-
1
-
-
79958235988
-
Stressed to death: Targeting endoplasmic reticulum stress response-induced apoptosis in gliomas
-
Johnson GG, White MC and Grimaldi M: Stressed to death: targeting endoplasmic reticulum stress response-induced apoptosis in gliomas. Curr Pharm Des 17: 284-292, 2011.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 284-292
-
-
Johnson, G.G.1
White, M.C.2
Grimaldi, M.3
-
2
-
-
80054026314
-
A review of the mammalian unfolded protein response
-
Chakrabarti A, Chen AW and Varner JD: A review of the mammalian unfolded protein response. Biotechnol Bioeng 108: 2777-2793, 2011.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 2777-2793
-
-
Chakrabarti, A.1
Chen, A.W.2
Varner, J.D.3
-
3
-
-
84874009582
-
Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma
-
Giubellino A, Sourbier C, Lee MJ, Scroggins B, Bullova P, Landau M, Ying W, Neckers L, Trepel JB and Pacak K: Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma. PLoS One 8: e56083, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Giubellino, A.1
Sourbier, C.2
Lee, M.J.3
Scroggins, B.4
Bullova, P.5
Landau, M.6
Ying, W.7
Neckers, L.8
Trepel, J.B.9
Pacak, K.10
-
4
-
-
77955044180
-
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction
-
Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C and Samal IA: HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction. PLoS Biol 8: e1000410, 2010.
-
(2010)
PLoS Biol
, vol.8
-
-
Gupta, S.1
Deepti, A.2
Deegan, S.3
Lisbona, F.4
Hetz, C.5
Samal, I.A.6
-
5
-
-
84857039457
-
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
-
Jhaveri K, Taldone T, Modi S and Chiosis G: Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. Biochim Biophys Acta 1823: 742-755, 2012.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 742-755
-
-
Jhaveri, K.1
Taldone, T.2
Modi, S.3
Chiosis, G.4
-
6
-
-
44049083639
-
Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: A breakthrough in anticancer therapy?
-
Labi V, Grespi F, Baumgartner F and Villunger A: Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? Cell Death Differ 15: 977-987, 2008.
-
(2008)
Cell Death Differ
, vol.15
, pp. 977-987
-
-
Labi, V.1
Grespi, F.2
Baumgartner, F.3
Villunger, A.4
-
7
-
-
35848969791
-
ER stress signaling and the BCL-2 family of proteins: From adaptation to irreversible cellular damage
-
Hetz AC: ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage. Antioxid Redox Signal 9: 2345-2355, 2007.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2345-2355
-
-
Hetz, A.C.1
-
8
-
-
84863414357
-
Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD
-
Saito Y, Tanaka Y, Aita Y, Ishii KA, Ikeda T, Isobe K, Kawakami Y, Shimano H, Hara H and Takekoshi K: Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD. Am J Physiol Endocrinol Metab 302: E615-E625, 2012.
-
(2012)
Am J Physiol Endocrinol Metab
, vol.302
-
-
Saito, Y.1
Tanaka, Y.2
Aita, Y.3
Ishii, K.A.4
Ikeda, T.5
Isobe, K.6
Kawakami, Y.7
Shimano, H.8
Hara, H.9
Takekoshi, K.10
-
9
-
-
84873809376
-
Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells
-
Ikeda T, Ishii KA, Saito Y, Miura M, Otagiri A, Kawakami Y, Shimano H, Hara H and Takekoshi K: Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells. J Pharmacol Sci 121: 67-73, 2013.
-
(2013)
J Pharmacol Sci
, vol.121
, pp. 67-73
-
-
Ikeda, T.1
Ishii, K.A.2
Saito, Y.3
Miura, M.4
Otagiri, A.5
Kawakami, Y.6
Shimano, H.7
Hara, H.8
Takekoshi, K.9
-
10
-
-
84877312967
-
Phyllanthus suppresses prostate cancer cell, PC-3, proliferation and induces apoptosis through multiple signalling pathways (MAPKs, PI3K/Akt, NFκB, and hypoxia)
-
Tang YQ, Jaganath I, Manikam R and Sekaran SD: Phyllanthus suppresses prostate cancer cell, PC-3, proliferation and induces apoptosis through multiple signalling pathways (MAPKs, PI3K/Akt, NFκB, and hypoxia). Evid Based Complement Alternat Med 2013: 609581, 2013.
-
(2013)
Evid Based Complement Alternat Med
, vol.2013
, pp. 609581
-
-
Tang, Y.Q.1
Jaganath, I.2
Manikam, R.3
Sekaran, S.D.4
-
11
-
-
84867070588
-
NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model
-
Pacak K, Sirova M, Giubellino A, Lencesova L, Csaderova L, Laukova M, Hudecova S and Krizanova O: NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model. Int J Cancer 131: 2445-2455, 2012.
-
(2012)
Int J Cancer
, vol.131
, pp. 2445-2455
-
-
Pacak, K.1
Sirova, M.2
Giubellino, A.3
Lencesova, L.4
Csaderova, L.5
Laukova, M.6
Hudecova, S.7
Krizanova, O.8
-
12
-
-
84872825262
-
Triptolide transcriptionally represses HER2 in ovarian cancer cells by targeting NF-κB
-
Ou CC, Chen YW, Hsu SC, Sytwu HK, Loh SH, Li JW and Liu JY: Triptolide transcriptionally represses HER2 in ovarian cancer cells by targeting NF-κB. Evid Based Complement Alternat Med 2012: 350239, 2012.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 350239
-
-
Ou, C.C.1
Chen, Y.W.2
Hsu, S.C.3
Sytwu, H.K.4
Loh, S.H.5
Li, J.W.6
Liu, J.Y.7
-
13
-
-
0842304283
-
Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: Implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
-
Ito K, Nakazato T, Yamato K, Myiakawa Y, Yamada T, Hozumi N, Segawa K, Ikeda Y and Kizaki M: Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species. Cancer Res 64: 1071-1078, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 1071-1078
-
-
Ito, K.1
Nakazato, T.2
Yamato, K.3
Myiakawa, Y.4
Yamada, T.5
Hozumi, N.6
Segawa, K.7
Ikeda, Y.8
Kizaki, M.9
-
14
-
-
84874637703
-
Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder
-
Santoni G, Caprodossi S, Farfariello V, Liberati S, Gismondi A and Amantini C: Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder. ISRN Urol 2012: 458238, 2012.
-
(2012)
ISRN Urol
, vol.2012
, pp. 458238
-
-
Santoni, G.1
Caprodossi, S.2
Farfariello, V.3
Liberati, S.4
Gismondi, A.5
Amantini, C.6
-
15
-
-
79955749422
-
Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells
-
Caprodossi S, Amantini C, Nabissi M, Morelli MB, Farfariello V, Santoni M, Gismondi A and Santoni G: Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells. Carcinogenesis 32: 686-694, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 686-694
-
-
Caprodossi, S.1
Amantini, C.2
Nabissi, M.3
Morelli, M.B.4
Farfariello, V.5
Santoni, M.6
Gismondi, A.7
Santoni, G.8
-
16
-
-
84878250751
-
Capsaicin mimics mechanical load-induced intracellular signaling events: Involvement of TRPV1-mediated calcium signaling in induction of skeletal muscle hypertrophy
-
Ito N, Ruegg UT, Kudo A, Miyagoe-Suzuki Y and Takeda S: Capsaicin mimics mechanical load-induced intracellular signaling events: involvement of TRPV1-mediated calcium signaling in induction of skeletal muscle hypertrophy. Channels 7: 221-224, 2013.
-
(2013)
Channels
, vol.7
, pp. 221-224
-
-
Ito, N.1
Ruegg, U.T.2
Kudo, A.3
Miyagoe-Suzuki, Y.4
Takeda, S.5
-
17
-
-
84880332454
-
Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2
-
Lencesova L, Hudecova S, Csaderova L, Markova J, Soltysova A, Pastorek M, Sedlak J, Wood ME, Whiteman M, Ondrias K and Krizanova O: Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2. Acta Physiol 208: 350-361, 2013.
-
(2013)
Acta Physiol
, vol.208
, pp. 350-361
-
-
Lencesova, L.1
Hudecova, S.2
Csaderova, L.3
Markova, J.4
Soltysova, A.5
Pastorek, M.6
Sedlak, J.7
Wood, M.E.8
Whiteman, M.9
Ondrias, K.10
Krizanova, O.11
-
18
-
-
0025257393
-
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes
-
Kalén A, Appelkvist EL and Dallner G: The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes. Chem Biol Interact 73: 221-234, 1989.
-
(1989)
Chem Biol Interact
, vol.73
, pp. 221-234
-
-
Kalén, A.1
Appelkvist, E.L.2
Dallner, G.3
-
20
-
-
23344431898
-
Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines
-
Jakubikova J, Bao Y and Sedlak J: Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res 25: 3375-3386, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 3375-3386
-
-
Jakubikova, J.1
Bao, Y.2
Sedlak, J.3
-
21
-
-
77955282104
-
Upregulation of Bcl2 inhibits apoptosis- driven BAX insertion but favors BAX relocalization in mitochondria
-
Teijido O and Dejean L: Upregulation of Bcl2 inhibits apoptosis- driven BAX insertion but favors BAX relocalization in mitochondria. FEBS Lett 584: 3305-3310, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 3305-3310
-
-
Teijido, O.1
Dejean, L.2
-
22
-
-
58149296552
-
Tumor resistance to apoptosis
-
Fulda S: Tumor resistance to apoptosis. Int J Cancer 124: 511-515, 2009.
-
(2009)
Int J Cancer
, vol.124
, pp. 511-515
-
-
Fulda, S.1
-
23
-
-
0035895597
-
xIAP induces cell-cycle arrest and activates nuclear factor-κB: New survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells
-
Levkau B, Garton KJ, Ferri N, Kloke K, Nofer JR, Baba HA, Raines EW and Breithardt G: xIAP induces cell-cycle arrest and activates nuclear factor-κB: new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells. Circ Res 88: 282-290, 2001.
-
(2001)
Circ Res
, vol.88
, pp. 282-290
-
-
Levkau, B.1
Garton, K.J.2
Ferri, N.3
Kloke, K.4
Nofer, J.R.5
Baba, H.A.6
Raines, E.W.7
Breithardt, G.8
-
24
-
-
34147103855
-
One gene, many proteins: Alternative splicing of the ryanodine receptor gene adds novel functions to an already complex channel protein
-
Valdivia HH: One gene, many proteins: alternative splicing of the ryanodine receptor gene adds novel functions to an already complex channel protein. Circ Res 100: 761-763, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 761-763
-
-
Valdivia, H.H.1
-
25
-
-
84874830784
-
Characterization of functional TRPV1 channels in the sarcoplasmic reticulum of mouse skeletal muscle
-
Lotteau S, Ducreux S, Romestaing C, Legrand C and Van Coppenolle F: Characterization of functional TRPV1 channels in the sarcoplasmic reticulum of mouse skeletal muscle. PLoS One 8: e58673, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Lotteau, S.1
Ducreux, S.2
Romestaing, C.3
Legrand, C.4
Van Coppenolle, F.5
-
26
-
-
10344222124
-
The role of unfolded protein response in tumor development: Friend or foe?
-
Ma Y and Hendershot LM: The role of unfolded protein response in tumor development: friend or foe? Nat Rev Cancer 4: 966-977, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
27
-
-
8544283103
-
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
-
Yamaguchi H and Wang HG: CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 279: 45495-45502, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 45495-45502
-
-
Yamaguchi, H.1
Wang, H.G.2
-
28
-
-
45449095670
-
Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: A microarray study
-
Sánchez AM, Martínez-Botas J, Malagarie-Cazenave S, Olea N, Vara D, Lasunción MA and Díaz-Laviada I: Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: a microarray study. Biochem Biophys Res Commun 372: 785-791, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 785-791
-
-
Sánchez, A.M.1
Martínez-Botas, J.2
Malagarie-Cazenave, S.3
Olea, N.4
Vara, D.5
Lasunción, M.A.6
Díaz-Laviada, I.7
-
30
-
-
80052827034
-
Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses the pro-survival XBP1 signaling in human multiple myeloma cells
-
Wang FM, Galson DL, Roodman GD and Ouyang H: Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses the pro-survival XBP1 signaling in human multiple myeloma cells. Exp Hematol 39: 999-1006, 2011.
-
(2011)
Exp Hematol
, vol.39
, pp. 999-1006
-
-
Wang, F.M.1
Galson, D.L.2
Roodman, G.D.3
Ouyang, H.4
|