Diet-induced obesity causes cerebral vessel remodeling and increases the damage caused by ischemic stroke

Microvascular Research

Volumn 78, Issue 1, 2009, Pages 100-106

  Deutsch, Christian ^a   Portik Dobos, Vera ^a   Smith, Anita D ^a   Ergul, Adviye ^a   Dorrance, Anne M ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Hypertension; Matrix metalloproteinase; Obesity; Vessel remodeling

Indexed keywords

COLLAGEN TYPE 1; COLLAGENASE 3; GELATINASE A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL STIFFNESS; ARTERY COMPLIANCE; ARTERY DIAMETER; ARTERY WALL; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID DIET; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BRAIN ISCHEMIA; CEREBRAL ARTERIES; CEREBRAL INFARCTION; DIET; HYPERTENSION; MALE; MATRIX METALLOPROTEINASES; MIDDLE CEREBRAL ARTERY; OBESITY; RATS; RATS, SPRAGUE-DAWLEY; STROKE;

RATTUS;

EID: 67349155278     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.04.004     Document Type: Article

References (38)

1. Bagust A., et al. The projected health care burden of Type 2 diabetes in the UK from 2000 to 2060. Diabet. Med. 19 Suppl. 4 (2002) 1-5
2. Baumbach G.L., and Heistad D.D. Remodeling of cerebral arterioles in chronic hypertension. Hypertension 13 (1989) 968-972
3. Bouvet C., et al. Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition. Hypertension 45 (2005) 432-437
4. Carroll J.F., et al. Hypertension, cardiac hypertrophy, and neurohumoral activity in a new animal model of obesity. Am. J. Physiol. 271 (1996) H373-H378
5. Cipolla M.J., et al. Postischemic attenuation of cerebral artery reactivity is increased in the presence of tissue plasminogen activator. Stroke 31 (2000) 940-945
6. Coulson R.J., et al. Effects of ischemia and myogenic activity on active and passive mechanical properties of rat cerebral arteries. Am. J. Physiol. Heart Circ. Physiol. 283 (2002) H2268-H2275
7. Coyle P., and Jokelainen P.T. Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) and Wistar Kyoto (WKY) rats. Stroke 14 (1983) 605-611
8. Dobrian A.D., et al. Development of hypertension in a rat model of diet-induced obesity. Hypertension 35 (2000) 1009-1015
9. Ergul A., et al. Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model of type 2 Diabetes. BMC. Neurol. 7 (2007)
10. Festa A., et al. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102 (2000) 42-47
11. Grundy S.M., et al. Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 100 (1999) 1134-1146
12. Hall J.E. Louis K. Dahl Memorial Lecture. Renal and cardiovascular mechanisms of hypertension in obesity. Hypertension 23 (1994) 381-394
13. Hall J.E., et al. Abnormal kidney function as a cause and a consequence of obesity hypertension. Clin. Exp. Pharmacol. Physiol. 25 (1998) 58-64
14. Harper S.L., et al. Arterial and microvascular contributions to cerebral cortical autoregulation in rats. Am. J. Physiol. 246 (1984) H17-24
15. Harris A.K., et al. Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1. Diabetes 54 (2005) 2638-2644
16. Hirose H., et al. The obese gene product, leptin: possible role in obesity-related hypertension in adolescents. J. Hypertens. 16 2007-12 (1998)
17. Kernan W.N., and Inzucchi S.E. Type 2 diabetes mellitus and insulin resistance: stroke prevention and management. Curr. Treat. Options. Neurol. 6 (2004) 443-450
18. Klein B.E., et al. Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in beaver dam. Diabetes Care. 25 (2002) 1790-1794
19. Kopelman P.G., et al. Impaired growth hormone response to growth hormone releasing factor and insulin-hypoglycaemia in obesity. Clin. Endocrinol. (Oxf). 23 (1985) 87-94
20. Kotsis T., et al. Impact of obesity in intima media thickness of carotid arteries. Obesity. (Silver. Spring). 14 (2006) 1708-1715
21. Kvaavik E., et al. Predictors and tracking of body mass index from adolescence into adulthood: follow-up of 18 to 20 years in the Oslo Youth Study. Arch. Pediatr. Adolesc. Med. 157 (2003) 1212-1218
22. Levin B.E., et al. Relationship between sympathetic activity and diet-induced obesity in two rat strains. Am. J. Physiol. 245 (1983) R364-R371
23. Mayanagi K., et al. Acute treatment with rosuvastatin protects insulin resistant (C57BL/6J ob/ob) mice against transient cerebral ischemia. J. Cereb. Blood Flow Metab. 28 (2008) 1927-1935
24. Mokdad A.H., et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. Jama. 289 (2003) 76-79
25. Osmond J.M., et al. Obesity increases blood pressure, cerebral vascular remodeling, and severity of stroke in the Zucker rat. Hypertension 53 (2009) 381-386
26. Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37 (1988) 1595-1607
27. Rigsby C.S., et al. Intact female stroke-prone hypertensive rats lack responsiveness to mineralocorticoid receptor antagonists. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2007)
28. Rigsby C.S., et al. Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. Microvasc. Res. 73 (2007) 198-205
29. Rocchini A.P. Childhood obesity and a diabetes epidemic. N. Engl. J. Med. 346 (2002) 854-855
30. Rosamond W., et al. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117 (2008) e25-e146
31. Smith A.D., and Dorrance A.M. Arachidonic acid induces augmented vasoconstriction via cyclooxygenase 1 in the aorta from rats fed a high-fat diet. Prostaglandins. Leukot. Essent. Fatty. Acids. 75 (2006) 43-49
32. Smith A.D., et al. Obesity-induced hypertension develops in young rats independently of the renin-angiotensin-aldosterone system. Exp. Biol. Med. (Maywood). 231 (2006) 282-287
33. Swanson R.A., et al. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10 (1990) 290-293
34. Van Gaal L.F., et al. Human obesity: from lipid abnormalities to lipid oxidation. Int. J. Obes. Relat. Metab. Disord. 19 Suppl. 3 (1995) S21-S26
35. Wang M.H., et al. Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension. Hypertension 42 (2003) 594-599
36. Whitaker R.C., et al. Predicting obesity in young adulthood from childhood and parental obesity. N. Engl. J. Med. 337 (1997) 869-873
37. Wu Y., and Smas C.M. Wdnm1-like, a new adipokine with a Role in MMP-2 activation. Am. J. Physiol. Endocrinol. Metab. (2008)
38. Zhou Y., et al. Gender differences of renal CYP-derived eicosanoid synthesis in rats fed a high-fat diet. Am. J. Hypertens. 18 (2005) 530-537