메뉴 건너뛰기




Volumn 51, Issue 5, 2014, Pages 263-279

Critical appraisal of inflammatory markers in cardiovascular risk stratification

Author keywords

Acute coronary syndrome; Coronary artery disease; CRP; Fibrinogen; GDF 15; Inflammation; Lp PLA2; MPO; Risk prediction

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; C REACTIVE PROTEIN; FIBRINOGEN; GROWTH DIFFERENTIATION FACTOR 15; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYELOPEROXIDASE; TROPONIN; BIOLOGICAL MARKER;

EID: 84907440848     PISSN: 10408363     EISSN: 1549781X     Source Type: Journal    
DOI: 10.3109/10408363.2014.913549     Document Type: Review
Times cited : (72)

References (127)
  • 1
    • 84893113465 scopus 로고    scopus 로고
    • Executive summary: Heart disease and stroke statistics-2014 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Executive summary: heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation 2014;129:399-410.
    • (2014) Circulation , vol.129 , pp. 399-410
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
    • Yusuf S, Hawken S, Ounpuu S, et al.; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004;364:937-52.
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3
  • 3
    • 34047096374 scopus 로고    scopus 로고
    • Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: Comparison of African American with white subjects - Atherosclerosis Risk in Communities Study
    • Hozawa A, Folsom AR, Sharrett AR, Chambless LE. Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects - Atherosclerosis Risk in Communities Study. Arch Intern Med 2007;167:573-9.
    • (2007) Arch Intern Med , vol.167 , pp. 573-579
    • Hozawa, A.1    Folsom, A.R.2    Sharrett, A.R.3    Chambless, L.E.4
  • 4
    • 0042697063 scopus 로고    scopus 로고
    • Prevalence of conventional risk factors in patients with coronary heart disease
    • Khot UN, Khot MB, Bajzer CT, et al. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 2003; 290:898-904.
    • (2003) JAMA , vol.290 , pp. 898-904
    • Khot, U.N.1    Khot, M.B.2    Bajzer, C.T.3
  • 5
    • 84867919717 scopus 로고    scopus 로고
    • Identifying novel biomarkers for cardiovascular disease risk prediction
    • Ge Y, Wang TJ. Identifying novel biomarkers for cardiovascular disease risk prediction. J Intern Med 2012;272:430-9.
    • (2012) J Intern Med , vol.272 , pp. 430-439
    • Ge, Y.1    Wang, T.J.2
  • 6
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999;340:115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 7
    • 84865485915 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol 2012;32:2045-51.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2045-2051
    • Libby, P.1
  • 8
    • 21144441360 scopus 로고    scopus 로고
    • Percutaneous coronary intervention triggers a systemic inflammatory response in patients treated for in-stent restenosis - Comparison with stable and unstable angina
    • Kozinski M, Krzewina-Kowalska A, Kubica J, et al. Percutaneous coronary intervention triggers a systemic inflammatory response in patients treated for in-stent restenosis - comparison with stable and unstable angina. Inflamm Res 2005;54:187-93.
    • (2005) Inflamm Res , vol.54 , pp. 187-193
    • Kozinski, M.1    Krzewina-Kowalska, A.2    Kubica, J.3
  • 9
    • 23844543663 scopus 로고    scopus 로고
    • Combined periprocedural evaluation of CRP and TNF-alpha enhances the prediction of clinical restenosis and major adverse cardiac events in patients undergoing percutaneous coronary interventions
    • Kubica J, Kozinski M, Krzewina-Kowalska A, et al. Combined periprocedural evaluation of CRP and TNF-alpha enhances the prediction of clinical restenosis and major adverse cardiac events in patients undergoing percutaneous coronary interventions. Int J Mol Med 2005;16:173-80.
    • (2005) Int J Mol Med , vol.16 , pp. 173-180
    • Kubica, J.1    Kozinski, M.2    Krzewina-Kowalska, A.3
  • 10
    • 2942701875 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis and implications for therapy
    • Paoletti R, Gotto Jr AM, Hajjar DP. Inflammation in atherosclerosis and implications for therapy. Circulation 2004;109:III20-6.
    • (2004) Circulation , vol.109 , pp. III20-III26
    • Paoletti, R.1    Gotto, A.M.2    Hajjar, D.P.3
  • 11
    • 33947716172 scopus 로고    scopus 로고
    • Endothelial function and dysfunction: Testing and clinical relevance
    • Deanfield JE, Halcox JP, Rabelink TJ. Endothelial function and dysfunction: testing and clinical relevance. Circulation 2007;115: 1285-95.
    • (2007) Circulation , vol.115 , pp. 1285-1295
    • Deanfield, J.E.1    Halcox, J.P.2    Rabelink, T.J.3
  • 12
    • 84865776903 scopus 로고    scopus 로고
    • Quantifying the accuracy of a diagnostic test or marker
    • Linnet K1, Bossuyt PM, Moons KG, Reitsma JB. Quantifying the accuracy of a diagnostic test or marker. Clin Chem 2012;58: 1292-301.
    • (2012) Clin Chem , vol.58 , pp. 1292-1301
    • Linnet, K.1    Bossuyt, P.M.2    Moons, K.G.3    Reitsma, J.B.4
  • 13
    • 84865728012 scopus 로고    scopus 로고
    • Quantifying the added value of a diagnostic test or marker
    • Moons KG1, de Groot JA, Linnet K, et al. Quantifying the added value of a diagnostic test or marker. Clin Chem 2012;58:1408-17.
    • (2012) Clin Chem , vol.58 , pp. 1408-1417
    • Moons, K.G.1    De Groot, J.A.2    Linnet, K.3
  • 14
    • 84879912527 scopus 로고    scopus 로고
    • Classical and novel biomarkers for cardiovascular risk prediction in the United States
    • Folsom AR. Classical and novel biomarkers for cardiovascular risk prediction in the United States. J Epidemiol 2013;23:158-62.
    • (2013) J Epidemiol , vol.23 , pp. 158-162
    • Folsom, A.R.1
  • 15
    • 84861905041 scopus 로고    scopus 로고
    • Circulating, imaging, and genetic biomarkers in cardiovascular risk prediction
    • Ge Y, Wang TJ. Circulating, imaging, and genetic biomarkers in cardiovascular risk prediction. Trends Cardiovasc Med 2011;21: 105-12.
    • (2011) Trends Cardiovasc Med , vol.21 , pp. 105-112
    • Ge, Y.1    Wang, T.J.2
  • 16
    • 78650041424 scopus 로고    scopus 로고
    • 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2010;56:e50-103.
    • (2010) J Am Coll Cardiol , vol.56 , pp. e50-103
    • Greenland, P.1    Alpert, J.S.2    Beller, G.A.3
  • 17
    • 59649106810 scopus 로고    scopus 로고
    • National Academy of Clinical Biochemistry Laboratory Medicine Practice guidelines: Emerging biomarkers for primary prevention of cardiovascular disease
    • Myers GL, Christenson RH, Cushman M, et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice guidelines: emerging biomarkers for primary prevention of cardiovascular disease. Clin Chem 2009;55:378-84.
    • (2009) Clin Chem , vol.55 , pp. 378-384
    • Myers, G.L.1    Christenson, R.H.2    Cushman, M.3
  • 18
    • 84862119222 scopus 로고    scopus 로고
    • European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts)
    • Perk J, De Backer G, Gohlke H, et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 2012;33: 1635-701.
    • (2012) Eur Heart J , vol.33 , pp. 1635-1701
    • Perk, J.1    De Backer, G.2    Gohlke, H.3
  • 19
    • 59649121465 scopus 로고    scopus 로고
    • C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study
    • Wilson PW, Pencina M, Jacques P, et al. C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes 2008;1:92-7.
    • (2008) Circ Cardiovasc Qual Outcomes , vol.1 , pp. 92-97
    • Wilson, P.W.1    Pencina, M.2    Jacques, P.3
  • 20
    • 67749101389 scopus 로고    scopus 로고
    • Does fibrinogen add to prediction of cardiovascular disease? Results from the Scottish Heart Health Extended Cohort Study
    • Woodward M, Tunstall-Pedoe H, Rumley A, et al. Does fibrinogen add to prediction of cardiovascular disease? Results from the Scottish Heart Health Extended Cohort Study. Br J Haematol 2009;146:442-6.
    • (2009) Br J Haematol , vol.146 , pp. 442-446
    • Woodward, M.1    Tunstall-Pedoe, H.2    Rumley, A.3
  • 21
    • 79952447132 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 activity improves risk discrimination of incident coronary heart disease among women
    • Hatoum IJ, Cook NR, Nelson JJ, et al. Lipoprotein-associated phospholipase A2 activity improves risk discrimination of incident coronary heart disease among women. Am Heart J 2011;161: 516-22.
    • (2011) Am Heart J , vol.161 , pp. 516-522
    • Hatoum, I.J.1    Cook, N.R.2    Nelson, J.J.3
  • 22
    • 79957496852 scopus 로고    scopus 로고
    • Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: The Rancho Bernardo Study
    • Daniels LB, Clopton P, Laughlin GA, et al. Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: the Rancho Bernardo Study. Circulation 2011;123:2101-10.
    • (2011) Circulation , vol.123 , pp. 2101-2110
    • Daniels, L.B.1    Clopton, P.2    Laughlin, G.A.3
  • 23
    • 84879726788 scopus 로고    scopus 로고
    • Change in growth differentiation factor 15 concentrations over time independently predicts mortality in community-dwelling elderly individuals
    • Eggers KM, Kempf T, Wallentin L, et al. Change in growth differentiation factor 15 concentrations over time independently predicts mortality in community-dwelling elderly individuals. Clin Chem 2013;59:1091-8.
    • (2013) Clin Chem , vol.59 , pp. 1091-1098
    • Eggers, K.M.1    Kempf, T.2    Wallentin, L.3
  • 24
    • 84863393862 scopus 로고    scopus 로고
    • Association of growth differentiation factor-15 with coronary atherosclerosis and mortality in a young, multiethnic population: Observations from the Dallas Heart Study
    • Rohatgi A, Patel P, Das SR, et al. Association of growth differentiation factor-15 with coronary atherosclerosis and mortality in a young, multiethnic population: observations from the Dallas Heart Study. Clin Chem 2012;58:172-82.
    • (2012) Clin Chem , vol.58 , pp. 172-182
    • Rohatgi, A.1    Patel, P.2    Das, S.R.3
  • 25
    • 22044446512 scopus 로고    scopus 로고
    • Local release of C-reactive protein from vulnerable plaque or coronary arterial wall injured by stenting
    • Inoue T, Kato T, Uchida T, et al. Local release of C-reactive protein from vulnerable plaque or coronary arterial wall injured by stenting. J Am Coll Cardiol 2005;46:239-45.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 239-245
    • Inoue, T.1    Kato, T.2    Uchida, T.3
  • 26
    • 0037309204 scopus 로고    scopus 로고
    • Involvement of C-reactive protein obtained by directional coronary atherectomy in plaque instability and developing restenosis in patients with stable or unstable angina pectoris
    • Ishikawa T, Hatakeyama K, Imamura T, et al. Involvement of C-reactive protein obtained by directional coronary atherectomy in plaque instability and developing restenosis in patients with stable or unstable angina pectoris. Am J Cardiol 2003;91: 287-92.
    • (2003) Am J Cardiol , vol.91 , pp. 287-292
    • Ishikawa, T.1    Hatakeyama, K.2    Imamura, T.3
  • 27
    • 85021062648 scopus 로고
    • Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus
    • Tillett WS, Francis T. Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus. J Exp Med 1930; 52:561-71.
    • (1930) J Exp Med , vol.52 , pp. 561-571
    • Tillett, W.S.1    Francis, T.2
  • 28
    • 0035864605 scopus 로고    scopus 로고
    • Familial and genetic determinants of systemic markers of inflammation: The NHLBI family heart study
    • Pankow JS, Folsom AR, Cushman M, et al. Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. Atherosclerosis 2001;154:681-9.
    • (2001) Atherosclerosis , vol.154 , pp. 681-689
    • Pankow, J.S.1    Folsom, A.R.2    Cushman, M.3
  • 29
    • 84887164442 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and atherosclerotic disease: From improved risk prediction to risk-guided therapy
    • Koenig W. High-sensitivity C-reactive protein and atherosclerotic disease: from improved risk prediction to risk-guided therapy. Int J Cardiol 2013;168:5126-34.
    • (2013) Int J Cardiol , vol.168 , pp. 5126-5134
    • Koenig, W.1
  • 30
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
    • Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
    • (1997) N Engl J Med , vol.336 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3
  • 31
    • 33745966838 scopus 로고    scopus 로고
    • Narrative review: Assessment of C-reactive protein in risk prediction for cardiovascular disease
    • Lloyd-Jones DM, Liu K, Tian L, et al. Narrative review: assessment of C-reactive protein in risk prediction for cardiovascular disease. Ann Intern Med 2006;145:35-42.
    • (2006) Ann Intern Med , vol.145 , pp. 35-42
    • Lloyd-Jones, D.M.1    Liu, K.2    Tian, L.3
  • 32
    • 84869061841 scopus 로고    scopus 로고
    • Value of C-reactive protein as a risk factor for acute coronary syndrome: A comparison with apolipoprotein concentrations and lipid profile
    • Krintus M, Kozinski M, Stefanska A, et al. Value of C-reactive protein as a risk factor for acute coronary syndrome: a comparison with apolipoprotein concentrations and lipid profile. Mediators Inflamm 2012;2012:419804.
    • (2012) Mediators Inflamm , vol.2012 , pp. 419804
    • Krintus, M.1    Kozinski, M.2    Stefanska, A.3
  • 33
    • 73449130797 scopus 로고    scopus 로고
    • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis
    • Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, Lowe G, et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010;375:132-40.
    • (2010) Lancet , vol.375 , pp. 132-140
    • Kaptoge, S.1    Di Angelantonio, E.2    Lowe, G.3
  • 34
    • 84867164377 scopus 로고    scopus 로고
    • C-reactive protein, fibrinogen, and cardiovascular disease prediction
    • Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, Pennells L, et al. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 2012;367: 1310-20.
    • (2012) N Engl J Med , vol.367 , pp. 1310-1320
    • Kaptoge, S.1    Di Angelantonio, E.2    Pennells, L.3
  • 35
    • 76349092028 scopus 로고    scopus 로고
    • C-reactive protein improves risk prediction in patients with acute coronary syndromes
    • Schiele F, Meneveau N, Seronde MF, et al. C-reactive protein improves risk prediction in patients with acute coronary syndromes. Eur Heart J 2010;31:290-7.
    • (2010) Eur Heart J , vol.31 , pp. 290-297
    • Schiele, F.1    Meneveau, N.2    Seronde, M.F.3
  • 36
    • 36248975985 scopus 로고    scopus 로고
    • A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: Implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels
    • Tello-Montoliu A, Marín F, Roldán V, et al. A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels. J Intern Med 2007;262:651-8.
    • (2007) J Intern Med , vol.262 , pp. 651-658
    • Tello-Montoliu, A.1    Marín, F.2    Roldán, V.3
  • 37
    • 0034111390 scopus 로고    scopus 로고
    • Predictive value of C-reactive protein and troponin T in patients with unstable angina: A comparative analysis. CAPTURE Investigators. Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial
    • Heeschen C, Hamm CW, Bruemmer J, et al. Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis. CAPTURE Investigators. Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial. J Am Coll Cardiol 2000;35:1535-42.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1535-1542
    • Heeschen, C.1    Hamm, C.W.2    Bruemmer, J.3
  • 38
    • 0034687438 scopus 로고    scopus 로고
    • Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group. Fragmin during instability in coronary artery disease
    • Lindahl B, Toss H, Siegbahn A, et al. Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group. Fragmin during instability in coronary artery disease. N Engl J Med 2000; 343:1139-47.
    • (2000) N Engl J Med , vol.343 , pp. 1139-1147
    • Lindahl, B.1    Toss, H.2    Siegbahn, A.3
  • 39
    • 0031746866 scopus 로고    scopus 로고
    • C-reactive protein is a potent predictor of mortality independently of and in combination with troponin T in acute coronary syndromes: A TIMI 11A substudy. Thrombolysis in myocardial infarction
    • Morrow DA, Rifai N, Antman EM, et al. C-reactive protein is a potent predictor of mortality independently of and in combination with troponin T in acute coronary syndromes: a TIMI 11A substudy. Thrombolysis in myocardial infarction. J Am Coll Cardiol 1998;31:1460-5.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1460-1465
    • Morrow, D.A.1    Rifai, N.2    Antman, E.M.3
  • 40
    • 77649223536 scopus 로고    scopus 로고
    • Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: A meta-analysis of longitudinal studies
    • He LP, Tang XY, Ling WH, et al. Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: a meta-analysis of longitudinal studies. Heart 2010;96:339-46.
    • (2010) Heart , vol.96 , pp. 339-346
    • He, L.P.1    Tang, X.Y.2    Ling, W.H.3
  • 41
    • 84865139743 scopus 로고    scopus 로고
    • Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction
    • Swiatkiewicz I, Kozinski M, Magielski P, et al. Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction. Inflamm Res 2012;61:725-34.
    • (2012) Inflamm Res , vol.61 , pp. 725-734
    • Swiatkiewicz, I.1    Kozinski, M.2    Magielski, P.3
  • 42
    • 84867774445 scopus 로고    scopus 로고
    • Value of C-reactive protein in predicting left ventricular remodelling in patients with a first ST-segment elevation myocardial infarction
    • Swiatkiewicz I, Kozinski M, Magielski P, et al. Value of C-reactive protein in predicting left ventricular remodelling in patients with a first ST-segment elevation myocardial infarction. Mediators Inflamm 2012;2012:250867.
    • (2012) Mediators Inflamm , vol.2012 , pp. 250867
    • Swiatkiewicz, I.1    Kozinski, M.2    Magielski, P.3
  • 43
    • 33644589792 scopus 로고    scopus 로고
    • Early inflammation and risk of long-term development of heart failure and mortality in survivors of acute myocardial infarction predictive role of C-reactive protein
    • Suleiman M, Khatib R, Agmon Y, et al. Early inflammation and risk of long-term development of heart failure and mortality in survivors of acute myocardial infarction predictive role of C-reactive protein. J Am Coll Cardiol 2006;47:962-8.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 962-968
    • Suleiman, M.1    Khatib, R.2    Agmon, Y.3
  • 44
    • 84891504218 scopus 로고    scopus 로고
    • Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association of the European Society of Cardiology. How to use C-reactive protein in acute coronary care
    • Biasucci LM, Koenig W, Mair J, et al. Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association of the European Society of Cardiology. How to use C-reactive protein in acute coronary care. Eur Heart J 2013;34:3687-90.
    • (2013) Eur Heart J , vol.34 , pp. 3687-3690
    • Biasucci, L.M.1    Koenig, W.2    Mair, J.3
  • 45
    • 77955044560 scopus 로고    scopus 로고
    • Evaluating the quality of research into a single prognostic biomarker: A systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease
    • Hemingway H, Philipson P, Chen R, et al. Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease. PLoS Med 2010;7:e1000286.
    • (2010) PLoS Med , vol.7 , pp. e1000286
    • Hemingway, H.1    Philipson, P.2    Chen, R.3
  • 46
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008;359:2195-207.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 47
    • 77954210143 scopus 로고    scopus 로고
    • Cholesterol lowering, cardiovascular diseases, and the rosuvastatin-JUPITER controversy. A critical reappraisal
    • de Lorgeril M, Salen P, Abramson J, et al. Cholesterol lowering, cardiovascular diseases, and the rosuvastatin-JUPITER controversy. A critical reappraisal. Arch Intern Med 2010;170:1032-6.
    • (2010) Arch Intern Med , vol.170 , pp. 1032-1036
    • De Lorgeril, M.1    Salen, P.2    Abramson, J.3
  • 48
    • 84875850647 scopus 로고    scopus 로고
    • Meta-analysis of impact of different types and doses of statins on new-onset diabetes mellitus
    • Navarese EP, Buffon A, Andreotti F, et al. Meta-analysis of impact of different types and doses of statins on new-onset diabetes mellitus. Am J Cardiol 2013;111:1123-30.
    • (2013) Am J Cardiol , vol.111 , pp. 1123-1130
    • Navarese, E.P.1    Buffon, A.2    Andreotti, F.3
  • 49
    • 77649228312 scopus 로고    scopus 로고
    • Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: Justification for the use of statins in prevention: An intervention trial evaluating rosuvastatin (JUPITER)
    • Ridker PM, MacFadyen JG, Fonseca FA, et al. Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER). Circ Cardiovasc Qual Outcomes 2009;2:616-23.
    • (2009) Circ Cardiovasc Qual Outcomes , vol.2 , pp. 616-623
    • Ridker, P.M.1    Macfadyen, J.G.2    Fonseca, F.A.3
  • 50
    • 79851488664 scopus 로고    scopus 로고
    • The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels
    • Choudhry NK, Patrick AR, Glynn RJ, et al. The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels. J Am Coll Cardioll 2011;57:784-91.
    • (2011) J Am Coll Cardioll , vol.57 , pp. 784-791
    • Choudhry, N.K.1    Patrick, A.R.2    Glynn, R.J.3
  • 51
    • 78049304338 scopus 로고    scopus 로고
    • The JUPITER trial: Responding to the critics
    • Ridker PM, Glynn RJ. The JUPITER trial: responding to the critics. Am J Cardiol 2010;106:1351-6.
    • (2010) Am J Cardiol , vol.106 , pp. 1351-1356
    • Ridker, P.M.1    Glynn, R.J.2
  • 52
    • 80053644777 scopus 로고    scopus 로고
    • Interleukin-1b inhibition and the prevention of recurrent cardiovascular events: Rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)
    • Ridker PM, Thuren T, Zalewski A, et al. Interleukin-1b inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS). Am Heart J 2011;162:597-605.
    • (2011) Am Heart J , vol.162 , pp. 597-605
    • Ridker, P.M.1    Thuren, T.2    Zalewski, A.3
  • 53
    • 84880230242 scopus 로고    scopus 로고
    • Association between C reactive protein and coronary heart disease: Mendelian randomisation analysis based on individual participant data
    • C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC); Wensley F, Gao P, Burgess S, et al. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 2011;342:548.
    • (2011) BMJ , vol.342 , pp. 548
    • Wensley, F.1    Gao, P.2    Burgess, S.3
  • 54
    • 67649961412 scopus 로고    scopus 로고
    • Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease
    • Elliott P, Chambers JC, Zhang W, et al. Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA 2009;302:37-48.
    • (2009) JAMA , vol.302 , pp. 37-48
    • Elliott, P.1    Chambers, J.C.2    Zhang, W.3
  • 55
    • 77951753382 scopus 로고    scopus 로고
    • Fibrinogen assays for cardiovascular risk assessment
    • Lowe GD. Fibrinogen assays for cardiovascular risk assessment. Clin Chem 2010;56:693-5.
    • (2010) Clin Chem , vol.56 , pp. 693-695
    • Lowe, G.D.1
  • 56
    • 84859715302 scopus 로고    scopus 로고
    • Fibrinogen as a key regulator of inflammation in disease
    • Davalos D, Akassoglou K. Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol 2012;34:43-62.
    • (2012) Semin Immunopathol , vol.34 , pp. 43-62
    • Davalos, D.1    Akassoglou, K.2
  • 57
    • 84926426742 scopus 로고    scopus 로고
    • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: An individual participant meta-analysis
    • Fibrinogen Studies Collaboration; Danesh J, Lewington S, Thompson SG, et al. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA 2005;294:1799-809.
    • (2005) JAMA , vol.294 , pp. 1799-1809
    • Danesh, J.1    Lewington, S.2    Thompson, S.G.3
  • 58
    • 34848902631 scopus 로고    scopus 로고
    • Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: Individual participant metaanalysis of 154,211 adults in 31 prospective studies: The fibrinogen studies collaboration
    • Fibrinogen Studies Collaboration, Kaptoge S, White IR, Thompson SG, et al. Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant metaanalysis of 154,211 adults in 31 prospective studies: the fibrinogen studies collaboration. Am J Epidemiol 2007;166:867-79.
    • (2007) Am J Epidemiol , vol.166 , pp. 867-879
    • Kaptoge, S.1    White, I.R.2    Thompson, S.G.3
  • 59
    • 38349050019 scopus 로고    scopus 로고
    • The Emerging Risk Factors Collaboration: Analysis of individual data on lipid, inflammatory and other markers in over 1 million participants in 104 prospective studies of cardiovascular diseases
    • Emerging Risk Factors Collaboration, Danesh J, Erqou S, Walker M, et al. The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1. million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol 2007; 22: 839-69.
    • (2007) Eur J Epidemiol , vol.22 , pp. 839-869
    • Danesh, J.1    Erqou, S.2    Walker, M.3
  • 60
    • 84884211438 scopus 로고    scopus 로고
    • Relation of fibrinogen level with cardiovascular events in patients with coronary artery disease
    • Ndrepepa G, Braun S, King L, et al. Relation of fibrinogen level with cardiovascular events in patients with coronary artery disease. Am J Cardiol 2013;111:804-10.
    • (2013) Am J Cardiol , vol.111 , pp. 804-810
    • Ndrepepa, G.1    Braun, S.2    King, L.3
  • 61
    • 84884250513 scopus 로고    scopus 로고
    • Multiethnic metaanalysis of genome-wide association studies in4100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease
    • Sabater-Lleal M, Huang J, Chasman D, et al. Multiethnic metaanalysis of genome-wide association studies in4100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013;128:1310-24.
    • (2013) Circulation , vol.128 , pp. 1310-1324
    • Sabater-Lleal, M.1    Huang, J.2    Chasman, D.3
  • 62
    • 84876673245 scopus 로고    scopus 로고
    • Lp-PLA2-A novel marker of atherosclerosis: To treat or not to treat
    • Tousoulis D, Papageorgiou N, Androulakis E, et al. Lp-PLA2-a novel marker of atherosclerosis: to treat or not to treat? Int J Cardiol 2013;165:213-6.
    • (2013) Int J Cardiol , vol.165 , pp. 213-216
    • Tousoulis, D.1    Papageorgiou, N.2    Androulakis, E.3
  • 63
    • 77951580553 scopus 로고    scopus 로고
    • Lp-PLA(2) and risk of atherosclerotic vascular disease
    • Rosenson RS. Lp-PLA(2) and risk of atherosclerotic vascular disease. Lancet 2010;375:1498-500.
    • (2010) Lancet , vol.375 , pp. 1498-1500
    • Rosenson, R.S.1
  • 64
    • 84878882809 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 (Lp-PLA(2)): A novel and promising biomarker for cardiovascular risks assessment
    • Cai A, Zheng D, Qiu R, et al. Lipoprotein-associated phospholipase A2 (Lp-PLA(2)): a novel and promising biomarker for cardiovascular risks assessment. Dis Markers 2013;34:323-31.
    • (2013) Dis Markers , vol.34 , pp. 323-331
    • Cai, A.1    Zheng, D.2    Qiu, R.3
  • 65
    • 0028968049 scopus 로고
    • Anti-inflammatory properties of a platelet-activating factor acetylhydrolase
    • Tjoelker LW, Wilder C, Eberhardt C, et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 1995;374:549-53.
    • (1995) Nature , vol.374 , pp. 549-553
    • Tjoelker, L.W.1    Wilder, C.2    Eberhardt, C.3
  • 66
    • 0034687446 scopus 로고    scopus 로고
    • Lipoproteinassociated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group
    • Packard CJ, O'Reilly DS, Caslake MJ, et al. Lipoproteinassociated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. N Engl J Med 2000;343:1148-55.
    • (2000) N Engl J Med , vol.343 , pp. 1148-1155
    • Packard, C.J.1    O'Reilly, D.S.2    Caslake, M.J.3
  • 67
    • 28344441841 scopus 로고    scopus 로고
    • Lipoproteinassociated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study
    • Ballantyne CM, Hoogeveen RC, Bang H, et al. Lipoproteinassociated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study. Arch Intern Med 2005;165:2479-84.
    • (2005) Arch Intern Med , vol.165 , pp. 2479-2484
    • Ballantyne, C.M.1    Hoogeveen, R.C.2    Bang, H.3
  • 68
    • 77950021603 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) and risk of cardiovascular disease in older adults: Results from the Cardiovascular Health Study
    • Jenny NS, Solomon C, Cushman M, et al. Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) and risk of cardiovascular disease in older adults: results from the Cardiovascular Health Study. Atherosclerosis 2010;209:528-32.
    • (2010) Atherosclerosis , vol.209 , pp. 528-532
    • Jenny, N.S.1    Solomon, C.2    Cushman, M.3
  • 69
    • 39549091690 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: The Rancho Bernardo Study
    • Daniels LB, Laughlin GA, Sarno MJ, et al. Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study. J Am Coll Cardiol 2008;51:913-9.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 913-919
    • Daniels, L.B.1    Laughlin, G.A.2    Sarno, M.J.3
  • 70
    • 36048962679 scopus 로고    scopus 로고
    • Prognostic utility of lipoprotein-associated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease
    • Sabatine MS, Morrow DA, O'Donoghue M, et al; PEACE Investigators. Prognostic utility of lipoprotein-associated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol 2007;27: 2463-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2463-2469
    • Sabatine, M.S.1    Morrow, D.A.2    O'Donoghue, M.3
  • 71
    • 84865744110 scopus 로고    scopus 로고
    • Clinical utility of lipoprotein-associated phospholipase A2 for cardiovascular disease prediction in a multiethnic cohort of women
    • Cook NR, Paynter NP, Manson JE, et al. Clinical utility of lipoprotein-associated phospholipase A2 for cardiovascular disease prediction in a multiethnic cohort of women. Clin Chem 2012;58:1352-63.
    • (2012) Clin Chem , vol.58 , pp. 1352-1363
    • Cook, N.R.1    Paynter, N.P.2    Manson, J.E.3
  • 72
    • 33846658406 scopus 로고    scopus 로고
    • Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: A systematic review
    • Garza CA, Montori VM, McConnell JP, et al. Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: a systematic review. Mayo Clin Proc 2007;82:159-65.
    • (2007) Mayo Clin Proc , vol.82 , pp. 159-165
    • Garza, C.A.1    Montori, V.M.2    McConnell, J.P.3
  • 73
    • 84862502750 scopus 로고    scopus 로고
    • Lipid-related markers and cardiovascular disease prediction
    • Di Angelantonio E, Gao P, Pennells L, et al. Lipid-related markers and cardiovascular disease prediction. JAMA 2012;307: 2499-506.
    • (2012) JAMA , vol.307 , pp. 2499-2506
    • Di Angelantonio, E.1    Gao, P.2    Pennells, L.3
  • 74
    • 77951605907 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: Collaborative analysis of 32 prospective studies
    • Thompson A, Gao P, Orfei L, et al. Lp-PLA(2) Studies Collaboration. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 2010;375:1536-44.
    • (2010) Lancet , vol.375 , pp. 1536-1544
    • Thompson, A.1    Gao, P.2    Orfei, L.3
  • 75
    • 84860653236 scopus 로고    scopus 로고
    • Relationship of lipoprotein-associated phospholipase A2 mass and activity with incident vascular events among primary prevention patients allocated to placebo or to statin therapy: An analysis from the JUPITER trial
    • Ridker PM, MacFadyen JG, Wolfert RL, et al. Relationship of lipoprotein-associated phospholipase A2 mass and activity with incident vascular events among primary prevention patients allocated to placebo or to statin therapy: an analysis from the JUPITER trial. Clin Chem 2012;58:877-86.
    • (2012) Clin Chem , vol.58 , pp. 877-886
    • Ridker, P.M.1    Macfadyen, J.G.2    Wolfert, R.L.3
  • 76
    • 84860676336 scopus 로고    scopus 로고
    • Lipopssteinsassociated phospholipase A2 measurements: Mass, activity, but little productivity
    • Stein EA. Lipopssteinsassociated phospholipase A2 measurements: mass, activity, but little productivity. Clin Chem 2012;58: 814-7.
    • (2012) Clin Chem , vol.58 , pp. 814-817
    • Stein, E.A.1
  • 77
    • 77953230836 scopus 로고    scopus 로고
    • PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry
    • Casas JP, Ninio E, Panayiotou A, et al. PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry. Circulation 2010;121:2284-93.
    • (2010) Circulation , vol.121 , pp. 2284-2293
    • Casas, J.P.1    Ninio, E.2    Panayiotou, A.3
  • 78
    • 84856169719 scopus 로고    scopus 로고
    • Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: Meta-analysis of genomewide association studies from five community-based studies
    • Grallert H, Dupuis J, Bis JC, et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genomewide association studies from five community-based studies. Eur Heart J 2012;33:238-51.
    • (2012) Eur Heart J , vol.33 , pp. 238-251
    • Grallert, H.1    Dupuis, J.2    Bis, J.C.3
  • 79
    • 77956306449 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 activity and mass in relation to vascular disease and nonvascular mortality
    • Heart Protection Study Collaborative Group. Lipoprotein-associated phospholipase A2 activity and mass in relation to vascular disease and nonvascular mortality. J Intern Med 2010;268: 348-58.
    • (2010) J Intern Med , vol.268 , pp. 348-358
  • 80
    • 84891705653 scopus 로고    scopus 로고
    • Changes in lipoproteinassociated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: Results from the long-term intervention with pravastatin in ischemic disease study
    • White HD, Simes J, Stewart RA, et al. Changes in lipoproteinassociated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: results from the long-term intervention with pravastatin in ischemic disease study. J Am Heart Assoc 2013;2:e000360.
    • (2013) J Am Heart Assoc , vol.2 , pp. e000360
    • White, H.D.1    Simes, J.2    Stewart, R.A.3
  • 81
    • 79951554458 scopus 로고    scopus 로고
    • Simvastatin reduces lipoproteinassociated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogenactivated protein kinase pathway
    • Song JX, Ren JY, Chen H. Simvastatin reduces lipoproteinassociated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogenactivated protein kinase pathway. J Cardiovasc Pharmacol 2011; 57:213-22.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 213-222
    • Song, J.X.1    Ren, J.Y.2    Chen, H.3
  • 82
    • 84891142213 scopus 로고    scopus 로고
    • Varespladib and cardiovascular events in patients with an acute coronary syndrome: The VISTA-16 randomized clinical trial
    • Nicholls SJ, Kastelein JJ, Schwartz GG, et al. Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. JAMA 2014;311: 252-62.
    • (2014) JAMA , vol.311 , pp. 252-262
    • Nicholls, S.J.1    Kastelein, J.J.2    Schwartz, G.G.3
  • 83
    • 84891812420 scopus 로고    scopus 로고
    • Effect of treatment for 12 weeks with rilapladib, a lipoprotein-associated phospholipase A2 inhibitor, on arterial inflammation as assessed with 18F-fluorodeoxyglucose-positron emission tomography imaging
    • Tawakol A, Singh P, Rudd JH, et al. Effect of treatment for 12 weeks with rilapladib, a lipoprotein-associated phospholipase A2 inhibitor, on arterial inflammation as assessed with 18F-fluorodeoxyglucose-positron emission tomography imaging. J Am Coll Cardiol 2014;63:86-8.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 86-88
    • Tawakol, A.1    Singh, P.2    Rudd, J.H.3
  • 84
    • 77955585234 scopus 로고    scopus 로고
    • Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque by Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease
    • White H, Held C, Stewart R, et al. Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease. Am Heart J 2010;160:655-61.
    • (2010) Am Heart J , vol.160 , pp. 655-661
    • White, H.1    Held, C.2    Stewart, R.3
  • 85
    • 80053647826 scopus 로고    scopus 로고
    • Study design and rationale for the stabilization of plaques using darapladibthrombolysis in myocardial infarction (SOLID-TIMI 52) trial in patients after an acute coronary syndrome
    • O'Donoghue ML, Braunwald E, White HD, et al. Study design and rationale for the stabilization of plaques using darapladibthrombolysis in myocardial infarction (SOLID-TIMI 52) trial in patients after an acute coronary syndrome. Am Heart J 2011;162: 613-619.
    • (2011) Am Heart J , vol.162 , pp. 613-619
    • O'Donoghue, M.L.1    Braunwald, E.2    White, H.D.3
  • 86
    • 84899718423 scopus 로고    scopus 로고
    • Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease
    • in press (last accessed March 2014)
    • The STABILITY Investigators. Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease. N Engl J Med 2014; in press. http://www.gsk.com/media/press-releases/2013/gsk-announces- top-line-results-from-pivotal-phase-iii-study-of-d.html (last accessed March 2014).
    • (2014) N Engl J Med
  • 88
    • 84860144206 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists' guidelines for management of dyslipidemia and prevention of atherosclerosis
    • Jellinger PS, Smith DA, Mehta AE, et al. American Association of Clinical Endocrinologists' guidelines for management of dyslipidemia and prevention of atherosclerosis. Endocr Pract 2012; 181: 1-78.
    • (2012) Endocr Pract , vol.181 , pp. 1-78
    • Jellinger, P.S.1    Smith, D.A.2    Mehta, A.E.3
  • 89
    • 43849102348 scopus 로고    scopus 로고
    • Myeloperoxidase: A new biomarker of inflammation in ischemic heart disease and acute coronary syndromes
    • Loria V, Dato I, Graziani F, et al. Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromes. Mediators Inflamm 2008;2008:135625.
    • (2008) Mediators Inflamm , vol.2008 , pp. 135625
    • Loria, V.1    Dato, I.2    Graziani, F.3
  • 90
    • 81255214697 scopus 로고    scopus 로고
    • Myeloperoxidase in the diagnosis of acute coronary syndromes: The importance of spectrum
    • Peacock WF, Nagurney J, Birkhahn R, et al. Myeloperoxidase in the diagnosis of acute coronary syndromes: the importance of spectrum. Am Heart J 2011;162:893-9.
    • (2011) Am Heart J , vol.162 , pp. 893-899
    • Peacock, W.F.1    Nagurney, J.2    Birkhahn, R.3
  • 91
    • 30544444120 scopus 로고    scopus 로고
    • Myeloperoxidasemediated oxidation of high-density lipoproteins: Fingerprints of newly recognized potential proatherogenic lipoproteins
    • Malle E, Marsche G, Panzenboeck U, et al. Myeloperoxidasemediated oxidation of high-density lipoproteins: fingerprints of newly recognized potential proatherogenic lipoproteins. Arch Biochem Biophys 2006;445:245-55.
    • (2006) Arch Biochem Biophys , vol.445 , pp. 245-255
    • Malle, E.1    Marsche, G.2    Panzenboeck, U.3
  • 92
    • 85006532217 scopus 로고    scopus 로고
    • The role of matrix metalloproteinase-3 in the development of atherosclerosis and cardiovascular events
    • Krintus M, Kuligowska M, Sypniewska G. The role of matrix metalloproteinase-3 in the development of atherosclerosis and cardiovascular events. eJIFCC 2006;17:1.
    • (2006) EJIFCC , vol.17 , pp. 1
    • Krintus, M.1    Kuligowska, M.2    Sypniewska, G.3
  • 93
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colonystimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • Sugiyama S, Okada Y, Sukhova GK, et al. Macrophage myeloperoxidase regulation by granulocyte macrophage colonystimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 2001;158:879-91.
    • (2001) Am J Pathol , vol.158 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3
  • 94
    • 78650985715 scopus 로고    scopus 로고
    • Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease
    • Tang WH, Wu Y, Nicholls SJ, et al. Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease. Clin Chem 2011;57:33-9.
    • (2011) Clin Chem , vol.57 , pp. 33-39
    • Tang, W.H.1    Wu, Y.2    Nicholls, S.J.3
  • 95
    • 78650686947 scopus 로고    scopus 로고
    • High levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: A clinicopathological study
    • Ferrante G, Nakano M, Prati F, et al. High levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: a clinicopathological study. Circulation 2010;122:2505-13.
    • (2010) Circulation , vol.122 , pp. 2505-2513
    • Ferrante, G.1    Nakano, M.2    Prati, F.3
  • 96
    • 82755195303 scopus 로고    scopus 로고
    • Risk prediction with serial myeloperoxidase monitoring in patients with acute chest pain
    • Nicholls SJ, Tang WH, Brennan D, et al. Risk prediction with serial myeloperoxidase monitoring in patients with acute chest pain. Clin Chem 2011;57:1762-70.
    • (2011) Clin Chem , vol.57 , pp. 1762-1770
    • Nicholls, S.J.1    Tang, W.H.2    Brennan, D.3
  • 97
    • 0035824162 scopus 로고    scopus 로고
    • Association between myeloperoxidase levels and risk of coronary artery disease
    • Zhang R, Brennan ML, Fu X, et al. Association between myeloperoxidase levels and risk of coronary artery disease. JAMA 2001;286:2136-42.
    • (2001) JAMA , vol.286 , pp. 2136-2142
    • Zhang, R.1    Brennan, M.L.2    Fu, X.3
  • 98
    • 34347225913 scopus 로고    scopus 로고
    • Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: The EPIC-Norfolk Prospective Population Study
    • Meuwese MC, Stroes ES, Hazen SL, et al. Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 2007;50:159-65.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 159-165
    • Meuwese, M.C.1    Stroes, E.S.2    Hazen, S.L.3
  • 99
    • 77749310803 scopus 로고    scopus 로고
    • Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography
    • Heslop CL1, Frohlich JJ, Hill JS. Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography. J Am Coll Cardiol 2010;55:1102-9.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1102-1109
    • Heslop, C.L.1    Frohlich, J.J.2    Hill, J.S.3
  • 100
    • 70249144887 scopus 로고    scopus 로고
    • Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease events
    • Wong ND, Gransar H, Narula J, et al. Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease events. JACC Cardiovasc Imaging 2009;2:1093-9.
    • (2009) JACC Cardiovasc Imaging , vol.2 , pp. 1093-1099
    • Wong, N.D.1    Gransar, H.2    Narula, J.3
  • 101
    • 0141727730 scopus 로고    scopus 로고
    • Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
    • Baldus S, Heeschen C, Meinertz T, et al; CAPTURE Investigators. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation 2003;108:1440-5.
    • (2003) Circulation , vol.108 , pp. 1440-1445
    • Baldus, S.1    Heeschen, C.2    Meinertz, T.3
  • 102
    • 58149215829 scopus 로고    scopus 로고
    • Assessment of the multiple-biomarker approach for diagnosis of myocardial infarction in patients presenting with symptoms suggestive of acute coronary syndrome
    • Apple FS, Smith SW, Pearce LA, et al. Assessment of the multiple-biomarker approach for diagnosis of myocardial infarction in patients presenting with symptoms suggestive of acute coronary syndrome. Clin Chem 2009;55:93-100.
    • (2009) Clin Chem , vol.55 , pp. 93-100
    • Apple, F.S.1    Smith, S.W.2    Pearce, L.A.3
  • 103
    • 70449368524 scopus 로고    scopus 로고
    • The use of biochip cardiac array technology for early diagnosis of acute coronary syndromes
    • Sypniewska G, Sawicki M, Krintus M, et al. The use of biochip cardiac array technology for early diagnosis of acute coronary syndromes. J Med Biochem 2009;28:293-9.
    • (2009) J Med Biochem , vol.28 , pp. 293-299
    • Sypniewska, G.1    Sawicki, M.2    Krintus, M.3
  • 104
    • 79956133197 scopus 로고    scopus 로고
    • Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin i concentrations
    • Apple FS, Smith SW, Pearce LA, et al. Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin I concentrations. Clin Chem 2011;57:603-8.
    • (2011) Clin Chem , vol.57 , pp. 603-608
    • Apple, F.S.1    Smith, S.W.2    Pearce, L.A.3
  • 105
    • 79955613614 scopus 로고    scopus 로고
    • Diagnostic efficacy of myeloperoxidase for the detection of acute coronary syndromes
    • Sawicki M, Sypniewska G, Kozinski M, et al. Diagnostic efficacy of myeloperoxidase for the detection of acute coronary syndromes. Eur J Clin Invest 2011;41:667-71.
    • (2011) Eur J Clin Invest , vol.41 , pp. 667-671
    • Sawicki, M.1    Sypniewska, G.2    Kozinski, M.3
  • 106
    • 44849096170 scopus 로고    scopus 로고
    • Effect of collection tube type and preanalytical handling on myeloperoxidase concentrations
    • Shih J, Datwyler SA, Hsu SC, et al. Effect of collection tube type and preanalytical handling on myeloperoxidase concentrations. Clin Chem 2008;54:1076-9.
    • (2008) Clin Chem , vol.54 , pp. 1076-1079
    • Shih, J.1    Datwyler, S.A.2    Hsu, S.C.3
  • 107
    • 84902140590 scopus 로고    scopus 로고
    • The role of myeloperoxidase (MPO) for prognostic evaluation in sensitive cardiac troponin i negative chest pain patients in the emergency department
    • Searle J, Shih J, Muller R, et al. The role of myeloperoxidase (MPO) for prognostic evaluation in sensitive cardiac troponin I negative chest pain patients in the emergency department. Eur Heart J Acute Cardiovasc Care 2013;2:203-10.
    • (2013) Eur Heart J Acute Cardiovasc Care , vol.2 , pp. 203-210
    • Searle, J.1    Shih, J.2    Muller, R.3
  • 108
    • 79952849795 scopus 로고    scopus 로고
    • Assessment of multiple cardiac biomarkers in non-ST-segment elevation acute coronary syndromes: Observations from the MERLIN-TIMI 36 trial
    • Scirica BM, Sabatine MS, Jarolim P, et al. Assessment of multiple cardiac biomarkers in non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 trial. Eur Heart J 2011;32:697-705.
    • (2011) Eur Heart J , vol.32 , pp. 697-705
    • Scirica, B.M.1    Sabatine, M.S.2    Jarolim, P.3
  • 109
    • 79961089728 scopus 로고    scopus 로고
    • Diagnostic performance of highsensitivity troponin T, myeloperoxidase, and pregnancy-associated plasma protein A assays for triage of patients with acute myocardial infarction
    • Khan DA, Sharif MS, Khan FA. Diagnostic performance of highsensitivity troponin T, myeloperoxidase, and pregnancy-associated plasma protein A assays for triage of patients with acute myocardial infarction. Korean J Lab Med 2011;31:172-8.
    • (2011) Korean J Lab Med , vol.31 , pp. 172-178
    • Khan, D.A.1    Sharif, M.S.2    Khan, F.A.3
  • 110
    • 84883809336 scopus 로고    scopus 로고
    • The multiple facets of the TGF-b family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1
    • Unsicker K, Spittau B, Krieglstein K, et al. The multiple facets of the TGF-b family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1. Cytokine Growth Factor Rev 2013;24:373-84.
    • (2013) Cytokine Growth Factor Rev , vol.24 , pp. 373-384
    • Unsicker, K.1    Spittau, B.2    Krieglstein, K.3
  • 111
    • 84881247815 scopus 로고    scopus 로고
    • Growth differentiation factor 15 deficiency inhibits atherosclerosis progression by regulating IL-6-dependent inflammatory response to vascular injury
    • Bonaterra GA, Zugel S, Thogersen J, et al. Growth differentiation factor 15 deficiency inhibits atherosclerosis progression by regulating IL-6-dependent inflammatory response to vascular injury. J Am Heart Assoc 2012;1:e002550.
    • (2012) J Am Heart Assoc , vol.1 , pp. e002550
    • Bonaterra, G.A.1    Zugel, S.2    Thogersen, J.3
  • 112
    • 84863034556 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease
    • Breit SN, Carrero JJ, Wang-Wei Tsai V, et al. Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease. Nephrol Dial Transplant 2012;27:70-5.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 70-75
    • Breit, S.N.1    Carrero, J.J.2    Wang-Wei Tsai, V.3
  • 113
    • 67650671369 scopus 로고    scopus 로고
    • Growth differentiation factor-15 in heart failure
    • Kempf T, Wollert KC. Growth differentiation factor-15 in heart failure. Heart Fail Clin 2009;5:537-47.
    • (2009) Heart Fail Clin , vol.5 , pp. 537-547
    • Kempf, T.1    Wollert, K.C.2
  • 114
    • 46749134833 scopus 로고    scopus 로고
    • Influence of postprandial triglyceride-rich lipoproteins on lipid mediated gene expression in smooth muscle cells of the human coronary artery
    • Bermudez B, Lopez S, Pacheco YM, et al. Influence of postprandial triglyceride-rich lipoproteins on lipid mediated gene expression in smooth muscle cells of the human coronary artery. Cardiovasc Res 2008;79:294-303.
    • (2008) Cardiovasc Res , vol.79 , pp. 294-303
    • Bermudez, B.1    Lopez, S.2    Pacheco, Y.M.3
  • 115
    • 79955703474 scopus 로고    scopus 로고
    • GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice
    • Kempf T, Zarbock A, Widera C, et al. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat Med 2011;7:581-8.
    • (2011) Nat Med , vol.7 , pp. 581-588
    • Kempf, T.1    Zarbock, A.2    Widera, C.3
  • 116
    • 84868520076 scopus 로고    scopus 로고
    • Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE(-/-) mice from the development of atherosclerosis
    • Johnen H, Kuffner T, Brown DA, et al. Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE(-/-) mice from the development of atherosclerosis. Cardiovasc Pathol 2012;21:499-505.
    • (2012) Cardiovasc Pathol , vol.21 , pp. 499-505
    • Johnen, H.1    Kuffner, T.2    Brown, D.A.3
  • 117
    • 84856030536 scopus 로고    scopus 로고
    • Relations of growthdifferentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects
    • Eggers KM, Lind L, Sundström J, et al. Relations of growthdifferentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects. Scand J Clin Lab Invest 2012;72:45-51.
    • (2012) Scand J Clin Lab Invest , vol.72 , pp. 45-51
    • Eggers, K.M.1    Lind, L.2    Sundström, J.3
  • 118
    • 84868117019 scopus 로고    scopus 로고
    • Clinical and genetic correlates of growth differentiation factor-15 in the community
    • Ho JE, Mahajan A, Chen MH, et al. Clinical and genetic correlates of growth differentiation factor-15 in the community. Clin Chem 2012; 58:1582-91.
    • (2012) Clin Chem , vol.58 , pp. 1582-1591
    • Ho, J.E.1    Mahajan, A.2    Chen, M.H.3
  • 119
    • 78249249270 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 (MIC-1/GDF15): A new marker of all-cause mortality
    • Wiklund FE, Bennet AM, Magnusson PKE, et al. Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality. Aging Cell 2010;9:1057-64.
    • (2010) Aging Cell , vol.9 , pp. 1057-1064
    • Wiklund, F.E.1    Bennet, A.M.2    Magnusson, P.K.E.3
  • 120
    • 78650367767 scopus 로고    scopus 로고
    • Multiple marker approach to risk stratification in patients with stable coronary artery disease
    • Schnabel RB, Schulz A, Messow CM, et al. Multiple marker approach to risk stratification in patients with stable coronary artery disease. Eur Heart J 2010;31:3024-31.
    • (2010) Eur Heart J , vol.31 , pp. 3024-3031
    • Schnabel, R.B.1    Schulz, A.2    Messow, C.M.3
  • 121
    • 77952536044 scopus 로고    scopus 로고
    • Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndrome
    • Eggers KM, Kempf T, Lagerqvist B, et al. Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndrome. Circ Cardiovasc Genet 2010;3:88-96.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 88-96
    • Eggers, K.M.1    Kempf, T.2    Lagerqvist, B.3
  • 122
    • 84881474669 scopus 로고    scopus 로고
    • Utility of 14 novel biomarkers in patients with acute chest pain and undetectable levels of conventional cardiac troponin
    • Meune C, Balmelli C, Twerenbold R, et al. Utility of 14 novel biomarkers in patients with acute chest pain and undetectable levels of conventional cardiac troponin. Int J Cardiol 2013;167: 1164-9.
    • (2013) Int J Cardiol , vol.167 , pp. 1164-1169
    • Meune, C.1    Balmelli, C.2    Twerenbold, R.3
  • 123
    • 84891536389 scopus 로고    scopus 로고
    • Incremental prognostic value of biomarkers beyond the GRACE score and high-sensitivity cardiac troponin T in non-ST-elevation acute coronary syndrome
    • Widera C, Pencina MJ, Bobadilla M, et al. Incremental prognostic value of biomarkers beyond the GRACE score and high-sensitivity cardiac troponin T in non-ST-elevation acute coronary syndrome. Clin Chem 2013;59:1497-1505.
    • (2013) Clin Chem , vol.59 , pp. 1497-1505
    • Widera, C.1    Pencina, M.J.2    Bobadilla, M.3
  • 124
    • 84887113261 scopus 로고    scopus 로고
    • The story of growth differentiation factor-15: Another piece of the puzzle
    • Lindahl B. The story of growth differentiation factor-15: another piece of the puzzle. Clin Chem 2013;59:1550-1552.
    • (2013) Clin Chem , vol.59 , pp. 1550-1552
    • Lindahl, B.1
  • 125
    • 33847284450 scopus 로고    scopus 로고
    • Prognostic value of growthdifferentiation factor-15 in patients with non-ST-elevation acute coronary syndrome
    • Wollert KC, Kempf T, Peter T, et al. Prognostic value of growthdifferentiation factor-15 in patients with non-ST-elevation acute coronary syndrome. Circulation 2007;115:962-71.
    • (2007) Circulation , vol.115 , pp. 962-971
    • Wollert, K.C.1    Kempf, T.2    Peter, T.3
  • 126
    • 70349652501 scopus 로고    scopus 로고
    • Reference change values and determinants of variability of NT-proANP and GDF15 in stable chronic heart failure
    • Frankenstein L1, Remppis A, Frankenstein J, et al. Reference change values and determinants of variability of NT-proANP and GDF15 in stable chronic heart failure. Basic Res Cardiol 2009; 104:731-8.
    • (2009) Basic Res Cardiol , vol.104 , pp. 731-738
    • Frankenstein, L.1    Remppis, A.2    Frankenstein, J.3
  • 127
    • 77949330682 scopus 로고    scopus 로고
    • The report card on growth differentiation factor 15: Consistent marks but not yet ready for promotion
    • Rohatgi A, de Lemos JA. The report card on growth differentiation factor 15: consistent marks but not yet ready for promotion. Circ Cardiovasc Genet 2009;2:209-11.
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 209-211
    • Rohatgi, A.1    De Lemos, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.