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Volumn 19, Issue 4, 2009, Pages 523-527

Apigenin and related compounds stimulate adult neurogenesis - Mars, Inc., the Salk Institute for Biological Studies: WO2008147483

Author keywords

Food intake; Food supplement; Learning and memory; Neural progenitor and stem cells; Neurons

Indexed keywords

3' METHYLQUERCETIN 3 O GLUCURONIDE; ACACETIN; AMENTOFLAVONE; APIGENIN; APIGENIN 4' O GLUCORONIDE; APIGENIN 4' O SULFATE 7 O GLUCORONIDE; APIGENIN 7 O GLUCORONIDE; APIGETRIN; BAICALEIN; BROXURIDINE; CHRYSERIOL; CHRYSIN; DIOSMENTIN; EPICATECHIN; FISETIN HYDRATE; GENISTEIN; GERALDOL; GROWTH PROMOTOR; ISOQUERCITRIN; ISORHAMNETIN; KAEMPFEROL; LUTEOLIN; LUTEOLIN 7 GLUCOSIDE; QUERCETIN; QUERCETIN 3 O GLUCORONIDE; QUERCETIN 3 SULFATE; QUERCETIN 3,4' DIGLUCOSIDE; QUERCETIN 4' O GLUCOSIDE; QUERCETIN GLUCOSIDE SULFATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 67649591915     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543770902721279     Document Type: Review
Times cited : (56)

References (31)
  • 2
    • 0037106145 scopus 로고    scopus 로고
    • Adult neurogenesis and neural stem cells of the central nervous system in mammals
    • DOI 10.1002/jnr.10378
    • Taupin P, Gage FH. Adult neurogenesis and neural stem cells of the central nervous system in mammals. J Neurosci Res 2002;69:745-749 (Pubitemid 34984691)
    • (2002) Journal of Neuroscience Research , vol.69 , Issue.6 , pp. 745-749
    • Taupin, P.1    Gage, F.H.2
  • 3
    • 0023712796 scopus 로고
    • Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections
    • Stanfield BB, Trice JE. Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections. Exp Brain Res 1988;72:399-406 (Pubitemid 18230984)
    • (1988) Experimental Brain Research , vol.72 , Issue.2 , pp. 399-406
    • Stanfield, B.B.1    Trice, J.E.2
  • 4
    • 0027302887 scopus 로고
    • Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat
    • DOI 10.1016/0306-4522(93)90335-D
    • Cameron HA, Woolley CS, McEwen BS, et al. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neurosci 1993;56:337-344 (Pubitemid 23274753)
    • (1993) Neuroscience , vol.56 , Issue.2 , pp. 337-344
    • Cameron, H.A.1    Woolley, C.S.2    McEwen, B.S.3    Gould, E.4
  • 5
    • 0037186524 scopus 로고    scopus 로고
    • Functional neurogenesis in the adult hippocampus
    • DOI 10.1038/4151030a
    • van Praag H, Schinder AF, Christie BR, et al. Functional neurogenesis in the adult hippocampus. Nature 2002;415:1030-1034 •• First evidence of physiological activity of newly generated neuronal cells in the adult brain. Newly generated neuronal cells were infected with retrovirus carrying green fluorescent protein and recorded electrophysiologically. (Pubitemid 34193451)
    • (2002) Nature , vol.415 , Issue.6875 , pp. 1030-1034
    • Van Praag, H.1    Schinder, A.F.2    Christle, B.R.3    Toni, N.4    Palmer, T.D.5    Gage, F.H.6
  • 6
    • 48149105674 scopus 로고    scopus 로고
    • Neurons born in the adult dentate gyrus form functional synapses with target cells
    • Toni N, Laplagne DA, Zhao C, et al. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nat Neurosci 2008;11:901-907
    • (2008) Nat Neurosci , vol.11 , pp. 901-907
    • Toni, N.1    Laplagne, D.A.2    Zhao, C.3
  • 7
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Original report of the isolation and characterization of neural progenitor and stem cells from the adult brain of mammals
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992;255:1707-1710 •• Original report of the isolation and characterization of neural progenitor and stem cells from the adult brain of mammals.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 9
    • 22244445189 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian central nervous system: Functionality and potential clinical interest
    • Taupin P. Adult neurogenesis in the mammalian central nervous system: functionality and potential clinical interest. Med Sci Monit 2005;11:RA247-52 (Pubitemid 40992207)
    • (2005) Medical Science Monitor , vol.11 , Issue.7
    • Taupin, P.1
  • 10
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • Kuhn HG, Dickinson-Anson H, Gage FH. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996;16:2027-2033 (Pubitemid 26144015)
    • (1996) Journal of Neuroscience , vol.16 , Issue.6 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 11
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • DOI 10.1038/6368
    • van Praag H, Kempermann G, Gage FH. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 1999;2:266-270 (Pubitemid 30491298)
    • (1999) Nature Neuroscience , vol.2 , Issue.3 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 13
    • 56349133647 scopus 로고    scopus 로고
    • Therapeutic neuronal stem cells: Patents at the forefront
    • Taupin P. Therapeutic neuronal stem cells: patents at the forefront. Expert Opin Ther Patents 2008;18:1107-1110
    • (2008) Expert Opin Ther Patents , vol.18 , pp. 1107-1110
    • Taupin, P.1
  • 15
    • 0034213864 scopus 로고    scopus 로고
    • Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla
    • DOI 10.1016/S0006-2952(00)00264-1, PII S0006295200002641
    • Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-1394 (Pubitemid 30177355)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.11 , pp. 1387-1394
    • Avallone, R.1    Zanoli, P.2    Puia, G.3    Kleinschnitz, M.4    Schreier, P.5    Baraldi, M.6
  • 16
    • 0034851475 scopus 로고    scopus 로고
    • Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
    • Miean KH, Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J Agric Food Chem 2001;49:3106-3112
    • (2001) J Agric Food Chem , vol.49 , pp. 3106-3112
    • Miean, K.H.1    Mohamed, S.2
  • 17
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • DOI 10.1016/0165-0270(84)90007-4
    • Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984;11:47-60 (Pubitemid 14088970)
    • (1984) Journal of Neuroscience Methods , vol.11 , Issue.1 , pp. 47-60
    • Morris, R.1
  • 18
    • 0026697724 scopus 로고
    • Neu N, a neuronal specific nuclear protein in vertebrates
    • Mullen RJ, Buck CR, Smith AM. Neu N, a neuronal specific nuclear protein in vertebrates. Development 1992;116:201-211
    • (1992) Development , vol.116 , pp. 201-211
    • Mullen, R.J.1    Buck, C.R.2    Smith, A.M.3
  • 19
    • 0033635021 scopus 로고    scopus 로고
    • FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor
    • Taupin P, Ray J, Fischer WH, et al. FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 2000;28:385-397
    • (2000) Neuron , vol.28 , pp. 385-397
    • Taupin, P.1    Ray, J.2    Fischer, W.H.3
  • 20
    • 0032970297 scopus 로고    scopus 로고
    • Expression of unphosphorylated class III β-tubulin isotype in neuroepithelial cells demonstrates neuroblast commitment and differentiation
    • Fanarraga ML, Avila J, Zabala JC. Expression of unphosphorylated class III beta-tubulin isotype in neuroepithelial cells demonstrates neuroblast commitment and differentiation. Eur J Neurosci 1999;11:517-527 (Pubitemid 29050453)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.2 , pp. 517-527
    • Fanarraga, M.L.1
  • 21
    • 0037072064 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(02)09420-5
    • Burns A, Byrne EJ, Maurer K. Alzheimer's disease. Lancet 2002;360:163-165 (Pubitemid 34786210)
    • (2002) Lancet , vol.360 , Issue.9327 , pp. 163-165
    • Burns, A.1    Byrne, E.J.2    Maurer, K.3
  • 22
    • 67649574177 scopus 로고    scopus 로고
    • Adult neurogenesis, neural stem cells and Alzheimer's disease: Developments, limitations, problems and promises
    • In press
    • Taupin P. Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promises. Curr Alzheimer Res 2008. In press
    • (2008) Curr Alzheimer Res
    • Taupin, P.1
  • 23
    • 1842481232 scopus 로고    scopus 로고
    • Lower Hippocampal Volume in Patients Suffering from depression: A Meta-Analysis
    • DOI 10.1176/appi.ajp.161.4.598
    • Campbell S, Marriott M, Nahmias C, et al. Lower hippocampal volume in patients suffering from depression: a meta-analysis. Am J Psychiatry 2004;161:598-607 (Pubitemid 38445502)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.4 , pp. 598-607
    • Campbell, S.1    Marriott, M.2    Nahmias, C.3    MacQueen, G.M.4
  • 24
    • 29744464724 scopus 로고    scopus 로고
    • Volume deficits of subcortical nuclei in mood disorders. A postmortem study
    • Bielau H, Trübner K, Krell D, et al. Volume deficits of subcortical nuclei in mood disorders. A postmortem study. Eur Arch Psychiatry Clin Neurosci 2005;255:401-412
    • (2005) Eur Arch Psychiatry Clin Neurosci , vol.255 , pp. 401-412
    • Bielau, H.1    Trübner, K.2    Krell, D.3
  • 25
    • 39549119463 scopus 로고    scopus 로고
    • Neurogenesis and the Effects of Antidepressants
    • Taupin P. Neurogenesis and the Effects of Antidepressants. Drug Target Insights 2006;1:13-17
    • (2006) Drug Target Insights , vol.1 , pp. 13-17
    • Taupin, P.1
  • 26
    • 0034607499 scopus 로고    scopus 로고
    • New neurons: Extraordinary evidence or extraordinary conclusion?
    • BrdU is a marker of DNA synthesis, not cell proliferation and neurogenesis. It labels cell undergoing cell proliferation, but also DNA repair, cell-cycle reentry, and DNA duplication without cell division, leading to polyploidy
    • Nowakowski RS, Hayes NL. New neurons: extraordinary evidence or extraordinary conclusion? Science 2000;288:771 • BrdU is a marker of DNA synthesis, not cell proliferation and neurogenesis. It labels cell undergoing cell proliferation, but also DNA repair, cell-cycle reentry, and DNA duplication without cell division, leading to polyploidy.
    • (2000) Science , vol.288 , pp. 771
    • Nowakowski, R.S.1    Hayes, N.L.2
  • 27
    • 0036469275 scopus 로고    scopus 로고
    • Neurogenesis in adult mammals: Some progress and problems
    • Gould E, Gross CG. Neurogenesis in adult mammals: some progress and problems. J Neurosci 2002;22:619-623 (Pubitemid 34141740)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 619-623
    • Gould, E.1    Gross, C.G.2
  • 28
    • 0036469278 scopus 로고    scopus 로고
    • Adult neurogenesis in mammals: An identity crisis
    • Rakic P. Adult neurogenesis in mammals: an identity crisis. J Neurosci 2002;22:614-618 (Pubitemid 34141739)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 614-618
    • Rakic, P.1
  • 29
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation
    • DOI 10.1016/j.brainresrev.2006.08.002, PII S0165017306001044
    • Taupin P. BrdU Immunohistochemistry for Studying Adult Neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res Rev 2007;53:198-214 (Pubitemid 44854215)
    • (2007) Brain Research Reviews , vol.53 , Issue.1 , pp. 198-214
    • Taupin, P.1
  • 30
    • 34249724412 scopus 로고    scopus 로고
    • Protocols for studying adult neurogenesis: Insights and recent developments
    • DOI 10.2217/17460751.2.1.51
    • Taupin P. Protocols for Studying Adult Neurogenesis: insights and recent developments. Regen Med 2007;2:51-62 (Pubitemid 46824412)
    • (2007) Regenerative Medicine , vol.2 , Issue.1 , pp. 51-62
    • Taupin, P.1
  • 31
    • 39549103279 scopus 로고    scopus 로고
    • Adult neurogenesis pharmacology in neurological diseases and disorders
    • DOI 10.1586/14737175.8.2.311
    • Taupin P. Adult neurogenesis pharmacology in neurological diseases and disorders. Expert Rev Neurother 2008;8:311-320 (Pubitemid 351281116)
    • (2008) Expert Review of Neurotherapeutics , vol.8 , Issue.2 , pp. 311-320
    • Taupin, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.