus 로고
    • Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance
    • Chen N., Gong J., Chen X., Meng W., Huang Y., Zhao F., Wang L., Zhou Q. Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance. Hum. Pathol. 2009, 40:950-956.
    • (2009) Hum. Pathol. , vol.40 , pp. 950-956
    • Chen, N.1    Gong, J.2    Chen, X.3    Meng, W.4    Huang, Y.5    Zhao, F.6    Wang, L.7    Zhou, Q.8
  • 74
    • 84865559988 scopus 로고    scopus 로고
    • Nuclear survivin expression is associated with a poor prognosis in Caucasian non-small cell lung cancer patients
    • Xie Y.L., An L., Jiang H., Wang J. Nuclear survivin expression is associated with a poor prognosis in Caucasian non-small cell lung cancer patients. Clin. Chim. Acta. 2012, 414:41-43.
    • (2012) Clin. Chim. Acta. , vol.414 , pp. 41-43
    • Xie, Y.L.1    An, L.2    Jiang, H.3    Wang, J.4
  • 78
    • 80053222302 scopus 로고    scopus 로고
    • Significant elevation of survivin and livin expression in human colorectal cancer: inverse correlation between expression and overall survival
    • Xi R.C., Biao W.S., Gang Z.Z. Significant elevation of survivin and livin expression in human colorectal cancer: inverse correlation between expression and overall survival. Onkologie 2011, 34:428-432.
    • (2011) Onkologie , vol.34 , pp. 428-432
    • Xi, R.C.1    Biao, W.S.2    Gang, Z.Z.3
  • 79
    • 84865311365 scopus 로고    scopus 로고
    • Urine survivin as a diagnostic biomarker for bladder cancer: a systematic review
    • Ku J.H., Godoy G., Amiel G.E., Lerner S.P. Urine survivin as a diagnostic biomarker for bladder cancer: a systematic review. BJU Int. 2012, 110:630-636.
    • (2012) BJU Int. , vol.110 , pp. 630-636
    • Ku, J.H.1    Godoy, G.2    Amiel, G.E.3    Lerner, S.P.4
  • 80
    • 84884472591 scopus 로고    scopus 로고
    • Monitoring survivin expression in cancer: implications for prognosis and therapy
    • Guindalini R.S., Mathias Machado M.C., Garicochea B. Monitoring survivin expression in cancer: implications for prognosis and therapy. Mol. Diagn. Ther. 2013, 17:331-342.
    • (2013) Mol. Diagn. Ther. , vol.17 , pp. 331-342
    • Guindalini, R.S.1    Mathias Machado, M.C.2    Garicochea, B.3
  • 81
    • 79958237620 scopus 로고    scopus 로고
    • Targeting survivin in cancer: the cell-signalling perspective
    • Kanwar J.R., Kamalapuram S.K., Kanwar R.K. Targeting survivin in cancer: the cell-signalling perspective. Drug Discov. Today 2011, 16:485-494.
    • (2011) Drug Discov. Today , vol.16 , pp. 485-494
    • Kanwar, J.R.1    Kamalapuram, S.K.2    Kanwar, R.K.3
  • 83
    • 84860862938 scopus 로고    scopus 로고
    • Survivin in solid tumors: rationale for development of inhibitors
    • Church D.N., Talbot D.C. Survivin in solid tumors: rationale for development of inhibitors. Curr. Oncol. Rep. 2012, 14:120-128.
    • (2012) Curr. Oncol. Rep. , vol.14 , pp. 120-128
    • Church, D.N.1    Talbot, D.C.2
  • 87
    • 70350234507 scopus 로고    scopus 로고
    • Survivin: a new target for anti-cancer therapy
    • Ryan B.M., O'Donovan N., Duffy M.J. Survivin: a new target for anti-cancer therapy. Cancer Treat. Rev. 2009, 35:553-562.
    • (2009) Cancer Treat. Rev. , vol.35 , pp. 553-562
    • Ryan, B.M.1    O'Donovan, N.2    Duffy, M.J.3
  • 88
    • 79961082146 scopus 로고    scopus 로고
    • Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents
    • Trabulo S., Cardoso A.M., Santos-Ferreira T., Cardoso A.L., Simoes S., Pedroso de Lima M.C. Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents. Mol. Pharm. 2011, 8:1120-1131.
    • (2011) Mol. Pharm. , vol.8 , pp. 1120-1131
    • Trabulo, S.1    Cardoso, A.M.2    Santos-Ferreira, T.3    Cardoso, A.L.4    Simoes, S.5    Pedroso de Lima, M.C.6
  • 89
    • 84861896545 scopus 로고    scopus 로고
    • Survivin-T34A: molecular mechanism and therapeutic potential
    • Aspe J.R., Wall N.R. Survivin-T34A: molecular mechanism and therapeutic potential. Onco Targets Ther. 2010, 3:247-254.
    • (2010) Onco Targets Ther. , vol.3 , pp. 247-254
    • Aspe, J.R.1    Wall, N.R.2
  • 90
    • 84880309736 scopus 로고    scopus 로고
    • Inhibition of gastric cancer cell growth in vivo by overexpression of adeno-associated virus-mediated survivin mutant C84A
    • Weng Y., Fei B., Chi A.L., Cai M. Inhibition of gastric cancer cell growth in vivo by overexpression of adeno-associated virus-mediated survivin mutant C84A. Oncol. Res. 2013, 20:411-417.
    • (2013) Oncol. Res. , vol.20 , pp. 411-417
    • Weng, Y.1    Fei, B.2    Chi, A.L.3    Cai, M.4
  • 93
    • 79951717493 scopus 로고    scopus 로고
    • Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models
    • Nakahara T., Kita A., Yamanaka K., Mori M., Amino N., Takeuchi M., Tominaga F., Kinoyama I., Matsuhisa A., Kudou M., Sasamata M. Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models. Cancer Sci. 2011, 102:614-621.
    • (2011) Cancer Sci. , vol.102 , pp. 614-621
    • Nakahara, T.1    Kita, A.2    Yamanaka, K.3    Mori, M.4    Amino, N.5    Takeuchi, M.6    Tominaga, F.7    Kinoyama, I.8    Matsuhisa, A.9    Kudou, M.10    Sasamata, M.11
  • 94
    • 84892618930 scopus 로고    scopus 로고
    • Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells
    • Kaneko N., Yamanaka K., Kita A., Tabata K., Akabane T., Mori M. Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells. Biol. Pharm. Bull. 2013, 36:1921-1927.
    • (2013) Biol. Pharm. Bull. , vol.36 , pp. 1921-1927
    • Kaneko, N.1    Yamanaka, K.2    Kita, A.3    Tabata, K.4    Akabane, T.5    Mori, M.6
  • 97
    • 79151481416 scopus 로고    scopus 로고
    • A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma
    • Lewis K.D., Samlowski W., Ward J., Catlett J., Cranmer L., Kirkwood J., Lawson D., Whitman E., Gonzalez R. A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma. Invest. New Drugs 2011, 29:161-166.
    • (2011) Invest. New Drugs , vol.29 , pp. 161-166
    • Lewis, K.D.1    Samlowski, W.2    Ward, J.3    Catlett, J.4    Cranmer, L.5    Kirkwood, J.6    Lawson, D.7    Whitman, E.8    Gonzalez, R.9
  • 98
    • 84859422180 scopus 로고    scopus 로고
    • A phase II study of YM155, a novel small-molecule suppressor of survivin, in castration-resistant taxane-pretreated prostate cancer
    • Tolcher A.W., Quinn D.I., Ferrari A., Ahmann F., Giaccone G., Drake T., Keating A., de Bono J.S. A phase II study of YM155, a novel small-molecule suppressor of survivin, in castration-resistant taxane-pretreated prostate cancer. Ann. Oncol. 2012, 23:968-973.
    • (2012) Ann. Oncol. , vol.23 , pp. 968-973
    • Tolcher, A.W.1    Quinn, D.I.2    Ferrari, A.3    Ahmann, F.4    Giaccone, G.5    Drake, T.6    Keating, A.7    de Bono, J.S.8
  • 99
    • 36348998080 scopus 로고    scopus 로고
    • Phase I/II clinical safety studies of terameprocol vaginal ointment
    • Khanna N., Dalby R., Tan M., Arnold S., Stern J., Frazer N. Phase I/II clinical safety studies of terameprocol vaginal ointment. Gynecol. Oncol. 2007, 107:554-562.
    • (2007) Gynecol. Oncol. , vol.107 , pp. 554-562
    • Khanna, N.1    Dalby, R.2    Tan, M.3    Arnold, S.4    Stern, J.5    Frazer, N.6
  • 102
    • 84898437034 scopus 로고    scopus 로고
    • Survivin expression and targeting in breast cancer
    • Jha K., Shukla M., Pandey M. Survivin expression and targeting in breast cancer. Surg. Oncol. 2011.
    • (2011) Surg. Oncol.
    • Jha, K.1    Shukla, M.2    Pandey, M.3
  • 103
    • 84876096250 scopus 로고    scopus 로고
    • Targeting survivin in cancer
    • Altieri D.C. Targeting survivin in cancer. Cancer Lett. 2013, 332:225-228.
    • (2013) Cancer Lett. , vol.332 , pp. 225-228
    • Altieri, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.