GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

Nature Medicine

Volumn 17, Issue 5, 2011, Pages 581-588

  Kempf, Tibor ^a   Zarbock, Alexander ^b   Widera, Christian ^a   Butz, Stefan ^b   Stadtmann, Anika ^b   Rossaint, Jan ^b   Bolomini Vittori, Matteo ^c   Korf Klingebiel, Mortimer ^a   Napp, L Christian ^a   Hansen, Birte ^a   Kanwischer, Anna ^a   Bavendiek, Udo ^a   Beutel, Gernot ^a   Hapke, Martin ^a   Sauer, Martin G ^a   Laudanna, Carlo ^c   Hogg, Nancy ^d   Vestweber, Dietmar ^b   Wollert, Kai C ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF VERONA   (Italy)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 INTEGRIN; GROWTH DIFFERENTIATION FACTOR 15; PROTEIN CDC42; RAP1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM; HEART INFARCTION; HEART RUPTURE; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MALE; MICROSCOPY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; ANTIGENS, CD18; CDC42 GTP-BINDING PROTEIN; CELL ADHESION; CELL MOVEMENT; GROWTH DIFFERENTIATION FACTOR 15; INTEGRINS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; MYOCARDIAL INFARCTION; NEUTROPHILS; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

MUS;

EID: 79955703474     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2354     Document Type: Article

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