Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB

Neuroscience

Volumn 261, Issue , 2014, Pages 1-10

  Zhang, J ^a,b   Jiang, W ^b   Zuo, Z ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Neuroinflammation; Nuclear factor B; Pyrrolidine dithiocarbamate; Rat; Surgery

Indexed keywords

BRAIN PROTEIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1; PYRROLIDINE DITHIOCARBAMATE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARNES MAZE TEST; COGNITIVE DEFECT; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; FEAR; HIPPOCAMPAL CA3 REGION; INHIBITION KINETICS; LEARNING DISORDER; LONG TERM MEMORY; MALE; MEMORY DISORDER; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

NEUROINFLAMMATION; NUCLEAR FACTOR ΚB; PYRROLIDINE DITHIOCARBAMATE; RAT; SURGERY;

ANESTHETICS; ANIMALS; BUPRENORPHINE; CAROTID ARTERIES; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); ENCEPHALITIS; FEAR; HIPPOCAMPUS; MALE; MATRIX METALLOPROTEINASE 9; MAZE LEARNING; NEUROPROTECTIVE AGENTS; NF-KAPPA B; POSTOPERATIVE COMPLICATIONS; PROPOFOL; PYRROLIDINES; RATS; RATS, INBRED F344; THIOCARBAMATES;

EID: 84892448111     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.12.034     Document Type: Article

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