Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice

Experimental Gerontology

Volumn 58, Issue , 2014, Pages 219-229

  Gesing, Adam ^a,b   Al Regaiey, Khalid A ^a,c   Bartke, Andrzej ^a   Masternak, Michal M ^d  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Ames dwarf mice; Calorie restriction; Growth hormone; MAPK signaling; Metabolism; Transcription factors

Indexed keywords

ADIPONECTIN; CHOLESTEROL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C LAMBDA; PROTEIN KINASE C ZETA; RECOMBINANT GROWTH HORMONE; SODIUM CHLORIDE; BIOLOGICAL MARKER; GROWTH HORMONE; FATTY ACID; GLUCOSE TRANSPORTER 2; INSULIN RECEPTOR BETA SUBUNIT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE C XI; PROTEIN SERINE THREONINE KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; GLUCOSE BLOOD LEVEL; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; INSULIN BLOOD LEVEL; LIFESPAN; LIVER LEVEL; LONGEVITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; DWARFISM, PITUITARY; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; LIVER; METABOLISM; MULTIMODALITY CANCER THERAPY; MUTANT MOUSE STRAIN; PATHOPHYSIOLOGY; PHENOTYPE; TIME; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; BIOMARKERS; CALORIC RESTRICTION; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; DWARFISM, PITUITARY; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENOTYPE; GROWTH HORMONE; HORMONE REPLACEMENT THERAPY; LIVER; LONGEVITY; MALE; MICE; MICE, MUTANT STRAINS; PHENOTYPE; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84907352763     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.08.010     Document Type: Article

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