메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages 1-8

Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD)

Author keywords

Autophagy; Chaihu; Chinese medicine; Qi; saikosaponin

Indexed keywords

BUPLEURUM ROOT EXTRACT; SAIKOSAPONIN; STRESS HORMONE;

EID: 84907396413     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-9-21     Document Type: Review
Times cited : (41)

References (108)
  • 1
    • 85067759244 scopus 로고    scopus 로고
    • The overview of xiao yao powder in clinical practice
    • Huang Z. The overview of xiao yao powder in clinical practice. J Guangxi Tradit Chin Med Univ 2009, 12:76-78.
    • (2009) J Guangxi Tradit Chin Med Univ , vol.12 , pp. 76-78
    • Huang, Z.1
  • 2
    • 85067746731 scopus 로고    scopus 로고
    • The clinical application of da chaihu decoction
    • Wei DY, Wang GY. The clinical application of da chaihu decoction. Mod J Integr Tradit Chin Wes Med 2013, 22:1476-1478.
    • (2013) Mod J Integr Tradit Chin Wes Med , vol.22 , pp. 1476-1478
    • Wei, D.Y.1    Wang, G.Y.2
  • 3
    • 85067745724 scopus 로고    scopus 로고
    • Treated chronic cholecystitis alternating chills and fevers syndrome with xiao chai hu decoction in 59 cases
    • Liu CL. Treated chronic cholecystitis alternating chills and fevers syndrome with xiao chai hu decoction in 59 cases. Guangming J Chin Med 2012, 27:63.
    • (2012) Guangming J Chin Med , vol.27 , pp. 63
    • Liu, C.L.1
  • 4
    • 85067777505 scopus 로고    scopus 로고
    • Effects of CHSGS on behavior and hippocampal monoamine neurotransmitter in Alzheimer's disease rats with liver-qi
    • Xuan X, Rong ZB, Liu C, Li YH, Duan LH, Li LJ, Wu ZZ. Effects of CHSGS on behavior and hippocampal monoamine neurotransmitter in Alzheimer's disease rats with liver-qi. Shenzhen J Integ Tradit Chin Wes Med 2013, 23:129-134.
    • (2013) Shenzhen J Integ Tradit Chin Wes Med , vol.23 , pp. 129-134
    • Xuan, X.1    Rong, Z.B.2    Liu, C.3    Li, Y.H.4    Duan, L.H.5    Li, L.J.6    Wu, Z.Z.7
  • 6
    • 84907413289 scopus 로고
    • The comparison of the pharmacological effect of nan Chaihu and bei Chaihu: the pilot study of anti-pyretic and hepatoprotective effect
    • Li TL, Du XW. The comparison of the pharmacological effect of nan Chaihu and bei Chaihu: the pilot study of anti-pyretic and hepatoprotective effect. Acta Chin Med Pharmacol 1992, 3:34-37.
    • (1992) Acta Chin Med Pharmacol , vol.3 , pp. 34-37
    • Li, T.L.1    Du, X.W.2
  • 8
    • 0029166186 scopus 로고
    • The immunomodulatory effect of saikosaponin derivatives and the root extract of Bupleurum kaoi in mice
    • Yen MH, Lin CC, Yen CM. The immunomodulatory effect of saikosaponin derivatives and the root extract of Bupleurum kaoi in mice. Phytother Res 1995, 9:351-358.
    • (1995) Phytother Res , vol.9 , pp. 351-358
    • Yen, M.H.1    Lin, C.C.2    Yen, C.M.3
  • 9
    • 33745171392 scopus 로고    scopus 로고
    • Antiviral effects of saikosaponins on human coronavirus 229E in vitro
    • 16789928
    • Cheng PW, Ng LT, Chiang LC, Lin CC. Antiviral effects of saikosaponins on human coronavirus 229E in vitro. Clin Exp Pharmacol Physiol 2006, 33:612-616. 10.1111/j.1440-1681.2006.04415.x, 16789928.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 612-616
    • Cheng, P.W.1    Ng, L.T.2    Chiang, L.C.3    Lin, C.C.4
  • 10
    • 77951902616 scopus 로고    scopus 로고
    • Antinociceptive and antipyretic properties of the pharmaceutical herbal preparation, Radix bupleuri in rats
    • Usman MSI, Africa LJ, Akuodor GC, Ugwu TC, Osunkwo UA. Antinociceptive and antipyretic properties of the pharmaceutical herbal preparation, Radix bupleuri in rats. J Medic Plants Res 2010, 4:659-663.
    • (2010) J Medic Plants Res , vol.4 , pp. 659-663
    • Usman, M.S.I.1    Africa, L.J.2    Akuodor, G.C.3    Ugwu, T.C.4    Osunkwo, U.A.5
  • 11
  • 12
    • 0016624974 scopus 로고
    • Saponins isolated from Bupleurum falcatum L.; components of saikosaponin b
    • Shimaoka A, Seo S, Minato H. Saponins isolated from Bupleurum falcatum L.; components of saikosaponin b. J Chem Soc Perkin 1 1975, 20:2043-2048.
    • (1975) J Chem Soc Perkin 1 , vol.20 , pp. 2043-2048
    • Shimaoka, A.1    Seo, S.2    Minato, H.3
  • 13
    • 84969307016 scopus 로고    scopus 로고
    • Research development on hepatoprotective effect and hepatotoxicity based on bupleurum saikosaponin components
    • Huang W, Zhao Y, Sun R. Research development on hepatoprotective effect and hepatotoxicity based on bupleurum saikosaponin components. Chin J Pharmacovigilance 2011, 8:38-40.
    • (2011) Chin J Pharmacovigilance , vol.8 , pp. 38-40
    • Huang, W.1    Zhao, Y.2    Sun, R.3
  • 14
    • 52049124548 scopus 로고    scopus 로고
    • Effect of Bupleuri Radix extracts on the toxicity of 5-fluorouracil in HepG2 hepatoma cells and normal human lymphocytes
    • 18834353
    • Kang SJ, Lee YJ, Kim BM, Kim YJ, Woo HD, Jeon HK, Chung HW. Effect of Bupleuri Radix extracts on the toxicity of 5-fluorouracil in HepG2 hepatoma cells and normal human lymphocytes. Basic Clin Pharmacol Toxicol 2008, 103:305-313. 10.1111/j.1742-7843.2008.00280.x, 18834353.
    • (2008) Basic Clin Pharmacol Toxicol , vol.103 , pp. 305-313
    • Kang, S.J.1    Lee, Y.J.2    Kim, B.M.3    Kim, Y.J.4    Woo, H.D.5    Jeon, H.K.6    Chung, H.W.7
  • 17
    • 77954860465 scopus 로고    scopus 로고
    • The clinical application and modern research progress of CHSGS
    • Zhang HW, Zhou ZM. The clinical application and modern research progress of CHSGS. Lishizhen medicine and materia medica Res 2007, 18:1234-1236.
    • (2007) Lishizhen medicine and materia medica Res , vol.18 , pp. 1234-1236
    • Zhang, H.W.1    Zhou, Z.M.2
  • 19
    • 33746570817 scopus 로고    scopus 로고
    • Progress in research on antitumor activity of saikosaponin and its mechanism
    • Wang YL, He SX, Luo JY. Progress in research on antitumor activity of saikosaponin and its mechanism. Zhong Xi Yi Jie He Xue Bao 2006, 4:98-100.
    • (2006) Zhong Xi Yi Jie He Xue Bao , vol.4 , pp. 98-100
    • Wang, Y.L.1    He, S.X.2    Luo, J.Y.3
  • 20
    • 77954163114 scopus 로고    scopus 로고
    • Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS
    • 20512808
    • Yang YY, Tang YZ, Fan CL, Luo HT, Guo PR, Chen JX. Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS. J Sep Sci 2010, 33:1933-1945. 10.1002/jssc.201000100, 20512808.
    • (2010) J Sep Sci , vol.33 , pp. 1933-1945
    • Yang, Y.Y.1    Tang, Y.Z.2    Fan, C.L.3    Luo, H.T.4    Guo, P.R.5    Chen, J.X.6
  • 21
    • 3442897965 scopus 로고    scopus 로고
    • Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies
    • 14709901
    • Zhu SH, Shimokawa S, Tanaka H, Shoyama Y. Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies. Biol Pharm Bull 2004, 27:66-71. 10.1248/bpb.27.66, 14709901.
    • (2004) Biol Pharm Bull , vol.27 , pp. 66-71
    • Zhu, S.H.1    Shimokawa, S.2    Tanaka, H.3    Shoyama, Y.4
  • 22
    • 9644290789 scopus 로고    scopus 로고
    • Saikosaponin-a induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells
    • 12943168
    • Chen JC, Chang NW, Chung JG, Chen KC. Saikosaponin-a induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells. Am J Chin Med 2003, 31:363-377. 10.1142/S0192415X03001065, 12943168.
    • (2003) Am J Chin Med , vol.31 , pp. 363-377
    • Chen, J.C.1    Chang, N.W.2    Chung, J.G.3    Chen, K.C.4
  • 23
    • 79951581748 scopus 로고    scopus 로고
    • Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines
    • 21107704
    • Kim BM, Hong SH. Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis 2011, 16:184-197. 10.1007/s10495-010-0557-x, 21107704.
    • (2011) Apoptosis , vol.16 , pp. 184-197
    • Kim, B.M.1    Hong, S.H.2
  • 24
    • 67349212587 scopus 로고    scopus 로고
    • Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis
    • 19375524
    • Sun Y, Cai TT, Zhou XB, Xu Q. Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. Int Immunopharmacol 2009, 9:978-983. 10.1016/j.intimp.2009.04.006, 19375524.
    • (2009) Int Immunopharmacol , vol.9 , pp. 978-983
    • Sun, Y.1    Cai, T.T.2    Zhou, X.B.3    Xu, Q.4
  • 25
    • 0034806214 scopus 로고    scopus 로고
    • Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells
    • 11444823
    • Wu WS, Hsu HY. Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells. Biochem Biophys Res Commun 2001, 285:183-187. 10.1006/bbrc.2001.5152, 11444823.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 183-187
    • Wu, W.S.1    Hsu, H.Y.2
  • 26
    • 46749151009 scopus 로고    scopus 로고
    • Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats
    • 18598162
    • Wu SJ, Lin YH, Chu CC, Tsai YH, Chao JC. Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats. J Med Food 2008, 11:224-229. 10.1089/jmf.2007.555, 18598162.
    • (2008) J Med Food , vol.11 , pp. 224-229
    • Wu, S.J.1    Lin, Y.H.2    Chu, C.C.3    Tsai, Y.H.4    Chao, J.C.5
  • 27
    • 9644279912 scopus 로고    scopus 로고
    • Saikosaponin C induces endothelial cells growth, migration and capillary tube formation
    • 15581913
    • Shyu KG, Tsai SC, Wang BW, Liu YC, Lee CC. Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. Life Sci 2004, 76:813-826. 10.1016/j.lfs.2004.10.003, 15581913.
    • (2004) Life Sci , vol.76 , pp. 813-826
    • Shyu, K.G.1    Tsai, S.C.2    Wang, B.W.3    Liu, Y.C.4    Lee, C.C.5
  • 28
    • 0141705407 scopus 로고    scopus 로고
    • Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species
    • Chiang LC, Ng LT, Liu LT, Shieh DE, Lin CC. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med 2003, 69:705-709.
    • (2003) Planta Med , vol.69 , pp. 705-709
    • Chiang, L.C.1    Ng, L.T.2    Liu, L.T.3    Shieh, D.E.4    Lin, C.C.5
  • 29
    • 84876545441 scopus 로고    scopus 로고
    • Saikosaponin-d enhances the anticancer potency of TNF-alpha via overcoming its undesirable response of activating NF-Kappa B signalling in cancer cells
    • 3610377, 23573150
    • Wong VK, Zhang MM, Zhou H, Lam KY, Chan PL, Law CK, Yue PY, Liu L. Saikosaponin-d enhances the anticancer potency of TNF-alpha via overcoming its undesirable response of activating NF-Kappa B signalling in cancer cells. Evid Based Complement Alternat Med 2013, 2013:745295. 3610377, 23573150.
    • (2013) Evid Based Complement Alternat Med , vol.2013 , pp. 745295
    • Wong, V.K.1    Zhang, M.M.2    Zhou, H.3    Lam, K.Y.4    Chan, P.L.5    Law, C.K.6    Yue, P.Y.7    Liu, L.8
  • 30
    • 0021804787 scopus 로고
    • Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone
    • 2864416
    • Abe H, Orita M, Konishi H, Arichi S, Odashima S. Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone. J Pharm Pharmacol 1985, 37:555-559. 10.1111/j.2042-7158.1985.tb03066.x, 2864416.
    • (1985) J Pharm Pharmacol , vol.37 , pp. 555-559
    • Abe, H.1    Orita, M.2    Konishi, H.3    Arichi, S.4    Odashima, S.5
  • 31
    • 3042541878 scopus 로고    scopus 로고
    • The proliferative inhibition and apoptotic mechanism of saikosaponin d in human non-small cell lung cancer A549 cells
    • 15219811
    • Hsu YL, Kuo PL, Lin CC. The proliferative inhibition and apoptotic mechanism of saikosaponin d in human non-small cell lung cancer A549 cells. Life Sci 2004, 75:1231-1242. 10.1016/j.lfs.2004.03.008, 15219811.
    • (2004) Life Sci , vol.75 , pp. 1231-1242
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, C.C.3
  • 32
    • 4344636755 scopus 로고    scopus 로고
    • Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines
    • 15327837
    • Hsu YL, Kuo PL, Chiang LC, Lin CC. Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines. Cancer Lett 2004, 213:213-221. 10.1016/j.canlet.2004.03.044, 15327837.
    • (2004) Cancer Lett , vol.213 , pp. 213-221
    • Hsu, Y.L.1    Kuo, P.L.2    Chiang, L.C.3    Lin, C.C.4
  • 33
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: process and function
    • 18006683
    • Mizushima N. Autophagy: process and function. Genes Dev 2007, 21:2861-2873. 10.1101/gad.1599207, 18006683.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 34
    • 34548421950 scopus 로고    scopus 로고
    • Dual roles of autophagy in the survival of caenorhabditis elegans during starvation
    • 1950855, 17785524
    • Kang C, You YJ, Avery L. Dual roles of autophagy in the survival of caenorhabditis elegans during starvation. Genes Dev 2007, 21:2161-2171. 10.1101/gad.1573107, 1950855, 17785524.
    • (2007) Genes Dev , vol.21 , pp. 2161-2171
    • Kang, C.1    You, Y.J.2    Avery, L.3
  • 35
    • 33747431574 scopus 로고    scopus 로고
    • Amino acid starvation induced autophagic cell death in PC-12 cells: evidence for activation of caspase-3 but not calpain-1
    • 16703260
    • Sadasivan S, Waghray A, Larner SF, Dunn WA, Hayes RL, Wang KK. Amino acid starvation induced autophagic cell death in PC-12 cells: evidence for activation of caspase-3 but not calpain-1. Apoptosis 2006, 11:1573-1582. 10.1007/s10495-006-7690-6, 16703260.
    • (2006) Apoptosis , vol.11 , pp. 1573-1582
    • Sadasivan, S.1    Waghray, A.2    Larner, S.F.3    Dunn, W.A.4    Hayes, R.L.5    Wang, K.K.6
  • 36
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • 15680329
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005, 120:237-248. 10.1016/j.cell.2004.11.046, 15680329.
    • (2005) Cell , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 37
    • 34250864795 scopus 로고    scopus 로고
    • Protein turnover via autophagy: implications for metabolism
    • 17311494
    • Mizushima N, Klionsky DJ. Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr 2007, 27:19-40. 10.1146/annurev.nutr.27.061406.093749, 17311494.
    • (2007) Annu Rev Nutr , vol.27 , pp. 19-40
    • Mizushima, N.1    Klionsky, D.J.2
  • 39
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • 2696814, 18191218
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42. 10.1016/j.cell.2007.12.018, 2696814, 18191218.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 42
    • 33344458462 scopus 로고    scopus 로고
    • Pathophysiology and management of fever
    • Dalal S, Zhukovsky DS. Pathophysiology and management of fever. J Support Oncol 2006, 4:9-16.
    • (2006) J Support Oncol , vol.4 , pp. 9-16
    • Dalal, S.1    Zhukovsky, D.S.2
  • 44
    • 85067756551 scopus 로고
    • The therapeutic effect of experimental liver injury by xiao yao san
    • Han DW, Ma XH, Zhou LM, Zhao YC. The therapeutic effect of experimental liver injury by xiao yao san. Shan Xi Yi Yao Za Zhi 1976, 2:71-75.
    • (1976) Shan Xi Yi Yao Za Zhi , vol.2 , pp. 71-75
    • Han, D.W.1    Ma, X.H.2    Zhou, L.M.3    Zhao, Y.C.4
  • 45
    • 84907409401 scopus 로고    scopus 로고
    • Experimental study on material basis, efficacy and mechanism of antipyretic effect of Bupleuri Radix
    • Jin GT, Li B, Wang SR. Experimental study on material basis, efficacy and mechanism of antipyretic effect of Bupleuri Radix. J Chengdu Univ TCM 2013, 36:28-30.
    • (2013) J Chengdu Univ TCM , vol.36 , pp. 28-30
    • Jin, G.T.1    Li, B.2    Wang, S.R.3
  • 46
    • 85067761579 scopus 로고    scopus 로고
    • The progress of pharmacological study on the anti-pyretic effect of Chaihu
    • Zhang YB, Liang Y, Xia AJ. The progress of pharmacological study on the anti-pyretic effect of Chaihu. China Pharmaceuticals 2011, 20:79-80.
    • (2011) China Pharmaceuticals , vol.20 , pp. 79-80
    • Zhang, Y.B.1    Liang, Y.2    Xia, A.J.3
  • 47
    • 1542786396 scopus 로고    scopus 로고
    • Studies on antiendotoxin action of total saponins from radix Bupleuri
    • Liu YH, Chen YS, Xi W, Bai J. Studies on antiendotoxin action of total saponins from radix Bupleuri. Zhong Yao Cai 2003, 26:423-425.
    • (2003) Zhong Yao Cai , vol.26 , pp. 423-425
    • Liu, Y.H.1    Chen, Y.S.2    Xi, W.3    Bai, J.4
  • 49
    • 54449101892 scopus 로고    scopus 로고
    • Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response
    • 2562598, 18688877
    • Sir D, Chen WL, Choi J, Wakita T, Yen TS, Ou JH. Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response. Hepatology 2008, 48:1054-1061. 10.1002/hep.22464, 2562598, 18688877.
    • (2008) Hepatology , vol.48 , pp. 1054-1061
    • Sir, D.1    Chen, W.L.2    Choi, J.3    Wakita, T.4    Yen, T.S.5    Ou, J.H.6
  • 50
    • 65249108735 scopus 로고    scopus 로고
    • Autophagy genes in immunity
    • 2715365, 19381141
    • Virgin HW, Levine B. Autophagy genes in immunity. Nat Immunol 2009, 10:461-470. 10.1038/ni.1726, 2715365, 19381141.
    • (2009) Nat Immunol , vol.10 , pp. 461-470
    • Virgin, H.W.1    Levine, B.2
  • 51
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • 17272685
    • Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007, 315:1398-1401. 10.1126/science.1136880, 17272685.
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 53
    • 35848970794 scopus 로고    scopus 로고
    • Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease
    • 17921695
    • Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy 2007, 3:649-651. 10.4161/auto.5075, 17921695.
    • (2007) Autophagy , vol.3 , pp. 649-651
    • Massey, D.C.1    Parkes, M.2
  • 54
    • 84872719653 scopus 로고    scopus 로고
    • Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis
    • 3546319, 23326634
    • Ding Z, Liu S, Wang X, Khaidakov M, Dai Y, Mehta JL. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci Rep 2013, 3:1077. 3546319, 23326634.
    • (2013) Sci Rep , vol.3 , pp. 1077
    • Ding, Z.1    Liu, S.2    Wang, X.3    Khaidakov, M.4    Dai, Y.5    Mehta, J.L.6
  • 57
    • 70349737699 scopus 로고    scopus 로고
    • In vivo induction of the autophagic machinery in human bone marrow cells during Leishmania donovani complex infection
    • 19591960
    • Mitroulis I, Kourtzelis I, Papadopoulos VP, Mimidis K, Speletas M, Ritis K. In vivo induction of the autophagic machinery in human bone marrow cells during Leishmania donovani complex infection. Parasitol Int 2009, 58:475-477. 10.1016/j.parint.2009.07.002, 19591960.
    • (2009) Parasitol Int , vol.58 , pp. 475-477
    • Mitroulis, I.1    Kourtzelis, I.2    Papadopoulos, V.P.3    Mimidis, K.4    Speletas, M.5    Ritis, K.6
  • 58
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • 17767194
    • Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007, 7:767-777. 10.1038/nri2161, 17767194.
    • (2007) Nat Rev Immunol , vol.7 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 59
    • 0030309258 scopus 로고    scopus 로고
    • The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action
    • Zhou QL, Zhang ZQ, Nagasawa T, Hiai S. The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action. Yao Xue Xue Bao 1996, 31:496-501.
    • (1996) Yao Xue Xue Bao , vol.31 , pp. 496-501
    • Zhou, Q.L.1    Zhang, Z.Q.2    Nagasawa, T.3    Hiai, S.4
  • 60
    • 77953246193 scopus 로고    scopus 로고
    • Steroid-like compounds in Chinese medicines promote blood circulation via inhibition of Na+/K+ -ATPase
    • 20523340
    • Chen RJ, Chung TY, Li FY, Yang WH, Jinn TR, Tzen JT. Steroid-like compounds in Chinese medicines promote blood circulation via inhibition of Na+/K+ -ATPase. Acta Pharmacol Sin 2010, 31:696-702. 10.1038/aps.2010.61, 20523340.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 696-702
    • Chen, R.J.1    Chung, T.Y.2    Li, F.Y.3    Yang, W.H.4    Jinn, T.R.5    Tzen, J.T.6
  • 61
    • 85067741075 scopus 로고    scopus 로고
    • Activity of monomers of pentaeyclic triterpennoids of saikosaponines against methicillin-resistant staphylococcus aureus
    • Shen LL, Ye YK, Pan SL, Wu JM. Activity of monomers of pentaeyclic triterpennoids of saikosaponines against methicillin-resistant staphylococcus aureus. J Tongji UnivMed Sci 2008, 29:15-46.
    • (2008) J Tongji UnivMed Sci , vol.29 , pp. 15-46
    • Shen, L.L.1    Ye, Y.K.2    Pan, S.L.3    Wu, J.M.4
  • 62
    • 34147213589 scopus 로고    scopus 로고
    • Sho-saiko-to (xiao-chai-hu-tang) and crude saikosaponins inhibit hepatitis B virus in a stable HBV-producing cell line
    • 17436373
    • Chang JS, Wang KC, Liu HW, Chen MC, Chiang LC, Lin CC. Sho-saiko-to (xiao-chai-hu-tang) and crude saikosaponins inhibit hepatitis B virus in a stable HBV-producing cell line. Am J Chin Med 2007, 35:341-351. 10.1142/S0192415X07004862, 17436373.
    • (2007) Am J Chin Med , vol.35 , pp. 341-351
    • Chang, J.S.1    Wang, K.C.2    Liu, H.W.3    Chen, M.C.4    Chiang, L.C.5    Lin, C.C.6
  • 63
    • 85067756449 scopus 로고    scopus 로고
    • Suppresive effect on respiratory syncytial virus through combination of Ribavirin and Chaihu injection
    • Liao DS, Yu DW. Suppresive effect on respiratory syncytial virus through combination of Ribavirin and Chaihu injection. Chin J of mis diagnostics 2003, 3:230-231.
    • (2003) Chin J of mis diagnostics , vol.3 , pp. 230-231
    • Liao, D.S.1    Yu, D.W.2
  • 65
    • 66149145372 scopus 로고    scopus 로고
    • Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation
    • 19301261
    • Wong VK, Zhou H, Cheung SS, Li T, Liu L. Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation. J Cell Biochem 2009, 107:303-315. 10.1002/jcb.22126, 19301261.
    • (2009) J Cell Biochem , vol.107 , pp. 303-315
    • Wong, V.K.1    Zhou, H.2    Cheung, S.S.3    Li, T.4    Liu, L.5
  • 66
    • 85067756179 scopus 로고    scopus 로고
    • The study of the protective mechanism of hepatocyte in obstructive jaundice by saikosaponin
    • Liao B, Chen N. The study of the protective mechanism of hepatocyte in obstructive jaundice by saikosaponin. Guide of China Med 2011, 9:52-53.
    • (2011) Guide of China Med , vol.9 , pp. 52-53
    • Liao, B.1    Chen, N.2
  • 68
    • 84907404961 scopus 로고    scopus 로고
    • Effects of the extracts from Bupleurum Chinese DC on intracelluar free calcium concentration and vincristine accumulation in human hepatoma BEL-7402 cells
    • Han XH, Gai XD, Xue YJ, Chen M. Effects of the extracts from Bupleurum Chinese DC on intracelluar free calcium concentration and vincristine accumulation in human hepatoma BEL-7402 cells. Tumor 2006, 26:314-317.
    • (2006) Tumor , vol.26 , pp. 314-317
    • Han, X.H.1    Gai, X.D.2    Xue, Y.J.3    Chen, M.4
  • 69
    • 85067740739 scopus 로고    scopus 로고
    • A clinical study on the saikosaponin on FSC activation and extracellular matrix synthesis
    • Chen SA, Ben CG, Yang MJ. A clinical study on the saikosaponin on FSC activation and extracellular matrix synthesis. J Beijing University of TCM 1999, 22:31-34.
    • (1999) J Beijing University of TCM , vol.22 , pp. 31-34
    • Chen, S.A.1    Ben, C.G.2    Yang, M.J.3
  • 70
    • 35948964347 scopus 로고    scopus 로고
    • Hepatic stellate cells and liver fibrosis
    • Moreira RK. Hepatic stellate cells and liver fibrosis. Arch Pathol Lab Med 2007, 131:1728-1734.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1728-1734
    • Moreira, R.K.1
  • 71
    • 34249673939 scopus 로고    scopus 로고
    • Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury
    • 17534399
    • Fan J, Li X, Li P, Li N, Wang T, Shen H, Siow Y, Choy P, Gong Y. Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury. Biochem Cell Biol 2007, 85:189-195. 10.1139/O07-010, 17534399.
    • (2007) Biochem Cell Biol , vol.85 , pp. 189-195
    • Fan, J.1    Li, X.2    Li, P.3    Li, N.4    Wang, T.5    Shen, H.6    Siow, Y.7    Choy, P.8    Gong, Y.9
  • 72
  • 73
    • 85067781009 scopus 로고    scopus 로고
    • Cognition of traditional Chinese medicine about chronic pancreatitis and its treating progression
    • Huang HQ, Feng LY. Cognition of traditional Chinese medicine about chronic pancreatitis and its treating progression. Mod J Integrated Traditional Chin West Med 2007, 16:3762-3763.
    • (2007) Mod J Integrated Traditional Chin West Med , vol.16 , pp. 3762-3763
    • Huang, H.Q.1    Feng, L.Y.2
  • 74
    • 85067782249 scopus 로고    scopus 로고
    • Kinetics of enzymes secretion and mechanism stimulated by effective component of bupleurum in rat pancreatic acini. Modernization of Traditional Chinese Medicine and Materia Medica-World
    • Yang WX, Yu Y, Wang H, Zhao YY, Liang H, Wu XZ. Kinetics of enzymes secretion and mechanism stimulated by effective component of bupleurum in rat pancreatic acini. Modernization of Traditional Chinese Medicine and Materia Medica-World. Sci Technolx 2001, 3:21-24.
    • (2001) Sci Technolx , vol.3 , pp. 21-24
    • Yang, W.X.1    Yu, Y.2    Wang, H.3    Zhao, Y.Y.4    Liang, H.5    Wu, X.Z.6
  • 75
    • 84907394966 scopus 로고    scopus 로고
    • Therapeutic effects and mechanisms of chaihushugan decoction in experimental chronic pancreatitis rats
    • Chen Y, Zhou XL, Xue CR. Therapeutic effects and mechanisms of chaihushugan decoction in experimental chronic pancreatitis rats. Chi J Sur Integrated Traditional Wes Med 2010, 16:330-333.
    • (2010) Chi J Sur Integrated Traditional Wes Med , vol.16 , pp. 330-333
    • Chen, Y.1    Zhou, X.L.2    Xue, C.R.3
  • 76
    • 84907384239 scopus 로고    scopus 로고
    • Effect of chaihu shugan pulvis on dysfunction of pancreatic exocrine secretion in patients with chronic pancreatitis
    • Liu J, Zhao Z, Xue CR. Effect of chaihu shugan pulvis on dysfunction of pancreatic exocrine secretion in patients with chronic pancreatitis. Chinese J Sur Integrated Traditional and We Med 2010, 16:275-277.
    • (2010) Chinese J Sur Integrated Traditional and We Med , vol.16 , pp. 275-277
    • Liu, J.1    Zhao, Z.2    Xue, C.R.3
  • 79
    • 84907418657 scopus 로고    scopus 로고
    • A clinical study of chaihu shugan powder in the treatment of malignant tumor patients with depression
    • Fang XH, Wu Q, Han XM, Ren XL, Bai X, Zhu B, Li JY, Yang YH. A clinical study of chaihu shugan powder in the treatment of malignant tumor patients with depression. J Chin Oncol 2013, 19:726-729.
    • (2013) J Chin Oncol , vol.19 , pp. 726-729
    • Fang, X.H.1    Wu, Q.2    Han, X.M.3    Ren, X.L.4    Bai, X.5    Zhu, B.6    Li, J.Y.7    Yang, Y.H.8
  • 82
    • 85067772703 scopus 로고
    • Treatment of 15 cases of primary liver cancer by using supplemented xiao-chai-hu decoction
    • Chang MY. Treatment of 15 cases of primary liver cancer by using supplemented xiao-chai-hu decoction. J Practical Trad Chin Med 1995, 1:14.
    • (1995) J Practical Trad Chin Med , vol.1 , pp. 14
    • Chang, M.Y.1
  • 83
    • 84907409506 scopus 로고
    • Clinical observation of the treatment of primary liver cancer by using xiao-chai-hu decoction
    • Zhao HY. Clinical observation of the treatment of primary liver cancer by using xiao-chai-hu decoction. J Tradit Chin Med 1995, 18:32.
    • (1995) J Tradit Chin Med , vol.18 , pp. 32
    • Zhao, H.Y.1
  • 84
    • 85067751933 scopus 로고    scopus 로고
    • Clinical observation of the preventive effect of xiao-chai-hu-pian after surgery of liver cancer, attached with 40 case reports
    • Li SJ, Li L, Yi C. Clinical observation of the preventive effect of xiao-chai-hu-pian after surgery of liver cancer, attached with 40 case reports. J Chengdu Unv Tarditional Chin Med 2001, 25:16-18.
    • (2001) J Chengdu Unv Tarditional Chin Med , vol.25 , pp. 16-18
    • Li, S.J.1    Li, L.2    Yi, C.3
  • 85
    • 0025108722 scopus 로고
    • In vitro immunomodulatory effects of traditional Kampo medicine (sho-saiko-to: SST) on peripheral mononuclear cells in patients with AIDS
    • Inada Y, Watanabe K, Kamiyama M, Kanemitsu T, Clark WS, Lange M. In vitro immunomodulatory effects of traditional Kampo medicine (sho-saiko-to: SST) on peripheral mononuclear cells in patients with AIDS. Biomed Pharmacotherapy 1990, 44:17-19.
    • (1990) Biomed Pharmacotherapy , vol.44 , pp. 17-19
    • Inada, Y.1    Watanabe, K.2    Kamiyama, M.3    Kanemitsu, T.4    Clark, W.S.5    Lange, M.6
  • 86
    • 0028110031 scopus 로고
    • Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines
    • 7954360
    • Motoo Y, Sawabu N. Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. Cancer Lett 1994, 86:91-95. 10.1016/0304-3835(94)90184-8, 7954360.
    • (1994) Cancer Lett , vol.86 , pp. 91-95
    • Motoo, Y.1    Sawabu, N.2
  • 87
    • 84858740114 scopus 로고    scopus 로고
    • Experimental study on the expression of VEGF of the minor Bupleuri Decoction in mice with Lewis lung cancer cells
    • Liang JJ, Yin DF, Zhou LJ. Experimental study on the expression of VEGF of the minor Bupleuri Decoction in mice with Lewis lung cancer cells. Acta Chin Med Pharmacol 2008, 36:15-17.
    • (2008) Acta Chin Med Pharmacol , vol.36 , pp. 15-17
    • Liang, J.J.1    Yin, D.F.2    Zhou, L.J.3
  • 88
    • 33645512801 scopus 로고    scopus 로고
    • Bcl-2 inhibition of autophagy: a new route to cancer?
    • 16540632
    • Pattingre S, Levine B. Bcl-2 inhibition of autophagy: a new route to cancer?. Cancer Res 2006, 66:2885-2888. 10.1158/0008-5472.CAN-05-4412, 16540632.
    • (2006) Cancer Res , vol.66 , pp. 2885-2888
    • Pattingre, S.1    Levine, B.2
  • 89
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
    • 8761415
    • Bursch W, Ellinger A, Kienzl H, Torok L, Pandey S, Sikorska M, Walker R, Hermann RS. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996, 17:1595-1607. 10.1093/carcin/17.8.1595, 8761415.
    • (1996) Carcinogenesis , vol.17 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6    Walker, R.7    Hermann, R.S.8
  • 91
    • 84869155462 scopus 로고    scopus 로고
    • The miR-290-295 cluster suppresses autophagic cell death of melanoma cells
    • 3496171, 23150779
    • Chen Y, Liersch R, Detmar M. The miR-290-295 cluster suppresses autophagic cell death of melanoma cells. Sci Rep 2012, 2:808. 3496171, 23150779.
    • (2012) Sci Rep , vol.2 , pp. 808
    • Chen, Y.1    Liersch, R.2    Detmar, M.3
  • 93
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • 16148885
    • Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005, 5:726-734. 10.1038/nrc1692, 16148885.
    • (2005) Nat Rev Cancer , vol.5 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 95
    • 33750284176 scopus 로고    scopus 로고
    • Autophagy in cancer: good, bad, or both?
    • 17018585
    • Hippert MM, O'Toole PS, Thorburn A. Autophagy in cancer: good, bad, or both?. Cancer Res 2006, 66:9349-9351. 10.1158/0008-5472.CAN-06-1597, 17018585.
    • (2006) Cancer Res , vol.66 , pp. 9349-9351
    • Hippert, M.M.1    O'Toole, P.S.2    Thorburn, A.3
  • 96
    • 84894243088 scopus 로고    scopus 로고
    • Autophagic cell death and cancer
    • 3958902, 24566140
    • Shimizu S, Yoshida T, Tsujioka M, Arakawa S. Autophagic cell death and cancer. Int J Mol Sci 2014, 15:3145-3153. 10.3390/ijms15023145, 3958902, 24566140.
    • (2014) Int J Mol Sci , vol.15 , pp. 3145-3153
    • Shimizu, S.1    Yoshida, T.2    Tsujioka, M.3    Arakawa, S.4
  • 97
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
    • 15131264
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, Baehrecke EH, Lenardo MJ. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004, 304:1500-1502. 10.1126/science.1096645, 15131264.
    • (2004) Science , vol.304 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6    Baehrecke, E.H.7    Lenardo, M.J.8
  • 98
    • 22344444616 scopus 로고    scopus 로고
    • Does autophagy contribute to cell death?
    • 16874022
    • Debnath J, Baehrecke EH, Kroemer G. Does autophagy contribute to cell death?. Autophagy 2005, 1:66-74. 10.4161/auto.1.2.1738, 16874022.
    • (2005) Autophagy , vol.1 , pp. 66-74
    • Debnath, J.1    Baehrecke, E.H.2    Kroemer, G.3
  • 99
    • 77957663027 scopus 로고    scopus 로고
    • Autophagy in pancreatic cancer: an emerging mechanism of cell death
    • 3039747, 20818166
    • Mujumdar N, Saluja AK. Autophagy in pancreatic cancer: an emerging mechanism of cell death. Autophagy 2010, 6:997-998. 10.4161/auto.6.7.13334, 3039747, 20818166.
    • (2010) Autophagy , vol.6 , pp. 997-998
    • Mujumdar, N.1    Saluja, A.K.2
  • 100
    • 1642556763 scopus 로고    scopus 로고
    • Resveratrol-induced autophagocytosis in ovarian cancer cells
    • 14744787
    • Opipari AW, Tan L, Boitano AE, Sorenson DR, Aurora A, Liu JR. Resveratrol-induced autophagocytosis in ovarian cancer cells. Cancer Res 2004, 64:696-703. 10.1158/0008-5472.CAN-03-2404, 14744787.
    • (2004) Cancer Res , vol.64 , pp. 696-703
    • Opipari, A.W.1    Tan, L.2    Boitano, A.E.3    Sorenson, D.R.4    Aurora, A.5    Liu, J.R.6
  • 101
    • 84907409932 scopus 로고    scopus 로고
    • Influence of chaihushugan powder on lipid metabolism and liver function in nonalcoholic fatty liver rats
    • Li D, Jiang T, Fan HQ, Liang WN, Xiong KC, Tang CP. Influence of chaihushugan powder on lipid metabolism and liver function in nonalcoholic fatty liver rats. Zhong Yao Yao Li Yu Lin Chuang 2013, 29:8-12.
    • (2013) Zhong Yao Yao Li Yu Lin Chuang , vol.29 , pp. 8-12
    • Li, D.1    Jiang, T.2    Fan, H.Q.3    Liang, W.N.4    Xiong, K.C.5    Tang, C.P.6
  • 102
    • 84902540057 scopus 로고    scopus 로고
    • Studies of prescriptions corresponding to syndromes of xiaoyaosan decoction based on metabonomics
    • Beijing: Beijing University of Traditional Chinese Medicine, Chinese Medicine Department
    • Luo HG. Studies of prescriptions corresponding to syndromes of xiaoyaosan decoction based on metabonomics. PhD thesis 2007, Beijing: Beijing University of Traditional Chinese Medicine, Chinese Medicine Department.
    • (2007) PhD thesis
    • Luo, H.G.1
  • 103
    • 85067778065 scopus 로고    scopus 로고
    • The new evidence of the hypothesis of liver governs normal flow of qi relates to monoamine neurotransmitter and sex hormone and their regulative hormone
    • Shan Dong: Shan Dong University of Traditional Chinese Medicine, Traditional Chinese Medicine Department
    • Shi ZF. The new evidence of the hypothesis of liver governs normal flow of qi relates to monoamine neurotransmitter and sex hormone and their regulative hormone. Master thesis 2002, Shan Dong: Shan Dong University of Traditional Chinese Medicine, Traditional Chinese Medicine Department.
    • (2002) Master thesis
    • Shi, Z.F.1
  • 104
    • 33747363269 scopus 로고    scopus 로고
    • Glycogen autophagy in glucose homeostasis
    • 16781826
    • Kotoulas OB, Kalamidas SA, Kondomerkos DJ. Glycogen autophagy in glucose homeostasis. Pathol Res Pract 2006, 202:631-638. 10.1016/j.prp.2006.04.001, 16781826.
    • (2006) Pathol Res Pract , vol.202 , pp. 631-638
    • Kotoulas, O.B.1    Kalamidas, S.A.2    Kondomerkos, D.J.3
  • 107
    • 0016722649 scopus 로고
    • Structure and action of saikosaponins isolated from Bupleurum falcatum L. II. Metabolic actions of saikosaponins, especially a plasma cholesterol-lowering action
    • Yamamoto M, Kumagai A, Yamamura Y. Structure and action of saikosaponins isolated from Bupleurum falcatum L. II. Metabolic actions of saikosaponins, especially a plasma cholesterol-lowering action. Arzneimittelforschung 1975, 25:1240-1243.
    • (1975) Arzneimittelforschung , vol.25 , pp. 1240-1243
    • Yamamoto, M.1    Kumagai, A.2    Yamamura, Y.3
  • 108
    • 84907420435 scopus 로고    scopus 로고
    • The relationship between plasma monoamine neurotransmitters and serum lipid concentrations in depressive patients
    • Yuan YG, Zhang XB, Wu AQ, Zhang SN, Chen YQ. The relationship between plasma monoamine neurotransmitters and serum lipid concentrations in depressive patients. J Clin Psychological Med 2003, 13:67-68.
    • (2003) J Clin Psychological Med , vol.13 , pp. 67-68
    • Yuan, Y.G.1    Zhang, X.B.2    Wu, A.Q.3    Zhang, S.N.4    Chen, Y.Q.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.