Deficient eNOS Phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size

Stroke

Volumn 44, Issue 11, 2013, Pages 3183-3188

  Li, Qian ^a   Atochin, Dmitriy ^a   Kashiwagi, Satoshi ^a   Earle, John ^a   Wang, Annie ^a   Mandeville, Emiri ^a   Hayakawa, Kazuhide ^a   D'Uscio, Livius V ^b   Lo, Eng H ^a   Katusic, Zvonimir ^b   Sessa, William ^c   Huang, Paul L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MAYO CLINIC   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetes mellitus; Endothelial cells; Nitric oxide

Indexed keywords

ACETYLCHOLINE; ASPARTIC ACID; SERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL GAS; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; BRAIN CAPILLARY DENSITY; BRAIN CIRCULUS ARTERIOSUS; BRAIN INFARCTION SIZE; CAPILLARY DENSITY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIABETIC VASCULAR DYSFUNCTION; ENDOTHELIAL NITRIC OXIDE SYNTHASE PHOSPHORYLATION; ENZYME ACTIVITY; GENE MUTATION; HEART RATE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OUTCOME ASSESSMENT; PHOSPHORYLATION; PRIORITY JOURNAL; VASCULAR DISEASE;

DIABETES MELLITUS; ENDOTHELIAL CELLS; NITRIC OXIDE;

ANIMALS; CROSSES, GENETIC; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; STROKE; TREATMENT OUTCOME; VASCULAR DISEASES;

EID: 84888287927     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002073     Document Type: Article

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