Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia: Role of lipid peroxidation and calpain-1/2, matrix metalloproteinase-2/9, and rhoa overactivation

Stroke

Volumn 42, Issue 11, 2011, Pages 3238-3244

  Elali, Ayman ^a   Doeppner, Thorsten R ^a   Zechariah, Anil ^a   Hermann, Dirk M ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

apolipoprotein E; hyperlipidemia; lipid peroxidation; middle cerebral artery occlusion; Rho GTPase

Indexed keywords

APOLIPOPROTEIN E; CALPAIN 1; CALPAIN 2; DNA FRAGMENT; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN G; LOW DENSITY LIPOPROTEIN; OCCLUDIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN EDEMA; BRAIN ISCHEMIA; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HYPERLIPIDEMIA; LIPID DIET; LIPID PEROXIDATION; LIPID STORAGE; MALE; MOUSE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION; WILD TYPE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN ISCHEMIA; CALPAIN; CAPILLARY PERMEABILITY; ENZYME ACTIVATION; HYPERLIPIDEMIAS; LIPID PEROXIDATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RHO GTP-BINDING PROTEINS;

EID: 80054994555     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.615559     Document Type: Article

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