메뉴 건너뛰기




Volumn 141, Issue 2, 2014, Pages 137-152

Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase

Author keywords

Cajal body; Dense fibrillar component of nucleolus; hTERT; TCAB1; Telomerase holoenzyme assembly; Telomere

Indexed keywords

CELL LINE, TUMOR; CELL NUCLEOLUS; FLOW CYTOMETRY; HOLOENZYMES; HUMANS; S PHASE; TELOMERASE;

EID: 84893864827     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-013-1166-x     Document Type: Article
Times cited : (42)

References (53)
  • 1
    • 67650079362 scopus 로고    scopus 로고
    • Syndromes of telomere shortening
    • 1:CAS:528:DC%2BD1MXht12qsrrE 2818564 19405848 10.1146/annurev-genom- 082908-150046
    • Armanios M (2009) Syndromes of telomere shortening. Annu Rev Genomics Hum Genet 10:45-61
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 45-61
    • Armanios, M.1
  • 2
    • 33745849998 scopus 로고    scopus 로고
    • The structure and function of telomerase reverse transcriptase
    • DOI 10.1146/annurev.biochem.75.103004.142412
    • Autexier C, Lue NF (2006) The structure and function of telomerase reverse transcriptase. Annu Rev Biochem 75:493-517 (Pubitemid 44118041)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 493-517
    • Autexier, C.1    Lue, N.F.2
  • 4
    • 47549086947 scopus 로고    scopus 로고
    • How Telomerase Reaches Its End: Mechanism of Telomerase Regulation by the Telomeric Complex
    • DOI 10.1016/j.molcel.2008.06.013, PII S1097276508004310
    • Bianchi A, Shore D (2008) How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex. Mol Cell 31:153-165 (Pubitemid 352005819)
    • (2008) Molecular Cell , vol.31 , Issue.2 , pp. 153-165
    • Bianchi, A.1    Shore, D.2
  • 5
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • DOI 10.1016/S0092-8674(01)00492-5
    • Blackburn EH (2001) Switching and signaling at the telomere. Cell 106:661-673 (Pubitemid 32900658)
    • (2001) Cell , vol.106 , Issue.6 , pp. 661-673
    • Blackburn, E.H.1
  • 6
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • DOI 10.1016/S0092-8674(01)80006-4
    • Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91:25-34 (Pubitemid 27431310)
    • (1997) Cell , vol.91 , Issue.1 , pp. 25-34
    • Blasco, M.A.1    Lee, H.-W.2    Hande, M.P.3    Samper, E.4    Lansdorp, P.M.5    DePinho, R.A.6    Greider, C.W.7
  • 8
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR (1997) Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3:1271-1274 (Pubitemid 27508830)
    • (1997) Nature Medicine , vol.3 , Issue.11 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 9
    • 0034598919 scopus 로고    scopus 로고
    • Secondary structure of vertebrate telomerase RNA
    • 1:CAS:528:DC%2BD3cXhvVeqtbc%3D 10721988 10.1016/S0092-8674(00)80687-X
    • Chen JL, Blasco MA, Greider CW (2000) Secondary structure of vertebrate telomerase RNA. Cell 100:503-514
    • (2000) Cell , vol.100 , pp. 503-514
    • Chen, J.L.1    Blasco, M.A.2    Greider, C.W.3
  • 10
    • 38849191137 scopus 로고    scopus 로고
    • Physiological assembly and activity of human telomerase complexes
    • DOI 10.1016/j.mad.2007.10.008, PII S0047637407001698
    • Collins K (2008) Physiological assembly and activity of human telomerase complexes. Mech Ageing Dev 129:91-98 (Pubitemid 351199863)
    • (2008) Mechanisms of Ageing and Development , vol.129 , Issue.1-2 , pp. 91-98
    • Collins, K.1
  • 11
    • 34748876539 scopus 로고    scopus 로고
    • Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation
    • DOI 10.1016/j.molcel.2007.07.020, PII S1097276507004935
    • Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns RM, Terns MP, Lingner J (2007) Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell 27:882-889 (Pubitemid 47488182)
    • (2007) Molecular Cell , vol.27 , Issue.6 , pp. 882-889
    • Cristofari, G.1    Adolf, E.2    Reichenbach, P.3    Sikora, K.4    Terns, R.M.5    Terns, M.P.6    Lingner, J.7
  • 12
    • 33646076438 scopus 로고    scopus 로고
    • Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells
    • 1:CAS:528:DC%2BD28XktVCgu7o%3D 16618814 10.1083/jcb.200601105
    • Darzacq X, Kittur N, Roy S, Shav-Tal Y, Singer RH, Meier UT (2006) Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol 173:207-218
    • (2006) J Cell Biol , vol.173 , pp. 207-218
    • Darzacq, X.1    Kittur, N.2    Roy, S.3    Shav-Tal, Y.4    Singer, R.H.5    Meier, U.T.6
  • 13
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • DOI 10.1101/gad.1346005
    • de Lange T (2005) Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 19:2100-2110 (Pubitemid 41330312)
    • (2005) Genes and Development , vol.19 , Issue.18 , pp. 2100-2110
    • De Lange, T.1
  • 14
    • 0033672470 scopus 로고    scopus 로고
    • Telomere maintenance by recombination in human cells
    • 1:CAS:528:DC%2BD3cXptVWgtrs%3D 11101843 10.1038/82586
    • Dunham MA, Neumann AA, Fasching CL, Reddel RR (2000) Telomere maintenance by recombination in human cells. Nat Genet 26:447-450
    • (2000) Nat Genet , vol.26 , pp. 447-450
    • Dunham, M.A.1    Neumann, A.A.2    Fasching, C.L.3    Reddel, R.R.4
  • 15
    • 77952604818 scopus 로고    scopus 로고
    • Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo
    • 1:CAS:528:DC%2BC3cXnsFKgsrc%3D 2876521 20351177 10.1128/MCB.00151-10
    • Egan ED, Collins K (2010) Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo. Mol Cell Biol 30:2775-2786
    • (2010) Mol Cell Biol , vol.30 , pp. 2775-2786
    • Egan, E.D.1    Collins, K.2
  • 16
    • 84866611481 scopus 로고    scopus 로고
    • Biogenesis of telomerase ribonucleoproteins
    • 1:CAS:528:DC%2BC38XhsVent73I 22875809 10.1261/rna.034629.112
    • Egan ED, Collins K (2012) Biogenesis of telomerase ribonucleoproteins. RNA 18:1747-1759
    • (2012) RNA , vol.18 , pp. 1747-1759
    • Egan, E.D.1    Collins, K.2
  • 17
    • 0038392866 scopus 로고    scopus 로고
    • Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs
    • DOI 10.1016/S1097-2765(03)00196-5
    • Fu D, Collins K (2003) Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs. Mol Cell 11:1361-1372 (Pubitemid 36645153)
    • (2003) Molecular Cell , vol.11 , Issue.5 , pp. 1361-1372
    • Fu, D.1    Collins, K.2
  • 19
    • 17944388104 scopus 로고    scopus 로고
    • Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal
    • DOI 10.1083/jcb.200310138
    • Jády BE, Bertrand E, Kiss T (2004) Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. J Cell Biol 164:647-652 (Pubitemid 38282948)
    • (2004) Journal of Cell Biology , vol.164 , Issue.5 , pp. 647-652
    • Jady, B.E.1    Bertrand, E.2    Kiss, T.3
  • 20
    • 31944436260 scopus 로고    scopus 로고
    • Cell cycle-dependent recruitment of telomerase RNA and cajal bodies to human telomeres
    • DOI 10.1091/mbc.E05-09-0904
    • Jády BE, Richard P, Bertrand E, Kiss T (2006) Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres. Mol Biol Cell 17:944-954 (Pubitemid 43191126)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.2 , pp. 944-954
    • Jady, B.E.1    Richard, P.2    Bertrand, E.3    Kiss, T.4
  • 22
    • 0030743347 scopus 로고    scopus 로고
    • Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
    • DOI 10.1093/nar/25.13.2595
    • Kim NW, Wu F (1997) Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). Nucleic Acids Res 25:2595-2597 (Pubitemid 27298154)
    • (1997) Nucleic Acids Research , vol.25 , Issue.13 , pp. 2595-2597
    • Kim, N.W.1    Wu, F.2
  • 24
    • 0038069024 scopus 로고    scopus 로고
    • Potent inhibition of human telomerase by nitrostyrene derivatives
    • DOI 10.1124/mol.63.5.1117
    • Kim JH, Kim JH, Lee GE, Lee JE, Chung IK (2003) Potent inhibition of human telomerase by nitrostyrene derivatives. Mol Pharmacol 63:1117-1124 (Pubitemid 36529930)
    • (2003) Molecular Pharmacology , vol.63 , Issue.5 , pp. 1117-1124
    • Kim, J.H.1    Kim, J.H.2    Lee, G.E.3    Lee, J.E.4    Chung, I.K.5
  • 25
    • 77749329940 scopus 로고    scopus 로고
    • Box H/ACA small ribonucleoproteins
    • 20227365 10.1016/j.molcel.2010.01.032
    • Kiss T, Fayet-Lebaron E, Jády BE (2010) Box H/ACA small ribonucleoproteins. Mol Cell 37:597-606
    • (2010) Mol Cell , vol.37 , pp. 597-606
    • Kiss, T.1    Fayet-Lebaron, E.2    Jády, B.E.3
  • 26
    • 0035144580 scopus 로고    scopus 로고
    • RNA binding domain of telomerase reverse transcriptase
    • DOI 10.1128/MCB.21.4.990-1000.2001
    • Lai CK, Mitchell JR, Collins K (2001) RNA binding domain of telomerase reverse transcriptase. Mol Cell Biol 21:990-1000 (Pubitemid 32114949)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.4 , pp. 990-1000
    • Lai, C.K.1    Mitchell, J.R.2    Collins, K.3
  • 27
    • 4544379480 scopus 로고    scopus 로고
    • DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase
    • DOI 10.1074/jbc.M401843200
    • Lee GE, Yu EY, Cho CH, Lee J, Muller MT, Chung IK (2004) DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase. J Biol Chem 279:34750-34755 (Pubitemid 39318106)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34750-34755
    • Gun, E.L.1    Eun, Y.Y.2    Chae, H.C.3    Lee, J.4    Muller, M.T.5    In, K.C.6
  • 28
    • 78650632231 scopus 로고    scopus 로고
    • CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity
    • 1:CAS:528:DC%2BC3cXhs1WisrzJ 20959453 10.1074/jbc.M110.149831
    • Lee JH, Khadka P, Baek SH, Chung IK (2010) CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity. J Biol Chem 285:42033-42045
    • (2010) J Biol Chem , vol.285 , pp. 42033-42045
    • Lee, J.H.1    Khadka, P.2    Baek, S.H.3    Chung, I.K.4
  • 29
    • 0029128798 scopus 로고
    • Telomerase and DNA end replication: No longer a lagging strand problem?
    • 1:CAS:528:DyaK2MXotVOgsb8%3D 7545310 10.1126/science.7545310
    • Lingner J, Cooper JP, Cech TR (1995) Telomerase and DNA end replication: no longer a lagging strand problem? Science 269:1533-1534
    • (1995) Science , vol.269 , pp. 1533-1534
    • Lingner, J.1    Cooper, J.P.2    Cech, T.R.3
  • 30
    • 10944240539 scopus 로고    scopus 로고
    • Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins
    • DOI 10.1074/jbc.M409293200
    • Liu D, O'Connor MS, Qin J, Songyang Z (2004) Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. J Biol Chem 279:51338-51342 (Pubitemid 40017880)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 51338-51342
    • Liu, D.1    O'Connor, M.S.2    Qin, J.3    Songyang, Z.4
  • 31
    • 0034175814 scopus 로고    scopus 로고
    • Cell cycle restriction of telomere elongation
    • DOI 10.1016/S0960-9822(00)00450-4
    • Marcand S, Brevet V, Mann C, Gilson E (2000) Cell cycle restriction of telomere elongation. Curr Biol 10:487-490 (Pubitemid 30247340)
    • (2000) Current Biology , vol.10 , Issue.8 , pp. 487-490
    • Marcand, S.1    Brevet, V.2    Mann, C.3    Gilson, E.4
  • 32
    • 0033636897 scopus 로고    scopus 로고
    • Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase in vivo and in vitro
    • 1:CAS:528:DC%2BD3cXmsFWmsbY%3D 10983983 10.1016/S1097-2765(00)00036-8
    • Mitchell JR, Collins K (2000) Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase in vivo and in vitro. Mol Cell 6:361-371
    • (2000) Mol Cell , vol.6 , pp. 361-371
    • Mitchell, J.R.1    Collins, K.2
  • 33
    • 0032961170 scopus 로고    scopus 로고
    • A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end
    • Mitchell JR, Cheng J, Collins K (1999) A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 39 end. Mol Cell Biol 19:567-576 (Pubitemid 29018458)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.1 , pp. 567-576
    • Mitchell, J.R.1    Cheng, J.2    Collins, K.3
  • 34
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • 1:CAS:528:DC%2BD1cXhsFemtbrI 18680434 10.1146/annurev.genet.41.110306. 130350
    • Palm W, de Lange T (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42:301-334
    • (2008) Annu Rev Genet , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 35
    • 33645296102 scopus 로고    scopus 로고
    • Cotranscriptional recognition of human intronic box H/ACA snoRNAs occurs in a splicing-independent manner
    • 1:CAS:528:DC%2BD28XivFSrsbw%3D 1430331 16537900 10.1128/MCB.26.7.2540- 2549.2006
    • Richard P, Kiss AM, Darzacq X, Kiss T (2006) Cotranscriptional recognition of human intronic box H/ACA snoRNAs occurs in a splicing-independent manner. Mol Cell Biol 26:2540-2549
    • (2006) Mol Cell Biol , vol.26 , pp. 2540-2549
    • Richard, P.1    Kiss, A.M.2    Darzacq, X.3    Kiss, T.4
  • 36
    • 79955492603 scopus 로고    scopus 로고
    • Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation
    • 1:CAS:528:DC%2BC3MXlvVyiurk%3D 3097130 21514196 10.1016/j.molcel.2011.03. 012
    • Robart AR, Collins K (2011) Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation. Mol Cell 42:308-318
    • (2011) Mol Cell , vol.42 , pp. 308-318
    • Robart, A.R.1    Collins, K.2
  • 37
    • 0018082456 scopus 로고
    • Ultrastructural localization of intracellular antigens by the use of protein A-gold complex
    • Roth J, Bendayan M, Orci L (1978) Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem 26:1074-1081 (Pubitemid 9076936)
    • (1978) Journal of Histochemistry and Cytochemistry , vol.26 , Issue.12 , pp. 1074-1081
    • Roth, J.1    Bendayan, M.2    Orci, L.3
  • 38
    • 78650639126 scopus 로고    scopus 로고
    • The genetics and clinical manifestations of telomere biology disorders
    • 21189492 10.1097/GIM.0b013e3181f415b5
    • Savage SA, Bertuch AA (2010) The genetics and clinical manifestations of telomere biology disorders. Genet Med 12:753-764
    • (2010) Genet Med , vol.12 , pp. 753-764
    • Savage, S.A.1    Bertuch, A.A.2
  • 39
    • 84867243004 scopus 로고    scopus 로고
    • Specificity requirements for human telomere protein interaction with telomerase holoenzyme
    • 1:CAS:528:DC%2BC38XhsVKlsb3O 22893708 10.1074/jbc.M112.394767
    • Sexton AN, Youmans DT, Collins K (2012) Specificity requirements for human telomere protein interaction with telomerase holoenzyme. J Biol Chem 287:34455-34464
    • (2012) J Biol Chem , vol.287 , pp. 34455-34464
    • Sexton, A.N.1    Youmans, D.T.2    Collins, K.3
  • 40
    • 84860456242 scopus 로고    scopus 로고
    • Removal of shelterin reveals the telomere end-protection problem
    • 1:CAS:528:DC%2BC38Xmt1GnsbY%3D 3477646 22556254 10.1126/science.1218498
    • Sfeir A, de Lange T (2012) Removal of shelterin reveals the telomere end-protection problem. Science 336:593-597
    • (2012) Science , vol.336 , pp. 593-597
    • Sfeir, A.1    De Lange, T.2
  • 41
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • DOI 10.1146/annurev.biochem.73.071403.160049
    • Smogorzewska A, de Lange T (2004) Regulation of telomerase by telomeric proteins. Annu Rev Biochem 73:177-208 (Pubitemid 39050367)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 42
    • 84864020175 scopus 로고    scopus 로고
    • Telomerase recruitment requires both TCAB1 and Cajal bodies independently
    • 1:CAS:528:DC%2BC38XpsVyks74%3D 3434490 22547674 10.1128/MCB.00379-12
    • Stern JL, Zyner KG, Pickett HA, Cohen SB, Bryan TM (2012) Telomerase recruitment requires both TCAB1 and Cajal bodies independently. Mol Cell Biol 32:2384-2395
    • (2012) Mol Cell Biol , vol.32 , pp. 2384-2395
    • Stern, J.L.1    Zyner, K.G.2    Pickett, H.A.3    Cohen, S.B.4    Bryan, T.M.5
  • 44
    • 55549090746 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase is required for the localization of telomerase RNA to Cajal bodies and telomeres in human cancer cells
    • 1:CAS:528:DC%2BD1cXhtFKntLzF 2526684 18562689 10.1091/mbc.E08-02-0184
    • Tomlinson RL, Abreu EB, Ziegler T, Ly H, Counter CM, Terns RM, Terns MP (2008) Telomerase reverse transcriptase is required for the localization of telomerase RNA to Cajal bodies and telomeres in human cancer cells. Mol Biol Cell 19:3793-3800
    • (2008) Mol Biol Cell , vol.19 , pp. 3793-3800
    • Tomlinson, R.L.1    Abreu, E.B.2    Ziegler, T.3    Ly, H.4    Counter, C.M.5    Terns, R.M.6    Terns, M.P.7
  • 45
    • 58249116118 scopus 로고    scopus 로고
    • Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP
    • 1:CAS:528:DC%2BD1MXhs1Ojurg%3D 19095616 10.1261/rna.1354009
    • Trahan C, Dragon F (2009) Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP. RNA 15:235-243
    • (2009) RNA , vol.15 , pp. 235-243
    • Trahan, C.1    Dragon, F.2
  • 46
    • 63649111958 scopus 로고    scopus 로고
    • A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles
    • 1:CAS:528:DC%2BD1MXls1SrsL8%3D 2700737 19285445 10.1016/j.molcel.2009.02. 020
    • Tycowski KT, Shu MD, Kukoyi A, Steitz JA (2009) A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles. Mol Cell 34:47-57
    • (2009) Mol Cell , vol.34 , pp. 47-57
    • Tycowski, K.T.1    Shu, M.D.2    Kukoyi, A.3    Steitz, J.A.4
  • 47
    • 65949117219 scopus 로고    scopus 로고
    • TCAB1: Driving telomerase to Cajal bodies
    • 1:CAS:528:DC%2BD1MXmvFCitbs%3D 19342896 10.4161/cc.8.9.8288
    • Venteicher AS, Artandi SE (2009) TCAB1: driving telomerase to Cajal bodies. Cell Cycle 8:1329-1331
    • (2009) Cell Cycle , vol.8 , pp. 1329-1331
    • Venteicher, A.S.1    Artandi, S.E.2
  • 48
    • 40749135820 scopus 로고    scopus 로고
    • Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly
    • DOI 10.1016/j.cell.2008.01.019, PII S0092867408001190
    • Venteicher AS, Meng Z, Mason PJ, Veenstra TD, Artandi SE (2008) Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Cell 132:945-957 (Pubitemid 351381739)
    • (2008) Cell , vol.132 , Issue.6 , pp. 945-957
    • Venteicher, A.S.1    Meng, Z.2    Mason, P.J.3    Veenstra, T.D.4    Artandi, S.E.5
  • 49
    • 59149095154 scopus 로고    scopus 로고
    • A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis
    • 1:CAS:528:DC%2BD1MXhtVOgu7c%3D 2728071 19179534 10.1126/science.1165357
    • Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE (2009) A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science 323:644-648
    • (2009) Science , vol.323 , pp. 644-648
    • Venteicher, A.S.1    Abreu, E.B.2    Meng, Z.3    McCann, K.E.4    Terns, R.M.5    Veenstra, T.D.6    Terns, M.P.7    Artandi, S.E.8
  • 50
    • 2442542173 scopus 로고    scopus 로고
    • Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins
    • DOI 10.1038/sj.emboj.7600181
    • Wang C, Meier UT (2004) Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins. EMBO J 23:1857-1867 (Pubitemid 38649648)
    • (2004) EMBO Journal , vol.23 , Issue.8 , pp. 1857-1867
    • Wang, C.1    Meier, U.T.2
  • 51
  • 52
    • 84864607108 scopus 로고    scopus 로고
    • TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends
    • 1:CAS:528:DC%2BC38XhtFGrtL3N 3516183 22863003 10.1016/j.cell.2012.07.012
    • Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE (2012) TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends. Cell 150:481-494
    • (2012) Cell , vol.150 , pp. 481-494
    • Zhong, F.L.1    Batista, L.F.2    Freund, A.3    Pech, M.F.4    Venteicher, A.S.5    Artandi, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.