Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice

Cardiovascular Research

Volumn 103, Issue 4, 2014, Pages 473-484

  Deng, Jiao ^a,b   Zhang, Junfeng ^a   Feng, Chenzhuo ^a   Xiong, Lize ^b   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral vascular remodelling; High fat diet; Ischemic stroke; Matrix metalloprotease; Mouse

Indexed keywords

CHOLESTEROL; GELATINASE B; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LIPID; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL; MMP9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BLOOD BRAIN BARRIER; BODY WEIGHT; BRAIN CORTEX; BRAIN EDEMA; BRAIN FUNCTION; BRAIN HEMORRHAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN SIZE; BRAIN TISSUE; CAPILLARY DENSITY; CEREBROVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPERLIPIDEMIA; HYPOXIC ISCHEMIC ENCEPHALOPATHY; LIPID BLOOD LEVEL; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; MALE; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; OBESITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; ARTERY OCCLUSION; BRAIN INFARCTION; BRAIN INJURY; CEREBRAL ARTERY DISEASE; CEREBRAL VASCULAR REMODELLING; REGENERATION; TISSUE REGENERATION; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; COMPLICATION; DEFICIENCY; DISEASE MODEL; ENZYMOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; VASCULAR REMODELING;

ANIMALS; BLOOD GLUCOSE; BRAIN INJURIES; BRAIN ISCHEMIA; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; OBESITY; VASCULAR REMODELING;

EID: 84907351514     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu154     Document Type: Article

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