-
1
-
-
0024916431
-
Recognition and elongation of telomeres by telomerase
-
Blackburn, E. H., Greider, C. W., Henderson, E., Lee, M. S., Shampay, J. and Shippen-Lentz, D. (1989) Recognition and elongation of telomeres by telomerase. Genome 31, 553-560.
-
(1989)
Genome
, vol.31
, pp. 553-560
-
-
Blackburn, E.H.1
Greider, C.W.2
Henderson, E.3
Lee, M.S.4
Shampay, J.5
Shippen-Lentz, D.6
-
2
-
-
34250841785
-
Replication and protection of telomeres
-
Verdun, R. E. and Karlseder, J. (2007) Replication and protection of telomeres. Nature 447, 924-931.
-
(2007)
Nature
, vol.447
, pp. 924-931
-
-
Verdun, R.E.1
Karlseder, J.2
-
3
-
-
39749163359
-
Telomerase and cancer therapeutics
-
Harley, C. B. (2008) Telomerase and cancer therapeutics. Nat. Rev. Cancer 8, 167-179.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 167-179
-
-
Harley, C.B.1
-
4
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
Jaskelioff, M., Muller, F. L., Paik, J. H., Thomas, E., Jiang, S., Adams, A. C., Sahin, E., Kost-Alimova, M., Protopopov, A., Cadinanos, J., Horner, J. W., Maratos-Flier, E. and Depinho, R. A. (2011) Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 469, 102-106.
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
Protopopov, A.9
Cadinanos, J.10
Horner, J.W.11
Maratos-Flier, E.12
Depinho, R.A.13
-
6
-
-
84870616090
-
Telomerase directly regulates NF-kappa B-dependent transcription
-
Ghosh, A., Saginc, G., Leow, S. C., Khattar, E., Shin, E. M., Yan, T. D., Wong, M., Zhang, Z. Z., Li, G. L., Sung, W. K., Zhou, J. B., Chng, W. J., Li, S., Liu, E. and Tergaonkar, V. (2012) Telomerase directly regulates NF-kappa B-dependent transcription. Nat. Cell Biol. 14, 1270-1281.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1270-1281
-
-
Ghosh, A.1
Saginc, G.2
Leow, S.C.3
Khattar, E.4
Shin, E.M.5
Yan, T.D.6
Wong, M.7
Zhang, Z.Z.8
Li, G.L.9
Sung, W.K.10
Zhou, J.B.11
Chng, W.J.12
Li, S.13
Liu, E.14
Tergaonkar, V.15
-
7
-
-
84887041006
-
Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NFkappaB-dependent transcription
-
Ding, D., Xi, P., Zhou, J., Wang, M. and Cong, Y. S. (2013) Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NFkappaB-dependent transcription. FASEB J. 27, 4375-4383.
-
(2013)
FASEB J.
, vol.27
, pp. 4375-4383
-
-
Ding, D.1
Xi, P.2
Zhou, J.3
Wang, M.4
Cong, Y.S.5
-
8
-
-
67650065306
-
Telomerase modulates Wnt signalling by association with target gene chromatin
-
Park, J. I., Venteicher, A. S., Hong, J. Y., Choi, J., Jun, S., Shkreli, M., Chang, W., Meng, Z., Cheung, P., Ji, H., McLaughlin, M., Veenstra, T. D., Nusse, R., McCrea, P. D. and Artandi, S. E. (2009) Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 460, 66-72.
-
(2009)
Nature
, vol.460
, pp. 66-72
-
-
Park, J.I.1
Venteicher, A.S.2
Hong, J.Y.3
Choi, J.4
Jun, S.5
Shkreli, M.6
Chang, W.7
Meng, Z.8
Cheung, P.9
Ji, H.10
McLaughlin, M.11
Veenstra, T.D.12
Nusse, R.13
McCrea, P.D.14
Artandi, S.E.15
-
9
-
-
38949156672
-
TERT promotes epithelial proliferation through transcriptional control of a Myc-and Wnt-related developmental program
-
Choi, J. K., Southworth, L. K., Sarin, K. Y., Venteicher, A. S., Ma, W. X., Chang, W., Cheung, P., Jun, S. H., Artandi, M. K., Shah, N., Kim, S. K. and Artandi, S. E. (2008) TERT promotes epithelial proliferation through transcriptional control of a Myc-and Wnt-related developmental program. Plos. Genet. 4, 0124-0138.
-
(2008)
Plos. Genet.
, vol.4
, pp. 0124-0138
-
-
Choi, J.K.1
Southworth, L.K.2
Sarin, K.Y.3
Venteicher, A.S.4
Ma, W.X.5
Chang, W.6
Cheung, P.7
Jun, S.H.8
Artandi, M.K.9
Shah, N.10
Kim, S.K.11
Artandi, S.E.12
-
10
-
-
84892558088
-
Endoplasmic reticulum stress activates telomerase
-
DOI: 10.1111/acel.12161.
-
Zhou, J., Mao, B., Zhou, Q., Ding, D., Wang, M., Guo, P., Gao, Y., Shay, J. W., Yuan, Z. and Cong, Y. S. (2013) Endoplasmic reticulum stress activates telomerase. Aging Cell DOI: 10.1111/acel.12161.
-
(2013)
Aging Cell
-
-
Zhou, J.1
Mao, B.2
Zhou, Q.3
Ding, D.4
Wang, M.5
Guo, P.6
Gao, Y.7
Shay, J.W.8
Yuan, Z.9
Cong, Y.S.10
-
11
-
-
0034122088
-
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function
-
Fu, W., Killen, M., Culmsee, C., Dhar, S., Pandita, T. K. and Mattson, M. P. (2000) The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function. J. Mol. Neurosci. 14, 3-15.
-
(2000)
J. Mol. Neurosci.
, vol.14
, pp. 3-15
-
-
Fu, W.1
Killen, M.2
Culmsee, C.3
Dhar, S.4
Pandita, T.K.5
Mattson, M.P.6
-
12
-
-
66349130192
-
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage
-
Haendeler, J., Drose, S., Buchner, N., Jakob, S., Altschmied, J., Goy, C., Spyridopoulos, I., Zeiher, A. M., Brandt, U. and Dimmeler, S. (2009) Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage. Arterioscler. Thromb. Vasc. Biol. 29, 929-935.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 929-935
-
-
Haendeler, J.1
Drose, S.2
Buchner, N.3
Jakob, S.4
Altschmied, J.5
Goy, C.6
Spyridopoulos, I.7
Zeiher, A.M.8
Brandt, U.9
Dimmeler, S.10
-
13
-
-
78651386195
-
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
-
Indran, I. R., Hande, M. P. and Pervaiz, S. (2011) hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells. Cancer Res. 71, 266-276.
-
(2011)
Cancer Res.
, vol.71
, pp. 266-276
-
-
Indran, I.R.1
Hande, M.P.2
Pervaiz, S.3
-
14
-
-
77953256244
-
A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction
-
Kovalenko, O. A., Caron, M. J., Ulema, P., Medrano, C., Thomas, A. P., Kimura, M., Bonini, M. G., Herbig, U. and Santos, J. H. (2010) A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction. Aging Cell 9, 203-219.
-
(2010)
Aging Cell
, vol.9
, pp. 203-219
-
-
Kovalenko, O.A.1
Caron, M.J.2
Ulema, P.3
Medrano, C.4
Thomas, A.P.5
Kimura, M.6
Bonini, M.G.7
Herbig, U.8
Santos, J.H.9
-
15
-
-
46749152214
-
Actions of human telomerase beyond telomeres
-
Cong, Y. and Shay, J. W. (2008) Actions of human telomerase beyond telomeres. Cell Res. 18, 725-732.
-
(2008)
Cell Res.
, vol.18
, pp. 725-732
-
-
Cong, Y.1
Shay, J.W.2
-
16
-
-
0038056347
-
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
-
Smith, L. L., Coller, H. A. and Roberts, J. M. (2003) Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat. Cell Biol. 5, 474-479.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 474-479
-
-
Smith, L.L.1
Coller, H.A.2
Roberts, J.M.3
-
17
-
-
0344837729
-
Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene
-
Lindvall, C., Hou, M., Komurasaki, T., Zheng, C., Henriksson, M., Sedivy, J. M., Bjorkholm, M., Teh, B. T., Nordenskjold, M. and Xu, D. (2003) Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene. Cancer Res. 63, 1743-1747.
-
(2003)
Cancer Res.
, vol.63
, pp. 1743-1747
-
-
Lindvall, C.1
Hou, M.2
Komurasaki, T.3
Zheng, C.4
Henriksson, M.5
Sedivy, J.M.6
Bjorkholm, M.7
Teh, B.T.8
Nordenskjold, M.9
Xu, D.10
-
18
-
-
33846631835
-
Up-regulation of Mac-2 binding protein by hTERT in gastric cancer
-
Park, Y. P., Choi, S. C., Kim, J. H., Song, E. Y., Kim, J. W., Yoon, D. Y., Yeom, Y. I., Lim, J. S., Paik, S. G. and Lee, H. G. (2007) Up-regulation of Mac-2 binding protein by hTERT in gastric cancer. Int. J. Cancer 120, 813-820.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 813-820
-
-
Park, Y.P.1
Choi, S.C.2
Kim, J.H.3
Song, E.Y.4
Kim, J.W.5
Yoon, D.Y.6
Yeom, Y.I.7
Lim, J.S.8
Paik, S.G.9
Lee, H.G.10
-
19
-
-
33746190649
-
Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1
-
Jagadeesh, S. and Banerjee, P. P. (2006) Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1. Biochem. Biophys. Res. Commun. 347, 774-780.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.347
, pp. 774-780
-
-
Jagadeesh, S.1
Banerjee, P.P.2
-
20
-
-
23944526322
-
Global gene expression response to telomerase in bovine adrenocortical cells
-
Perrault, S. D., Hornsby, P. J. and Betts, D. H. (2005) Global gene expression response to telomerase in bovine adrenocortical cells. Biochem. Biophys. Res. Commun. 335, 925-936.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.335
, pp. 925-936
-
-
Perrault, S.D.1
Hornsby, P.J.2
Betts, D.H.3
-
21
-
-
0038504020
-
Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I
-
Young, J. I., Sedivy, J. M. and Smith, J. R. (2003) Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I. J. Biol. Chem. 278, 19904-19908.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19904-19908
-
-
Young, J.I.1
Sedivy, J.M.2
Smith, J.R.3
-
22
-
-
20444371017
-
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
-
U. S. A.
-
Masutomi, K., Possemato, R., Wong, J. M., Currier, J. L., Tothova, Z., Manola, J. B., Ganesan, S., Lansdorp, P. M., Collins, K. and Hahn, W. C. (2005) The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc. Natl. Acad. Sci. U. S. A. 102, 8222-8227.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 8222-8227
-
-
Masutomi, K.1
Possemato, R.2
Wong, J.M.3
Currier, J.L.4
Tothova, Z.5
Manola, J.B.6
Ganesan, S.7
Lansdorp, P.M.8
Collins, K.9
Hahn, W.C.10
-
23
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. and Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
24
-
-
18644373013
-
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism
-
U. S. A.
-
Stewart, S. A., Hahn, W. C., O'Connor, B. F., Banner, E. N., Lundberg, A. S., Modha, P., Mizuno, H., Brooks, M. W., Fleming, M., Zimonjic, D. B., Popescu, N. C. and Weinberg, R. A. (2002) Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proc. Natl. Acad. Sci. U. S. A. 99, 12606-12611.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 12606-12611
-
-
Stewart, S.A.1
Hahn, W.C.2
O'Connor, B.F.3
Banner, E.N.4
Lundberg, A.S.5
Modha, P.6
Mizuno, H.7
Brooks, M.W.8
Fleming, M.9
Zimonjic, D.B.10
Popescu, N.C.11
Weinberg, R.A.12
-
25
-
-
84856213846
-
The diverse and complex roles of NF-kappaB subunits in cancer
-
Perkins, N. D. (2012) The diverse and complex roles of NF-kappaB subunits in cancer. Nat. Rev. Cancer 12, 121-132.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 121-132
-
-
Perkins, N.D.1
-
26
-
-
80051987703
-
Crosstalk in NF-kappaB signaling pathways
-
Oeckinghaus, A., Hayden, M. S. and Ghosh, S. (2011) Crosstalk in NF-kappaB signaling pathways. Nat. Immunol. 12, 695-708.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 695-708
-
-
Oeckinghaus, A.1
Hayden, M.S.2
Ghosh, S.3
-
27
-
-
0034711223
-
NF-kappa B regulates transcription of the mouse telomerase catalytic subunit
-
Yin, L., Hubbard, A. K. and Giardina, C. (2000) NF-kappa B regulates transcription of the mouse telomerase catalytic subunit. J. Biol. Chem. 275, 36671-36675.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36671-36675
-
-
Yin, L.1
Hubbard, A.K.2
Giardina, C.3
-
28
-
-
0036645153
-
Cytokines modulate telomerase activity in a human multiple myeloma cell line
-
Akiyama, M., Hideshima, T., Hayashi, T., Tai, Y. T., Mitsiades, C. S., Mitsiades, N., Chauhan, D., Richardson, P., Munshi, N. C. and Anderson, K. C. (2002) Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res. 62, 3876-3882.
-
(2002)
Cancer Res.
, vol.62
, pp. 3876-3882
-
-
Akiyama, M.1
Hideshima, T.2
Hayashi, T.3
Tai, Y.T.4
Mitsiades, C.S.5
Mitsiades, N.6
Chauhan, D.7
Richardson, P.8
Munshi, N.C.9
Anderson, K.C.10
-
29
-
-
81255157509
-
NF-kappaB p65 modulates the telomerase reverse transcriptase in the HepG(2) hepatoma cell line
-
Zuo, Q. P., Liu, S. K., Li, Z. J., Li, B., Zhou, Y. L., Guo, R. and Huang, L. H. (2011) NF-kappaB p65 modulates the telomerase reverse transcriptase in the HepG(2) hepatoma cell line. Eur. J. Pharmacol. 672, 113-120.
-
(2011)
Eur. J. Pharmacol.
, vol.672
, pp. 113-120
-
-
Zuo, Q.P.1
Liu, S.K.2
Li, Z.J.3
Li, B.4
Zhou, Y.L.5
Guo, R.6
Huang, L.H.7
-
30
-
-
84870616090
-
Telomerase directly regulates NF-kappaB-dependent transcription
-
Ghosh, A., Saginc, G., Leow, S. C., Khattar, E., Shin, E. M., Yan, T. D., Wong, M., Zhang, Z., Li, G., Sung, W. K., Zhou, J., Chng, W. J., Li, S., Liu, E. and Tergaonkar, V. (2012) Telomerase directly regulates NF-kappaB-dependent transcription. Nat. Cell Biol. 14, 1270-1281.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1270-1281
-
-
Ghosh, A.1
Saginc, G.2
Leow, S.C.3
Khattar, E.4
Shin, E.M.5
Yan, T.D.6
Wong, M.7
Zhang, Z.8
Li, G.9
Sung, W.K.10
Zhou, J.11
Chng, W.J.12
Li, S.13
Liu, E.14
Tergaonkar, V.15
-
31
-
-
84866153511
-
Connection between telomerase activity in PBMC and markers of inflammation and endothelial dysfunction in patients with metabolic syndrome
-
Rentoukas, E., Tsarouhas, K., Kaplanis, I., Korou, E., Nikolaou, M., Marathonitis, G., Kokkinou, S., Haliassos, A., Mamalaki, A., Kouretas, D. and Tsitsimpikou, C. (2012) Connection between telomerase activity in PBMC and markers of inflammation and endothelial dysfunction in patients with metabolic syndrome. PLoS One. 7, e35739.
-
(2012)
PLoS One
, vol.7
-
-
Rentoukas, E.1
Tsarouhas, K.2
Kaplanis, I.3
Korou, E.4
Nikolaou, M.5
Marathonitis, G.6
Kokkinou, S.7
Haliassos, A.8
Mamalaki, A.9
Kouretas, D.10
Tsitsimpikou, C.11
-
32
-
-
79551486264
-
Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages
-
Gizard, F., Heywood, E. B., Findeisen, H. M., Zhao, Y., Jones, K. L., Cudejko, C., Post, G. R., Staels, B. and Bruemmer, D. (2011) Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages. Arterioscler. Thromb. Vasc. Biol. 31, 245-252.
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 245-252
-
-
Gizard, F.1
Heywood, E.B.2
Findeisen, H.M.3
Zhao, Y.4
Jones, K.L.5
Cudejko, C.6
Post, G.R.7
Staels, B.8
Bruemmer, D.9
-
33
-
-
67650601775
-
Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity
-
Zhou, L., Zheng, D., Wang, M. and Cong, Y. S. (2009) Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity. Biochem. Biophys. Res. Commun. 386, 739-743.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.386
, pp. 739-743
-
-
Zhou, L.1
Zheng, D.2
Wang, M.3
Cong, Y.S.4
-
34
-
-
84883743387
-
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells
-
Liu, Z., Li, Q., Li, K., Chen, L., Li, W., Hou, M., Liu, T., Yang, J., Lindvall, C., Bjorkholm, M., Jia, J. and Xu, D. (2013) Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene 32, 4203-4213.
-
(2013)
Oncogene
, vol.32
, pp. 4203-4213
-
-
Liu, Z.1
Li, Q.2
Li, K.3
Chen, L.4
Li, W.5
Hou, M.6
Liu, T.7
Yang, J.8
Lindvall, C.9
Bjorkholm, M.10
Jia, J.11
Xu, D.12
-
35
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas, J. N. and Moon, R. T. (2013) WNT signalling pathways as therapeutic targets in cancer. Nat. Rev. Cancer 13, 11-26.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
36
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J., von Kries, J. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R. and Birchmeier, W. (1996) Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382, 638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
37
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. (2006) Wnt/beta-catenin signaling in development and disease. Cell 127, 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
38
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
Sarin, K. Y., Cheung, P., Gilison, D., Lee, E., Tennen, R. I., Wang, E., Artandi, M. K., Oro, A. E. and Artandi, S. E. (2005) Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436, 1048-1052.
-
(2005)
Nature
, vol.436
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
Lee, E.4
Tennen, R.I.5
Wang, E.6
Artandi, M.K.7
Oro, A.E.8
Artandi, S.E.9
-
39
-
-
23844540299
-
Effects of telomerase and telomere length on epidermal stem cell behavior
-
Flores, I., Cayuela, M. L. and Blasco, M. A. (2005) Effects of telomerase and telomere length on epidermal stem cell behavior. Science 309, 1253-1256.
-
(2005)
Science
, vol.309
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
40
-
-
84855493321
-
Maintenance of tumor initiating cells of defined genetic composition by nucleostemin
-
U. S. A.
-
Okamoto, N., Yasukawa, M., Nguyen, C., Kasim, V., Maida, Y., Possemato, R., Shibata, T., Ligon, K. L., Fukami, K., Hahn, W. C. and Masutomi, K. (2011) Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. Proc. Natl. Acad. Sci. U. S. A. 108, 20388-20393.
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 20388-20393
-
-
Okamoto, N.1
Yasukawa, M.2
Nguyen, C.3
Kasim, V.4
Maida, Y.5
Possemato, R.6
Shibata, T.7
Ligon, K.L.8
Fukami, K.9
Hahn, W.C.10
Masutomi, K.11
-
41
-
-
33746651038
-
STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
-
Zhang, Q., Wang, H. Y., Woetmann, A., Raghunath, P. N., Odum, N. and Wasik, M. A. (2006) STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes. Blood 108, 1058-1064.
-
(2006)
Blood
, vol.108
, pp. 1058-1064
-
-
Zhang, Q.1
Wang, H.Y.2
Woetmann, A.3
Raghunath, P.N.4
Odum, N.5
Wasik, M.A.6
-
42
-
-
0030447148
-
In vitro activation of Stat3 by epidermal growth factor receptor kinase
-
U. S. A.
-
Park, O. K., Schaefer, T. S. and Nathans, D. (1996) In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc. Natl. Acad. Sci. U. S. A. 93, 13704-13708.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 13704-13708
-
-
Park, O.K.1
Schaefer, T.S.2
Nathans, D.3
-
43
-
-
79958053622
-
Phenotypes in mTERT(+)/(-) and mTERT(-)/(-) mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase
-
Strong, M. A., Vidal-Cardenas, S. L., Karim, B., Yu, H., Guo, N. and Greider, C. W. (2011) Phenotypes in mTERT(+)/(-) and mTERT(-)/(-) mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase. Mol. Cell. Biol. 31, 2369-2379.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 2369-2379
-
-
Strong, M.A.1
Vidal-Cardenas, S.L.2
Karim, B.3
Yu, H.4
Guo, N.5
Greider, C.W.6
-
44
-
-
84891427530
-
An investigation of the effects of the telomerase core protein TERT on Wnt signaling in human breast cancer cells
-
DOI: 10.1128/MCB.00844-13.
-
Listerman, I., Gazzaniga, F. S. and Blackburn, E. H. (2013) An investigation of the effects of the telomerase core protein TERT on Wnt signaling in human breast cancer cells. Mol. Cell. Biol. DOI: 10.1128/MCB.00844-13.
-
(2013)
Mol. Cell. Biol.
-
-
Listerman, I.1
Gazzaniga, F.S.2
Blackburn, E.H.3
-
45
-
-
84879978463
-
Implications of telomere-independent activities of telomerase reverse transcriptase in human cancer
-
Ding, D., Zhou, J., Wang, M. and Cong, Y. S. (2013) Implications of telomere-independent activities of telomerase reverse transcriptase in human cancer. FEBS. J. 280, 3205-3211.
-
(2013)
FEBS. J.
, vol.280
, pp. 3205-3211
-
-
Ding, D.1
Zhou, J.2
Wang, M.3
Cong, Y.S.4
-
46
-
-
84862617605
-
Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells
-
Hoffmeyer, K., Raggioli, A., Rudloff, S., Anton, R., Hierholzer, A., Del Valle, I., Hein, K., Vogt, R. and Kemler, R. (2012) Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells. Science 336, 1549-1554.
-
(2012)
Science
, vol.336
, pp. 1549-1554
-
-
Hoffmeyer, K.1
Raggioli, A.2
Rudloff, S.3
Anton, R.4
Hierholzer, A.5
Del Valle, I.6
Hein, K.7
Vogt, R.8
Kemler, R.9
-
47
-
-
70249114371
-
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA
-
Maida, Y., Yasukawa, M., Furuuchi, M., Lassmann, T., Possemato, R., Okamoto, N., Kasim, V., Hayashizaki, Y., Hahn, W. C. and Masutomi, K. (2009) An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Nature 461, 230-235.
-
(2009)
Nature
, vol.461
, pp. 230-235
-
-
Maida, Y.1
Yasukawa, M.2
Furuuchi, M.3
Lassmann, T.4
Possemato, R.5
Okamoto, N.6
Kasim, V.7
Hayashizaki, Y.8
Hahn, W.C.9
Masutomi, K.10
-
48
-
-
17744393618
-
Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia
-
Ridanpaa, M., van Eenennaam, H., Pelin, K., Chadwick, R., Johnson, C., Yuan, B., vanVenrooij, W., Pruijn, G., Salmela, R., Rockas, S., Makitie, O., Kaitila, I. and de la Chapelle, A. (2001) Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia. Cell 104, 195-203.
-
(2001)
Cell
, vol.104
, pp. 195-203
-
-
Ridanpaa, M.1
van Eenennaam, H.2
Pelin, K.3
Chadwick, R.4
Johnson, C.5
Yuan, B.6
vanVenrooij, W.7
Pruijn, G.8
Salmela, R.9
Rockas, S.10
Makitie, O.11
Kaitila, I.12
de la Chapelle, A.13
-
49
-
-
0023152084
-
A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA
-
Chang, D. D. and Clayton, D. A. (1987) A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA. Science 235, 1178-1184.
-
(1987)
Science
, vol.235
, pp. 1178-1184
-
-
Chang, D.D.1
Clayton, D.A.2
-
50
-
-
80054781000
-
RMRP is a non-coding RNA essential for early murine development
-
Rosenbluh, J., Nijhawan, D., Chen, Z., Wong, K. K., Masutomi, K. and Hahn, W. C. (2011) RMRP is a non-coding RNA essential for early murine development. PLoS One 6, e26270.
-
(2011)
PLoS One
, vol.6
-
-
Rosenbluh, J.1
Nijhawan, D.2
Chen, Z.3
Wong, K.K.4
Masutomi, K.5
Hahn, W.C.6
-
51
-
-
84855905939
-
Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria
-
Sharma, N. K., Reyes, A., Green, P., Caron, M. J., Bonini, M. G., Gordon, D. M., Holt, I. J. and Santos, J. H. (2012) Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria. Nucleic Acids Res. 40, 712-725.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 712-725
-
-
Sharma, N.K.1
Reyes, A.2
Green, P.3
Caron, M.J.4
Bonini, M.G.5
Gordon, D.M.6
Holt, I.J.7
Santos, J.H.8
-
52
-
-
66349130192
-
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage
-
Haendeler, J., Drose, S., Buchner, N., Jakob, S., Altschmied, J., Goy, C., Spyridopoulos, I., Zeiher, A. M., Brandt, U. and Dimmeler, S. (2009) Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage. Arterioscler. Thromb. Vasc. Biol. 29, 929-935.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 929-935
-
-
Haendeler, J.1
Drose, S.2
Buchner, N.3
Jakob, S.4
Altschmied, J.5
Goy, C.6
Spyridopoulos, I.7
Zeiher, A.M.8
Brandt, U.9
Dimmeler, S.10
-
53
-
-
78651386195
-
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function and inhibits ROS-mediated apoptosis in cancer cells
-
Indran, I. R., Hande, M. P. and Pervaiz, S. (2011) hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function and inhibits ROS-mediated apoptosis in cancer cells. Cancer Res. 71, 266-276.
-
(2011)
Cancer Res.
, vol.71
, pp. 266-276
-
-
Indran, I.R.1
Hande, M.P.2
Pervaiz, S.3
-
54
-
-
33746851957
-
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway
-
Massard, C., Zermati, Y., Pauleau, A. L., Larochette, N., Metivier, D., Sabatier, L., Kroemer, G. and Soria, J. C. (2006) hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway. Oncogene 25, 4505-4514.
-
(2006)
Oncogene
, vol.25
, pp. 4505-4514
-
-
Massard, C.1
Zermati, Y.2
Pauleau, A.L.3
Larochette, N.4
Metivier, D.5
Sabatier, L.6
Kroemer, G.7
Soria, J.C.8
-
55
-
-
77649178739
-
Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase
-
Indran, I. R., Hande, M. P. and Pervaiz, S. (2010) Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase. Mol. Aspects. Med. 31, 21-28.
-
(2010)
Mol. Aspects. Med.
, vol.31
, pp. 21-28
-
-
Indran, I.R.1
Hande, M.P.2
Pervaiz, S.3
-
56
-
-
33746591648
-
Genes and pathways downstream of telomerase in melanoma metastasis
-
U. S. A.
-
Bagheri, S., Nosrati, M., Li, S., Fong, S., Torabian, S., Rangel, J., Moore, D. H., Federman, S., Laposa, R. R., Baehner, F. L., Sagebiel, R. W., Cleaver, J. E., Haqq, C., Debs, R. J., Blackburn, E. H. and Kashani-Sabet, M. (2006) Genes and pathways downstream of telomerase in melanoma metastasis. Proc. Natl. Acad. Sci. U. S. A. 103, 11306-11311.
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 11306-11311
-
-
Bagheri, S.1
Nosrati, M.2
Li, S.3
Fong, S.4
Torabian, S.5
Rangel, J.6
Moore, D.H.7
Federman, S.8
Laposa, R.R.9
Baehner, F.L.10
Sagebiel, R.W.11
Cleaver, J.E.12
Haqq, C.13
Debs, R.J.14
Blackburn, E.H.15
Kashani-Sabet, M.16
-
57
-
-
21244502260
-
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
-
Li, S., Crothers, J., Haqq, C. M. and Blackburn, E. H. (2005) Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. J. Biol. Chem. 280, 23709-23717.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23709-23717
-
-
Li, S.1
Crothers, J.2
Haqq, C.M.3
Blackburn, E.H.4
|