UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

Molecular and Cellular Biology

Volumn 22, Issue 2, 2002, Pages 657-668

  O'Sullivan, A C ^a   Sullivan, G J ^a   McStay, B ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE; HIGH MOBILITY GROUP PROTEIN; RIBOSOME DNA; SPACER DNA; STRUCTURAL PROTEIN; TATA BINDING PROTEIN; UNCLASSIFIED DRUG; UPSTREAM BINDING FACTOR;

ANIMAL CELL; ARTICLE; CHROMATIN; CHROMOSOME NOR; CONTROLLED STUDY; DNA TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; REGULATOR GENE; VERTEBRATE; XENOPUS;

ANIMALS; BINDING SITES; CELL LINE; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; GENES, REGULATOR; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MACROMOLECULAR SUBSTANCES; MICE; NUCLEOLUS ORGANIZER REGION; POL1 TRANSCRIPTION INITIATION COMPLEX PROTEINS; PROMOTER REGIONS (GENETICS); REPETITIVE SEQUENCES, NUCLEIC ACID; RNA POLYMERASE I; TRANSCRIPTION FACTORS; XENOPUS LAEVIS;

ANIMALIA; MAMMALIA; VERTEBRATA;

EID: 0036135638     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.2.657-668.2002     Document Type: Article

References (62)

1. Comparative mapping of human alphoid sequences in great apes using fluorescence in situ hybridization
2. The RNA polymerase I transcription factor xUBF contains 5 tandemly repeated HMG homology boxes
3. Short-range DNA looping by the Xenopus HMG-box transcription factor, xUBF
4. Association of the nucleolar transcription factor UBF with the transcriptionally inactive rRNA genes of pronuclei and early Xenopus embryos
5. Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis
6. Upstream binding factor stabilizes Rib 1, the TATA-binding-protein-containing Xenopus laevis RNA polymerase I transcription factor, by multiple protein interactions in a DNA-independent manner
7. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p
8. Sequence organization of the spacer DNA in a ribosomal gene unit of Xenopus laevis
9. HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF
10. Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor
11. A homologous subfamily of satellite III DNA on human chromosomes 14 and 22
12. Genomic sequencing
13. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1
14. Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle
15. The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acids
16. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
17. Complete sequence of the 43-kb human ribosomal DNA repeat: Analysis of the intergenic spacer
18. Regulation of mammalian ribosomal gene transcription by RNA polymerase 1
19. Electron tomography of metaphase nucleolar organizer regions: Evidence for a twisted-loop organization
20. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins
21. In vivo evidence that TATA-binding protein/SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive
22. Involvement of in situ conformation of ribosomal genes and selective distribution of upstream binding factor in rRNA transcription
23. Nucleosome binding by the polymerase I transactivator upstream binding factor displaces linker histone H1
24. 1
25. Functional differences between the two splice variants of the nucleolar transcription factor UBF: The second HMG box determines specificity of DNA binding and transcriptional activity
26. Enhancer-like properties of the 60/81 bp elements in the ribosomal gene spacer ofXenopus laevis
27. Molecular analysis of the heterogeneity region of the human ribosomal spacer
28. In vitro transcription of human ribosomal RNA genes by RNA polymerase I
29. Recognition of the Xenopus ribosomal core promoter by the transcription factor xUBF involves multiple HMG box domains and leads to an xUBF interdomain interaction
30. Repeated genes in eukaryotes
31. Some properties of isolated nudeoli from guinea-pig liver
32. xUBF and Rib 1 are both required for formation of a stable polymerase I promoter complex in X. laevis
33. The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter
34. A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription
35. hRRN3 is essential ill in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters
36. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human
37. Virtually the entire Xenopus laevis rDNA multikilobase intergenic spacer serves to stimulate polymerase I transcription
38. Quantitative aspects of isolation of nucleoli of the Walker carcinosarcoma and liver of the rat
39. Distribution of GAGA protein on Drosophila genes in vivo
40. Identification of two forms of the RNA polymerase I transcription factor UBF
41. Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation
42. Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription
43. The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF
44. The RNA polymerase 1 transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA
45. Cooperative binding of the Xenopus RNA polymerase I transcription factor xUBF to repetitive ribosomal gene enhancers
46. Morphology of transcription at cellular and molecular levels
47. Regulatory elements of the generic ribosomal gene
48. UBF, an architectural element for RNA polymerase I promoters
49. Autoantibody to RNA polymerase I in scleroderma sera
50. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs
51. Localization of the RNA polymerase I transcription factor hUBF during the cell cycle
52. TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription
53. Contiguous arrays of satellites 1, 3, and beta form a 1.5-Mb domain on chromosome 22p
54. In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing
55. Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli
56. Assignment of human satellite 1 DNA as revealed by fluorescent in situ hybridization with oligonuclectides
57. 1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF
58. Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF
59. Two homeo domain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryos
60. Concerted evolution of alpha satellite DNA: Evidence for species specificity and a general lack of sequence conservation among alphoid sequences of higher primates
61. A possible mechanism for the inhibition of ribosomal RNA gene transcription during mitosis
62. RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase 1 transcription factor which interacts with the polymerase independently of DNA template