-
1
-
-
18644373013
-
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism
-
Stewart, S. A. et al. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proc. Natl Acad. Sci. USA 99, 12606-12611 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 12606-12611
-
-
Stewart, S.A.1
-
2
-
-
79952017845
-
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
-
Martinez, P. & Blasco, M. A. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nat. Rev. Cancer 11, 161-176 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 161-176
-
-
Martinez, P.1
Blasco, M.A.2
-
3
-
-
67650065306
-
Telomerase modulates Wnt signalling by association with target gene chromatin
-
Park, J. I. et al. Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 460, 66-72 (2009).
-
(2009)
Nature
, vol.460
, pp. 66-72
-
-
Park, J.I.1
-
4
-
-
84870616090
-
Telomerase directly regulates NF-kappaB-dependent transcription
-
Ghosh, A. et al. Telomerase directly regulates NF-kappaB-dependent transcription. Nat. Cell. Biol. 14, 1270-1281 (2012).
-
(2012)
Nat. Cell. Biol.
, vol.14
, pp. 1270-1281
-
-
Ghosh, A.1
-
5
-
-
78650900215
-
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
-
Zhong, F. et al. Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita. Genes Dev. 25, 11-16 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 11-16
-
-
Zhong, F.1
-
6
-
-
84875491664
-
Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria
-
Chiodi, I. & Mondello, C. Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria. Front. Oncol. 2, 133 (2012).
-
(2012)
Front. Oncol.
, vol.2
, pp. 133
-
-
Chiodi, I.1
Mondello, C.2
-
7
-
-
31944444988
-
Cell cycle-regulated trafficking of human telomerase to telomeres
-
DOI 10.1091/mbc.E05-09-0903
-
Tomlinson, R. L., Ziegler, T. D., Supakorndej, T., Terns, R. M. & Terns, M. P. Cell cycle-regulated trafficking of human telomerase to telomeres. Mol. Biol. Cell 17, 955-965 (2006). (Pubitemid 43191127)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.2
, pp. 955-965
-
-
Tomlinson, R.L.1
Ziegler, T.D.2
Supakorndej, T.3
Terns, R.M.4
Terns, M.P.5
-
8
-
-
84893864827
-
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase
-
Lee, J. H. et al. Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem. Cell Biol. 141, 137-152 (2014).
-
(2014)
Histochem. Cell Biol.
, vol.141
, pp. 137-152
-
-
Lee, J.H.1
-
9
-
-
0037025334
-
The nucleolar localization domain of the catalytic subunit of human telomerase
-
DOI 10.1074/jbc.M201227200
-
Etheridge, K. T. et al. The nucleolar localization domain of the catalytic subunit of human telomerase. J. Biol. Chem. 277, 24764-24770 (2002). (Pubitemid 34952008)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.27
, pp. 24764-24770
-
-
Etheridge, K.T.1
Banik, S.S.R.2
Armbruster, B.N.3
Zhu, Y.4
Terns, R.M.5
Terns, M.P.6
Counter, C.M.7
-
10
-
-
48049088130
-
Nucleolar localization of TERT is unrelated to telomerase function in human cells
-
Lin, J. et al. Nucleolar localization of TERT is unrelated to telomerase function in human cells. J. Cell. Sci. 121, 2169-2176 (2008).
-
(2008)
J. Cell. Sci.
, vol.121
, pp. 2169-2176
-
-
Lin, J.1
-
11
-
-
33746923402
-
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: Nucleolin and telomerase cross paths
-
Wu, Y. L. et al. Immunodetection of human telomerase reverse- transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths. J. Cell. Sci. 119, 2797-2806 (2006).
-
(2006)
J. Cell. Sci.
, vol.119
, pp. 2797-2806
-
-
Wu, Y.L.1
-
12
-
-
13944280970
-
A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues
-
DOI 10.1158/0008-5472.CAN-04-3046
-
Ritz, J. M. et al. A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues. Cancer Res. 65, 1187-1196 (2005). (Pubitemid 40270143)
-
(2005)
Cancer Research
, vol.65
, Issue.4
, pp. 1187-1196
-
-
Ritz, J.M.1
Kuhle, O.2
Riethdorf, S.3
Sipos, B.4
Deppert, W.5
Englert, C.6
Gunes, C.7
-
13
-
-
0037047643
-
Est1p as a cell cycle-regulated activator of telomere-bound telomerase
-
DOI 10.1126/science.1074968
-
Taggart, A. K., Teng, S. C. & Zakian, V. A. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297, 1023-1026 (2002). (Pubitemid 34856037)
-
(2002)
Science
, vol.297
, Issue.5583
, pp. 1023-1026
-
-
Taggart, A.K.P.1
Teng, S.-C.2
Zakian, V.A.3
-
14
-
-
33846692105
-
TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase
-
DOI 10.1038/nature05469, PII NATURE05469
-
Xin, H. et al. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Nature 445, 559-562 (2007). (Pubitemid 46197638)
-
(2007)
Nature
, vol.445
, Issue.7127
, pp. 559-562
-
-
Xin, H.1
Liu, D.2
Wan, M.3
Safari, A.4
Kim, H.5
Sun, W.6
O'Connor, M.S.7
Songyang, Z.8
-
15
-
-
79959998220
-
The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation
-
Sirma, H. et al. The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation. Gastroenterology 141, 326-337 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 326-337
-
-
Sirma, H.1
-
16
-
-
70349906783
-
Mechanism of dominant-negative telomerase function
-
Nguyen, B. N., Elmore, L. W. & Holt, S. E. Mechanism of dominant-negative telomerase function. Cell Cycle 8, 3227-3233 (2009).
-
(2009)
Cell Cycle
, vol.8
, pp. 3227-3233
-
-
Nguyen, B.N.1
Elmore, L.W.2
Holt, S.E.3
-
17
-
-
84893864827
-
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase
-
Lee, J. H. et al. Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem. Cell Biol. 141, 137-152 (2014).
-
(2014)
Histochem. Cell Biol.
, vol.141
, pp. 137-152
-
-
Lee, J.H.1
-
18
-
-
84860179172
-
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation
-
Katz, S. F. et al. Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation. Gastroenterology 142, 1229-1239 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 1229-1239
-
-
Katz, S.F.1
-
19
-
-
84855897301
-
TFIIH is an elongation factor of RNA polymerase i
-
Assfalg, R. et al. TFIIH is an elongation factor of RNA polymerase I. Nucleic Acids Res. 40, 650-659 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 650-659
-
-
Assfalg, R.1
-
20
-
-
0035984715
-
Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression
-
DOI 10.1038/nbt0602-587
-
Shi, S. et al. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat. Biotechnol. 20, 587-591 (2002). (Pubitemid 34595152)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.6
, pp. 587-591
-
-
Shi, S.1
Gronthos, S.2
Chen, S.3
Reddi, A.4
Counter, C.M.5
Robey, P.G.6
Wang, C.-Y.7
-
21
-
-
0036615949
-
Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage
-
Forsythe, H. L., Elmore, L. W., Jensen, K. O., Landon, M. R. & Holt, S. E. Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage. Int. J. Oncol. 20, 1137-1143 (2002).
-
(2002)
Int. J. Oncol.
, vol.20
, pp. 1137-1143
-
-
Forsythe, H.L.1
Elmore, L.W.2
Jensen, K.O.3
Landon, M.R.4
Holt, S.E.5
-
22
-
-
1542306071
-
Telomerase as a growth-promoting factor
-
Gorbunova, V. & Seluanov, A. Telomerase as a growth-promoting factor. Cell Cycle 2, 534-537 (2003).
-
(2003)
Cell Cycle
, vol.2
, pp. 534-537
-
-
Gorbunova, V.1
Seluanov, A.2
-
23
-
-
0034674714
-
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6
-
DOI 10.1126/science.288.5473.2045
-
Volarevic, S. et al. Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. Science 288, 2045-2047 (2000). (Pubitemid 30397685)
-
(2000)
Science
, vol.288
, Issue.5473
, pp. 2045-2047
-
-
Volarevic, S.1
Stewart, M.J.2
Ledermann, B.3
Zilberman, F.4
Terracciano, L.5
Montini, E.6
Grompe, M.7
Kozma, S.C.8
Thomas, G.9
-
24
-
-
11144315536
-
Key role of the achievement of an appropriate ribosomal RNA complement for G1-S phase transition in H4-II-E-C3 rat hepatoma cells
-
DOI 10.1002/jcp.20144
-
Derenzini, M. et al. Key role of the achievement of an appropriate ribosomal RNA complement for G1-S phase transition in H4-II-E-C3 rat hepatoma cells. J. Cell. Physiol. 202, 483-491 (2005). (Pubitemid 40041319)
-
(2005)
Journal of Cellular Physiology
, vol.202
, Issue.2
, pp. 483-491
-
-
Derenzini, M.1
Montanaro, L.2
Chilla, A.3
Tosti, E.4
Vici, M.5
Barbieri, S.6
Govoni, M.7
Mazzini, G.8
Trere, D.9
-
25
-
-
79951847459
-
Targeting RNA polymerase i with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth
-
Drygin, D. et al. Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth. Cancer Res. 71, 1418-1430 (2009).
-
(2009)
Cancer Res.
, vol.71
, pp. 1418-1430
-
-
Drygin, D.1
-
26
-
-
0036787840
-
Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
-
Gonzalez-Suarez, E., Flores, J. M. & Blasco, M. A. Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development. Mol. Cell. Biol. 22, 7291-7301 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7291-7301
-
-
Gonzalez-Suarez, E.1
Flores, J.M.2
Blasco, M.A.3
-
27
-
-
0029941676
-
Telomerase activation in mouse mammary tumors: Lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation
-
Broccoli, D., Godley, L. A., Donehower, L. A., Varmus, H. E. & de Lange, T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Mol. Cell. Biol. 16, 3765-3772 (1996). (Pubitemid 26199896)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.7
, pp. 3765-3772
-
-
Broccoli, D.1
Godley, L.A.2
Donehower, L.A.3
Varmus, H.E.4
De Lange, T.5
-
28
-
-
0037062454
-
Constitutive telomerase expression promotes mammary carcinomas in aging mice
-
DOI 10.1073/pnas.112515399
-
Artandi, S. E. et al. Constitutive telomerase expression promotes mammary carcinomas in aging mice. Proc. Natl Acad. Sci. USA 99, 8191-8196 (2002). (Pubitemid 34651028)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.12
, pp. 8191-8196
-
-
Artandi, S.E.1
Alson, S.2
Tietze, M.K.3
Sharpless, N.E.4
Ye, S.5
Greenberg, R.A.6
Castrillon, D.H.7
Horner, J.W.8
Weiler, S.R.9
Carrasco, R.D.10
DePinho, R.A.11
-
29
-
-
21244502260
-
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
-
DOI 10.1074/jbc.M502782200
-
Li, S., Crothers, J., Haqq, C. M. & Blackburn, E. H. Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. J. Biol. Chem. 280, 23709-23717 (2005). (Pubitemid 40884853)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.25
, pp. 23709-23717
-
-
Li, S.1
Crothers, J.2
Haqq, C.M.3
Blackburn, E.H.4
-
30
-
-
78549257138
-
The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines
-
Joseph, I. et al. The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines. Cancer Res. 70, 9494-9504 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 9494-9504
-
-
Joseph, I.1
-
31
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
DOI 10.1038/13495
-
Hahn, W. C. et al. Inhibition of telomerase limits the growth of human cancer cells. Nat. Med. 5, 1164-1170 (1999). (Pubitemid 29474421)
-
(1999)
Nature Medicine
, vol.5
, Issue.10
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Kurachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.M.8
Meyerson, M.9
Weinberg, R.A.10
-
32
-
-
0032485416
-
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
-
Counter, C. M. et al. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2)The catalytic subunit of telomerase. Oncogene 16, 1217-1222 (1998). (Pubitemid 28127521)
-
(1998)
Oncogene
, vol.16
, Issue.9
, pp. 1217-1222
-
-
Counter, C.M.1
Meyerson, M.2
Eaton, E.N.3
Ellisen, L.W.4
Caddle, S.D.5
Haber, D.A.6
Weinberg, R.A.7
-
33
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
DOI 10.1038/nature03836
-
Sarin, K. Y. et al. Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436, 1048-1052 (2005). (Pubitemid 41191691)
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
Lee, E.4
Tennen, R.I.5
Wang, E.6
Artandi, M.K.7
Oro, A.E.8
Artandi, S.E.9
-
34
-
-
70249114371
-
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA
-
Maida, Y. et al. An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Nature 461, 230-235 (2009).
-
(2009)
Nature
, vol.461
, pp. 230-235
-
-
Maida, Y.1
-
35
-
-
84855493321
-
Maintenance of tumor initiating cells of defined genetic composition by nucleostemin
-
Okamoto, N. et al. Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. Proc. Natl Acad. Sci. USA 108, 20388-20393 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 20388-20393
-
-
Okamoto, N.1
-
36
-
-
84855537673
-
Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling
-
Shkreli, M. et al. Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling. Nat. Med. 18, 111-119 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 111-119
-
-
Shkreli, M.1
-
37
-
-
84879978463
-
Implications of telomereindependent activities of telomerase reverse transcriptase in human cancer
-
Ding, D., Zhou, J., Wang, M. & Cong, Y. S. Implications of telomereindependent activities of telomerase reverse transcriptase in human cancer. FEBS J. 280, 3205-3211 (2013).
-
(2013)
FEBS J.
, vol.280
, pp. 3205-3211
-
-
Ding, D.1
Zhou, J.2
Wang, M.3
Cong, Y.S.4
-
38
-
-
84893345584
-
Telomerase reverse transcriptase in the regulation of gene expression
-
Zhou, J., Ding, D., Wang, M. & Cong, Y. S. Telomerase reverse transcriptase in the regulation of gene expression. BMB Rep. 47, 8-14 (2014).
-
(2014)
BMB Rep.
, vol.47
, pp. 8-14
-
-
Zhou, J.1
Ding, D.2
Wang, M.3
Cong, Y.S.4
-
39
-
-
0037428129
-
Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification
-
DOI 10.1126/science.1079447
-
Ruggero, D. et al. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science 299, 259-262 (2003). (Pubitemid 36125213)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 259-262
-
-
Ruggero, D.1
Grisendi, S.2
Piazza, F.3
Rego, E.4
Mari, F.5
Rao, P.H.6
Cordon-Cardo, C.7
Pandolfi, P.P.8
-
40
-
-
0036135638
-
UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat
-
DOI 10.1128/MCB.22.2.657-668.2002
-
O'Sullivan, A. C., Sullivan, G. J. & McStay, B. UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat. Mol. Cell. Biol. 22, 657-668 (2002). (Pubitemid 34027509)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.2
, pp. 657-668
-
-
O'Sullivan, A.C.1
Sullivan, G.J.2
McStay, B.3
-
41
-
-
0001276586
-
Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
-
Higgins, G. M. & Anderson, R. M. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch. Pathol. 12, 186-202 (1931).
-
(1931)
Arch. Pathol.
, vol.12
, pp. 186-202
-
-
Higgins, G.M.1
Anderson, R.M.2
|