메뉴 건너뛰기




Volumn 86, Issue , 2014, Pages 192-202

Neuroprotective and neurotrophic effects of Apigenin and Luteolin in MPTP induced parkinsonism in mice

Author keywords

Apigenin; Luteolin; Neuroprotective; Neurotrophic; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; APIGENIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BROMOCRIPTINE; GLIAL FIBRILLARY ACIDIC PROTEIN; LUTEOLIN; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE; NEUROPROTECTIVE AGENT; CATALASE; GLUTATHIONE; PROBENECID; SUPEROXIDE DISMUTASE;

EID: 84907311915     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.07.012     Document Type: Article
Times cited : (163)

References (54)
  • 1
    • 0000024078 scopus 로고
    • Catalase
    • H.U. Bergmeyer, Academic Press, Inc. New York
    • H. Aebi Catalase H.U. Bergmeyer, Methods of Enzymatic Analysis vol. 2 1974 Academic Press, Inc. New York 673 684
    • (1974) Methods of Enzymatic Analysis , vol.2 , pp. 673-684
    • Aebi, H.1
  • 2
    • 84879335548 scopus 로고    scopus 로고
    • Polyphenols: Multipotent therapeutic agents in neurodegenerative diseases
    • K.S. Bhullar, and H.P.V. Rupasinghe Polyphenols: multipotent therapeutic agents in neurodegenerative diseases Oxid. Med. Cell. Longev. 2013 1 18
    • (2013) Oxid. Med. Cell. Longev. , pp. 1-18
    • Bhullar, K.S.1    Rupasinghe, H.P.V.2
  • 3
    • 5744233877 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor
    • DOI 10.1080/08977190410001723308
    • D.K. Binder, and H.E. Scharfman Brain-derived neurotrophic factor Growth Factors 22 2004 123 131 (Pubitemid 39377904)
    • (2004) Growth Factors , vol.22 , Issue.3 , pp. 123-131
    • Binder, D.K.1    Scharfman, H.E.2
  • 4
    • 84878643838 scopus 로고    scopus 로고
    • The MPTP/Probenecid model of progressive Parkinson's disease
    • A.R. Carta, E. Carboni, and S. Spiga The MPTP/Probenecid model of progressive Parkinson's disease Methods Mol. Biol. 964 2013 295 308
    • (2013) Methods Mol. Biol. , vol.964 , pp. 295-308
    • Carta, A.R.1    Carboni, E.2    Spiga, S.3
  • 7
    • 84855394783 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction, and aging
    • H. Cui, Y. Kong, and H. Zhang Oxidative stress, mitochondrial dysfunction, and aging J. Signal Transduct. 2012 1 13
    • (2012) J. Signal Transduct. , pp. 1-13
    • Cui, H.1    Kong, Y.2    Zhang, H.3
  • 8
    • 0035807932 scopus 로고    scopus 로고
    • Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease
    • K.P. Datla, M. Christidou, W.W. Widmer, H.K. Rooprai, and D.T. Dexter Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease Neuroreport 12 2001 3871 3875 (Pubitemid 33105188)
    • (2001) NeuroReport , vol.12 , Issue.17 , pp. 3871-3875
    • Datla, K.P.1    Christidou, M.2    Widmer, W.W.3    Rooprai, H.K.4    Dexter, D.T.5
  • 9
    • 79952449396 scopus 로고    scopus 로고
    • Tyrosine hydroxylase and regulation of dopamine synthesis
    • S.C. Daubner, T. Le, and S. Wang Tyrosine hydroxylase and regulation of dopamine synthesis Arch. Biochem. Biophys. 508 2011 1 12
    • (2011) Arch. Biochem. Biophys. , vol.508 , pp. 1-12
    • Daubner, S.C.1    Le, T.2    Wang, S.3
  • 10
    • 0033033276 scopus 로고    scopus 로고
    • Tyrosine hydroxylase-immunoreactive neurons are decreased in number in the cerebral cortex of Parkinson's disease
    • DOI 10.1046/j.1440-1789.1999.00196.x
    • T. Fukuda, J. Takahashi, and J. Tanaka Tyrosine Hydroxylase- immunoreactive neurons are decreased in number in the cerebral cortex of Parkinson's disease Neuropathology 19 1999 10 13 (Pubitemid 29101433)
    • (1999) Neuropathology , vol.19 , Issue.1 , pp. 10-13
    • Fukuda, T.1    Takahashi, J.2    Tanaka, J.3
  • 11
    • 80051896049 scopus 로고    scopus 로고
    • Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
    • M. Funakoshi-Tago, K. Nakamura, K. Tago, T. Mashino, and T. Kasahara Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin Int. Immunopharmacol. 11 2011 1150 1159
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 1150-1159
    • Funakoshi-Tago, M.1    Nakamura, K.2    Tago, K.3    Mashino, T.4    Kasahara, T.5
  • 12
    • 84868251080 scopus 로고    scopus 로고
    • Whole animal perfusion fixation for rodents
    • G.J. Gage, D.R. Kipke, and W. Shain Whole animal perfusion fixation for rodents J. Vis. Exp. 65 2012 1 9
    • (2012) J. Vis. Exp. , vol.65 , pp. 1-9
    • Gage, G.J.1    Kipke, D.R.2    Shain, W.3
  • 15
    • 0027300736 scopus 로고
    • Lipid peroxidation: Its mechanism, measurement, and significance
    • B. Halliwell, and S. Chirico Lipid peroxidation: its mechanism, measurement, and significance Am. J. Clin. Nutr. 57 1993 15S 25S
    • (1993) Am. J. Clin. Nutr. , vol.57
    • Halliwell, B.1    Chirico, S.2
  • 16
    • 5444225223 scopus 로고    scopus 로고
    • Postmortem studies in Parkinson's disease
    • A. Hartmann Postmortem studies in Parkinson's disease Dialogues Clin. Neurosci. 6 2004 281 293 (Pubitemid 39362560)
    • (2004) Dialogues in Clinical Neuroscience , vol.6 , Issue.3 , pp. 281-293
    • Hartmann, A.1
  • 17
    • 0033121299 scopus 로고    scopus 로고
    • FcεRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-α in glial cells
    • S. Hunot, N. Dugas, B. Faucheux, A. Hartmann, M. Tardieu, D. Patrice, Y. Agid, B. Dugas, and E.C. Hirsch FcqRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-α in glial cells J. Neurosci. 19 1999 3440 3447 (Pubitemid 29203124)
    • (1999) Journal of Neuroscience , vol.19 , Issue.9 , pp. 3440-3447
    • Hunot, S.1    Dugas, N.2    Faucheux, B.3    Hartmann, A.4    Tardieu, M.5    Debre, P.6    Agid, Y.7    Dugas, B.8    Hirsch, E.C.9
  • 18
    • 34347259269 scopus 로고    scopus 로고
    • Protocol for the MPTP mouse model of Parkinson's disease
    • DOI 10.1038/nprot.2006.342, PII NPROT.2006.342
    • V. Jackson-Lewis, and S. Przedborski Protocol for the MPTP mouse model of Parkinson's disease Nat. Protoc. 2 2007 141 151 (Pubitemid 47044700)
    • (2007) Nature Protocols , vol.2 , Issue.1 , pp. 141-151
    • Jackson-Lewis, V.1    Przedborski, S.2
  • 19
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical features and diagnosis
    • DOI 10.1136/jnnp.2007.131045
    • J. Jankovic Parkinson's disease: clinical features and diagnosis J. Neurol. Neurosurg. Psychiatry 79 2008 368 376 (Pubitemid 351441488)
    • (2008) Journal of Neurology, Neurosurgery and Psychiatry , vol.79 , Issue.4 , pp. 368-376
    • Jankovic, J.1
  • 20
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • P. Jenner, and C.W. Olanow Oxidative stress and the pathogenesis of Parkinson's disease Neurology 47 1996 161 170
    • (1996) Neurology , vol.47 , pp. 161-170
    • Jenner, P.1    Olanow, C.W.2
  • 22
    • 84862836132 scopus 로고    scopus 로고
    • Improved pyrogallol autoxidation method: A reliable and cheap superoxide-scavenging assay suitable for all antioxidants
    • X. Li Improved pyrogallol autoxidation method: a reliable and cheap superoxide-scavenging assay suitable for all antioxidants J. Agric. Food Chem. 60 2012 6418 6424
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 6418-6424
    • Li, X.1
  • 23
    • 44549085003 scopus 로고    scopus 로고
    • Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage
    • J.H. Lim, K.M. Kim, S.W. Kim, O. Hwang, and H.J. Choi Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage Pharmacol. Res. 57 2008 325 331
    • (2008) Pharmacol. Res. , vol.57 , pp. 325-331
    • Lim, J.H.1    Kim, K.M.2    Kim, S.W.3    Hwang, O.4    Choi, H.J.5
  • 25
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of Disease: Astrocytes in neurodegenerative disease
    • DOI 10.1038/ncpneuro0355, PII NCPNEURO0355
    • N.J. Maragakis, and J.D. Rothstein Mechanisms of Disease: astrocytes in neurodegenerative Disease Nat. Clin. Practice:Neurol. 2 2006 679 689 (Pubitemid 44782682)
    • (2006) Nature Clinical Practice Neurology , vol.2 , Issue.12 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 26
    • 67349099098 scopus 로고    scopus 로고
    • Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats
    • S. Matsuda, M. Umeda, H. Uchida, H. Kato, and T. Araki Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats J. Neural Transm. 116 2009 395 404
    • (2009) J. Neural Transm. , vol.116 , pp. 395-404
    • Matsuda, S.1    Umeda, M.2    Uchida, H.3    Kato, H.4    Araki, T.5
  • 28
    • 84890470833 scopus 로고    scopus 로고
    • Adult neurogenesis in Parkinson's disease
    • H. Mochizuki Adult neurogenesis in Parkinson's disease Neurogenesis Adult Brain II 2011 23 36
    • (2011) Neurogenesis Adult Brain II , pp. 23-36
    • Mochizuki, H.1
  • 29
    • 17044382151 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions
    • P. Mohapel, H. Frielingsdorf, J. Häggblad, O. Zachrisson, and P. Brundin Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions Neuroscience 132 2005 767 776
    • (2005) Neuroscience , vol.132 , pp. 767-776
    • Mohapel, P.1    Frielingsdorf, H.2    Häggblad, J.3    Zachrisson, O.4    Brundin, P.5
  • 30
    • 33644526277 scopus 로고    scopus 로고
    • Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: Glia dictates resistance versus vulnerability to neurodegeneration
    • M.C. Morale, P.A. Serra, F. L'episcopo, C. Tirolo, S. Caniglia, N. Testa, F. Gennuso, and G. Giaquinta et al. Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration Neuroscience 138 2006 869 878
    • (2006) Neuroscience , vol.138 , pp. 869-878
    • Morale, M.C.1    Serra, P.A.2    L'Episcopo, F.3    Tirolo, C.4    Caniglia, S.5    Testa, N.6    Gennuso, F.7    Giaquinta, G.8
  • 31
    • 0031801548 scopus 로고    scopus 로고
    • Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity in mice
    • D. Muralikrishnan, and K.P. Mohanakumar Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice FASEB 12 1998 905 912 (Pubitemid 28294680)
    • (1998) FASEB Journal , vol.12 , Issue.10 , pp. 905-912
    • Muralikrishnan, D.1    Mohanakumar, K.P.2
  • 32
    • 51649151855 scopus 로고
    • Assay of superoxide dismutase activity in animal tissues
    • A. Nandi, and I.B. Chatterjee Assay of superoxide dismutase activity in animal tissues J. Biosci. 13 1988 305 315
    • (1988) J. Biosci. , vol.13 , pp. 305-315
    • Nandi, A.1    Chatterjee, I.B.2
  • 33
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • H. Ohkawa, O. Nobuko, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358 (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 35
    • 0001485756 scopus 로고    scopus 로고
    • MPTP: A review of its mechanisms of neurotoxicity
    • DOI 10.1016/S1566-2772(01)00019-6, PII S1566277201000196
    • S. Przedborski, and M. Vila MPTP: a review of its mechanisms of neurotoxicity Clin. Neurosci. Res. 1 2001 407 418 (Pubitemid 33665559)
    • (2001) Clinical Neuroscience Research , vol.1 , Issue.6 , pp. 407-418
    • Przedborski, S.1    Vila, M.2
  • 36
    • 78650510617 scopus 로고    scopus 로고
    • Measurement of lipid peroxidation
    • 2.4
    • C.A. Reilly, and S.D. Aust Measurement of lipid peroxidation Curr. Protoc. 1999 1 13 2.4
    • (1999) Curr. Protoc. , pp. 1-13
    • Reilly, C.A.1    Aust, S.D.2
  • 38
    • 49949151942 scopus 로고    scopus 로고
    • Time dependent changes of striatal interneurons after focal cerebral ischemia
    • M. Sakuma, N. Hayakawa, H. Kato, and T. Araki Time dependent changes of striatal interneurons after focal cerebral ischemia J. Neural Transm. 115 2008 413 422
    • (2008) J. Neural Transm. , vol.115 , pp. 413-422
    • Sakuma, M.1    Hayakawa, N.2    Kato, H.3    Araki, T.4
  • 39
    • 0031415450 scopus 로고    scopus 로고
    • Anxiolytic natural and synthetic flavonoid ligands of the central benzodiazepine receptor have no effect on memory tasks in rats
    • DOI 10.1016/S0091-3057(97)00054-3, PII S0091305797000543
    • J.B. Salgueiro, P. Ardenghi, M. Dias, M.B. Ferreira, I. Izquierdo, and J.H. Medina Anxiolytic natural and synthetic flavonoids ligands of the central benzodiazepine receptor have no effect on memory tasks in rats Pharmacol. Biochem. Behav. 58 1997 887 891 (Pubitemid 28108193)
    • (1997) Pharmacology Biochemistry and Behavior , vol.58 , Issue.4 , pp. 887-891
    • Salgueiro, J.B.1    Ardenghi, P.2    Dias, M.3    Ferreira, M.B.C.4    Izquierdo, I.5    Medina, J.H.6
  • 40
    • 0000178743 scopus 로고
    • Estimation of total and non-protein sulfydral groups in tissues with Ellman's reagent
    • J. Sedlak, and R.H. Lindsay Estimation of total and non-protein sulfydral groups in tissues with Ellman's reagent Anal. Biochem. 95 1968 351 358
    • (1968) Anal. Biochem. , vol.95 , pp. 351-358
    • Sedlak, J.1    Lindsay, R.H.2
  • 41
    • 0034750776 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative stress: Comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementia patients
    • DOI 10.1007/s007020170003
    • J.A. Serra, R.O. Dominguez, E.S. de Lustig, E.M. Guareschi, A.L. Famulari, E.L. Bartolome, and E.R. Marschoff Parkinson's disease is associated with oxidative stress: comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementia patients J. Neural Transm. 108 2001 1135 1148 (Pubitemid 33022763)
    • (2001) Journal of Neural Transmission , vol.108 , Issue.10 , pp. 1135-1148
    • Serra, J.A.1    Dominguez, R.O.2    De Lustig, E.S.3    Guareschi, E.M.4    Famulari, A.L.5    Bartolome, E.L.6    Marschoff, E.R.7
  • 42
    • 84856186262 scopus 로고    scopus 로고
    • Protective effect of apigenin in transgenic Drosophila Melanogaster model of Parkinson's disease
    • Y.H. Siddique, F. Naz, S. Jyoti, and M. Afzal Protective effect of apigenin in transgenic Drosophila Melanogaster model of Parkinson's disease Pharmacologyonline 3 2011 790 795
    • (2011) Pharmacologyonline , vol.3 , pp. 790-795
    • Siddique, Y.H.1    Naz, F.2    Jyoti, S.3    Afzal, M.4
  • 43
    • 0015353270 scopus 로고
    • Calorimetric assay of catalase
    • A.K. Sinha Calorimetric assay of catalase Anal. Biochem. 47 1972 389 394
    • (1972) Anal. Biochem. , vol.47 , pp. 389-394
    • Sinha, A.K.1
  • 44
    • 0024199997 scopus 로고
    • Assay of glutathione reductase in crude tissue homogenates using 5,5'-dithiobis(2-nitrobenzoic acid)
    • I.K. Smith, T.L. Vierheller, and C.A. Thorne Assay of glutathione reductase in crude tissue homogenates using 5,5'-dithiobis(2-nitrobenzoic acid) Anal. Biochem. 175 1988 408 413
    • (1988) Anal. Biochem. , vol.175 , pp. 408-413
    • Smith, I.K.1    Vierheller, T.L.2    Thorne, C.A.3
  • 45
    • 67649591915 scopus 로고    scopus 로고
    • Apigenin and related compounds stimulate adult neurogenesis
    • P. Taupin Apigenin and related compounds stimulate adult neurogenesis Expert Opin. Ther. Patents 19 2009 523 527
    • (2009) Expert Opin. Ther. Patents , vol.19 , pp. 523-527
    • Taupin, P.1
  • 46
    • 84875703698 scopus 로고    scopus 로고
    • Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson's disease
    • J.M. Taylor, B.S. Main, and P.J. Crack Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson's disease Neurochem. Int. 62 2013 803 819
    • (2013) Neurochem. Int. , vol.62 , pp. 803-819
    • Taylor, J.M.1    Main, B.S.2    Crack, P.J.3
  • 47
    • 34548726106 scopus 로고    scopus 로고
    • TNF-α inhibition as a treatment strategy for neurodegenerative disorders: New drug candidates and targets
    • DOI 10.2174/156720507781788873
    • D. Tweedie, K. Sambamurti, and N.H. Greig TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets Curr. Alzheimer Res. 4 2007 378 385 (Pubitemid 47421968)
    • (2007) Current Alzheimer Research , vol.4 , Issue.4 , pp. 378-385
    • Tweedie, D.1    Sambamurti, K.2    Greig, N.H.3
  • 48
    • 0029054098 scopus 로고
    • Apigenin, a component of Matricaria recutitaflowers, is a central benzodiazepine receptors-ligand with anxiolytic effects
    • H. Viola, C. Wasowski, M. Levi de Stein, C. Wolfman, R. Silveira, F. Dajas, J.H. Medina, and A.C. Paladini Apigenin, a component of Matricaria recutitaflowers, is a central benzodiazepine receptors-ligand with anxiolytic effects Planta Med. 61 1995 213 216
    • (1995) Planta Med. , vol.61 , pp. 213-216
    • Viola, H.1    Wasowski, C.2    Levi De Stein, M.3    Wolfman, C.4    Silveira, R.5    Dajas, F.6    Medina, J.H.7    Paladini, A.C.8
  • 49
    • 84877350585 scopus 로고    scopus 로고
    • Current advances in using neurotrophic factors to treat neurodegenerative disorders
    • A.M. Weissmiller, and C. Wu Current advances in using neurotrophic factors to treat neurodegenerative disorders Transl. Neurodegener. 1 2012 1 9
    • (2012) Transl. Neurodegener. , vol.1 , pp. 1-9
    • Weissmiller, A.M.1    Wu, C.2
  • 50
    • 75149164344 scopus 로고    scopus 로고
    • Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue
    • C.J. Weydert, and J.J. Cullen Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue Nat. Protoc. 5 2009 51 66
    • (2009) Nat. Protoc. , vol.5 , pp. 51-66
    • Weydert, C.J.1    Cullen, J.J.2
  • 51
    • 34247366072 scopus 로고    scopus 로고
    • Inflammation as a causative factor in the aetiology of Parkinson's disease
    • DOI 10.1038/sj.bjp.0707167, PII 0707167
    • P.S. Whitton Inflammation as a causative factor in the aetiology of Parkinson's disease Br. J. Pharmacol. 150 2007 963 976 (Pubitemid 46628616)
    • (2007) British Journal of Pharmacology , vol.150 , Issue.8 , pp. 963-976
    • Whitton, P.S.1
  • 54


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.